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PDB: 315 件

8SKO
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X-ray structure of the NDM-4 beta-lactamase from Klebsiella pneumonia with L-Captopril bound
分子名称: L-CAPTOPRIL, Metallo-beta-lactamase type 2, ZINC ION
著者Thoden, J.B, Holden, H.M.
登録日2023-04-20
公開日2023-08-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Characterization of a novel inhibitor for the New Delhi metallo-beta-lactamase-4: Implications for drug design and combating bacterial drug resistance.
J.Biol.Chem., 299, 2023
4OQD
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Crystal structure of the tylM1 N,N-dimethyltransferase in complex with SAH and TDP-Qui3NMe2
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, TDP-3,6-dideoxy-3-N,N-dimethylglucose, dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase
著者Thoden, J.B, Holden, H.M.
登録日2014-02-08
公開日2014-02-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Production of a novel N-monomethylated dideoxysugar.
Biochemistry, 53, 2014
4ZU5
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Crystal structure of the QdtA 3,4-Ketoisomerase from Thermoanaerobacterium thermosaccharolyticum, apo form
分子名称: (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol, QdtA, THYMIDINE
著者Thoden, J.B, Vinogradov, E, Gilbert, M, Salinger, A.J, Holden, H.M.
登録日2015-05-15
公開日2016-03-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Bacterial Sugar 3,4-Ketoisomerases: Structural Insight into Product Stereochemistry.
Biochemistry, 54, 2015
4ZU7
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X-ray structure if the QdtA 3,4-ketoisomerase from Thermoanaerobacterium thermosaccharolyticum, double mutant Y17R/R97H, in complex with TDP
分子名称: (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol, QdtA, THYMIDINE-5'-DIPHOSPHATE
著者Thoden, J.B, Vinogradov, E, Gilbert, M, Salinger, A.J, Holden, H.M.
登録日2015-05-15
公開日2015-07-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Bacterial Sugar 3,4-Ketoisomerases: Structural Insight into Product Stereochemistry.
Biochemistry, 54, 2015
4ZU4
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X-ray structure of the 3,4-ketoisomerase domain of FdtD from Shewanella denitrificans
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, PHOSPHATE ION, ...
著者Thoden, J.B, Vinogradov, E, Gilbert, M, Salinger, A.J, Holden, H.M.
登録日2015-05-15
公開日2015-07-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Bacterial Sugar 3,4-Ketoisomerases: Structural Insight into Product Stereochemistry.
Biochemistry, 54, 2015
4OQE
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Crystal structure of the tylM1 N,N-dimethyltransferase in complex with SAH and TDP-Fuc3NMe
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, dTDP-3-N-methylamino-3,6-dideoxygalactose, dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase
著者Thoden, J.B, Holden, H.M.
登録日2014-02-08
公開日2014-02-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Production of a novel N-monomethylated dideoxysugar.
Biochemistry, 53, 2014
4O9E
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Crystal structure of QdtA, a sugar 3,4-ketoisemerase from Thermoanaerobacterium thermosaccharolyticum in complex with TDP
分子名称: (2S)-1-[3-[(2S)-2-oxidanylpropoxy]-2-[[(2S)-2-oxidanylpropoxy]methyl]-2-[[(2R)-2-oxidanylpropoxy]methyl]propoxy]propan-2-ol, QdtA, THYMIDINE-5'-DIPHOSPHATE, ...
著者Thoden, J.B, Holden, H.M.
登録日2014-01-02
公開日2014-04-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The molecular architecture of QdtA, a sugar 3,4-ketoisomerase from Thermoanaerobacterium thermosaccharolyticum.
Protein Sci., 23, 2014
4O9G
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Crystal structure of the H51N mutant of the 3,4-ketoisomerase QdtA from Thermoanaerobacterium thermosaccharolyticum in complex with TDP-4-keto-6-deoxyglucose
分子名称: (2S)-1-[3-[(2S)-2-oxidanylpropoxy]-2-[[(2S)-2-oxidanylpropoxy]methyl]-2-[[(2R)-2-oxidanylpropoxy]methyl]propoxy]propan-2-ol, 1,2-ETHANEDIOL, QdtA, ...
著者Thoden, J.B, Holden, H.M.
登録日2014-01-02
公開日2014-04-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The molecular architecture of QdtA, a sugar 3,4-ketoisomerase from Thermoanaerobacterium thermosaccharolyticum.
