5FN8
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![BU of 5fn8 by Molmil](/molmil-images/mine/5fn8) | Crystal structure of rat CD45 extracellular region, domains d3-d4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C | Authors: | Chang, V.T, Fernandes, R.A, Ganzinger, K.A, Lee, S.F, Siebold, C, McColl, J, Jonsson, P, Palayret, M, Harlos, K, Coles, C.H, Jones, E.Y, Lui, Y, Huang, E, Gilbert, R.J.C, Klenerman, D, Aricescu, A.R, Davis, S.J. | Deposit date: | 2015-11-11 | Release date: | 2016-03-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'. Nat.Immunol., 17, 2016
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5FN7
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![BU of 5fn7 by Molmil](/molmil-images/mine/5fn7) | Crystal structure of human CD45 extracellular region, domains d1-d2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MERCURY (II) ION, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C | Authors: | Chang, V.T, Fernandes, R.A, Ganzinger, K.A, Lee, S.F, Siebold, C, McColl, J, Jonsson, P, Palayret, M, Harlos, K, Coles, C.H, Jones, E.Y, Lui, Y, Huang, E, Gilbert, R.J.C, Klenerman, D, Aricescu, A.R, Davis, S.J. | Deposit date: | 2015-11-10 | Release date: | 2016-03-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'. Nat.Immunol., 17, 2016
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2CDG
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![BU of 2cdg by Molmil](/molmil-images/mine/2cdg) | Structure and binding kinetics of three different human CD1d-alpha- Galactosylceramide-specific T cell receptors (TCR 5B) | Descriptor: | TCR 5E | Authors: | Gadola, S.D, Koch, M, Marles-Wright, J, Lissin, N.M, Sheperd, D, Matulis, G, Harlos, K, Villiger, P.M, Stuart, D.I, Jakobsen, B.K, Cerundolo, V, Jones, E.Y. | Deposit date: | 2006-01-23 | Release date: | 2006-03-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structrue and Binding Kinetics of Three Different Human Cd1D-Alpha-Galactosylceramide-Specific T Cell Receptors J.Exp.Med., 203, 2006
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2CDE
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![BU of 2cde by Molmil](/molmil-images/mine/2cde) | Structure and binding kinetics of three different human CD1d-alpha- Galactosylceramide specific T cell receptors - iNKT-TCR | Descriptor: | INKT-TCR | Authors: | Gadola, S.D, Koch, M, Marles-Wright, J, Lissin, N.M, Sheperd, D, Matulis, G, Harlos, K, Villiger, P.M, Stuart, D.I, Jakobsen, B.K, Cerundolo, V, Jones, E.Y. | Deposit date: | 2006-01-23 | Release date: | 2006-03-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structrue and Binding Kinetics of Three Different Human Cd1D-Alpha-Galactosylceramide-Specific T Cell Receptors J.Exp.Med., 203, 2006
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4QKI
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![BU of 4qki by Molmil](/molmil-images/mine/4qki) | Dimeric form of human LLT1, a ligand for NKR-P1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C-type lectin domain family 2 member D | Authors: | Skalova, T, Blaha, J, Harlos, K, Duskova, J, Koval, T, Stransky, J, Hasek, J, Vanek, O, Dohnalek, J. | Deposit date: | 2014-06-06 | Release date: | 2015-03-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Four crystal structures of human LLT1, a ligand of human NKR-P1, in varied glycosylation and oligomerization states Acta Crystallogr.,Sect.D, 71, 2015
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4QKG
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![BU of 4qkg by Molmil](/molmil-images/mine/4qkg) | Monomeric form of human LLT1, a ligand for NKR-P1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C-type lectin domain family 2 member D, SULFATE ION | Authors: | Skalova, T, Blaha, J, Harlos, K, Duskova, J, Koval, T, Stransky, J, Hasek, J, Vanek, O, Dohnalek, J. | Deposit date: | 2014-06-06 | Release date: | 2015-03-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Four crystal structures of human LLT1, a ligand of human NKR-P1, in varied glycosylation and oligomerization states Acta Crystallogr.,Sect.D, 71, 2015
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4QKH
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![BU of 4qkh by Molmil](/molmil-images/mine/4qkh) | Dimeric form of human LLT1, a ligand for NKR-P1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C-type lectin domain family 2 member D | Authors: | Skalova, T, Blaha, J, Harlos, K, Duskova, J, Koval, T, Stransky, J, Hasek, J, Vanek, O, Dohnalek, J. | Deposit date: | 2014-06-06 | Release date: | 2015-03-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Four crystal structures of human LLT1, a ligand of human NKR-P1, in varied glycosylation and oligomerization states Acta Crystallogr.,Sect.D, 71, 2015
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6QP9
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![BU of 6qp9 by Molmil](/molmil-images/mine/6qp9) | Drosophila Semaphorin 1a, extracellular domains 1-2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Semaphorin-1A | Authors: | Rozbesky, D, Robinson, R.A, Harlos, K, Siebold, C, Jones, E.Y. | Deposit date: | 2019-02-13 | Release date: | 2019-08-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning. Nat Commun, 10, 2019
