6PS4
| XFEL beta2 AR structure by ligand exchange from Timolol to ICI-118551. | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]butan-2-ol, CHOLESTEROL, ... | 著者 | Ishchenko, A, Stauch, B, Han, G.W, Batyuk, A, Shiriaeva, A, Li, C, Zatsepin, N.A, Weierstall, U, Liu, W, Nango, E, Nakane, T, Tanaka, R, Tono, K, Joti, Y, Iwata, S, Moraes, I, Gati, C, Cherezov, C. | 登録日 | 2019-07-12 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Toward G protein-coupled receptor structure-based drug design using X-ray lasers. Iucrj, 6, 2019
|
|
6PS8
| XFEL MT1R structure by ligand exchange from agomelatine to 2-phenylmelatonin. | 分子名称: | Fusion protein of Melatonin receptor type 1A and GlgA glycogen synthase, N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]acetamide | 著者 | Ishchenko, A, Stauch, B, Han, G.W, Batyuk, A, Shiriaeva, A, Li, C, Zatsepin, N.A, Weierstall, U, Liu, W, Nango, E, Nakane, T, Tanaka, R, Tono, K, Joti, Y, Iwata, S, Moraes, I, Gati, C, Cherezov, C. | 登録日 | 2019-07-12 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Toward G protein-coupled receptor structure-based drug design using X-ray lasers. Iucrj, 6, 2019
|
|
6PS5
| XFEL beta2 AR structure by ligand exchange from Timolol to Propranolol. | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1-(ISOPROPYLAMINO)-3-(1-NAPHTHYLOXY)-2-PROPANOL, CHOLESTEROL, ... | 著者 | Ishchenko, A, Stauch, B, Han, G.W, Batyuk, A, Shiriaeva, A, Li, C, Zatsepin, N.A, Weierstall, U, Liu, W, Nango, E, Nakane, T, Tanaka, R, Tono, K, Joti, Y, Iwata, S, Moraes, I, Gati, C, Cherezov, C. | 登録日 | 2019-07-12 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Toward G protein-coupled receptor structure-based drug design using X-ray lasers. Iucrj, 6, 2019
|
|
6PS2
| XFEL beta2 AR structure by ligand exchange from Timolol to Alprenolol. | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-1-[(1-methylethyl)amino]-3-(2-prop-2-en-1-ylphenoxy)propan-2-ol, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ... | 著者 | Ishchenko, A, Stauch, B, Han, G.W, Batyuk, A, Shiriaeva, A, Li, C, Zatsepin, N.A, Weierstall, U, Liu, W, Nango, E, Nakane, T, Tanaka, R, Tono, K, Joti, Y, Iwata, S, Moraes, I, Gati, C, Cherezov, C. | 登録日 | 2019-07-12 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Toward G protein-coupled receptor structure-based drug design using X-ray lasers. Iucrj, 6, 2019
|
|
5IYS
| Crystal structure of a dehydrosqualene synthase in complex with ligand | 分子名称: | MAGNESIUM ION, Phytoene synthase, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, ... | 著者 | Liu, G.Z, Liu, W.D, Chen, C.C, Guo, R.T. | 登録日 | 2016-03-24 | 公開日 | 2017-03-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Crystal structure of a dehydrosqualene synthase in complex with ligand to be published
|
|
5XO8
| Crystal structure of a novel ZEN lactonase mutant with ligand Z | 分子名称: | (3S,11E)-14,16-dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione, Lactonase for protein | 著者 | Zheng, Y.Y, Liu, W.T, Liu, W.D, Chen, C.C, Guo, R.T. | 登録日 | 2017-05-27 | 公開日 | 2018-05-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Crystal Structure of a Mycoestrogen-Detoxifying Lactonase from Rhinocladiella mackenziei: Molecular Insight into ZHD Substrate Selectivity Acs Catalysis, 8, 2018
|
|
5XO7
| Crystal structure of a novel ZEN lactonase mutant with ligand a | 分子名称: | (3S,7R,11E)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-1-one, lactonase for protein | 著者 | Zheng, Y.Y, Liu, W.T, Liu, W.D, Chen, C.C, Guo, R.T. | 登録日 | 2017-05-27 | 公開日 | 2018-05-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Crystal Structure of a Mycoestrogen-Detoxifying Lactonase from Rhinocladiella mackenziei: Molecular Insight into ZHD Substrate Selectivity Acs Catalysis, 8, 2018
|
|
7JPZ
| Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI1 | 分子名称: | (phenylmethyl) N-[(2S)-1-oxidanylidene-1-[[(2S)-1-oxidanyl-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-3-phenyl-propan-2-yl]carbamate, 3C-like proteinase | 著者 | Yang, K, Liu, W. | 登録日 | 2020-08-10 | 公開日 | 2020-12-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*. Chemmedchem, 16, 2021
|
|
7JQ5
| |
7JQ3
| |
7JPY
| |
7JQ4
| |
7JQ0
| |
7JQ1
| |
7JQ2
| |
5I77
