1OZP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ozp by Molmil](/molmil-images/mine/1ozp) | Crystal Structure of Rv0819 from Mycobacterium tuberculosis MshD-Mycothiol Synthase Acetyl-Coenzyme A Complex. | Descriptor: | ACETYL COENZYME *A, hypothetical protein Rv0819 | Authors: | Vetting, M.W, Roderick, S.L, Yu, M, Blanchard, J.S. | Deposit date: | 2003-04-09 | Release date: | 2003-09-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of mycothiol synthase (Rv0819) from Mycobacterium tuberculosis shows structural homology to the GNAT family of N-acetyltransferases. Protein Sci., 12, 2003
|
|
1P0H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1p0h by Molmil](/molmil-images/mine/1p0h) | Crystal Structure of Rv0819 from Mycobacterium Tuberculosis MshD-Mycothiol Synthase Coenzyme A Complex | Descriptor: | ACETYL COENZYME *A, COENZYME A, hypothetical protein Rv0819 | Authors: | Vetting, M.W, Roderick, S.L, Yu, M, Blanchard, J.S. | Deposit date: | 2003-04-10 | Release date: | 2003-09-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of mycothiol synthase (Rv0819) from Mycobacterium tuberculosis shows structural homology to the GNAT family of N-acetyltransferases. Protein Sci., 12, 2003
|
|
5YO2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yo2 by Molmil](/molmil-images/mine/5yo2) | The crystal structure of Rv2747 from Mycobacterium tuberculosis in complex with Acetyl CoA and L-Arginine | Descriptor: | ACETYL COENZYME *A, ARGININE, Amino-acid acetyltransferase | Authors: | Singh, E, Tiruttani Subhramanyam, U.K, Pal, R.K, Srinivasan, A, Gourinath, S, Das, U. | Deposit date: | 2017-10-26 | Release date: | 2018-11-07 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.997 Å) | Cite: | Structural insights into the substrate binding mechanism of novel ArgA from Mycobacterium tuberculosis Int. J. Biol. Macromol., 125, 2019
|
|
5YGE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yge by Molmil](/molmil-images/mine/5yge) | ArgA complexed with AceCoA and glutamate | Descriptor: | ACETYL COENZYME *A, Amino-acid acetyltransferase, CACODYLIC ACID, ... | Authors: | Yang, X, Wu, L, Ran, Y, Xu, A, Zhang, B, Yang, X, Zhang, R, Rao, Z, Li, J. | Deposit date: | 2017-09-22 | Release date: | 2017-10-11 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.039 Å) | Cite: | Crystal structure of l-glutamate N-acetyltransferase ArgA from Mycobacterium tuberculosis Biochim. Biophys. Acta, 1865, 2017
|
|
6ADD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6add by Molmil](/molmil-images/mine/6add) | The crystal structure of Rv2747 from Mycobacterium tuberculosis in complex with CoA and NLQ | Descriptor: | Amino-acid acetyltransferase, COENZYME A, N~2~-ACETYL-L-GLUTAMINE | Authors: | Das, U, Singh, E, Pal, R.K, Tiruttani Subhramanyam, U.K, Gourinath, S, Srinivasan, A. | Deposit date: | 2018-07-31 | Release date: | 2018-12-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Structural insights into the substrate binding mechanism of novel ArgA from Mycobacterium tuberculosis Int. J. Biol. Macromol., 125, 2019
|
|
6BBZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6bbz by Molmil](/molmil-images/mine/6bbz) | Room temperature neutron/X-ray structure of sisomicin bound AAC-VIa | Descriptor: | (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, AAC 3-VI protein, MAGNESIUM ION | Authors: | Cuneo, M.J, Kumar, P. | Deposit date: | 2017-10-20 | Release date: | 2018-02-28 | Last modified: | 2023-10-04 | Method: | NEUTRON DIFFRACTION (1.9 Å), X-RAY DIFFRACTION | Cite: | A low-barrier hydrogen bond mediates antibiotic resistance in a noncanonical catalytic triad. Sci Adv, 4, 2018
|
|
6BC4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6bc4 by Molmil](/molmil-images/mine/6bc4) | |
