PDB: 17019 resultsInfo pagesStatus searchChemie searchBIRD

---

8RB6	Structure of Aldo-Keto Reductase 1C3 (AKR1C3) in complex with an inhibitor M689, with the 3-hydroxy-benzoisoxazole moiety. Resolution 2.0A Descriptor: 1,2-ETHANEDIOL, 4-[[4-(3-hydroxyphenyl)phenyl]amino]-1,2-benzoxazol-3-ol, Aldo-keto reductase family 1 member C3, ... Authors: Frydenvang, K, Mirza, O.A. Deposit date: 2023-12-03 Release date: 2024-03-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure-guided optimization of 3-hydroxybenzoisoxazole derivatives as inhibitors of Aldo-keto reductase 1C3 (AKR1C3) to target prostate cancer. Eur.J.Med.Chem., 268, 2024
2C2T	Human Dihydrofolate Reductase Complexed With NADPH and 2,4-Diamino-5-((7,8-dicarbaundecaboran-7-yl)methyl)-6-methylpyrimidine, a novel boron containing, nonclassical Antifolate Descriptor: (S)-2,4-DIAMINO-5-((7,8-DICARBAUNDECABORAN-7-YL)METHYL)-6-METHYLPYRIMIDINE, DIHYDROFOLATE REDUCTASE, GLYCEROL, ... Authors: leung, A.K.W, reynolds, R.C, riordan, J.M, borhani, D.W. Deposit date: 2005-09-30 Release date: 2007-04-10 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Novel Boron-Containing, Nonclassical Antifolates: Synthesis and Preliminary Biological and Structural Evaluation. J.Med.Chem., 50, 2007
3NF4	Crystal structure of acyl-CoA dehydrogenase from Mycobacterium thermoresistibile bound to flavin adenine dinucleotide Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, SODIUM ION, acyl-CoA dehydrogenase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-06-09 Release date: 2010-06-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
2C2S	Human Dihydrofolate Reductase Complexed With NADPH and 2,4-Diamino-5-(1-o-carboranylmethyl)-6-methylpyrimidine, A novel boron containing, nonclassical Antifolate Descriptor: 2,4-DIAMINO-5-(1-O-CARBORANYLMETHYL)-6-METHYLPYRIMIDINE, DIHYDROFOLATE REDUCTASE, GLYCEROL, ... Authors: Leung, A.K.W, Reynolds, R.C, Riordan, J.M, Borhani, D.W. Deposit date: 2005-09-29 Release date: 2007-04-10 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Novel Boron-Containing, Nonclassical Antifolates: Synthesis and Preliminary Biological and Structural Evaluation. J.Med.Chem., 50, 2007
3NWO	Crystal structure of Proline iminopeptidase Mycobacterium smegmatis Descriptor: 1,2-ETHANEDIOL, GLYCEROL, MAGNESIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-07-09 Release date: 2010-08-04 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3O0M	Crystal structure of a ZN-bound histidine triad family protein from Mycobacterium smegmatis Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ADENOSINE MONOPHOSPHATE, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-07-19 Release date: 2010-08-04 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3OC7	Crystal structure of an enoyl-CoA hydratase from Mycobacterium avium Descriptor: 1,2-ETHANEDIOL, Enoyl-CoA hydratase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-08-09 Release date: 2010-08-18 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3O38	Crystal structure of a short chain dehydrogenase from Mycobacterium smegmatis Descriptor: SODIUM ION, Short chain dehydrogenase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-07-23 Release date: 2010-08-11 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3OC6	Crystal structure of 6-phosphogluconolactonase from mycobacterium smegmatis, apo form Descriptor: 6-phosphogluconolactonase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-08-09 Release date: 2010-08-18 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3OI9	Crystal structure of molybdenum cofactor synthesis domain from Mycobacterium avium Descriptor: Molybdenum cofactor synthesis domain Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-08-18 Release date: 2010-09-01 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3P2Y	Crystal structure of alanine dehydrogenase/pyridine nucleotide transhydrogenase from Mycobacterium smegmatis Descriptor: 1,2-ETHANEDIOL, Alanine dehydrogenase/pyridine nucleotide transhydrogenase, CALCIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-10-04 Release date: 2010-10-13 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3ZH4	crystal structure of S. pneumoniae Hungary 19A MurA1 in complex with citrate Descriptor: CITRATE ANION, DI(HYDROXYETHYL)ETHER, UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE Authors: Gutierrez-Fernandez, J, Hermoso, J.A. Deposit date: 2012-12-20 Release date: 2013-04-24 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Heteroresistance to Fosfomycin is Predominant in Streptococcus Pneumoniae and Depends on Mura1 Gene. Antimicrob.Agents Chemother., 57, 2013
