6U1Q
 
 | | Crystal Structure of VpsO (VC0937) Kinase domain | | 分子名称: | O-PHOSPHOTYROSINE, VpsO | | 著者 | Tripathi, S.M, Schwechheimer, C, Herbert, K, Porcella, M.E, Brown, E.R, Yildiz, F.H, Rubin, S.M. | | 登録日 | 2019-08-16 | | 公開日 | 2020-08-19 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | | 主引用文献 | A tyrosine phosphoregulatory system controls exopolysaccharide biosynthesis and biofilm formation in Vibrio cholerae.
Plos Pathog., 16, 2020
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6U1P
 | | Crystal structure of VpsU (VC0916) from Vibrio cholerae | | 分子名称: | GLYCEROL, Low molecular weight phosphotyrosine protein phosphatase | | 著者 | Tripathi, S.M, Schwechheimer, C, Herbert, K, Osorio, J, Yildiz, F.H, Rubin, S.M. | | 登録日 | 2019-08-16 | | 公開日 | 2020-08-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | A tyrosine phosphoregulatory system controls exopolysaccharide biosynthesis and biofilm formation in Vibrio cholerae.
Plos Pathog., 16, 2020
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8CUR
 | | Crystal structure of Cdk2 in complex with Cyclin A inhibitor 6-[(E)-2-(4-chlorophenyl)ethenyl]-2-{[(2R)-3-(4-hydroxyphenyl)-1-methoxy-1-oxopropan-2-yl]carbamoyl}quinoline-4-carboxylic acid | | 分子名称: | 6-[(E)-2-(4-chlorophenyl)ethenyl]-2-{[(2R)-3-(4-hydroxyphenyl)-1-methoxy-1-oxopropan-2-yl]carbamoyl}quinoline-4-carboxylic acid, Cyclin-dependent kinase 2 | | 著者 | Tripathi, S.M, Tambo, C.S, Kiss, G, Rubin, S.M. | | 登録日 | 2022-05-17 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Biolayer Interferometry Assay for Cyclin-Dependent Kinase-Cyclin Association Reveals Diverse Effects of Cdk2 Inhibitors on Cyclin Binding Kinetics.
Acs Chem.Biol., 18, 2023
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2VOJ
 | | Ternary complex of M. tuberculosis Rv2780 with NAD and pyruvate | | 分子名称: | (2S)-2-HYDROXYPROPANOIC ACID, ALANINE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Tripathi, S.M, Ramachandran, R. | | 登録日 | 2008-02-18 | | 公開日 | 2008-03-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structures of the Mycobacterium Tuberculosis Secretory Antigen Alanine Dehydrogenase (Rv2780) in Apo and Ternary Complex Forms Captures "Open" and "Closed" Enzyme Conformations.
Proteins: Struct., Funct., Bioinf., 72, 2008
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2VOE
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2CIN
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2CJH
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2CJD
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2CJG
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2JJF
 | | N328A mutant of M. tuberculosis Rv3290c | | 分子名称: | L-LYSINE EPSILON AMINOTRANSFERASE | | 著者 | tripathi, S.M, Ramachandran, R. | | 登録日 | 2008-04-04 | | 公開日 | 2009-06-30 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Mutational Analysis of Mycobacterium Tuberculosis Lysine Epsilon-Aminotransferase and Inhibitor Co-Crystal Structures, Reveals Distinct Binding Modes.
Biochem.Biophys.Res.Commun., 463, 2015
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2JJH
 | | E243 mutant of M. tuberculosis Rv3290C | | 分子名称: | 2-OXOGLUTARIC ACID, L-LYSINE EPSILON AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Tripathi, S.M, Ramachandran, R. | | 登録日 | 2008-04-04 | | 公開日 | 2009-06-30 | | 最終更新日 | 2020-01-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Mutational Analysis of Mycobacterium Tuberculosis Lysine Epsilon-Aminotransferase and Inhibitor Co-Crystal Structures, Reveals Distinct Binding Modes.
Biochem.Biophys.Res.Commun., 463, 2015
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2JJG
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2JJE
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4IMH
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4JWU
 | | Crystal structure of Cytochrome P450cam-putidaredoxin complex | | 分子名称: | 1,1'-hexane-1,6-diyldipyrrolidine-2,5-dione, CALCIUM ION, Camphor 5-monooxygenase, ... | | 著者 | Tripathi, S.M, Li, H, Poulos, T.L. | | 登録日 | 2013-03-27 | | 公開日 | 2013-06-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for effector control and redox partner recognition in cytochrome P450.