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4ZEL
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![BU of 4zel by Molmil](/molmil-images/mine/4zel) | Human dopamine beta-hydroxylase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ... | Authors: | Vendelboe, T.V, Harris, P, Christensen, H.E.M, Harlos, K, Walter, T, Zhao, Y, Omari, K. | Deposit date: | 2015-04-20 | Release date: | 2016-04-20 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The crystal structure of human dopamine beta-hydroxylase at 2.9 angstrom resolution. Sci Adv, 2, 2016
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5FN6
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![BU of 5fn6 by Molmil](/molmil-images/mine/5fn6) | Crystal structure of human CD45 extracellular region, domains d1-d3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C | Authors: | Chang, V.T, Fernandes, R.A, Ganzinger, K.A, Lee, S.F, Siebold, C, McColl, J, Jonsson, P, Palayret, M, Harlos, K, Coles, C.H, Jones, E.Y, Lui, Y, Huang, E, Gilbert, R.J.C, Klenerman, D, Aricescu, A.R, Davis, S.J. | Deposit date: | 2015-11-10 | Release date: | 2016-03-23 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'. Nat.Immunol., 17, 2016
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6L3Y
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![BU of 6l3y by Molmil](/molmil-images/mine/6l3y) | Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Clado-C | Descriptor: | (3R)-3-[[(3S)-3-ethylpiperidin-1-yl]methyl]-6,8-bis(oxidanyl)-3,4-dihydroisochromen-1-one, LYSINE, Lysine--tRNA ligase, ... | Authors: | Babbar, P, Sharma, A, Mishra, S, Manickam, Y, Harlos, K. | Deposit date: | 2019-10-15 | Release date: | 2021-05-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Cladosporin inhibitor, Cla-B Chembiochem, 2021
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5OSN
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![BU of 5osn by Molmil](/molmil-images/mine/5osn) | Crystal Structure of Bovine Enterovirus 2 determined with Serial Femtosecond X-ray Crystallography | Descriptor: | Capsid protein, GLUTAMIC ACID, POTASSIUM ION, ... | Authors: | Roedig, P, Ginn, H.M, Pakendorf, T, Sutton, G, Harlos, K, Walter, T.S, Meyer, J, Fischer, P, Duman, R, Vartiainen, I, Reime, B, Warmer, M, Brewster, A.S, Young, I.D, Michels-Clark, T, Sauter, N.K, Kotecha, A, Kelly, J, Rowlands, D.J, Sikorsky, M, Nelson, S, Damiani, D.S, Alonso-Mori, R, Ren, J, Fry, E.E, David, C, Stuart, D.I, Wagner, A, Meents, A. | Deposit date: | 2017-08-17 | Release date: | 2017-08-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | High-speed fixed-target serial virus crystallography. Nat. Methods, 14, 2017
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2BRY
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![BU of 2bry by Molmil](/molmil-images/mine/2bry) | Crystal structure of the native monooxygenase domain of MICAL at 1.45 A resolution | Descriptor: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Siebold, C, Berrow, N, Walter, T.S, Harlos, K, Owens, R.J, Terman, J.R, Stuart, D.I, Kolodkin, A.L, Pasterkamp, R.J, Jones, E.Y. | Deposit date: | 2005-05-13 | Release date: | 2005-10-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | High-Resolution Structure of the Catalytic Region of Mical (Molecule Interacting with Casl), a Multidomain Flavoenzyme-Signaling Molecule. Proc.Natl.Acad.Sci.USA, 102, 2005
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2YQ2
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![BU of 2yq2 by Molmil](/molmil-images/mine/2yq2) | Structure of BVDV1 envelope glycoprotein E2, pH8 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BVDV1 E2 | Authors: | El Omari, K, Iourin, O, Harlos, K, Grimes, J.M, Stuart, D.I. | Deposit date: | 2012-11-04 | Release date: | 2013-01-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Structure of a Pestivirus Envelope Glycoprotein E2 Clarifies its Role in Cell Entry. Cell Rep., 3, 2013
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2YQ3
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![BU of 2yq3 by Molmil](/molmil-images/mine/2yq3) | Structure of BVDV1 envelope glycoprotein E2, pH5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BVDV1 E2 | Authors: | El Omari, K, Iourin, O, Harlos, K, Grimes, J.M, Stuart, D.I. | Deposit date: | 2012-11-04 | Release date: | 2013-01-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.29 Å) | Cite: | Structure of a Pestivirus Envelope Glycoprotein E2 Clarifies its Role in Cell Entry. Cell Rep., 3, 2013
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2JJW
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![BU of 2jjw by Molmil](/molmil-images/mine/2jjw) | Structure of human signal regulatory protein (sirp) gamma | Descriptor: | SIGNAL REGULATORY PROTEIN GAMMA | Authors: | Hatherley, D, Graham, S.C, Turner, J, Harlos, K, Stuart, D.I, Barclay, A.N. | Deposit date: | 2008-04-22 | Release date: | 2008-08-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47. Mol.Cell, 31, 2008
