8GOY
 
 | | SulE P44R | | 分子名称: | 5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methyl-pyrazole-4-carboxylic acid, Alpha/beta fold hydrolase, GLYCEROL | | 著者 | Liu, B, He, J, Ran, T, Wang, W. | | 登録日 | 2022-08-25 | | 公開日 | 2023-08-02 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.784 Å) | | 主引用文献 | Crystal structures of herbicide-detoxifying esterase reveal a lid loop affecting substrate binding and activity.
Nat Commun, 14, 2023
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8GP0
 | | crystal structure of SulE | | 分子名称: | Alpha/beta fold hydrolase, CITRIC ACID, GLYCEROL | | 著者 | Liu, B, Ran, T, wang, W, He, J. | | 登録日 | 2022-08-25 | | 公開日 | 2023-08-02 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Crystal structures of herbicide-detoxifying esterase reveal a lid loop affecting substrate binding and activity.
Nat Commun, 14, 2023
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8GOL
 | | crystal structure of SulE | | 分子名称: | 2-[(4-chloranyl-6-methoxy-pyrimidin-2-yl)carbamoylsulfamoyl]benzoic acid, Alpha/beta fold hydrolase, GLYCEROL | | 著者 | Liu, B, Ran, T, Wang, W, He, J. | | 登録日 | 2022-08-25 | | 公開日 | 2023-08-02 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structures of herbicide-detoxifying esterase reveal a lid loop affecting substrate binding and activity.
Nat Commun, 14, 2023
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8HEH
 | | Crystal structure of GCN5-related N-acetyltransferase 05790 | | 分子名称: | COENZYME A, GLYCEROL, GNAT family N-acetyltransferase | | 著者 | Xu, M.X, Ran, T.T, Wang, W. | | 登録日 | 2022-11-08 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal structure of prodigiosin binding protein PgbP, a GNAT family protein, in Serratia marcescens FS14.
Biochem.Biophys.Res.Commun., 640, 2022
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8H0M
 | | Crystal structure of VioD | | 分子名称: | (2S)-2-ethylhexan-1-ol, FLAVIN-ADENINE DINUCLEOTIDE, FORMIC ACID, ... | | 著者 | Xu, M, Ran, T, Wang, W. | | 登録日 | 2022-09-29 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | | 主引用文献 | Structural basis for substrate binding and catalytic mechanism of the key enzyme VioD in the violacein synthesis pathway.
Proteins, 91, 2023
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7E5A
 | | interferon-inducible anti-viral protein R356A | | 分子名称: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, Guanylate-binding protein 5, ... | | 著者 | Cui, W, Wang, W, Chen, C, Slater, B, Xiong, Y, Ji, X.Y, Yang, H.T. | | 登録日 | 2021-02-18 | | 公開日 | 2021-05-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
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8H46
 | | Blasnase-T13A/P55N with L-asn | | 分子名称: | ASPARAGINE, FORMIC ACID, GLYCEROL, ... | | 著者 | Lu, F, Wang, W, Chi, H, Ran, T. | | 登録日 | 2022-10-10 | | 公開日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure-based rational design of Bacillus licheniformis L-asparaginase with low/no D-asparaginase activity for a safer enzyme
To Be Published
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8H47
 | | Blasnase-T13A/P55F | | 分子名称: | FORMIC ACID, GLYCEROL, L-asparaginase, ... | | 著者 | Lu, F, Wang, W, Chi, H, Ran, T. | | 登録日 | 2022-10-10 | | 公開日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-based rational design of Bacillus licheniformis L-asparaginase with low/no D-asparaginase activity for a safer enzyme
To Be Published
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8H4B
 | | Blasnase-T13A/M57P with L-asn | | 分子名称: | ASPARAGINE, FORMIC ACID, L-asparaginase, ... | | 著者 | Lu, F, Wang, W, Chi, H, Ran, T. | | 登録日 | 2022-10-10 | | 公開日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure-based rational design of Bacillus licheniformis L-asparaginase with low/no D-asparaginase activity for a safer enzyme
To Be Published
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8H4D
 | | Blasnase-T13A/M57N | | 分子名称: | FORMIC ACID, GLYCEROL, L-asparaginase, ... | | 著者 | Lu, F, Wang, W, Chi, H, Ran, T. | | 登録日 | 2022-10-10 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-based rational design of Bacillus licheniformis L-asparaginase with low/no D-asparaginase activity for a safer enzyme
To Be Published
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8H44
 | | Blasnase-P55N | | 分子名称: | FORMIC ACID, L-asparaginase, MAGNESIUM ION | | 著者 | Lu, F, Wang, W, Chi, H, Ran, T. | | 登録日 | 2022-10-10 | | 公開日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure-based rational design of Bacillus licheniformis L-asparaginase with low/no D-asparaginase activity for a safer enzyme
To Be Published
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8H45
 | | Blasnase-T13A/P55N | | 分子名称: | FORMIC ACID, L-asparaginase, MAGNESIUM ION | | 著者 | Lu, F, Wang, W, Chi, H, Ran, T. | | 登録日 | 2022-10-10 | | 公開日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structure-based rational design of Bacillus licheniformis L-asparaginase with low/no D-asparaginase activity for a safer enzyme
To Be Published
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8H48