6J3O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6j3o by Molmil](/molmil-images/mine/6j3o) | Crystal structure of the human PCAF bromodomain in complex with compound 12 | Descriptor: | 3-methyl-2-[[(3~{R})-1-methylpiperidin-3-yl]amino]-5~{H}-pyrrolo[3,2-d]pyrimidin-4-one, Histone acetyltransferase KAT2B | Authors: | Huang, L.Y, Li, H, Li, L.L, Niu, L, Seupel, R, Wu, C.Y, Li, G.B, Yu, Y.M, Brennan, P.E, Yang, S.Y. | Deposit date: | 2019-01-05 | Release date: | 2019-05-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain. J.Med.Chem., 62, 2019
|
|
6BBR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6bbr by Molmil](/molmil-images/mine/6bbr) | |
6BC2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6bc2 by Molmil](/molmil-images/mine/6bc2) | |
6BC7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6bc7 by Molmil](/molmil-images/mine/6bc7) | Cryo X-ray structure of sisomicin bound AAC-VIa | Descriptor: | (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, AAC 3-VI protein, ACETATE ION | Authors: | Cuneo, M.J, Kumar, P. | Deposit date: | 2017-10-20 | Release date: | 2018-02-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A low-barrier hydrogen bond mediates antibiotic resistance in a noncanonical catalytic triad. Sci Adv, 4, 2018
|
|
6BC6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6bc6 by Molmil](/molmil-images/mine/6bc6) | Cryo X-ray structure of apo AAC-VIa | Descriptor: | AAC 3-VI protein, MAGNESIUM ION | Authors: | Cuneo, M.J, Kumar, P. | Deposit date: | 2017-10-20 | Release date: | 2018-02-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A low-barrier hydrogen bond mediates antibiotic resistance in a noncanonical catalytic triad. Sci Adv, 4, 2018
|
|
6BC3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6bc3 by Molmil](/molmil-images/mine/6bc3) | Cryo X-ray structure of sisomicin bound AAC-VIa | Descriptor: | (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, AAC 3-VI protein, COENZYME A | Authors: | Cuneo, M.J, Kumar, P, Serpersu, E.H. | Deposit date: | 2017-10-20 | Release date: | 2018-02-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.047 Å) | Cite: | A low-barrier hydrogen bond mediates antibiotic resistance in a noncanonical catalytic triad. Sci Adv, 4, 2018
|
|
6BC5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6bc5 by Molmil](/molmil-images/mine/6bc5) | |
2ZFN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zfn by Molmil](/molmil-images/mine/2zfn) | |
3BIY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3biy by Molmil](/molmil-images/mine/3biy) | Crystal structure of p300 histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA | Descriptor: | BROMIDE ION, Histone acetyltransferase p300, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R,20R)-20-carbamoyl-3-hydroxy-2,2-dimethyl-4,8,14,22-tetraoxo-12-thia-5,9,15,21-tetraazatricos-1-yl dihydrogen diphosphate | Authors: | Liu, X, Wang, L, Zhao, K, Thompson, P.R, Hwang, Y, Marmorstein, R, Cole, P.A. | Deposit date: | 2007-12-02 | Release date: | 2008-02-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The structural basis of protein acetylation by the p300/CBP transcriptional coactivator Nature, 451, 2008
|
|
1FY7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1fy7 by Molmil](/molmil-images/mine/1fy7) | CRYSTAL STRUCTURE OF YEAST ESA1 HISTONE ACETYLTRANSFERASE DOMAIN COMPLEXED WITH COENZYME A | Descriptor: | COENZYME A, ESA1 HISTONE ACETYLTRANSFERASE, SODIUM ION | Authors: | Yan, Y, Barlev, N.A, Haley, R.H, Berger, S.L, Marmorstein, R. | Deposit date: | 2000-09-28 | Release date: | 2000-11-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of yeast Esa1 suggests a unified mechanism for catalysis and substrate binding by histone acetyltransferases. Mol.Cell, 6, 2000
|
|
4IF5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4if5 by Molmil](/molmil-images/mine/4if5) | Structure of human Mec17 | Descriptor: | ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase, CHLORIDE ION | Authors: | Davenport, A.M, Collins, L, Minor, P, Sternberg, P, Hoelz, A. | Deposit date: | 2012-12-14 | Release date: | 2014-05-28 | Last modified: | 2014-07-02 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and Functional Characterization of the alpha-Tubulin Acetyltransferase MEC-17. J.Mol.Biol., 426, 2014
