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PDB: 53 件

2IBG
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Crystal Structure of Hedgehog Bound to the FNIII Domains of Ihog
分子名称: CG9211-PA, PHOSPHATE ION, Protein hedgehog
著者McLellan, J.S, Leahy, D.J.
登録日2006-09-11
公開日2006-10-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of a heparin-dependent complex of Hedgehog and Ihog.
Proc.Natl.Acad.Sci.Usa, 103, 2006
3TNU
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Heterocomplex of coil 2B domains of human intermediate filament proteins, keratin 5 (KRT5) and keratin 14 (KRT14)
分子名称: Keratin, type I cytoskeletal 14, type II cytoskeletal 5
著者Lee, C.H, Kim, M.S, Leahy, D.J, Coulombe, P.A.
登録日2011-09-02
公開日2012-06-20
最終更新日2012-08-01
実験手法X-RAY DIFFRACTION (3.005 Å)
主引用文献Structural basis for heteromeric assembly and perinuclear organization of keratin filaments.
Nat.Struct.Mol.Biol., 19, 2012
1DDW
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HOMER EVH1 DOMAIN UNLIGANDED
分子名称: GLGF-DOMAIN PROTEIN HOMER
著者Beneken, J, Tu, J.C, Xiao, B, Worley, P.F, Leahy, D.J.
登録日1999-11-11
公開日2000-05-10
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the Homer EVH1 domain-peptide complex reveals a new twist in polyproline recognition.
Neuron, 26, 2000
2IC2
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Crystal Structure of the First FNIII Domain of Ihog
分子名称: CG9211-PA, SULFATE ION
著者McLellan, J.S, Leahy, D.J.
登録日2006-09-12
公開日2006-10-24
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure of a heparin-dependent complex of Hedgehog and Ihog.
Proc.Natl.Acad.Sci.Usa, 103, 2006
1S78
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Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Pertuzumab Fab heavy chain, ...
著者Franklin, M.C, Carey, K.D, Vajdos, F.F, Leahy, D.J, de Vos, A.M, Sliwkowski, M.X.
登録日2004-01-29
公開日2004-04-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex.
Cancer Cell, 5, 2004
2IBB
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Crystal Structure of the First and Second FNIII Domains of Ihog
分子名称: CG9211-PA, SULFATE ION
著者McLellan, J.S, Leahy, D.J.
登録日2006-09-11
公開日2006-10-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of a heparin-dependent complex of Hedgehog and Ihog.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2ORZ
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Structural Basis for Ligand Binding and Heparin Mediated Activation of Neuropilin
分子名称: Neuropilin-1, Tuftsin
著者Vander Kooi, C.W, Jusino, M.A, Perman, B, Neau, D.B, Bellamy, H.D, Leahy, D.J.
登録日2007-02-05
公開日2007-04-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis for ligand and heparin binding to neuropilin B domains.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2ORX
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Structural Basis for Ligand Binding and Heparin Mediated Activation of Neuropilin
分子名称: Neuropilin-1
著者Vander Kooi, C.W, Jusino, M.A, Perman, B, Neau, D.B, Bellamy, H.D, Leahy, D.J.
登録日2007-02-05
公開日2007-04-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for ligand and heparin binding to neuropilin B domains
Proc.Natl.Acad.Sci.Usa, 104, 2007
2P8V
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Crystal structure of human Homer3 EVH1 domain
分子名称: Homer protein homolog 3, SULFATE ION
著者Bouyain, S, Tu, J, Huang, G.N, Worley, P.F, Leahy, D.
登録日2007-03-23
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins.
Science, 319, 2008
1IJX
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CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF SECRETED FRIZZLED-RELATED PROTEIN 3 (SFRP-3;FZB)
分子名称: SECRETED FRIZZLED-RELATED SEQUENCE PROTEIN 3, SULFATE ION
著者Dann III, C.E, Hsieh, J.C, Rattner, A, Sharma, D, Nathans, J, Leahy, D.J.
登録日2001-04-30
公開日2001-07-11
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains.
Nature, 412, 2001
1IJY
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CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF MOUSE FRIZZLED 8 (MFZ8)
分子名称: FRIZZLED HOMOLOG 8
著者Dann III, C.E, Hsieh, J.C, Rattner, A, Sharma, D, Nathans, J, Leahy, D.J.
