7WTF
| SARS-CoV-2 Omicron variant spike in complex with Fab XGv051 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of XGv051, ... | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-02-04 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Selection and structural bases of potent broadly neutralizing antibodies from 3-dose vaccinees that are highly effective against diverse SARS-CoV-2 variants, including Omicron sublineages. Cell Res., 32, 2022
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3RT3
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7WTJ
| SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv286 | Descriptor: | Heavy chain of XGv286, Light chain of XGv286, Spike protein S1 | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-02-04 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Selection and structural bases of potent broadly neutralizing antibodies from 3-dose vaccinees that are highly effective against diverse SARS-CoV-2 variants, including Omicron sublineages. Cell Res., 32, 2022
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7WTG
| SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv051 | Descriptor: | Heavy chain of XGv051, Light chain of XGv051, Spike protein S1 | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-02-04 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Selection and structural bases of potent broadly neutralizing antibodies from 3-dose vaccinees that are highly effective against diverse SARS-CoV-2 variants, including Omicron sublineages. Cell Res., 32, 2022
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7WTH
| SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv264 | Descriptor: | Heavy chain of XGv264, Light chain of XGv264, Spike protein S1 | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-02-04 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Selection and structural bases of potent broadly neutralizing antibodies from 3-dose vaccinees that are highly effective against diverse SARS-CoV-2 variants, including Omicron sublineages. Cell Res., 32, 2022
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7CWU
| SARS-CoV-2 spike proteins trimer in complex with P17 and FC05 Fabs cocktail | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Wang, X, Wang, N. | Deposit date: | 2020-08-31 | Release date: | 2020-12-16 | Last modified: | 2021-01-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure-based development of human antibody cocktails against SARS-CoV-2. Cell Res., 31, 2021
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7FCD
| Structure of the SARS-CoV-2 A372T spike glycoprotein (open) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Wang, X, Zhang, S. | Deposit date: | 2021-07-14 | Release date: | 2022-01-26 | Last modified: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Loss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2. Cell Res., 32, 2022
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7FCE
| Structure of the SARS-CoV-2 A372T spike glycoprotein (closed) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Wang, X, Zhang, S. | Deposit date: | 2021-07-14 | Release date: | 2022-01-26 | Last modified: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Loss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2. Cell Res., 32, 2022
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2GMG
| Solution NMR Structure of protein PF0610 from Pyrococcus furiosus, Northeast Structural Genomics Consortium Target PfG3 | Descriptor: | hypothetical protein Pf0610 | Authors: | Wang, X, Lee, H.S, Adams, M.W, Northeast Structural Genomics Consortium (NESG), Montelione, G.T, Prestegard, J.H. | Deposit date: | 2006-04-06 | Release date: | 2006-11-28 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | PF0610, a novel winged helix-turn-helix variant possessing a rubredoxin-like Zn ribbon motif from the hyperthermophilic archaeon, Pyrococcus furiosus. Biochemistry, 46, 2007
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8WPE
| Structure of monkeypox virus polymerase complex F8-A22-E4-H5 (tag-free A22) with exogenous DNA | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, A22R DNA polymerase processivity factor, DNA polymerase, ... | Authors: | Wang, X, Li, N, Gao, N. | Deposit date: | 2023-10-10 | Release date: | 2023-11-29 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5. Mol.Cell, 83, 2023
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7WT9
| SARS-CoV-2 Omicron variant spike RBD in complex with Fab 9A8 | Descriptor: | Heavy chain of Fab 9A8, Light chain of Fab 9A8, Spike glycoprotein | Authors: | Wang, X, Wang, L. | Deposit date: | 2022-02-04 | Release date: | 2023-06-07 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | A broader neutralizing antibody against all the current VOCs and VOIs targets unique epitope of SARS-CoV-2 RBD. Cell Discov, 8, 2022
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8GX9
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8I3W
| BANAL-20-236 Spike trimer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Wang, X, Xu, G. | Deposit date: | 2023-01-18 | Release date: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | The selective effect of fecal-oral transmission on the S proteins of bat SARS-CoV-2 related coronaviruses in favor of stability over infectivity To Be Published
