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6CF5
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Crystal structure of the A/Viet Nam/1203/2004(H5N1) influenza virus hemagglutinin in complex with small molecule N-Cyclohexyltaurine
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wilson, I.A, Kadam, R.U.
Deposit date:2018-02-13
Release date:2018-04-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:A small-molecule fragment that emulates binding of receptor and broadly neutralizing antibodies to influenza A hemagglutinin.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CFG
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BU of 6cfg by Molmil
Crystal structure of the A/Vietnam/1203/2004 (H5N1) influenza virus hemagglutinin in complex with small molecule JNJ4796
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
Authors:Kadam, R.U, Wilson, I.A.
Deposit date:2018-02-14
Release date:2019-02-13
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:A small-molecule fusion inhibitor of influenza virus is orally active in mice.
Science, 363, 2019
3UYX
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Crystal structures of globular head of 2009 pandemic H1N1 hemagglutinin
Descriptor: Hemagglutinin, NITRATE ION
Authors:Xuan, C.L, Shi, Y, Qi, J.X, Xiao, H.X, Gao, G.F.
Deposit date:2011-12-06
Release date:2012-10-24
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural vaccinology: structure-based design of influenza A virus hemagglutinin subtype-specific subunit vaccines
Protein Cell, 2, 2011
6WF0
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BU of 6wf0 by Molmil
Crystal Structure of Broadly Neutralizing Antibody 3I14 Bound to the Influenza A H3 Hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Harshbarger, W.D, Lockbaum, G.J, Deming, D.T, Attatippaholkun, N, Schiffer, C.A, Marasco, W.A.
Deposit date:2020-04-03
Release date:2020-11-25
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.46 Å)
Cite:Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses.
Nat Commun, 12, 2021
6WEZ
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BU of 6wez by Molmil
Crystal Structure of Broadly Neutralizing Antibody 3I14-D93N Mutant Bound to the Influenza A H3 Hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Hemagglutinin, ...
Authors:Harshbarger, W.D, Lockbaum, G.J, Deming, D.T, Attatippaholkun, N, Schiffer, C.A, Marasco, W.A.
Deposit date:2020-04-03
Release date:2020-11-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses.
Nat Commun, 12, 2021
6WIZ
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BU of 6wiz by Molmil
Crystal structure of Fab 54-1G05 bound to H1 influenza hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 54-1G05 heavy chain, Fab 54-1G05 light chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2020-04-11
Release date:2020-07-01
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor.
Cell Host Microbe, 28, 2020
6WZT
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BU of 6wzt by Molmil
CryoEM structure of influenza hemagglutinin A/Victoria/361/2011 in complex with cyno antibody 3B10
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cyno antibody heavy chain, ...
Authors:Qiu, Y, Zhou, Y, Darricarrere, N.
Deposit date:2020-05-14
Release date:2021-03-10
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Broad neutralization of H1 and H3 viruses by adjuvanted influenza HA stem vaccines in nonhuman primates.
Sci Transl Med, 13, 2021
4XKG
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BU of 4xkg by Molmil
Crystal structure of hemagglutinin from Taiwan (2013) H6N1 influenza virus in complex with 6'-SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ...
Authors:Tzarum, N, Zhu, X, Wilson, I.A.
Deposit date:2015-01-11
Release date:2015-04-01
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure and Receptor Binding of the Hemagglutinin from a Human H6N1 Influenza Virus.
Cell Host Microbe, 17, 2015
6HJR
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BU of 6hjr by Molmil
Structure of full-length Influenza Hemagglutinin with tilted transmembrane (A/duck/Alberta/35/76[H1N1])
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Benton, D.J, Rosenthal, P.B.
Deposit date:2018-09-04
Release date:2018-09-26
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Influenza hemagglutinin membrane anchor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4XNM
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BU of 4xnm by Molmil
Antibody Influenza H5 Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, H5.3 FAB Heavy Chain, H5.3 FAB Light Chain, ...
Authors:Winarski, K.L, Spiler, B.W.
Deposit date:2015-01-15
Release date:2015-07-15
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Vaccine-elicited antibody that neutralizes H5N1 influenza and variants binds the receptor site and polymorphic sites.
Proc.Natl.Acad.Sci.USA, 112, 2015
6WHK
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BU of 6whk by Molmil
Minimally mutated anti-influenza broadly neutralizing antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Fab Heavy Chain, ...
Authors:Bajic, G, Schmidt, A.G.
Deposit date:2020-04-08
Release date:2021-04-14
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Minimally mutated anti-influenza broadly neutralizing antibody
To Be Published
4XNQ
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BU of 4xnq by Molmil
Antibody hemagglutinin Complexes
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, H5.3 Light chain, H5.3 heavy chain, ...
Authors:Spiller, B.W, Winarski, K.L.
Deposit date:2015-01-15
Release date:2015-07-15
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Vaccine-elicited antibody that neutralizes H5N1 influenza and variants binds the receptor site and polymorphic sites.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XQO
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BU of 4xqo by Molmil
Crystal structure of hemagglutinin from Jiangxi-Donghu (2013) H10N8 influenza virus in complex with 6'-SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Tzarum, N, Zhang, H, Zhu, X, Wilson, I.A.