 | | Blasnase-T13A/P55F with L-asn | | 分子名称: | ASPARAGINE, FORMIC ACID, L-asparaginase, ... | | 著者 | Lu, F, Wang, W, Chi, H, Ran, T. | | 登録日 | 2022-10-10 | | 公開日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure-based rational design of Bacillus licheniformis L-asparaginase with low/no D-asparaginase activity for a safer enzyme
To Be Published
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8H49
 | | Blasnase-M57P | | 分子名称: | FORMIC ACID, L-asparaginase, MAGNESIUM ION | | 著者 | Lu, F, Wang, W, Chi, H, Ran, T. | | 登録日 | 2022-10-10 | | 公開日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure-based rational design of Bacillus licheniformis L-asparaginase with low/no D-asparaginase activity for a safer enzyme
To Be Published
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8H4A
 | | Blasnase-T13A/M57P | | 分子名称: | FORMIC ACID, L-asparaginase, MAGNESIUM ION | | 著者 | Lu, F, Wang, W, Chi, H, Ran, T. | | 登録日 | 2022-10-10 | | 公開日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-based rational design of Bacillus licheniformis L-asparaginase with low/no D-asparaginase activity for a safer enzyme
To Be Published
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8H4C
 | | Blasnase-T13A/M57P | | 分子名称: | FORMIC ACID, L-asparaginase, MAGNESIUM ION | | 著者 | Lu, F, Wang, W, Chi, H, Ran, T. | | 登録日 | 2022-10-10 | | 公開日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure-based rational design of Bacillus licheniformis L-asparaginase with low/no D-asparaginase activity for a safer enzyme
To Be Published
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8H4G
 | | Blasnase-T13A/M57N | | 分子名称: | FORMIC ACID, L-asparaginase, MAGNESIUM ION | | 著者 | Lu, F, Wang, W, Chi, H, Ran, T. | | 登録日 | 2022-10-10 | | 公開日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Structure-based rational design of Bacillus licheniformis L-asparaginase with low/no D-asparaginase activity for a safer enzyme
To Be Published
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8H4F
 | | Blasnase-T13A/P55F with D-asn | | 分子名称: | D-ASPARAGINE, FORMIC ACID, L-asparaginase, ... | | 著者 | Lu, F, Wang, W, Chi, H, Ran, T. | | 登録日 | 2022-10-10 | | 公開日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-based rational design of Bacillus licheniformis L-asparaginase with low/no D-asparaginase activity for a safer enzyme
To Be Published
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8GQR
 | | Crystal structure of VioD with FAD | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, SULFATE ION, ... | | 著者 | Ran, T, Wang, W, Xu, M. | | 登録日 | 2022-08-30 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for substrate binding and catalytic mechanism of the key enzyme VioD in the violacein synthesis pathway.
Proteins, 91, 2023
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7E58
 | | interferon-inducible anti-viral protein 2 | | 分子名称: | Guanylate-binding protein 2 | | 著者 | Cui, W, Wang, W, Chen, C, Slater, B, Xiong, Y, Ji, X.Y, Yang, H.T. | | 登録日 | 2021-02-18 | | 公開日 | 2021-05-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7E59
 | | interferon-inducible anti-viral protein truncated | | 分子名称: | Guanylate-binding protein 5 | | 著者 | Cui, W, Wang, W, Chen, C, Slater, B, Xiong, Y, Ji, X.Y, Yang, H.T. | | 登録日 | 2021-02-18 | | 公開日 | 2021-05-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
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8H4E
 | | Blasnase-T13A/P55N with D-asn | | 分子名称: | D-ASPARAGINE, FORMIC ACID, L-asparaginase, ... | | 著者 | Lu, F, Wang, W, Chi, H, Ran, T. | | 登録日 | 2022-10-10 | | 公開日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Structure-based rational design of Bacillus licheniformis L-asparaginase with low/no D-asparaginase activity for a safer enzyme
To Be Published
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7K0V
 | | Crystal structure of bRaf in complex with inhibitor GNE-0749 | | 分子名称: | CHLORIDE ION, N-(3,3-dimethylbutyl)-N'-{2-fluoro-5-[(5-fluoro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]-4-methylphenyl}urea, Non-specific serine/threonine protein kinase | | 著者 | Yin, J, Eigenbrot, C.E, Wang, W. | | 登録日 | 2020-09-06 | | 公開日 | 2021-05-26 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a 5-Fluoro-4-(3 H )-quinazolinone Aryl Urea pan-RAF Kinase Inhibitor.
J.Med.Chem., 64, 2021
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4O0Y
 | | Back pocket flexibility provides group-II PAK selectivity for type 1 kinase inhibitors | | 分子名称: | 4-[1-(4-amino-1,3,5-triazin-2-yl)-2-(ethylamino)-1H-benzimidazol-6-yl]-2-methylbut-3-yn-2-ol, Serine/threonine-protein kinase PAK 4 | | 著者 | Rouge, L, Tam, C, Wang, W. | | 登録日 | 2013-12-14 | | 公開日 | 2014-02-12 | | 最終更新日 | 2014-02-26 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Back Pocket Flexibility Provides Group II p21-Activated Kinase (PAK) Selectivity for Type I 1/2 Kinase Inhibitors.
J.Med.Chem., 57, 2014
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4O19
 | | The crystal structure of a mutant NAMPT (G217V) | | 分子名称: | 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION | | 著者 | Oh, A, Coons, M, Brillantes, B, Wang, W. | | 登録日 | 2013-12-15 | | 公開日 | 2014-10-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors.
Plos One, 9, 2014
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