6U7V
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![BU of 6u7v by Molmil](/molmil-images/mine/6u7v) | xRRM structure of spPof8 | 分子名称: | NITRATE ION, Protein pof8 | 著者 | Kim, J.-K, Hu, X, Yu, C, Jun, H.-I, Liu, J, Sankaran, B, Huang, L, Qiao, F. | 登録日 | 2019-09-03 | 公開日 | 2020-09-09 | 最終更新日 | 2021-03-24 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Quality-Control Mechanism for Telomerase RNA Folding in the Cell. Cell Rep, 33, 2020
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7SCD
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![BU of 7scd by Molmil](/molmil-images/mine/7scd) | Ternary complex of fixed-arm Trx-3ost5 (I299E) with 8mer-1 octasaccharide substrate and co-factor product PAP | 分子名称: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, ADENOSINE-3'-5'-DIPHOSPHATE, Thioredoxin 1,Heparan sulfate glucosamine 3-O-sulfotransferase 5 | 著者 | Wander, R, Kaminski, A.M, Krahn, J.M, Liu, J, Pedersen, L.C. | 登録日 | 2021-09-27 | 公開日 | 2022-01-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural and Substrate Specificity Analysis of 3-O-Sulfotransferase Isoform 5 to Synthesize Heparan Sulfate Acs Catalysis, 11, 2021
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7SCE
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![BU of 7sce by Molmil](/molmil-images/mine/7sce) | Ternary complex of fixed-arm Trx-3ost5 (I299E) with 8mer-2 octasaccharide substrate and co-factor product PAP | 分子名称: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, ADENOSINE-3'-5'-DIPHOSPHATE, Thioredoxin 1,Heparan sulfate glucosamine 3-O-sulfotransferase 5 | 著者 | Wander, R, Kaminski, A.M, Krahn, J.M, Liu, J, Pedersen, L.C. | 登録日 | 2021-09-27 | 公開日 | 2022-01-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural and Substrate Specificity Analysis of 3-O-Sulfotransferase Isoform 5 to Synthesize Heparan Sulfate Acs Catalysis, 11, 2021
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4G42
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![BU of 4g42 by Molmil](/molmil-images/mine/4g42) | Structure of the Chicken MHC Class I Molecule BF2*0401 complexed to pepitde P8D | 分子名称: | 8-MERIC PEPTIDE P8D, Beta-2 microglobulin, MHC class I alpha chain 2 | 著者 | Zhang, J, Chen, Y, Qi, J, Gao, F, Liu, J, Kaufman, J, Xia, C, Gao, G.F. | 登録日 | 2012-07-16 | 公開日 | 2012-11-21 | 実験手法 | X-RAY DIFFRACTION (2.294 Å) | 主引用文献 | Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens. J.Immunol., 189, 2012
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7NTH
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![BU of 7nth by Molmil](/molmil-images/mine/7nth) | Structure of TAK1 in complex with compound 54 | 分子名称: | 2-[[5-[[2-[bis(fluoranyl)methoxy]phenyl]methyl-[(2~{R})-1-(methylamino)-1-oxidanylidene-propan-2-yl]carbamoyl]-1~{H}-imidazol-2-yl]carbonyl]isoindole-5-carboxamide, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Veerman, J.J.N, Bruseker, Y.B, Damen, E, Heijne, E.H, van Bruggen, W, Hekking, K.F.W, Winkel, R, Hupp, C.D, Keefe, A.D, Liu, J, Thomson, H.A, Zhang, Y, Cuozzo, J.W, McRiner, A.J, Mulvihill, M.J, van Rijnsbergen, P, Zech, B, Renzetti, L.M, Babiss, L, Mueller, G. | 登録日 | 2021-03-09 | 公開日 | 2021-04-07 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Discovery of 2,4-1 H -Imidazole Carboxamides as Potent and Selective TAK1 Inhibitors. Acs Med.Chem.Lett., 12, 2021
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7NTI
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![BU of 7nti by Molmil](/molmil-images/mine/7nti) | Structure of TAK1 in complex with compound 22 | 分子名称: | DIMETHYL SULFOXIDE, GLYCEROL, Mitogen-activated protein kinase 7,TGF-beta-activated kinase 1 and MAP3K7-binding protein 1, ... | 著者 | Veerman, J.J.N, Bruseker, Y.B, Damen, E, Heijne, E.H, van Bruggen, W, Hekking, K.F.W, Winkel, R, Hupp, C.D, Keefe, A.D, Liu, J, Thomson, H.A, Zhang, Y, Cuozzo, J.W, McRiner, A.J, Mulvihill, M.J, van Rijnsbergen, P, Zech, B, Renzetti, L.M, Babiss, L, Mueller, G. | 登録日 | 2021-03-09 | 公開日 | 2021-04-07 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Discovery of 2,4-1 H -Imidazole Carboxamides as Potent and Selective TAK1 Inhibitors. Acs Med.Chem.Lett., 12, 2021
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5TTF
