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PDB: 195 results

2WJX
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Crystal structure of the human ionotropic glutamate receptor GluR2 ATD region at 4.1 A resolution
Descriptor: GLUTAMATE RECEPTOR 2
Authors:Clayton, A, Siebold, C, Gilbert, R.J.C, Sutton, G.C, Harlos, K, McIlhinney, R.A.J, Jones, E.Y, Aricescu, A.R.
Deposit date:2009-06-01
Release date:2009-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Crystal Structure of the Glur2 Amino-Terminal Domain Provides Insights Into the Architecture and Assembly of Ionotropic Glutamate Receptors.
J.Mol.Biol., 392, 2009
2WFX
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Crystal structure of the complex between human hedgehog-interacting protein HIP and Sonic Hedgehog in the presence of calcium
Descriptor: CALCIUM ION, HEDGEHOG-INTERACTING PROTEIN, SODIUM ION, ...
Authors:Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C.
Deposit date:2009-04-15
Release date:2009-06-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
2WFT
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Crystal structure of the human HIP ectodomain
Descriptor: CHLORIDE ION, HEDGEHOG-INTERACTING PROTEIN, SODIUM ION
Authors:Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C.
Deposit date:2009-04-15
Release date:2009-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
2WFR
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Crystal structure of the N-terminal signalling domain of human Dhh with calcium
Descriptor: CALCIUM ION, DESERT HEDGEHOG PROTEIN N-PRODUCT, SULFATE ION, ...
Authors:Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C.
Deposit date:2009-04-14
Release date:2009-06-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
7WAI
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Glutamyl-tRNA synthetase from Plasmodium falciparum (PfERS)
Descriptor: CHLORIDE ION, Glutamyl-tRNA synthetase
Authors:Sharma, V, Manickam, Y, Harlos, K, Sharma, A.
Deposit date:2021-12-14
Release date:2022-12-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:Structural characterization of glutamyl-tRNA synthetase (GluRS) from Plasmodium falciparum.
Mol.Biochem.Parasitol., 253, 2022
2X10
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Crystal structure of the complete EphA2 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, EPHRIN TYPE-A RECEPTOR 2
Authors:Seiradake, E, Harlos, K, Sutton, G, Aricescu, A.R, Jones, E.Y.
Deposit date:2009-12-21
Release date:2010-03-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:An Extracellular Steric Seeding Mechanism for Eph-Ephrin Signalling Platform Assembly
Nat.Struct.Mol.Biol., 17, 2010
2WJW
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Crystal structure of the human ionotropic glutamate receptor GluR2 ATD region at 1.8 A resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CHLORIDE ION, ...
Authors:Clayton, A, Siebold, C, Gilbert, R.J.C, Sutton, G.C, Harlos, K, McIlhinney, R.A.J, Jones, E.Y, Aricescu, A.R.
Deposit date:2009-06-01
Release date:2009-08-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the Glur2 Amino-Terminal Domain Provides Insights Into the Architecture and Assembly of Ionotropic Glutamate Receptors.
J.Mol.Biol., 392, 2009
2X46
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Crystal Structure of SeMet Arg r 1
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ALLERGEN ARG R 1
Authors:Paesen, G.C, Siebold, C, Syme, N, Harlos, K, Graham, S.C, Hilger, C, Homans, S.W, Hentges, F, Stuart, D.I.
Deposit date:2010-01-28
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:Crystal Structure of the Allergen Arg R 1, a Histamine-Binding Lipocalin from a Soft Tick
To be Published
2WNG
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complete extracellular structure of human signal regulatory protein (SIRP) alpha
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1
Authors:Hatherley, D, Graham, S.C, Harlos, K, Stuart, D.I, Barclay, A.N.
Deposit date:2009-07-09
Release date:2009-07-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structure of Signal-Regulatory Protein Alpha: A Link to Antigen Receptor Evolution.
J.Biol.Chem., 284, 2009
2UUX
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Structure of the tryptase inhibitor TdPI from a tick
Descriptor: SULFATE ION, TRYPTASE INHIBITOR
Authors:Siebold, C, Paesen, G.C, Harlos, K, Peacey, M.F, Nuttall, P.A, Stuart, D.I.
Deposit date:2007-03-08
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A Tick Protein with a Modified Kunitz Fold Inhibits Human Tryptase.
J.Mol.Biol., 368, 2007
2WAH
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Crystal Structure of an IgG1 Fc Glycoform (Man9GlcNAc2)
Descriptor: IG GAMMA-1 CHAIN C REGION, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Crispin, M, Bowden, T.A, Coles, C.H, Harlos, K, Aricescu, A.R, Harvey, D.J, Stuart, D.I, Jones, E.Y.
