PDB: 7717 resultsInfo pagesStatus searchChemie searchBIRD

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8SOU	Proteinase K Multiconformer Model at 363K Descriptor: ALA-ALA-ALA-SER-VAL-LYS, CALCIUM ION, Proteinase K, ... Authors: Du, S, Wankowicz, S, Yabukarski, F, Doukov, T, Herschlag, D, Fraser, J.S. Deposit date: 2023-04-30 Release date: 2023-08-09 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Refinement of multiconformer ensemble models from multi-temperature X-ray diffraction data. Methods Enzymol., 688, 2023
8SQV	Proteinase K Multiconformer Model at 333K Descriptor: CALCIUM ION, Proteinase K, SULFATE ION Authors: Du, S, Wankowicz, S, Yabukarski, F, Doukov, T, Herschlag, D, Fraser, J.S. Deposit date: 2023-05-04 Release date: 2023-08-09 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.22 Å) Cite: Refinement of multiconformer ensemble models from multi-temperature X-ray diffraction data. Methods Enzymol., 688, 2023
8FNJ	Structure of E138K/G140A HIV-1 intasome with Dolutegravir bound Descriptor: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... Authors: Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. Deposit date: 2022-12-27 Release date: 2023-08-09 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
8SOG	Proteinase K Multiconformer Model at 313K Descriptor: CALCIUM ION, Proteinase K, SULFATE ION Authors: Du, S, Wankowicz, S, Yabukarski, F, Doukov, T, Herschlag, D, Fraser, J.S. Deposit date: 2023-04-28 Release date: 2023-08-09 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.13 Å) Cite: Refinement of multiconformer ensemble models from multi-temperature X-ray diffraction data. Methods Enzymol., 688, 2023
8FNN	Structure of E138K/G140A/Q148K HIV-1 intasome with Dolutegravir bound Descriptor: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... Authors: Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. Deposit date: 2022-12-27 Release date: 2023-08-09 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
8FND	Structure of E138K HIV-1 intasome with Dolutegravir bound Descriptor: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... Authors: Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. Deposit date: 2022-12-27 Release date: 2023-08-09 Method: ELECTRON MICROSCOPY (3 Å) Cite: Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
8FN7	Structure of WT HIV-1 intasome bound to Dolutegravir Descriptor: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... Authors: Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. Deposit date: 2022-12-27 Release date: 2023-08-09 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
8FNO	Structure of E138K/G140A/Q148R HIV-1 intasome with Dolutegravir bound Descriptor: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... Authors: Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. Deposit date: 2022-12-28 Release date: 2023-08-09 Last modified: 2023-09-20 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
8FNL	Structure of E138K/Q148K HIV-1 intasome with Dolutegravir bound Descriptor: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... Authors: Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. Deposit date: 2022-12-27 Release date: 2023-08-09 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
8FNH	Structure of Q148K HIV-1 intasome with Dolutegravir bound Descriptor: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... Authors: Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. Deposit date: 2022-12-27 Release date: 2023-08-09 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
8FNP	Structure of E138K/G140S/Q148H HIV-1 intasome with Dolutegravir bound Descriptor: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... Authors: Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. Deposit date: 2022-12-28 Release date: 2023-08-09 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.2 Å) Cite: Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
8FNG	Structure of E138K HIV-1 intasome with Dolutegravir bound Descriptor: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... Authors: Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. Deposit date: 2022-12-27 Release date: 2023-08-09 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.2 Å) Cite: Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
