6V9C
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![BU of 6v9c by Molmil](/molmil-images/mine/6v9c) | Crystal structure of FGFR4 kinase domain in complex with covalent inhibitor | Descriptor: | Fibroblast growth factor receptor 4, N-[(3R,4S)-4-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino}oxolan-3-yl]prop-2-enamide, SULFATE ION | Authors: | Liu, J, Liu, H. | Deposit date: | 2019-12-13 | Release date: | 2020-03-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery of Selective, Covalent FGFR4 Inhibitors with Antitumor Activity in Models of Hepatocellular Carcinoma. Acs Med.Chem.Lett., 11, 2020
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7LKY
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7LYX
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![BU of 7lyx by Molmil](/molmil-images/mine/7lyx) | Crystal structure of human CYP8B1 in complex with (S)-tioconazole | Descriptor: | (S)-Tioconazole, 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase, GLYCEROL, ... | Authors: | Liu, J, Scott, E.E. | Deposit date: | 2021-03-08 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The structure and characterization of human cytochrome P450 8B1 supports future drug design for nonalcoholic fatty liver disease and diabetes. J.Biol.Chem., 298, 2022
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4ATX
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![BU of 4atx by Molmil](/molmil-images/mine/4atx) | Rigor kinesin motor domain with an ordered neck-linker, docked on tubulin dimer, modelled into the 8A cryo-EM map of doublecortin- microtubules decorated with kinesin | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-1 HEAVY CHAIN, ... | Authors: | Liu, J.S, Schubert, C.R, Fu, X, Fourniol, F.J, Jaiswal, J.K, Houdusse, A, Stultz, C.M, Moores, C.A, Walsh, C.A. | Deposit date: | 2012-05-10 | Release date: | 2012-09-26 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.2 Å) | Cite: | Molecular Basis for Specific Regulation of Neuronal Kinesin- 3 Motors by Doublecortin Family Proteins. Mol.Cell, 47, 2012
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4ATU
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![BU of 4atu by Molmil](/molmil-images/mine/4atu) | Human doublecortin N-DC repeat plus linker, and tubulin (2XRP) docked into an 8A cryo-EM map of doublecortin-stabilised microtubules reconstructed in absence of kinesin | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, NEURONAL MIGRATION PROTEIN DOUBLECORTIN, ... | Authors: | Liu, J.S, Schubert, C.R, Fu, X, Fourniol, F.J, Jaiswal, J.K, Houdusse, A, Stultz, C.M, Moores, C.A, Walsh, C.A. | Deposit date: | 2012-05-09 | Release date: | 2012-09-26 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.3 Å) | Cite: | Molecular Basis for Specific Regulation of Neuronal Kinesin- 3 Motors by Doublecortin Family Proteins. Mol.Cell, 47, 2012
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426D
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![BU of 426d by Molmil](/molmil-images/mine/426d) | |
4B7Q
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![BU of 4b7q by Molmil](/molmil-images/mine/4b7q) | H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NEURAMINIDASE, ... | Authors: | Liu, J, van der Vries, E, Vachieri, S.G, Xiong, X, Collins, P.J, Walker, P.A, Haire, L.F, Hay, A.J, Schutten, M, Osterhaus, A.D.M.E, Martin, S.R, Boucher, C.A.B, Skehel, J.J, Gamblin, S.J. | Deposit date: | 2012-08-21 | Release date: | 2012-10-03 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.728 Å) | Cite: | H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis Plos Pathog., 8, 2012
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4B7R
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![BU of 4b7r by Molmil](/molmil-images/mine/4b7r) | H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis | Descriptor: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Liu, J, van der Vries, E, Vachieri, S.G, Xiong, X, Collins, P.J, Walker, P.A, Haire, L.F, Hay, A.J, Schutten, M, Osterhaus, A.D.M.E, Martin, S.R, Boucher, C.A.B, Skehel, J.J, Gamblin, S.J. | Deposit date: | 2012-08-21 | Release date: | 2012-10-03 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis Plos Pathog., 8, 2012
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463D
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![BU of 463d by Molmil](/molmil-images/mine/463d) | CALCIUM FORM OF D(CGCGAATTCGCG)2 | Descriptor: | CALCIUM ION, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3') | Authors: | Liu, J, Subirana, J.A. | Deposit date: | 1999-03-29 | Release date: | 1999-10-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of d(CGCGAATTCGCG) in the presence of Ca(2+) ions. J.Biol.Chem., 274, 1999
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4CQZ
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![BU of 4cqz by Molmil](/molmil-images/mine/4cqz) | Crystal Structure of H5 (VN1194) Gln196Arg Mutant Haemagglutinin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Liu, J, Xiong, X, Xiao, H, Martin, S.R, Coombs, P.J, Collins, P.J, Vachieri, S.G, Walker, P.A, Lin, Y.P, McCauley, J.W, Gamblin, S.J, Skehel, J.J. | Deposit date: | 2014-02-21 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Enhanced Human Receptor Binding by H5 Haemagglutinins. Virology, 456, 2014
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5WWD
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![BU of 5wwd by Molmil](/molmil-images/mine/5wwd) | Crystal structure of AtNUDX1 | Descriptor: | AMMONIUM ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Liu, J, Guan, Z, Yan, L, Zou, T, Yin, P. | Deposit date: | 2016-12-31 | Release date: | 2017-11-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.386 Å) | Cite: | Structural Insights into the Substrate Recognition Mechanism of Arabidopsis GPP-Bound NUDX1 for Noncanonical Monoterpene Biosynthesis. Mol Plant, 11, 2018
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5WY6