| Crystal structure of a beta-1,4-endoglucanase from Aspergillus niger | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Li, Y.J, Liu, W.D, Zheng, Y.Y, Chen, C.C, Guo, R.T. | 登録日 | 2016-02-17 | 公開日 | 2016-12-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Functional and structural analysis of Pichia pastoris-expressed Aspergillus niger 1,4-beta-endoglucanase Biochem. Biophys. Res. Commun., 475, 2016
|
|
5GSV
| Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide 142-5 | 分子名称: | 10-mer peptide from Spike protein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | 著者 | Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F. | 登録日 | 2016-08-17 | 公開日 | 2017-04-26 | 実験手法 | X-RAY DIFFRACTION (1.996 Å) | 主引用文献 | Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC. J. Immunol., 198, 2017
|
|
5XWZ
| Crystal structure of a lactonase from Cladophialophora bantiana | 分子名称: | GLYCEROL, MALONATE ION, SODIUM ION, ... | 著者 | Zheng, Y.Y, Liu, W.T, Liu, W.D, Chen, C.C, Guo, R.T. | 登録日 | 2017-06-30 | 公開日 | 2018-05-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Characterization and crystal structure of a novel zearalenone hydrolase from Cladophialophora bantiana Acta Crystallogr F Struct Biol Commun, 73, 2017
|
|
5GR7
| Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide 37-1 | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-D alpha chain, ... | 著者 | Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F. | 登録日 | 2016-08-08 | 公開日 | 2017-06-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC. J. Immunol., 198, 2017
|
|
2VLC
| Crystal structure of Natural Cinnamomin (Isoform III) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ribosome-inactivating protein, beta-D-mannopyranose, ... | 著者 | Azzi, A, Wang, T, Zhu, D.-W, Zou, Y.-S, Liu, W.-Y, Lin, S.-X. | 登録日 | 2008-01-11 | 公開日 | 2009-02-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Crystal Structure of Native Cinnamomin Isoform III and its Comparison with Other Ribosome Inactivating Proteins. Proteins: Struct., Funct., Bioinf., 74, 2009
|
|
5GSB
| Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide 37-3 | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-D alpha chain, ... | 著者 | Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F. | 登録日 | 2016-08-15 | 公開日 | 2017-07-12 | 最終更新日 | 2017-10-04 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC. J. Immunol., 198, 2017
|
|
5XO6
| Crystal structure of a novel ZEN lactonase mutant | 分子名称: | PENTAETHYLENE GLYCOL, lactonase for protein | 著者 | Zheng, Y.Y, Liu, W.T, Liu, W.D, Chen, C.C, Guo, R.T. | 登録日 | 2017-05-27 | 公開日 | 2018-05-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Crystal Structure of a Mycoestrogen-Detoxifying Lactonase from Rhinocladiella mackenziei: Molecular Insight into ZHD Substrate Selectivity Acs Catalysis, 8, 2018
|
|
1Z3Z
| The crystal structure of a DGD mutant: Q52A | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, POTASSIUM ION, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Fogle, E.J, Liu, W, Toney, M.D. | 登録日 | 2005-03-14 | 公開日 | 2006-01-03 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Role of q52 in catalysis of decarboxylation and transamination in dialkylglycine decarboxylase. Biochemistry, 44, 2005
|
|
1ZC9
| The crystal structure of dialkylglycine decarboxylase complex with pyridoxamine 5-phosphate | 分子名称: | 2,2-dialkylglycine decarboxylase, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, POTASSIUM ION, ... | 著者 | Fogle, E.J, Liu, W, Toney, M.D. | 登録日 | 2005-04-11 | 公開日 | 2006-01-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Role of q52 in catalysis of decarboxylation and transamination in dialkylglycine decarboxylase. Biochemistry, 44, 2005
|
|
6WQA
| 2.0A angstrom A2a adenosine receptor structure using XFEL data collected in helium atmosphere. | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, ... | 著者 | Lee, M.-Y, Geiger, J, Ishchenko, A, Han, G.W, Barty, A, White, T.A, Gati, C, Batyuk, A, Hunter, M.S, Aquila, A, Boutet, S, Weierstall, U, Cherezov, V, Liu, W. | 登録日 | 2020-04-28 | 公開日 | 2020-11-18 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Harnessing the power of an X-ray laser for serial crystallography of membrane proteins crystallized in lipidic cubic phase Iucrj, 7, 2020
|
|