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![BU of 5ttf by Molmil](/molmil-images/mine/5ttf) | Crystal structure of catalytic domain of G9a with MS012 | 分子名称: | CHLORIDE ION, Histone-lysine N-methyltransferase EHMT2, N4-(1-methylpiperidin-4-yl)-N2-hexyl-6,7-dimethoxyquinazoline-2,4-diamine, ... | 著者 | DONG, A, ZENG, H, LIU, J, XIONG, Y, BABAULT, N, JIN, J, TEMPEL, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, WU, H, BROWN, P.J, Structural Genomics Consortium (SGC) | 登録日 | 2016-11-03 | 公開日 | 2016-12-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Discovery of Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase. J. Med. Chem., 60, 2017
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5TUY
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![BU of 5tuy by Molmil](/molmil-images/mine/5tuy) | Structure of human G9a SET-domain (EHMT2) in complex with inhibitor MS0124 | 分子名称: | 6,7-dimethoxy-N-(1-methylpiperidin-4-yl)-2-(morpholin-4-yl)quinazolin-4-amine, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYLMETHIONINE, ... | 著者 | Babault, N, Xiong, Y, Liu, J, Jin, J. | 登録日 | 2016-11-07 | 公開日 | 2017-02-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Discovery of Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase. J. Med. Chem., 60, 2017
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5TUZ
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![BU of 5tuz by Molmil](/molmil-images/mine/5tuz) | Structure of human GLP SET-domain (EHMT1) in complex with inhibitor MS0124 | 分子名称: | 1,2-ETHANEDIOL, 6,7-dimethoxy-N-(1-methylpiperidin-4-yl)-2-(morpholin-4-yl)quinazolin-4-amine, Histone-lysine N-methyltransferase EHMT1, ... | 著者 | Babault, N, Xiong, Y, Liu, J, Jin, J. | 登録日 | 2016-11-07 | 公開日 | 2017-02-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Discovery of Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase. J. Med. Chem., 60, 2017
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5TTG
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![BU of 5ttg by Molmil](/molmil-images/mine/5ttg) | Crystal structure of catalytic domain of GLP with MS012 | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | DONG, A, ZENG, H, LIU, J, XIONG, Y, BABAULT, N, JIN, J, TEMPEL, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, WU, H, BROWN, P.J, Structural Genomics Consortium (SGC) | 登録日 | 2016-11-03 | 公開日 | 2017-02-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Discovery of Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase. J. Med. Chem., 60, 2017
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1N6H
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![BU of 1n6h by Molmil](/molmil-images/mine/1n6h) | Crystal Structure of Human Rab5a | 分子名称: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C. | 登録日 | 2002-11-11 | 公開日 | 2002-11-27 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop J.Biol.Chem., 278, 2003
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1N6I
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![BU of 1n6i by Molmil](/molmil-images/mine/1n6i) | Crystal Structure of Human Rab5a A30P mutant Complex with GDP | 分子名称: | BETA-MERCAPTOETHANOL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C. | 登録日 | 2002-11-11 | 公開日 | 2002-11-27 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop J.Biol.Chem., 278, 2003
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1N6K
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![BU of 1n6k by Molmil](/molmil-images/mine/1n6k) | Crystal Structure of Human Rab5a A30P mutant complex with GDP and aluminum fluoride | 分子名称: | ALUMINUM FLUORIDE, BETA-MERCAPTOETHANOL, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C. | 登録日 | 2002-11-11 | 公開日 | 2002-11-27 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop J.Biol.Chem., 278, 2003
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1N6L
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![BU of 1n6l by Molmil](/molmil-images/mine/1n6l) | Crystal Structure of Human Rab5a A30P mutant complex with GTP | 分子名称: | BETA-MERCAPTOETHANOL, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C. | 登録日 | 2002-11-11 | 公開日 | 2002-11-27 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop J.Biol.Chem., 278, 2003
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1N6O
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![BU of 1n6o by Molmil](/molmil-images/mine/1n6o) | Crystal Structure of Human Rab5a A30K mutant complex with GppNHp | 分子名称: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C. | 登録日 | 2002-11-11 | 公開日 | 2002-11-27 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop J.Biol.Chem., 278, 2003
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1N6N
