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PDB: 435 件

3PIQ
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Crystal structure of human 2909 Fab, a quaternary structure-specific antibody against HIV-1
分子名称: Human monoclonal antibody 2909 Fab heavy chain, Human monoclonal antibody 2909 Fab light chain
著者Changela, A, Gorny, M.K, Zolla-Pazner, S, Kwong, P.D.
登録日2010-11-07
公開日2011-01-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.325 Å)
主引用文献Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1.
J.Virol., 85, 2011
3QWO
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Crystal structure of a motavizumab epitope-scaffold bound to motavizumab Fab
分子名称: 1,2-ETHANEDIOL, SULFATE ION, motavizumab epitope scaffold, ...
著者McLellan, J.S, Kwong, P.D.
登録日2011-02-28
公開日2011-05-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Design and characterization of epitope-scaffold immunogens that present the motavizumab epitope from respiratory syncytial virus.
J.Mol.Biol., 409, 2011
3R6J
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BU of 3r6j by Molmil
Crystal Structure of the Capsid P Domain from Norwalk Virus Strain Hiroshima/1999
分子名称: 1,2-ETHANEDIOL, VP1 protein
著者Hansman, G.S, Biertumpfel, C, McLellan, J.S, Georgiev, I, Chen, L, Zhou, T, Katayama, K, Kwong, P.D.
登録日2011-03-21
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3RPT
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BU of 3rpt by Molmil
Crystal structure of the anti-HIV b12 scaffold protein
分子名称: Endoglucanase E-2, SULFATE ION
著者Chen, L, Kwong, P.D.
登録日2011-04-27
公開日2011-12-21
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.303 Å)
主引用文献Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold.
Science, 334, 2011
3RJQ
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Crystal structure of anti-HIV llama VHH antibody A12 in complex with C186 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C186 gp120, Llama VHH A12
著者Chen, L, McLellan, J.S, Kwon, Y.D, Schmidt, S, Wu, X, Zhou, T, Yang, Y, Zhang, B, Forsman, A, Weiss, R.A, Verrips, T, Mascola, J, Kwong, P.D.
登録日2011-04-15
公開日2012-05-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Crystal structure of anti-HIV A12 VHH of llama antibody in complex with C1086 gp120
To be Published
3RY8
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Structural basis for norovirus inhibition and fucose mimicry by citrate
分子名称: 1,2-ETHANEDIOL, CITRATE ANION, Capsid protein
著者Hansman, G.S, McLellan, J.S, Kwong, P.D.
登録日2011-05-11
公開日2011-11-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural basis for norovirus inhibition and fucose mimicry by citrate.
J.Virol., 86, 2012
3Q38
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Crystal structure of P domain from norwalk virus strain vietnam 026 in complex with HBGA type B (triglycan)
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2010-12-21
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3Q3A
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BU of 3q3a by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with HBGA type H2 (triglycan)
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2010-12-21
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3R0M
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Crystal structure of anti-HIV llama VHH antibody A12
分子名称: Llama VHH A12, SULFATE ION
著者Chen, L, McLellan, J.S, Kwon, Y.D, Schmidt, S, Wu, X, Zhou, T, Yang, Y, Zhang, B, Forsman, A, Weiss, R.A, Verrips, T, Mascola, J, Kwong, P.D.
登録日2011-03-08
公開日2012-03-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Single-Headed Immunoglobulins Efficiently Penetrate CD4-Binding Site and Effectively Neutralize HIV-1
To be Published
3Q39
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Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with HBGA type H2 (diglycan)
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2010-12-21
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3RRR
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BU of 3rrr by Molmil
Structure of the RSV F protein in the post-fusion conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
著者McLellan, J.S, Yongping, Y, Graham, B.S, Kwong, P.D.
登録日2011-04-30
公開日2011-06-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.821 Å)
主引用文献Structure of respiratory syncytial virus fusion glycoprotein in the postfusion conformation reveals preservation of neutralizing epitopes.
J.Virol., 85, 2011
3TGR
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BU of 3tgr by Molmil
Crystal structure of unliganded HIV-1 clade C strain C1086 gp120 core
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 clade C1086 gp120
著者Kwon, Y.D, Kwong, P.D.
登録日2011-08-17
公開日2012-04-04
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops.
Proc.Natl.Acad.Sci.USA, 109, 2012
3TCL
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BU of 3tcl by Molmil
Crystal Structure of HIV-1 Neutralizing Antibody CH04
分子名称: CH04 Heavy Chain Fab, CH04 Light Chain Fab, IMIDAZOLE
著者Louder, R.K, McLellan, J.S, Pancera, M, Yang, Y, Zhang, B, Bonsignori, M, Kwong, P.D.