登録日2001-05-01
公開日2001-07-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains.
Nature, 412, 2001
3BXL
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Crystal structure of the R-type calcium channeL (CaV2.3) IQ domain and CA2+calmodulin complex
分子名称: CALCIUM ION, Calmodulin, SULFATE ION, ...
著者Mori, M.X, Vander Kooi, C.W, Leahy, D.J, Yue, D.T.
登録日2008-01-14
公開日2008-03-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the CaV2 IQ domain in complex with Ca2+/calmodulin
To be Published
3BXK
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Crystal structure of the P/Q-type calcium channel (CaV2.1) IQ domain and CA2+calmodulin complex
分子名称: CALCIUM ION, Calmodulin, SULFATE ION, ...
著者Mori, M.X, Vander Kooi, C.W, Leahy, D.J, Yue, D.T.
登録日2008-01-14
公開日2008-03-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of the P/Q-type calcium channel (CaV2.1) IQ domain and CA2+calmodulin complex
To be Published
2OGB
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BU of 2ogb by Molmil
Crystal structure of the C-terminal domain of mouse Nrdp1
分子名称: GLYCEROL, RING finger protein 41, THIOCYANATE ION
著者Bouyain, S, Leahy, D.J.
登録日2007-01-05
公開日2007-01-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure-based mutagenesis of the substrate-recognition domain of Nrdp1/FLRF identifies the binding site for the receptor tyrosine kinase ErbB3.
Protein Sci., 16, 2007
1YN5
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Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens
分子名称: EapH2
著者Geisbrecht, B.V, Hamaoka, B.Y, Perman, B, Zemla, A, Leahy, D.J.
登録日2005-01-23
公開日2005-03-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens.
J.Biol.Chem., 280, 2005
1YN3
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Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens
分子名称: truncated cell surface protein map-w
著者Geisbrecht, B.V, Hamaoka, B.Y, Perman, B, Zemla, A, Leahy, D.J.
登録日2005-01-23
公開日2005-03-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens.
J.Biol.Chem., 280, 2005
1YN4
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Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens
分子名称: EapH1, ZINC ION
著者Geisbrecht, B.V, Hamaoka, B.Y, Perman, B, Zemla, A, Leahy, D.J.
登録日2005-01-23
公開日2005-03-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens.
J.Biol.Chem., 280, 2005
3N1F
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BU of 3n1f by Molmil
Crystal Structure of IhhN bound to CDOFn3
分子名称: CALCIUM ION, Cell adhesion molecule-related/down-regulated by oncogenes, Indian hedgehog protein, ...
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-15
公開日2010-06-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1M
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BU of 3n1m by Molmil
Crystal Structure of IhhN bound to BOCFn3
分子名称: Brother of CDO, CALCIUM ION, Indian hedgehog protein, ...
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-15
公開日2010-06-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1Q
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Crystal Structure of DhhN bound to CDOFn3
分子名称: CALCIUM ION, Cell adhesion molecule-related/down-regulated by oncogenes, Desert hedgehog protein, ...
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-16
公開日2010-06-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1G
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Crystal structure of DhhN bound to BOCFn3
分子名称: Brother of CDO, CALCIUM ION, Desert hedgehog protein, ...
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-15
公開日2010-06-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
1SZH
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Crystal Structure of C. elegans HER-1
分子名称: ACETATE ION, Her-1 protein
著者Hamaoka, B.Y, Dann III, C.E, Geisbrecht, B.V, Leahy, D.J.
登録日2004-04-05
公開日2004-08-10
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of Caenorhabditis elegans HER-1 and characterization of the interaction between HER-1 and TRA-2A.
Proc.Natl.Acad.Sci.USA, 101, 2004
3N1R
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Crystal Structure of ShhN
分子名称: CALCIUM ION, Sonic hedgehog protein, ZINC ION
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-16
公開日2010-06-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Crystal Structure of ShhN
TO BE PUBLISHED
3N1P
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Crystal Structure of IhhN bound to BOCFn3
分子名称: Brother of CDO, CALCIUM ION, Indian hedgehog protein, ...
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-16
公開日2010-06-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1O
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Crystal structure of IhhN
分子名称: CALCIUM ION, Indian hedgehog protein, ZINC ION
著者Kavran, J.M, Leahy, D.J.
登録日2010-05-16
公開日2010-06-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010

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