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![BU of 1n6n by Molmil](/molmil-images/mine/1n6n) | Crystal Structure of Human Rab5a A30R mutant complex with GppNHp | 分子名称: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C. | 登録日 | 2002-11-11 | 公開日 | 2002-11-27 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop J.Biol.Chem., 278, 2003
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1N6P
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![BU of 1n6p by Molmil](/molmil-images/mine/1n6p) | Crystal Structure of Human Rab5a A30E mutant complex with GppNHp | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-5A | 著者 | Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C. | 登録日 | 2002-11-11 | 公開日 | 2002-11-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop J.Biol.Chem., 278, 2003
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1N6R
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![BU of 1n6r by Molmil](/molmil-images/mine/1n6r) | Crystal Structure of Human Rab5a A30L mutant complex with GppNHp | 分子名称: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C. | 登録日 | 2002-11-11 | 公開日 | 2002-11-27 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop J.Biol.Chem., 278, 2003
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4G43
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![BU of 4g43 by Molmil](/molmil-images/mine/4g43) | Structure of the chicken MHC class I molecule BF2*0401 complexed to P5E | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 8-MERIC PEPTIDE P5E, Beta-2 microglobulin, ... | 著者 | Zhang, J, Chen, Y, Qi, J, Gao, F, Liu, J, Kaufman, J, Xia, C, Gao, G.F. | 登録日 | 2012-07-16 | 公開日 | 2012-11-21 | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | 主引用文献 | Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens. J.Immunol., 189, 2012
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3ISW
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![BU of 3isw by Molmil](/molmil-images/mine/3isw) | Crystal structure of filamin-A immunoglobulin-like repeat 21 bound to an N-terminal peptide of CFTR | 分子名称: | Cystic fibrosis transmembrane conductance regulator, Filamin-A | 著者 | Xu, Z, Page, R, Qin, J, Ithychanda, S.S, Liu, J.M, Misra, S. | 登録日 | 2009-08-27 | 公開日 | 2010-04-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Biochemical basis of the interaction between cystic fibrosis transmembrane conductance regulator and immunoglobulin-like repeats of filamin. J.Biol.Chem., 285, 2010
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2NOC
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![BU of 2noc by Molmil](/molmil-images/mine/2noc) | Solution Structure of Putative periplasmic protein: Northest Structural Genomics Target StR106 | 分子名称: | Putative periplasmic protein | 著者 | Zhang, Q, Liu, G, Wang, H, Nwosu, C, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-10-25 | 公開日 | 2006-11-28 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of Putative periplasmic protein: Northest Structural Genomics Target StR106 To be Published
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5H4D
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![BU of 5h4d by Molmil](/molmil-images/mine/5h4d) | Crystal structure of hSIRT3 in complex with a specific agonist Amiodarone hydrochloride | 分子名称: | (2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone, 7-AMINO-4-METHYL-CHROMEN-2-ONE, ARG-HIS-LYS, ... | 著者 | Zhang, S, Fu, L, Liu, J, Liu, B. | 登録日 | 2016-10-31 | 公開日 | 2017-11-08 | 最終更新日 | 2023-04-05 | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | 主引用文献 | Crystal structure of hSIRT3 in complex with a specific agonist Amiodarone hydrochloride To Be Published
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5WWI
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![BU of 5wwi by Molmil](/molmil-images/mine/5wwi) | Crystal Structure of HLA-A*2402 in complex with avian influenza A(H7N9) virus-derived peptide H7-25 (data set 1) | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ... | 著者 | Zhao, M, Liu, K, Chai, Y, Qi, J, Liu, J, Gao, G.F. | 登録日 | 2017-01-01 | 公開日 | 2018-01-17 | 最終更新日 | 2019-07-31 | 実験手法 | X-RAY DIFFRACTION (3.194 Å) | 主引用文献 | Crystal Structure of HLA-A*2402 in complex with avian influenza A(H7N9) virus-derived peptide H7-25 (data set 1). To Be Published
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8EB7
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![BU of 8eb7 by Molmil](/molmil-images/mine/8eb7) | |
8EAO
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![BU of 8eao by Molmil](/molmil-images/mine/8eao) | |