Protein Sci., 23, 2014
5BSZ
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X-ray structure of the sugar N-methyltransferase KedS8 from Streptoalloteichus sp ATCC 53650
分子名称: 1,2-ETHANEDIOL, N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Thoden, J.B, Delvaux, N.A, Holden, H.M.
登録日2015-06-02
公開日2015-07-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular architecture of KedS8, a sugar N-methyltransferase from Streptoalloteichus sp. ATCC 53650.
Protein Sci., 24, 2015
4NV1
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Crystal structure of a 4-N formyltransferase from Francisella tularensis
分子名称: Formyltransferase, PHOSPHATE ION, THYMIDINE-5'-DIPHOSPHATE, ...
著者Thoden, J.B, Zimmer, A.L, Holden, H.M.
登録日2013-12-04
公開日2013-12-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Three-dimensional structure of a sugar N-formyltransferase from Francisella tularensis.
Protein Sci., 23, 2014
4EA7
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X-ray crystal structure of PerB from Caulobacter crescentus in complex with CoA and GDP-perosamine at 1.0 Angstrom resolution
分子名称: CHLORIDE ION, COENZYME A, GDP-perosamine, ...
著者Thoden, J.B, Reinhardt, L.A, Cook, P.D, Menden, P, Cleland, W.W, Holden, H.M.
登録日2012-03-22
公開日2012-04-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Catalytic Mechanism of Perosamine N-Acetyltransferase Revealed by High-Resolution X-ray Crystallographic Studies and Kinetic Analyses.
Biochemistry, 51, 2012
4EA8
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X-ray crystal structure of PerB from Caulobacter crescentus in complex with coenzyme A and GDP-N-acetylperosamine at 1 Angstrom resolution
分子名称: CHLORIDE ION, COENZYME A, GDP-N-acetylperosamine, ...
著者Thoden, J.B, Reinhardt, L.A, Cook, P.D, Menden, P, Cleland, W.W, Holden, H.M.
登録日2012-03-22
公開日2012-04-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Catalytic Mechanism of Perosamine N-Acetyltransferase Revealed by High-Resolution X-ray Crystallographic Studies and Kinetic Analyses.
Biochemistry, 51, 2012
4EAA
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BU of 4eaa by Molmil
X-ray crystal structure of the H141N mutant of perosamine N-acetyltransferase from Caulobacter crescentus in complex with CoA and GDP-perosamine
分子名称: CHLORIDE ION, COENZYME A, GDP-perosamine, ...
著者Thoden, J.B, Reinhardt, L.A, Cook, P.D, Menden, P, Cleland, W.W, Holden, H.M.
登録日2012-03-22
公開日2012-04-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Catalytic Mechanism of Perosamine N-Acetyltransferase Revealed by High-Resolution X-ray Crystallographic Studies and Kinetic Analyses.
Biochemistry, 51, 2012
4EAB
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X-ray crystal structure of the H141A mutant of GDP-perosamine N-acetyl transferase from Caulobacter crescentus in complex with CoA and GDP-perosamine
分子名称: CHLORIDE ION, COENZYME A, GDP-perosamine, ...
著者Thoden, J.B, Reinhardt, L.A, Cook, P.D, Menden, P, Cleland, W.W, Holden, H.M.
登録日2012-03-22
公開日2012-04-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Catalytic Mechanism of Perosamine N-Acetyltransferase Revealed by High-Resolution X-ray Crystallographic Studies and Kinetic Analyses.
Biochemistry, 51, 2012
4EA9
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X-ray structure of GDP-perosamine N-acetyltransferase in complex with transition state analog at 0.9 Angstrom resolution
分子名称: CHLORIDE ION, GDP-N-acetylperosamine-coenzyme A, Perosamine N-acetyltransferase
著者Thoden, J.B, Reinhardt, L.A, Cook, P.D, Menden, P, Cleland, W.W, Holden, H.M.
登録日2012-03-22
公開日2012-04-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献Catalytic Mechanism of Perosamine N-Acetyltransferase Revealed by High-Resolution X-ray Crystallographic Studies and Kinetic Analyses.
Biochemistry, 51, 2012
3E1K
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Crystal structure of Kluyveromyces lactis Gal80p in complex with the acidic activation domain of Gal4p
分子名称: Galactose/lactose metabolism regulatory protein GAL80, Lactose regulatory protein LAC9
著者Thoden, J.B, Holden, H.M.
