2GU4
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2P99
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![BU of 2p99 by Molmil](/molmil-images/mine/2p99) | E. coli methionine aminopeptidase monometalated with inhibitor YE6 | Descriptor: | 5-(2-chlorophenyl)furan-2-carbohydrazide, MANGANESE (II) ION, Methionine aminopeptidase, ... | Authors: | Ye, Q. | Deposit date: | 2007-03-24 | Release date: | 2007-11-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Inhibition of Monometalated Methionine Aminopeptidase: Inhibitor Discovery and Crystallographic Analysis. J.Med.Chem., 50, 2007
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2MAT
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![BU of 2mat by Molmil](/molmil-images/mine/2mat) | E.COLI METHIONINE AMINOPEPTIDASE AT 1.9 ANGSTROM RESOLUTION | Descriptor: | COBALT (II) ION, PROTEIN (METHIONINE AMINOPEPTIDASE), SODIUM ION | Authors: | Lowther, W.T, Orville, A.M, Madden, D.T, Lim, S, Rich, D.H, Matthews, B.W. | Deposit date: | 1999-03-29 | Release date: | 1999-06-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis. Biochemistry, 38, 1999
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2Q92
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![BU of 2q92 by Molmil](/molmil-images/mine/2q92) | E. coli methionine aminopeptidase Mn-form with inhibitor B23 | Descriptor: | 5-(2-NITROPHENYL)-2-FUROIC ACID, MANGANESE (II) ION, Methionine aminopeptidase, ... | Authors: | Ye, Q.-Z. | Deposit date: | 2007-06-12 | Release date: | 2008-01-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop flexibility in selective inhibition of bacterial enzymes. Bmc Struct.Biol., 7, 2007
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1C27
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![BU of 1c27 by Molmil](/molmil-images/mine/1c27) | E. COLI METHIONINE AMINOPEPTIDASE:NORLEUCINE PHOSPHONATE COMPLEX | Descriptor: | (1-AMINO-PENTYL)-PHOSPHONIC ACID, COBALT (II) ION, METHIONINE AMINOPEPTIDASE, ... | Authors: | Lowther, W.T, Zhang, Y, Sampson, P.B, Honek, J.F, Matthews, B.W. | Deposit date: | 1999-07-22 | Release date: | 1999-11-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues. Biochemistry, 38, 1999
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4MAT
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![BU of 4mat by Molmil](/molmil-images/mine/4mat) | E.COLI METHIONINE AMINOPEPTIDASE HIS79ALA MUTANT | Descriptor: | PROTEIN (METHIONINE AMINOPEPTIDASE), SODIUM ION | Authors: | Lowther, W.T, Orville, A.M, Madden, D.T, Lim, S, Rich, D.H, Matthews, B.W. | Deposit date: | 1999-03-29 | Release date: | 1999-06-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis. Biochemistry, 38, 1999
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3MAT
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![BU of 3mat by Molmil](/molmil-images/mine/3mat) | E.COLI METHIONINE AMINOPEPTIDASE TRANSITION-STATE INHIBITOR COMPLEX | Descriptor: | COBALT (II) ION, METHIONINE AMINOPEPTIDASE, SODIUM ION, ... | Authors: | Lowther, W.T, Orville, A.M, Madden, D.T, Lim, S, Rich, D.H, Matthews, B.W. | Deposit date: | 1999-03-29 | Release date: | 1999-06-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis. Biochemistry, 38, 1999
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1C23
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![BU of 1c23 by Molmil](/molmil-images/mine/1c23) | E. COLI METHIONINE AMINOPEPTIDASE: METHIONINE PHOSPHONATE COMPLEX | Descriptor: | (1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHONIC ACID, COBALT (II) ION, METHIONINE AMINOPEPTIDASE, ... | Authors: | Lowther, W.T, Zhang, Y, Sampson, P.B, Honek, J.F, Matthews, B.W. | Deposit date: | 1999-07-22 | Release date: | 1999-11-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues. Biochemistry, 38, 1999
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2GTX
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![BU of 2gtx by Molmil](/molmil-images/mine/2gtx) | Structural Basis of Catalysis by Mononuclear Methionine Aminopeptidase | Descriptor: | (1-AMINO-PENTYL)-PHOSPHONIC ACID, MANGANESE (II) ION, Methionine aminopeptidase, ... | Authors: | Ye, Q.Z. | Deposit date: | 2006-04-28 | Release date: | 2006-07-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of catalysis by monometalated methionine aminopeptidase. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2GU7
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![BU of 2gu7 by Molmil](/molmil-images/mine/2gu7) | E. coli methionine aminopeptidase unliganded, 1:0.5 | Descriptor: | MANGANESE (II) ION, Methionine aminopeptidase, SODIUM ION | Authors: | Ye, Q.Z. | Deposit date: | 2006-04-28 | Release date: | 2006-07-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of catalysis by monometalated methionine aminopeptidase. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2GG5
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![BU of 2gg5 by Molmil](/molmil-images/mine/2gg5) | Novel bacterial methionine aminopeptidase inhibitors | Descriptor: | 5-IMINO-4-(2-TRIFLUOROMETHYL-PHENYLAZO)-5H-PYRAZOL-3-YLAMINE, COBALT (II) ION, Methionine aminopeptidase, ... | Authors: | Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M. | Deposit date: | 2006-03-23 | Release date: | 2006-06-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors. Proteins, 66, 2007
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2GGB
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![BU of 2ggb by Molmil](/molmil-images/mine/2ggb) | Novel bacterial methionine aminopeptidase inhibitors | Descriptor: | COBALT (II) ION, METHYL N-[(2S,3R)-3-AMINO-2-HYDROXYHEPTANOYL]-L-SERYL-L-LEUCINATE, Methionine aminopeptidase, ... | Authors: | Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M. | Deposit date: | 2006-03-23 | Release date: | 2006-06-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors. Proteins, 66, 2007
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3D27
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![BU of 3d27 by Molmil](/molmil-images/mine/3d27) | E. coli methionine aminopeptidase with Fe inhibitor W29 | Descriptor: | 4-(3-ethylthiophen-2-yl)benzene-1,2-diol, MANGANESE (II) ION, Methionine aminopeptidase | Authors: | Ye, Q.Z, Chai, S, He, H.Z. | Deposit date: | 2008-05-07 | Release date: | 2008-08-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of inhibitors of Escherichia coli methionine aminopeptidase with the Fe(II)-form selectivity and antibacterial activity. J.Med.Chem., 51, 2008
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1MAT
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6IZ7
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6IZI
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6J0A
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