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7YBI
| SARS-CoV-2 Mu variant spike (open state) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-06-29 | Release date: | 2023-07-12 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structures of SARS-CoV-2 spike protein alert noteworthy sites for the potential approaching variants. Virol Sin, 37, 2022
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7YBL
| SARS-CoV-2 B.1.620 variant spike (close state) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-06-29 | Release date: | 2023-08-09 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of SARS-CoV-2 spike protein alert noteworthy sites for the potential approaching variants. Virol Sin, 37, 2022
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7YBH
| SARS-CoV-2 lambda variant spike | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-06-29 | Release date: | 2023-08-09 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structures of SARS-CoV-2 spike protein alert noteworthy sites for the potential approaching variants. Virol Sin, 37, 2022
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7YBM
| SARS-CoV-2 C.1.2 variant spike (Close state) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-06-29 | Release date: | 2023-08-09 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Structures of SARS-CoV-2 spike protein alert noteworthy sites for the potential approaching variants. Virol Sin, 37, 2022
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7YBK
| SARS-CoV-2 B.1.620 variant spike (open state) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-06-29 | Release date: | 2023-09-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structures of SARS-CoV-2 spike protein alert noteworthy sites for the potential approaching variants. Virol Sin, 37, 2022
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6LW2
| The N-arylsulfonyl-indole-2-carboxamide-based inhibitors against fructose-1,6-bisphosphatase | Descriptor: | 7-chloranyl-4-[(3-methoxyphenyl)amino]-N-(4-methoxyphenyl)sulfonyl-1-methyl-indole-2-carboxamide, Fructose-1,6-bisphosphatase 1 | Authors: | Wang, X.Y, Zhou, J, Xu, B.L. | Deposit date: | 2020-02-07 | Release date: | 2020-05-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Discovery of N -Arylsulfonyl-Indole-2-Carboxamide Derivatives as Potent, Selective, and Orally Bioavailable Fructose-1,6-Bisphosphatase Inhibitors-Design, Synthesis, In Vivo Glucose Lowering Effects, and X-ray Crystal Complex Analysis. J.Med.Chem., 63, 2020
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8WPF
| Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with exogenous DNA bearing one abasic site | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, A22R DNA polymerase processivity factor, DNA polymerase, ... | Authors: | Wang, X, Li, N, Gao, N. | Deposit date: | 2023-10-10 | Release date: | 2023-11-29 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5. Mol.Cell, 83, 2023
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8WPK
| Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with exgenous DNA | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA polymerase, DNA polymerase processivity factor, ... | Authors: | Wang, X, Li, N, Gao, N. | Deposit date: | 2023-10-10 | Release date: | 2023-11-29 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5. Mol.Cell, 83, 2023
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8WPP
| Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with endogenous DNA | Descriptor: | A22R DNA polymerase processivity factor, DNA polymerase, E4R Uracil-DNA glycosylase, ... | Authors: | Wang, X, Li, N, Gao, N. | Deposit date: | 2023-10-10 | Release date: | 2023-11-29 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5. Mol.Cell, 83, 2023
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4EGT
| Crystal structure of major capsid protein P domain from rabbit hemorrhagic disease virus | Descriptor: | Major capsid protein VP60 | Authors: | Wang, X, Xu, F, Zhang, K, Zhai, Y, Sun, F. | Deposit date: | 2012-04-01 | Release date: | 2013-01-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Atomic model of rabbit hemorrhagic disease virus by cryo-electron microscopy and crystallography. Plos Pathog., 9, 2013
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6AJC
| Crystal structure of Trypanosoma cruzi cytosolic isocitrate dehydrogenase in complex with NADP+, isocitrate and ca2+ | Descriptor: | CALCIUM ION, ISOCITRIC ACID, Isocitrate dehydrogenase [NADP], ... | Authors: | Wang, X, Inaoka, D.K, Shiba, T, Balogun, E.O, Ziebart, N, Allman, S, Watanabe, Y, Nozaki, T, Boshart, M, Bringaud, F, Harada, S, Kita, K. | Deposit date: | 2018-08-27 | Release date: | 2019-08-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Biochemical characterization of a novel Trypanosoma brucei glycosomal isocitrate dehydrogenase with dual coenzyme specificity (NADP+/NAD+) To Be Published
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7YBJ
| SARS-CoV-2 Mu variant spike(close state) | Descriptor: | Spike glycoprotein | Authors: | Wang, X, Fu, W. | Deposit date: | 2022-06-29 | Release date: | 2023-07-12 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.73 Å) | Cite: | Structures of SARS-CoV-2 spike protein alert noteworthy sites for the potential approaching variants. Virol Sin, 37, 2022
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