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PDB: 765 件

7D1G
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Crystal structure of Glyceraldehyde-3-Phosphate Dehydrogenase GAPDH from Clostridium beijerinckii
分子名称: BETA-MERCAPTOETHANOL, Glyceraldehyde-3-phosphate dehydrogenase, MAGNESIUM ION
著者Chen, Y, Lan, J, Liu, W, Wang, L, Xu, Y.
登録日2020-09-14
公開日2021-03-17
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Crystal structure of Glyceraldehyde-3-Phosphate Dehydrogenase GAPDH from Clostridium beijerinckii
To Be Published
7CUN
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BU of 7cun by Molmil
The structure of human Integrator-PP2A complex
分子名称: Integrator complex subunit 1, Integrator complex subunit 11, Integrator complex subunit 2, ...
著者Zheng, H, Qi, Y, Liu, W, Li, J, Wang, J, Xu, Y.
登録日2020-08-23
公開日2020-11-25
最終更新日2020-12-09
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase.
Science, 370, 2020
7FBP
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BU of 7fbp by Molmil
FXIIa-cMCoFx1 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor XIIa light chain, cMCoFx1
著者Sengoku, T, Liu, W, de Veer, S.J, Huang, Y.H, Okada, C, Zdenek, C.N, Fry, B.G, Swedberg, J.E, Passioura, T, Craik, D.J, Suga, H, Ogata, K.
登録日2021-07-12
公開日2021-11-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献An Ultrapotent and Selective Cyclic Peptide Inhibitor of Human beta-Factor XIIa in a Cyclotide Scaffold.
J.Am.Chem.Soc., 143, 2021
7Y9G
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BU of 7y9g by Molmil
Crystal structure of diterpene synthase VenA from Streptomyces venezuelae ATCC 15439 in complex with pyrophosphate
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ...
著者Zhang, L.L, Xie, Z.Z, Huang, J.-W, Hu, Y.C, Liu, W.D, Yang, Y, Chen, C.-C, Guo, R.-T.
登録日2022-06-24
公開日2023-06-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Molecular insights into the catalytic promiscuity of a bacterial diterpene synthase.
Nat Commun, 14, 2023
6CDT
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Structure of Human Anaplastic Lymphoma Kinase Domain
分子名称: ALK tyrosine kinase receptor
著者McTigue, M, Deng, Y.L, Liu, W, Brooun, A.
登録日2018-02-09
公開日2019-02-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Reviving B-Factors: Activating ALK Mutations Increase Protein Dynamics of the Unphosphorylated Kinase.
ACS Med Chem Lett, 9, 2018
7JP0
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Crystal structure of Mpro with inhibitor r1
分子名称: 3C-like proteinase, DIMETHYL SULFOXIDE, N-[(benzyloxy)carbonyl]-L-valyl-N-{(2R)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Yang, K, Liu, W.
登録日2020-08-07
公開日2021-10-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of Mpro with inhibitor r1
To Be Published
7Y9H
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BU of 7y9h by Molmil
Crystal structure of diterpene synthase VenA from Streptomyces venezuelae ATCC 15439
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Diterpene synthase VenA, ...
著者Zhang, L.L, Xie, Z.Z, Huang, J.-W, Hu, Y.C, Liu, W.D, Yang, Y, Chen, C.-C, Guo, R.-T.
登録日2022-06-24
公開日2023-06-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Molecular insights into the catalytic promiscuity of a bacterial diterpene synthase.
Nat Commun, 14, 2023
7YDS
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The structure of the bispecific antibody targeted PD-L1 and 4-1BB
分子名称: Anti-PDL1-VH-CH1, Anti-PDL1-VL-CL, Programmed cell death 1 ligand 1
著者Gao, Y, Zhu, M, Liu, W.T, Cheng, L.S, Zhu, Z.L, Niu, L.W.
登録日2022-07-04
公開日2023-07-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A bispecific antibody targeted PD-L1 and 4-1BB induces a potent antitumor immune activity in colorectal cancer without systemic toxicity
To Be Published
6KQX
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Crystal structure of Yijc from B. subtilis in complex with UDP
分子名称: URIDINE-5'-DIPHOSPHATE, Uncharacterized UDP-glucosyltransferase YjiC
著者Hu, Y.M, Dai, L.H, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T.
登録日2019-08-20
公開日2020-09-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structural dissection of unnatural ginsenoside-biosynthetic UDP-glycosyltransferase Bs-YjiC from Bacillus subtilis for substrate promiscuity.
Biochem.Biophys.Res.Commun., 534, 2021
6KQW
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Crystal structure of Yijc from B. subtilis
分子名称: CITRIC ACID, Uncharacterized UDP-glucosyltransferase YjiC
著者Hu, Y.M, Dai, L.H, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T.
登録日2019-08-20
公開日2020-09-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Structural dissection of unnatural ginsenoside-biosynthetic UDP-glycosyltransferase Bs-YjiC from Bacillus subtilis for substrate promiscuity.
Biochem.Biophys.Res.Commun., 534, 2021
6KUA
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BU of 6kua by Molmil
Crystal structure of the nicotinamidase SaPncA from Staphylococcus aureus
分子名称: Cysteine hydrolase, ZINC ION
著者Shang, F, Lan, J, Liu, W, Xu, Y, Chen, Y.
登録日2019-08-31
公開日2019-10-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.104 Å)
主引用文献Crystal structure of the nicotinamidase SaPncA from Staphylococcus aureus
To Be Published
7VX2
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BU of 7vx2 by Molmil
Crystal Structure of the Y53F/N55A/I80F/L114V/I116V mutant of LEH
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Qu, G, Li, X, Sun, Z.T, Han, X, Liu, W.D.
登録日2021-11-12
公開日2023-01-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.485 Å)
主引用文献Rational enzyme design for enabling biocatalytic Baldwin cyclization and asymmetric synthesis of chiral heterocycles.
Nat Commun, 13, 2022
7VWD
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Crystal Structure of the Y53F/N55A mutant of LEH
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Qu, G, Li, X, Sun, Z.T, Han, X, Liu, W.D.
登録日2021-11-10
公開日2023-01-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.153 Å)
主引用文献Rational enzyme design for enabling biocatalytic Baldwin cyclization and asymmetric synthesis of chiral heterocycles.
Nat Commun, 13, 2022
7VWM
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Crystal Structure of the Y53F/N55A/I116V mutant of LEH
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Qu, G, Li, X, Sun, Z.T, Han, X, Liu, W.D.
登録日2021-11-11
公開日2023-01-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Rational enzyme design for enabling biocatalytic Baldwin cyclization and asymmetric synthesis of chiral heterocycles.
Nat Commun, 13, 2022
6J03
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Crystal structure of a cyclase mutant in apo form
分子名称: 12-epi-hapalindole U synthase, CALCIUM ION, amino({3-[(3S,8aS)-1,4-dioxooctahydropyrrolo[1,2-a]pyrazin-3-yl]propyl}amino)methaniminium
著者Tang, X.K, Liu, W.D, Chen, C.C, Guo, R.T.
登録日2018-12-20
公開日2019-12-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Structural insights into the calcium dependence of Stig cyclases.
Rsc Adv, 9, 2019

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件を2024-07-03に公開中

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