Science, 340, 2013
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4JWS
 | | Crystal structure of Cytochrome P450cam-putidaredoxin complex | | 分子名称: | 1,1'-hexane-1,6-diyldipyrrolidine-2,5-dione, CALCIUM ION, Camphor 5-monooxygenase, ... | | 著者 | Tripathi, S.M, Li, H, Poulos, T.L. | | 登録日 | 2013-03-27 | | 公開日 | 2013-06-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural basis for effector control and redox partner recognition in cytochrome P450.
Science, 340, 2013
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4JX1
 | | Crystal structure of reduced Cytochrome P450cam-putidaredoxin complex bound to camphor and 5-exo-hydroxycamphor | | 分子名称: | 1,1'-hexane-1,6-diyldipyrrolidine-2,5-dione, 5-EXO-HYDROXYCAMPHOR, CALCIUM ION, ... | | 著者 | Tripathi, S.M, Li, H, Poulos, T.L. | | 登録日 | 2013-03-27 | | 公開日 | 2013-06-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.087 Å) | | 主引用文献 | Structural basis for effector control and redox partner recognition in cytochrome P450.
Science, 340, 2013
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6CPB
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6X61
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7N40
 | | Crystal structure of LIN9-RbAp48-LIN37, a MuvB subcomplex | | 分子名称: | Histone-binding protein RBBP4, Isoform 2 of Protein lin-9 homolog, Protein lin-37 homolog | | 著者 | Asthana, A, Ramanan, P, Tripathi, S.M, Rubin, S.M. | | 登録日 | 2021-06-02 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | The MuvB complex binds and stabilizes nucleosomes downstream of the transcription start site of cell-cycle dependent genes.
Nat Commun, 13, 2022
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6P8F
 | | Crystal structure of CDK4 in complex with CyclinD1 and P27 | | 分子名称: | Cyclin-dependent kinase 4, Cyclin-dependent kinase inhibitor 1B, G1/S-specific cyclin-D1 | | 著者 | Guiley, K.Z, Stevenson, J.W, Lou, K, Barkovich, K.J, Bunch, K, Tripathi, S.M, Shokat, K.M, Rubin, S.M. | | 登録日 | 2019-06-07 | | 公開日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition.
Science, 366, 2019
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6P8H
 | | Crystal structure of CDK4 in complex with CyclinD1 and P21 | | 分子名称: | Cyclin-dependent kinase 4, Cyclin-dependent kinase inhibitor 1, G1/S-specific cyclin-D1 | | 著者 | Guiley, K.Z, Stevenson, J.W, Lou, K, Barkovich, K.J, Bunch, K, Tripathi, S.M, Shokat, K.M, Rubin, S.M. | | 登録日 | 2019-06-07 | | 公開日 | 2019-12-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | | 主引用文献 | p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition.
Science, 366, 2019
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6P8G
 | | Crystal structure of CDK4 in complex with CyclinD1 and P27 | | 分子名称: | Cyclin-dependent kinase 4, Cyclin-dependent kinase inhibitor 1B, G1/S-specific cyclin-D1 | | 著者 | Guiley, K.Z, Stevenson, J.W, Lou, K, Barkovich, K.J, Bunch, K, Tripathi, S.M, Shokat, K.M, Rubin, S.M. | | 登録日 | 2019-06-07 | | 公開日 | 2019-12-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition.
Science, 366, 2019
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6P8E
 | | Crystal structure of CDK4 in complex with CyclinD1 and P27 | | 分子名称: | Cyclin-dependent kinase 4, Cyclin-dependent kinase inhibitor 1B, G1/S-specific cyclin-D1, ... | | 著者 | Guiley, K.Z, Stevenson, J.W, Lou, K, Barkovich, K.J, Bunch, K, Tripathi, S.M, Shokat, K.M, Rubin, S.M. | | 登録日 | 2019-06-07 | | 公開日 | 2019-12-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition.
Science, 366, 2019
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6OF7
 | | Crystal structure of the CRY1-PER2 complex | | 分子名称: | Cryptochrome-1, Period circadian protein homolog 2 | | 著者 | Michael, A.K, Fribourgh, J.L, Tripathi, S.M, Partch, C.L. | | 登録日 | 2019-03-28 | | 公開日 | 2020-03-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing.
Elife, 9, 2020
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