Deposit date:2009-02-06
Release date:2009-03-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Carbohydrate and Domain Architecture of an Immature Antibody Glycoform Exhibiting Enhanced Effector Functions
J.Mol.Biol., 387, 2009
2W8X
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Structure of the tick ion-channel modulator Ra-KLP
Descriptor: ACETATE ION, GLYCEROL, IMIDAZOLE, ...
Authors:Paesen, G.C, Siebold, C, Dallas, M, Peers, C, Harlos, K, Nuttall, P.A, Nunn, M.A, Stuart, D.I, Esnouf, R.M.
Deposit date:2009-01-20
Release date:2009-05-05
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:An Ion-Channel Modulator from the Saliva of the Brown Ear Tick Has a Highly Modified Kunitz/Bpti Structure.
J.Mol.Biol., 389, 2009
2X11
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Crystal structure of the complete EphA2 ectodomain in complex with ephrin A5 receptor binding domain
Descriptor: EPHRIN TYPE-A RECEPTOR 2, EPHRIN-A5
Authors:Seiradake, E, Harlos, K, Sutton, G, Aricescu, A.R, Jones, E.Y.
Deposit date:2009-12-21
Release date:2010-03-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (4.83 Å)
Cite:An Extracellular Steric Seeding Mechanism for Eph-Ephrin Signalling Platform Assembly
Nat.Struct.Mol.Biol., 17, 2010
2WS9
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Equine Rhinitis A Virus at Low pH
Descriptor: P1
Authors:Fry, E.E, Tuthill, T.J, Harlos, K, Walter, T.S, Knowles, N.J, Gropelli, E, Rowlands, D.J, Stuart, D.I.
Deposit date:2009-09-04
Release date:2010-08-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Equine Rhinitis a Virus and its Low Ph Empty Particle: Clues Towards an Aphthovirus Entry Mechanism?
Plos Pathog., 5, 2009
1CCZ
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BU of 1ccz by Molmil
CRYSTAL STRUCTURE OF THE CD2-BINDING DOMAIN OF CD58 (LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3) AT 1.8-A RESOLUTION
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (CD58)
Authors:Ikemizu, S, Sparks, L.M, Van Der Merwe, P.A, Harlos, K, Stuart, D.I, Jones, E.Y, Davis, S.J.
Deposit date:1999-03-02
Release date:1999-04-05
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the CD2-binding domain of CD58 (lymphocyte function-associated antigen 3) at 1.8-A resolution.
Proc.Natl.Acad.Sci.USA, 96, 1999
1E5S
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BU of 1e5s by Molmil
Proline 3-hydroxylase (type II) - Iron form
Descriptor: FE (II) ION, PROLINE OXIDASE, SULFATE ION
Authors:Clifton, I.J, Hsueh, L.C, Baldwin, J.E, Schofield, C.J, Harlos, K.
Deposit date:2000-07-28
Release date:2001-07-26
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of proline 3-hydroxylase. Evolution of the family of 2-oxoglutarate dependent oxygenases.
Eur.J.Biochem., 268, 2001
1E5R
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BU of 1e5r by Molmil
Proline 3-hydroxylase (type II) -apo form
Descriptor: PROLINE OXIDASE
Authors:Clifton, I.J, Hsueh, L.C, Baldwin, J.E, Schofield, C.J, Harlos, K.
Deposit date:2000-07-28
Release date:2001-07-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of proline 3-hydroxylase. Evolution of the family of 2-oxoglutarate dependent oxygenases.
Eur.J.Biochem., 268, 2001
7DPI
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BU of 7dpi by Molmil
Plasmodium falciparum cytoplasmic Phenylalanyl-tRNA synthetase in complex with BRD7929
Descriptor: (8R,9S,10S)-10-[(dimethylamino)methyl]-N-(4-methoxyphenyl)-9-[4-(2-phenylethynyl)phenyl]-1,6-diazabicyclo[6.2.0]decane-6-carboxamide, MAGNESIUM ION, Phenylalanine--tRNA ligase, ...
Authors:Manmohan, S, Malhotra, N, Harlos, K, Manickam, Y, Sharma, A.
Deposit date:2020-12-19
Release date:2022-03-23
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.597 Å)
Cite:Inhibition of Plasmodium falciparum phenylalanine tRNA synthetase provides opportunity for antimalarial drug development.
Structure, 30, 2022
5L81
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Crystal structure of the PH domain of murine kindlin-3
Descriptor: Fermitin family homolog 3, SODIUM ION
Authors:Ni, T, Harlos, K, Gilbert, R.J.C.
Deposit date:2016-06-06
Release date:2017-01-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structure and lipid-binding properties of the kindlin-3 pleckstrin homology domain.
Biochem. J., 474, 2017
7EL5
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BU of 7el5 by Molmil
Crystal structure of Sizzled protein from Xenopus Laevis
Descriptor: Secreted Xwnt8 inhibitor sizzled
Authors:Sharma, U, Harlos, K, Hulmes, D.J.S, Aghajari, N.
Deposit date:2021-04-08
Release date:2022-09-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Dynamics of the secreted frizzled related protein Sizzled and potential implications for binding to bone morphogenetic protein-1 (BMP-1).
Sci Rep, 12, 2022

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数据于2024-06-12公开中

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