|
|
4JJX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4jjx by Molmil](/molmil-images/mine/4jjx) | Dodecameric structure of spermidine N-acetyltransferase SpeG from Vibrio cholerae O1 biovar eltor | Descriptor: | Spermidine n1-acetyltransferase | Authors: | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Kuhn, M.L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-03-08 | Release date: | 2013-04-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | A Novel Polyamine Allosteric Site of SpeG from Vibrio cholerae Is Revealed by Its Dodecameric Structure. J.Mol.Biol., 427, 2015
|
|
4KSA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ksa by Molmil](/molmil-images/mine/4ksa) | Crystal Structure of Malonyl-CoA decarboxylase from Rhodopseudomonas palustris, Northeast Structural Genomics Consortium Target RpR127 | Descriptor: | MAGNESIUM ION, Malonyl-CoA decarboxylase | Authors: | Forouhar, F, Neely, H, Seetharaman, J, Sahdev, S, Xiao, R, Patel, D.J, Ciccosanti, C, Wang, D, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2013-05-17 | Release date: | 2013-06-19 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structures of malonyl-coenzyme a decarboxylase provide insights into its catalytic mechanism and disease-causing mutations. Structure, 21, 2013
|
|
4KSF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ksf by Molmil](/molmil-images/mine/4ksf) | Crystal Structure of Malonyl-CoA decarboxylase from Agrobacterium vitis, Northeast Structural Genomics Consortium Target RiR35 | Descriptor: | CHLORIDE ION, Malonyl-CoA decarboxylase, NICKEL (II) ION | Authors: | Forouhar, F, Neely, H, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2013-05-17 | Release date: | 2013-06-19 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structures of malonyl-coenzyme a decarboxylase provide insights into its catalytic mechanism and disease-causing mutations. Structure, 21, 2013
|
|
4KS9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ks9 by Molmil](/molmil-images/mine/4ks9) | Crystal Structure of Malonyl-CoA decarboxylase (Rmet_2797) from Cupriavidus metallidurans, Northeast Structural Genomics Consortium Target CrR76 | Descriptor: | MAGNESIUM ION, Malonyl-CoA decarboxylase | Authors: | Forouhar, F, Tran, T.H, Lew, S, Seetharaman, J, Xiao, R, Acton, T.B, Everett, J.K, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2013-05-17 | Release date: | 2013-06-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of malonyl-coenzyme a decarboxylase provide insights into its catalytic mechanism and disease-causing mutations. Structure, 21, 2013
|
|
4LUA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4lua by Molmil](/molmil-images/mine/4lua) | |
4K30
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4k30 by Molmil](/molmil-images/mine/4k30) | Structure of the N-acetyltransferase domain of human N-acetylglutamate synthase | Descriptor: | N-ACETYL-L-GLUTAMATE, N-acetylglutamate synthase, mitochondrial | Authors: | Shi, D, Zhao, G, Jin, Z, Allewell, N.M, Tuchman, M. | Deposit date: | 2013-04-10 | Release date: | 2013-08-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.103 Å) | Cite: | Crystal structure of the N-acetyltransferase domain of human N-acetyl-L-glutamate synthase in complex with N-acetyl-L-glutamate provides insights into its catalytic and regulatory mechanisms. Plos One, 8, 2013
|
|
4MHD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mhd by Molmil](/molmil-images/mine/4mhd) | Crystal structure of spermidine N-acetyltransferase from Vibrio cholerae in complex with spermidine | Descriptor: | SPERMIDINE, Spermidine n1-acetyltransferase | Authors: | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Kuhn, M.L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-08-29 | Release date: | 2013-09-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | A Novel Polyamine Allosteric Site of SpeG from Vibrio cholerae Is Revealed by Its Dodecameric Structure. J.Mol.Biol., 427, 2015
|
|