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![BU of 5wy6 by Molmil](/molmil-images/mine/5wy6) | Crystal structure of AtNUDX1 (E56A) | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Nudix hydrolase 1, ... | Authors: | Liu, J, Guan, Z, Yan, L, Zou, T, Yin, P. | Deposit date: | 2017-01-11 | Release date: | 2017-11-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.779 Å) | Cite: | Structural Insights into the Substrate Recognition Mechanism of Arabidopsis GPP-Bound NUDX1 for Noncanonical Monoterpene Biosynthesis. Mol Plant, 11, 2018
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4QVG
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![BU of 4qvg by Molmil](/molmil-images/mine/4qvg) | Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in its apo form | Descriptor: | SibL | Authors: | Liu, J.S, Chen, S.C, Huang, C.H, Yang, C.S, Chen, Y. | Deposit date: | 2014-07-15 | Release date: | 2015-05-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure and mechanism of an antibiotics-synthesizing 3-hydroxykynurenine C-methyltransferase Sci Rep, 5, 2015
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4U88
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4U1Q
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![BU of 4u1q by Molmil](/molmil-images/mine/4u1q) | Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in complex with 3HK and SAH | Descriptor: | (2S)-2-amino-4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid, S-ADENOSYL-L-HOMOCYSTEINE, SibL | Authors: | liu, J.S, Chen, S.C, Yang, C.S, Huang, C.H, Chen, Y. | Deposit date: | 2014-07-16 | Release date: | 2015-08-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.085 Å) | Cite: | Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in complex with 3HK and SAH To Be Published
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8GW3
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![BU of 8gw3 by Molmil](/molmil-images/mine/8gw3) | |
6IR8
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![BU of 6ir8 by Molmil](/molmil-images/mine/6ir8) | Rice WRKY/DNA complex | Descriptor: | DNA (5'-D(P*GP*AP*TP*AP*TP*TP*TP*GP*AP*CP*CP*GP*GP*A)-3'), DNA (5'-D(P*TP*CP*CP*GP*GP*TP*CP*AP*AP*AP*TP*AP*TP*C)-3'), OsWRKY45, ... | Authors: | Liu, J, Cheng, X, Wang, D. | Deposit date: | 2018-11-12 | Release date: | 2019-02-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis of dimerization and dual W-box DNA recognition by rice WRKY domain. Nucleic Acids Res., 47, 2019
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6NE8
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![BU of 6ne8 by Molmil](/molmil-images/mine/6ne8) | |
6PW1
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![BU of 6pw1 by Molmil](/molmil-images/mine/6pw1) | Cytochrome c Oxidase delta 16 | Descriptor: | (2S,3R)-heptane-1,2,3-triol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, ... | Authors: | Liu, J, Ferguson-Miller, S. | Deposit date: | 2019-07-21 | Release date: | 2019-11-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural changes at the surface of cytochrome c oxidase alter the proton-pumping stoichiometry. Biochim Biophys Acta Bioenerg, 1861, 2019
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6PW0
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![BU of 6pw0 by Molmil](/molmil-images/mine/6pw0) | Cytochrome C oxidase delta 6 mutant | Descriptor: | (2S,3R)-heptane-1,2,3-triol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, ... | Authors: | Liu, J, Ferguson-Miller, S. | Deposit date: | 2019-07-21 | Release date: | 2019-11-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural changes at the surface of cytochrome c oxidase alter the proton-pumping stoichiometry. Biochim Biophys Acta Bioenerg, 1861, 2019
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1JCC
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![BU of 1jcc by Molmil](/molmil-images/mine/1jcc) | Crystal Structure of a Novel Alanine-Zipper Trimer at 1.7 A Resolution, V13A,L16A,V20A,L23A,V27A,M30A,V34A mutations | Descriptor: | MAJOR OUTER MEMBRANE LIPOPROTEIN, ZINC ION | Authors: | Liu, J, Dai, J, Lu, M. | Deposit date: | 2001-06-08 | Release date: | 2003-06-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Zinc-Mediated Helix Capping in A Triple-Helical Protein Biochemistry, 42, 2003
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5WVA
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1I5Y
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![BU of 1i5y by Molmil](/molmil-images/mine/1i5y) | HIV-1 GP41 CORE | Descriptor: | SULFATE ION, TRANSMEMBRANE GLYCOPROTEIN (GP41) | Authors: | Liu, J, Lu, M. | Deposit date: | 2001-03-01 | Release date: | 2002-09-10 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and functional analysis of interhelical interactions in the human
immunodeficiency virus type 1 gp41 envelope glycoprotein by alanine-scanning
mutagenesis. J.Virol., 75, 2001
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1I5X
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![BU of 1i5x by Molmil](/molmil-images/mine/1i5x) | HIV-1 GP41 CORE | Descriptor: | SULFATE ION, TRANSMEMBRANE GLYCOPROTEIN (GP41) | Authors: | Liu, J, Lu, M. | Deposit date: | 2001-03-01 | Release date: | 2002-09-10 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and functional analysis of interhelical interactions in the human
immunodeficiency virus type 1 gp41 envelope glycoprotein by alanine-scanning
mutagenesis. J.Virol., 75, 2001
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1JCD
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![BU of 1jcd by Molmil](/molmil-images/mine/1jcd) | Crystal Structure of a Novel Alanine-Zipper Trimer at 1.3 A Resolution, I6A,L9A,V13A,L16A,V20A,L23A,V27A,M30A,V34A,L48A,M51A mutations | Descriptor: | MAJOR OUTER MEMBRANE LIPOPROTEIN | Authors: | Liu, J, Lu, M. | Deposit date: | 2001-06-08 | Release date: | 2003-06-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | An Alanine-Zipper Structure
Determined by Long Range
Intermolecular Interactions J.Biol.Chem., 277, 2002
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