登録日2011-08-09
公開日2011-11-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.906 Å)
主引用文献Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3TGT
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Crystal structure of unliganded HIV-1 clade A/E strain 93TH057 gp120 core
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 clade A/E 93TH057 gp120
著者Kwon, Y.D, Kwong, P.D.
登録日2011-08-17
公開日2012-04-04
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops.
Proc.Natl.Acad.Sci.USA, 109, 2012
3TGQ
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BU of 3tgq by Molmil
Crystal structure of unliganded HIV-1 clade B strain YU2 gp120 core
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 YU2 gp120
著者Kwon, Y.D, Kwong, P.D.
登録日2011-08-17
公開日2012-04-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops.
Proc.Natl.Acad.Sci.USA, 109, 2012
3Q6Q
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BU of 3q6q by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with disordered HBGA type Lea
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2011-01-03
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3Q6R
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BU of 3q6r by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with disordered HBGA type Lex
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE
著者Hansman, G.S, Biertumpfel, C, McLellan, J.S, Chen, L, Georgiev, I, Katayama, K, Kwong, P.D.
登録日2011-01-03
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3TGS
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BU of 3tgs by Molmil
Crystal structure of HIV-1 clade C strain C1086 gp120 core in complex with NBD-556
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 clade C1086 gp120 core, N-(4-chlorophenyl)-N'-(2,2,6,6-tetramethylpiperidin-4-yl)ethanediamide
著者Kwon, Y.D, Kwong, P.D.
登録日2011-08-17
公開日2012-04-04
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops.
Proc.Natl.Acad.Sci.USA, 109, 2012
3RRT
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BU of 3rrt by Molmil
Structure of the RSV F protein in the post-fusion conformation
分子名称: Fusion glycoprotein F0
著者McLellan, J.S, Yongping, Y, Graham, B.S, Kwong, P.D.
登録日2011-04-30
公開日2011-06-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of respiratory syncytial virus fusion glycoprotein in the postfusion conformation reveals preservation of neutralizing epitopes.
J.Virol., 85, 2011
3R6K
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BU of 3r6k by Molmil
Crystal Structure of the Capsid P Domain from Norwalk Virus Strain Hiroshima/1999 in complex with HBGA type B (triglycan)
分子名称: 1,2-ETHANEDIOL, VP1 protein, alpha-L-fucopyranose-(1-2)-[alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose
著者Hansman, G.S, Biertumpfel, C, McLellan, J.S, Georgiev, I, Chen, L, Zhou, T, Katayama, K, Kwong, P.D.
登録日2011-03-21
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3TIH
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BU of 3tih by Molmil
Crystal structure of unliganded HIV-1 clade C strain ZM109F.PB4 gp120 core
分子名称: HIV-1 clade C ZM109F.PB4 gp120
著者Kwon, Y.D, Kwong, P.D.
登録日2011-08-20
公開日2012-04-04
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops.
Proc.Natl.Acad.Sci.USA, 109, 2012
3U4B
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BU of 3u4b by Molmil
CH04H/CH02L Fab P4
分子名称: CH02 Light chain, CH04 Heavy chain
著者Pancera, M, Louder, R, Mclellan, J.S, KWong, P.D.
登録日2011-10-07
公開日2011-11-30
最終更新日2011-12-21
実験手法X-RAY DIFFRACTION (2.893 Å)
主引用文献Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U36
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Crystal Structure of PG9 Fab
分子名称: PG9 Fab heavy chain, PG9 Fab light chain, SULFATE ION
著者McLellan, J.S, Kwong, P.D.
登録日2011-10-04
公開日2011-11-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.281 Å)
主引用文献Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U4E
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Crystal Structure of PG9 Fab in Complex with V1V2 Region from HIV-1 strain CAP45
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PG9 Heavy Chain, PG9 Light Chain, ...
著者Gorman, J, McLellan, J, Pancera, M, Kwong, P.D.
登録日2011-10-07
公開日2011-11-30
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.185 Å)
主引用文献Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
4JHW
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Crystal Structure of Respiratory Syncytial Virus Fusion Glycoprotein Stabilized in the Prefusion Conformation by Human Antibody D25
分子名称: D25 antigen-binding fragment heavy chain, D25 light chain, Fusion glycoprotein F0
著者Mclellan, J.S, Chen, M, Leung, S, Graepel, K.W, Du, X, Yang, Y, Zhou, T, Baxa, U, Yasuda, E, Beaumont, T, Kumar, A, Modjarrad, K, Zheng, Z, Zhao, M, Xia, N, Kwong, P.D, Graham, B.S.
登録日2013-03-05
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.
Science, 340, 2013

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