8OF2	Trypanosoma brucei pteridine reductase 1 (TbPTR1) in complex with 2,4,6 triamminopyrimidine (TAP) Descriptor: 1,2-ETHANEDIOL, ACETATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Tassone, G, Landi, G, Mangani, S, Pozzi, C. Deposit date: 2023-03-13 Release date: 2023-12-13 Method: X-RAY DIFFRACTION (1.48 Å) Cite: The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents. Eur.J.Med.Chem., 264, 2023
3P4T	Crystal structure of a putative acyl-CoA dehydrogenase from Mycobacterium smegmatis Descriptor: 1,2-ETHANEDIOL, Putative acyl-CoA dehydrogenase, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-[(4aS,10aR)-7,8-dimethyl-2,4-dioxo-1,3,4,4a,5,10a-hexahydrobenzo[g]pteridin-10(2H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-10-07 Release date: 2010-10-20 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3P0T	Crystal structure of an HIT-like protein from mycobacterium paratuberculosis Descriptor: 1,2-ETHANEDIOL, SULFATE ION, Uncharacterized protein Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-09-29 Release date: 2010-12-08 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3P85	Crystal structure enoyl-coa hydratase from mycobacterium avium Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CACODYLATE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-10-13 Release date: 2010-11-03 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3MPZ	Crystal structure of CYTIDINE DEAMINASE from Mycobacterium smegmatis Descriptor: Cytidine deaminase, ZINC ION Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-04-27 Release date: 2010-05-19 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3NDO	Crystal structure of deoxyribose phosphate aldolase from mycobacterium smegmatis Descriptor: AMMONIUM ION, Deoxyribose-phosphate aldolase, GLYCEROL, ... Authors: SSGCID, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-06-07 Release date: 2010-07-21 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3NDN	Crystal structure of O-succinylhomoserine sulfhydrylase from Mycobacterium tuberculosis covalently bound to pyridoxal-5-phosphate Descriptor: O-succinylhomoserine sulfhydrylase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-06-07 Release date: 2010-06-16 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3NG3	Crystal structure of deoxyribose phosphate aldolase from mycobacterium avium 104 in a schiff base with an unknown aldehyde Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Deoxyribose-phosphate aldolase, ... Authors: SSGCID, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-06-10 Release date: 2010-06-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3UVE	Crystal structure of Carveol dehydrogenase ((+)-trans-carveol dehydrogenase) from Mycobacterium avium Descriptor: 1,2-ETHANEDIOL, Carveol dehydrogenase ((+)-trans-carveol dehydrogenase), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2011-11-29 Release date: 2011-12-14 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3P4I	Crystal structure of acetate kinase from Mycobacterium avium Descriptor: 1,2-ETHANEDIOL, Acetate kinase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-10-06 Release date: 2010-11-10 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3P5M	Crystal structure of an enoyl-CoA hydratase/isomerase from Mycobacterium avium Descriptor: 1,2-ETHANEDIOL, Enoyl-CoA hydratase/isomerase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-10-08 Release date: 2010-10-27 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3PE8	Crystal structure of Enoyl-CoA hydratase from Mycobacterium smegmatis Descriptor: 1,2-ETHANEDIOL, Enoyl-CoA hydratase, ZINC ION Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-10-25 Release date: 2010-12-08 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3MYB	Crystal structure of enoyl-coa hydratase mycobacterium smegmatis Descriptor: Enoyl-CoA hydratase, GLYCEROL Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-05-10 Release date: 2010-06-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

<104105106107108109110111112113114115116117118119>