Deposit date:2015-01-19
Release date:2015-04-01
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A Human-Infecting H10N8 Influenza Virus Retains a Strong Preference for Avian-type Receptors.
Cell Host Microbe, 17, 2015
4XQ5
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BU of 4xq5 by Molmil
Human-infecting H10N8 influenza virus retains strong preference for avian-type receptors
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Tzarum, N, Zhang, H, Zhu, X, Wilson, I.A.
Deposit date:2015-01-19
Release date:2015-04-01
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.592 Å)
Cite:A Human-Infecting H10N8 Influenza Virus Retains a Strong Preference for Avian-type Receptors.
Cell Host Microbe, 17, 2015
6WXL
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BU of 6wxl by Molmil
Cryo-EM structure of the VRC315 clinical trial, vaccine-elicited, human antibody 1D12 in complex with an H7 SH13 HA trimer
Descriptor: 1D12 Light chain, 1D21 Heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2020-05-11
Release date:2021-06-09
Last modified:2022-06-22
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Structure of an influenza group 2-neutralizing antibody targeting the hemagglutinin stem supersite.
Structure, 2022
4HMG
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BU of 4hmg by Molmil
REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, CHAIN HA1, ...
Authors:Weis, W.I, Bruenger, A.T, Skehel, J.J, Wiley, D.C.
Deposit date:1989-09-11
Release date:1991-01-15
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Refinement of the influenza virus hemagglutinin by simulated annealing.
J.Mol.Biol., 212, 1990
4XKD
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BU of 4xkd by Molmil
Crystal structure of hemagglutinin from Taiwan (2013) H6N1 influenza virus
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
Authors:Tzarum, N, Zhu, X, Wilson, I.A.
Deposit date:2015-01-11
Release date:2015-04-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.482 Å)
Cite:Structure and Receptor Binding of the Hemagglutinin from a Human H6N1 Influenza Virus.
Cell Host Microbe, 17, 2015
6HJQ
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BU of 6hjq by Molmil
Structure of Full-length Influenza Hemagglutinin (A/duck/Alberta/35/76) in complex with FISW84 Fab Fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of FISW84 Fab, ...
Authors:Benton, D.J, Rosenthal, P.B.
Deposit date:2018-09-04
Release date:2018-09-26
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Influenza hemagglutinin membrane anchor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4HKX
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Influenza hemagglutinin in complex with CH67 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CH67 heavy chain, CH67 light chain, ...
Authors:Schmidt, A.G, Harrison, S.C.
Deposit date:2012-10-15
Release date:2012-11-21
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
6HJP
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BU of 6hjp by Molmil
Structure of Influenza Hemagglutinin ectodomain (A/duck/Alberta/35/76) in complex with FISW84 Fab Fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of FISW84 Fab Fragment, Hemagglutinin, ...
Authors:Benton, D.J, Rosenthal, P.B.
Deposit date:2018-09-04
Release date:2018-09-26
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Influenza hemagglutinin membrane anchor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4XKF
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BU of 4xkf by Molmil
Crystal structure of hemagglutinin from Taiwan (2013) H6N1 influenza virus in complex with LSTa
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ...
Authors:Tzarum, N, Zhu, X, Wilson, I.A.
Deposit date:2015-01-11
Release date:2015-03-25
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.446 Å)
Cite:Structure and Receptor Binding of the Hemagglutinin from a Human H6N1 Influenza Virus.
Cell Host Microbe, 17, 2015
4HLZ
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BU of 4hlz by Molmil
Crystal Structure of Fab C179 in Complex with a H2N2 influenza virus hemagglutinin
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dreyfus, C, Wilson, I.A.
Deposit date:2012-10-17
Release date:2013-04-17
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of a classical broadly neutralizing stem antibody in complex with a pandemic h2 influenza virus hemagglutinin.
J.Virol., 87, 2013
4XKE
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BU of 4xke by Molmil
Crystal structure of hemagglutinin from Taiwan (2013) H6N1 influenza virus in complex with 3'-SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ...
Authors:Tzarum, N, Zhu, X, Wilson, I.A.
Deposit date:2015-01-11
Release date:2015-04-01
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.356 Å)
Cite:Structure and Receptor Binding of the Hemagglutinin from a Human H6N1 Influenza Virus.
Cell Host Microbe, 17, 2015
3VUN
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BU of 3vun by Molmil
Crystal structure of a influenza A virus (A/Aichi/2/1968 H3N2) hemagglutinin in C2 space group.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Yasutake, Y, Suzuki, T, Kawaguchi, A, Nobusawa, E.
Deposit date:2012-07-02
Release date:2012-08-01
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a influenza A virus (A/Aichi/2/1968 H3N2) hemagglutinin in C2 space group
To be Published
6XGC
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CryoEM structure of influenza hemagglutinin A/Michigan/45/2015 in complex with cyno antibody 1C4
Descriptor: 1C4 Fab heavy chain, 1C4 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Qiu, Y, Zhou, Y.
Deposit date:2020-06-17
Release date:2021-03-10
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Broad neutralization of H1 and H3 viruses by adjuvanted influenza HA stem vaccines in nonhuman primates.
Sci Transl Med, 13, 2021

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