8FNM	Structure of G140A/Q148K HIV-1 intasome with Dolutegravir bound Descriptor: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... Authors: Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. Deposit date: 2022-12-27 Release date: 2023-08-09 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
8FNQ	Structure of E138K/G140A/Q148K HIV-1 intasome with 4d bound Descriptor: 4-amino-N-[(2,4-difluorophenyl)methyl]-1-hydroxy-6-(6-hydroxyhexyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide, DNA (25-MER), DNA (27-MER), ... Authors: Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. Deposit date: 2022-12-28 Release date: 2023-08-09 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
8OKR	virus enhancing amyloid fibril formed by CKFKFQF Descriptor: PNF-18 Authors: Heerde, T, Schmidt, M, Faendrich, M. Deposit date: 2023-03-29 Release date: 2023-08-02 Method: ELECTRON MICROSCOPY (2.86 Å) Cite: Cryo-EM structure and polymorphic maturation of a viral transduction enhancing amyloid fibril. Nat Commun, 14, 2023
8ONQ	Structure of the amyloid-forming peptide Ac-EFIAWL from human GLP-1 Descriptor: Peptide Ac-EFIAWL from hGLP-1 Authors: Durvanger, Z. Deposit date: 2023-04-03 Release date: 2023-08-02 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation. Nat Commun, 14, 2023
8ANH	Structure of the amyloid-forming peptide LYIQWL from Tc5b, grown from 30% acetonitrile Descriptor: ACETONITRILE, Peptide LYIQWL from Tc5b, trifluoroacetic acid Authors: Durvanger, Z. Deposit date: 2022-08-05 Release date: 2023-08-02 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation. Nat Commun, 14, 2023
8ANM	Structure of the amyloid-forming peptide LYIQWL from Tc5b, grown from water Descriptor: Peptide LYIQWL from Tc5b Authors: Durvanger, Z. Deposit date: 2022-08-05 Release date: 2023-08-02 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (0.9 Å) Cite: Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation. Nat Commun, 14, 2023
8ANN	Structure of the amyloid-forming peptide LFIEWL from exendin-4, grown from acetonitrile / water Descriptor: Peptide LFIEWL from exendin-4 Authors: Durvanger, Z. Deposit date: 2022-08-05 Release date: 2023-08-02 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (1.24 Å) Cite: Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation. Nat Commun, 14, 2023
8ANL	Structure of the amyloid-forming peptide LFIEWL from exendin-4, grown from water Descriptor: Peptide LFIEWL from exendin-4 Authors: Durvanger, Z. Deposit date: 2022-08-05 Release date: 2023-08-02 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation. Nat Commun, 14, 2023
8ANI	Structure of the amyloid-forming peptide LYIQWL from Tc5b, grown from 10% ethanol Descriptor: ETHANOL, Peptide LYIQWL from Tc5b, trifluoroacetic acid Authors: Durvanger, Z. Deposit date: 2022-08-05 Release date: 2023-08-02 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation. Nat Commun, 14, 2023
8ANG	Structure of the amyloid-forming peptide LYIQWL from Tc5b, grown from 30% ethanol Descriptor: ETHANOL, Peptide LYIQWL from Tc5b Authors: Durvanger, Z. Deposit date: 2022-08-05 Release date: 2023-08-02 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation. Nat Commun, 14, 2023
8ANJ	Structure of the amyloid-forming peptide DFINWL from human GLP-2 Descriptor: Peptide DFINWL from human GLP-2 Authors: Durvanger, Z. Deposit date: 2022-08-05 Release date: 2023-08-02 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation. Nat Commun, 14, 2023
8ANK	Structure of the amyloid-forming peptide pEFIAWL from human GLP-1 Descriptor: Peptide pEFIAWL from hGLP-1 Authors: Durvanger, Z. Deposit date: 2022-08-05 Release date: 2023-08-02 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation. Nat Commun, 14, 2023
8PPO	First Intermediate Amyloid (FIA) - Tau Descriptor: Microtubule-associated protein tau Authors: Lovestam, S, Scheres, S.H.W, Goedert, M, Li, D. Deposit date: 2023-07-07 Release date: 2023-08-02 Last modified: 2024-01-24 Method: ELECTRON MICROSCOPY (2 Å) Cite: Disease-specific tau filaments assemble via polymorphic intermediates. Nature, 625, 2024

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