登録日2008-08-04
公開日2008-08-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Interaction between an Acidic Transcriptional Activator and Its Inhibitor: THE MOLECULAR BASIS OF Gal4p RECOGNITION BY Gal80p.
J.Biol.Chem., 283, 2008
3FRK
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X-ray structure of QdtB from T. thermosaccharolyticum in complex with a PLP:TDP-3-aminoquinovose aldimine
分子名称: (2R,3R,4S,5S,6R)-3,5-dihydroxy-4-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate, QdtB
著者Thoden, J.B, Holden, H.M.
登録日2009-01-08
公開日2009-02-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural analysis of QdtB, an aminotransferase required for the biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose.
Biochemistry, 48, 2009
4LXX
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Crystal structure WlaRD, a sugar 3N-formyl transferase in the presence of dTDP-Fuc3NFo and 5-N-Formyl-THF
分子名称: (2R,3R,4S,5R,6R)-4-(formylamino)-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name), 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ...
著者thoden, J.B, goneau, M.-F, gilbert, M, holden, H.M.
登録日2013-07-30
公開日2013-08-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure of a sugar N-formyltransferase from Campylobacter jejuni.
Biochemistry, 52, 2013
4LXY
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Crystal structure WlaRD, a sugar 3N-formyl transferase in the presence of dTDP and 10-N-Formyl-THF
分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, N-{4-[{[(6S)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}(formyl)amino]benzoyl}-L-glutamic acid, THYMIDINE-5'-DIPHOSPHATE, ...
著者Thoden, J.B, Goneau, M.-F, Gilbert, M, Holden, H.M.
登録日2013-07-30
公開日2013-08-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structure of a sugar N-formyltransferase from Campylobacter jejuni.
Biochemistry, 52, 2013
4LXU
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dTdp-Fuc3N and 5-N-Formyl-THF
分子名称: (3R,4S,5R,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl][hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate, 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ...
著者Thoden, J.B, Goneau, M.-F, Gilbert, M, Holden, H.M.
登録日2013-07-30
公開日2013-08-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure of a sugar N-formyltransferase from Campylobacter jejuni.
Biochemistry, 52, 2013
4LXQ
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Crystal structure WlaRD, a sugar 3N-formyl transferase in the presence of dTdp and 5-N-Formyl-THF
分子名称: 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ...
著者Thoden, J.B, Goneau, M.-F, Gilbert, M, Holden, H.M.
登録日2013-07-30
公開日2013-08-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure of a sugar N-formyltransferase from Campylobacter jejuni.
Biochemistry, 52, 2013
4LY3
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Crystal structure of WlaRD, a sugar 3N-formyl transferase in the presence of dTPD-Qui3N, dTDP-Qui3NFo, and THF
分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, N-[4-({[(6R)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, WlaRD a sugar 3N formyltransferase, ...
著者Thoden, J.B, Goneau, M.-F, Gilbert, M, Holden, H.M.
登録日2013-07-30
公開日2013-08-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of a sugar N-formyltransferase from Campylobacter jejuni.
Biochemistry, 52, 2013
4LXT
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Crystal structure WlaRD, a sugar 3N-formyl transferase in the presence of dTdp-Qui3N and 5-N-Formyl-THF
分子名称: 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ...
著者Thoden, J.B, Goneau, M.-F, Gilbert, M, Holden, H.M.
登録日2013-07-30
公開日2013-08-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure of a sugar N-formyltransferase from Campylobacter jejuni.
Biochemistry, 52, 2013
1ONX
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BU of 1onx by Molmil
Crystal structure of isoaspartyl dipeptidase from escherichia coli complexed with aspartate
分子名称: ASPARTIC ACID, Isoaspartyl dipeptidase, ZINC ION
著者Thoden, J.B, Marti-Arbona, R, Raushel, F.M, Holden, H.M.
登録日2003-03-02
公開日2003-05-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献High Resolution X-ray Structure of Isoaspartyl Dipeptidase from Escherichia coli
Biochemistry, 42, 2003
1NAH
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UDP-GALACTOSE 4-EPIMERASE FROM ESCHERICHIA COLI, REDUCED
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Thoden, J.B, Frey, P.A, Holden, H.M.
登録日1995-11-22
公開日1996-12-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of the oxidized and reduced forms of UDP-galactose 4-epimerase isolated from Escherichia coli.
Biochemistry, 35, 1996

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