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5KFP	Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: reaction with 20 mM Mg2+ for 600s Descriptor: 2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE), CALCIUM ION, DIPHOSPHATE, ... Authors: Gao, Y, Yang, W. Deposit date: 2016-06-12 Release date: 2016-06-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
5KG0	Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 5 mM Mn2+ for 60s at 22 degree Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ... Authors: Gao, Y, Yang, W. Deposit date: 2016-06-12 Release date: 2016-06-29 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
5KFH	Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 90s Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... Authors: Gao, Y, Yang, W. Deposit date: 2016-06-12 Release date: 2016-06-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.72 Å) Cite: Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
5KFS	Human DNA polymerase eta R61A-DNA ternary complex: ground state at pH7.0 (K+ MES) with 1 Ca2+ ion Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Gao, Y, Yang, W. Deposit date: 2016-06-12 Release date: 2016-06-29 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.46 Å) Cite: Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
5KG3	Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 10 mM Mn2+ for 60s Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ... Authors: Gao, Y, Yang, W. Deposit date: 2016-06-12 Release date: 2016-06-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
5KFF	Human DNA polymerase eta-DNA ternary complex: reaction with 1 mM Mn2+ for 1800s Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Gao, Y, Yang, W. Deposit date: 2016-06-12 Release date: 2016-06-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
5KFQ	Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: reaction with 10 mM Mn2+ for 600s Descriptor: 2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE), CALCIUM ION, DIPHOSPHATE, ... Authors: Gao, Y, Yang, W. Deposit date: 2016-06-12 Release date: 2016-06-29 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
5KG2	Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 5 mM Mn2+ for 60s at 37 degree Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ... Authors: Gao, Y, Yang, W. Deposit date: 2016-06-12 Release date: 2016-06-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
5KFB	Human DNA polymerase eta-DNA ternary complex: reaction with 1 mM Mn2+ for 90s Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Gao, Y, Yang, W. Deposit date: 2016-06-12 Release date: 2016-06-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
5KFM	Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: ground state at pH7.0 (K+ MES) with 1 Ca2+ ion Descriptor: 2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE), CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Gao, Y, Yang, W. Deposit date: 2016-06-12 Release date: 2016-06-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
5KFI	Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 120s Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... Authors: Gao, Y, Yang, W. Deposit date: 2016-06-12 Release date: 2016-06-29 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
5KFW	Human DNA polymerase eta R61A-DNA ternary complex: reaction with 1 mM Mg2+ for 200s Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... Authors: Gao, Y, Yang, W. Deposit date: 2016-06-12 Release date: 2016-06-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
5KFT	Human DNA polymerase eta R61A-DNA ternary complex: reaction with 1 mM Mg2+ for 40s Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Gao, Y, Yang, W. Deposit date: 2016-06-12 Release date: 2016-06-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.52 Å) Cite: Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
5KG5	Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 10 mM Cd2+ for 60s Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ... Authors: Gao, Y, Yang, W. Deposit date: 2016-06-12 Release date: 2016-06-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
5L1I	Crystal Structure of Human DNA Polymerase Eta Inserting dCTP Opposite O6-Methyl-2'-deoxyguanosine Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*C)-3'), ... Authors: Patra, A, Egli, M. Deposit date: 2016-07-29 Release date: 2016-10-05 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.78 Å) Cite: Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase eta. J.Biol.Chem., 291, 2016
5L1L	PostInsertion complex of Human DNA Polymerase Eta bypassing an O6-Methyl-2'-deoxyguanosine : dT site Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*GP*(6OG)P*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Patra, A, Egli, M. Deposit date: 2016-07-29 Release date: 2016-10-05 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase eta. J.Biol.Chem., 291, 2016
5L1K	PostInsertion complex of Human DNA Polymerase Eta bypassing an O6-Methyl-2'-deoxyguanosine : dC site Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*C)-3'), DNA (5'-D(*CP*AP*TP*GP*(6OG)P*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Patra, A, Egli, M. Deposit date: 2016-07-29 Release date: 2016-10-05 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase eta. J.Biol.Chem., 291, 2016
5L9X	Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 60s Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... Authors: Gao, Y, Yang, W. Deposit date: 2016-06-12 Release date: 2016-06-22 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
5L1J	Crystal Structure of Human DNA Polymerase Eta Inserting dTMPNPP Opposite O6-Methyl-2'-deoxyguanosine Descriptor: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(6OG)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Patra, A, Egli, M. Deposit date: 2016-07-29 Release date: 2016-10-05 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.94 Å) Cite: Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase eta. J.Biol.Chem., 291, 2016
5KFY	Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 5 mM Mn2+ for 60s at 4 degree Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Gao, Y, Yang, W. Deposit date: 2016-06-12 Release date: 2016-06-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
5JUM	Crystal Structure of Human DNA Polymerase Eta Inserting dCTP Opposite N-(2'-deoxyguanosin-8- yl)-3-aminobenzanthrone (C8-dG-ABA) Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Patra, A, Politica, D.A, Stone, M.P, Egli, M. Deposit date: 2016-05-10 Release date: 2016-09-07 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Mechanism of Error-Free Bypass of the Environmental Carcinogen N-(2'-Deoxyguanosin-8-yl)-3-aminobenzanthrone Adduct by Human DNA Polymerase eta. Chembiochem, 17, 2016
1DGI	Cryo-EM structure of human poliovirus(serotype 1)complexed with three domain CD155 Descriptor: POLIOVIRUS RECEPTOR, VP1, VP2, ... Authors: He, Y, Bowman, V.D, Mueller, S, Bator, C.M, Bella, J, Peng, X, Baker, T.S, Wimmer, E, Kuhn, R.J, Rossmann, M.G. Deposit date: 1999-11-24 Release date: 2000-01-24 Last modified: 2024-02-07 Method: ELECTRON MICROSCOPY (22 Å) Cite: Interaction of the poliovirus receptor with poliovirus. Proc.Natl.Acad.Sci.USA, 97, 2000
1TQL	POLIOVIRUS POLYMERASE G1A MUTANT Descriptor: ACETIC ACID, RNA-directed RNA polymerase Authors: Thompson, A.A, Peersen, O.B. Deposit date: 2004-06-17 Release date: 2004-08-17 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase Embo J., 23, 2004
1HXS	CRYSTAL STRUCTURE OF MAHONEY STRAIN OF POLIOVIRUS AT 2.2A RESOLUTION Descriptor: GENOME POLYPROTEIN, COAT PROTEIN VP1, COAT PROTEIN VP2, ... Authors: Miller, S.T, Hogle, J.M, Filman, D.J. Deposit date: 2001-01-16 Release date: 2002-01-16 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Ab initio phasing of high-symmetry macromolecular complexes: successful phasing of authentic poliovirus data to 3.0 A resolution. J.Mol.Biol., 307, 2001
1VBD	POLIOVIRUS (TYPE 1, MAHONEY STRAIN) COMPLEXED WITH R78206 Descriptor: (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY Authors: Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M. Deposit date: 1996-01-02 Release date: 1996-07-11 Last modified: 2023-04-19 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design. Curr.Biol., 4, 1994

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