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5HNS
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![BU of 5hns by Molmil](/molmil-images/mine/5hns) | Structure of glycosylated NPC1 luminal domain C | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Niemann-Pick C1 protein, ... | Authors: | Zhao, Y, Ren, J, Harlos, K, Stuart, D.I. | Deposit date: | 2016-01-18 | Release date: | 2016-02-10 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure of glycosylated NPC1 luminal domain C reveals insights into NPC2 and Ebola virus interactions. Febs Lett., 590, 2016
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5NUZ
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![BU of 5nuz by Molmil](/molmil-images/mine/5nuz) | Junin virus GP1 glycoprotein in complex with an antibody Fab fragment | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ISOPROPYL ALCOHOL, ... | Authors: | Zeltina, A, Krumm, S.A, Sahin, M, Struwe, W.B, Harlos, K, Nunberg, J.H, Crispin, M, Pinschewer, D.D, Doores, K.J, Bowden, T.A. | Deposit date: | 2017-05-03 | Release date: | 2017-06-28 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Convergent immunological solutions to Argentine hemorrhagic fever virus neutralization. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6L4Q
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![BU of 6l4q by Molmil](/molmil-images/mine/6l4q) | Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Clado-B | Descriptor: | (3R)-3-[[(3R)-3-methylpiperidin-1-yl]methyl]-6,8-bis(oxidanyl)-3,4-dihydroisochromen-1-one, LYSINE, Lysine--tRNA ligase | Authors: | Babbar, P, Sharma, A, Manickam, Y, Mishra, S, Harlos, K. | Deposit date: | 2019-10-19 | Release date: | 2021-05-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Cladosporin inhibitor, Cla-B Chembiochem, 2021
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5J67
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![BU of 5j67 by Molmil](/molmil-images/mine/5j67) | Structure of Astrotactin-2, a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Astrotactin-2, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... | Authors: | Ni, T, Harlos, K, Gilbert, R.J.C. | Deposit date: | 2016-04-04 | Release date: | 2016-05-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.16 Å) | Cite: | Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development. Open Biology, 6, 2016
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6IPA
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![BU of 6ipa by Molmil](/molmil-images/mine/6ipa) | |
5BQE
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![BU of 5bqe by Molmil](/molmil-images/mine/5bqe) | Crystal structure of Norrin in complex with the cysteine-rich domain of Frizzled 4 -Methylated form | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Chang, T.-H, Hsieh, F.-L, Harlos, K, Jones, E.Y. | Deposit date: | 2015-05-28 | Release date: | 2015-07-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan. Elife, 4, 2015
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1AGC
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![BU of 1agc by Molmil](/molmil-images/mine/1agc) | ANTAGONIST HIV-1 GAG PEPTIDES INDUCE STRUCTURAL CHANGES IN HLA B8-HIV-1 GAG PEPTIDE (GGKKKYQL-7Q MUTATION) | Descriptor: | B*0801, BETA-2 MICROGLOBULIN, HIV-1 GAG PEPTIDE (GGKKKYQL - 7Q MUTATION) | Authors: | Reid, S.W, Mcadam, S, Smith, K.J, Klenerman, P, O'Callaghan, C.A, Harlos, K, Jakobsen, B.K, Mcmichael, A.J, Bell, J, Stuart, D.I, Jones, E.Y. | Deposit date: | 1997-03-24 | Release date: | 1997-06-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Antagonist HIV-1 Gag peptides induce structural changes in HLA B8. J.Exp.Med., 184, 1996
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1AGF
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![BU of 1agf by Molmil](/molmil-images/mine/1agf) | ANTAGONIST HIV-1 GAG PEPTIDES INDUCE STRUCTURAL CHANGES IN HLA B8-HIV-1 GAG PEPTIDE (GGKKRYKL-5R MUTATION) | Descriptor: | B*0801, BETA-2 MICROGLOBULIN, HIV-1 GAG PEPTIDE (GGKKRYKL - 5R MUTATION) | Authors: | Reid, S.W, Mcadam, S, Smith, K.J, Klenerman, P, O'Callaghan, C.A, Harlos, K, Jakobsen, B.K, Mcmichael, A.J, Bell, J, Stuart, D.I, Jones, E.Y. | Deposit date: | 1997-03-24 | Release date: | 1997-06-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Antagonist HIV-1 Gag peptides induce structural changes in HLA B8. J.Exp.Med., 184, 1996
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1AGE
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![BU of 1age by Molmil](/molmil-images/mine/1age) | ANTAGONIST HIV-1 GAG PEPTIDES INDUCE STRUCTURAL CHANGES IN HLA B8-HIV-1 GAG PEPTIDE (GGKKKYRL-7R MUTATION) | Descriptor: | B*0801, BETA-2 MICROGLOBULIN, HIV-1 GAG PEPTIDE (GGKKKYRL - 7R MUTATION) | Authors: | Reid, S.W, Mcadam, S, Smith, K.J, Klenerman, P, O'Callaghan, C.A, Harlos, K, Jakobsen, B.K, Mcmichael, A.J, Bell, J, Stuart, D.I, Jones, E.Y. | Deposit date: | 1997-03-24 | Release date: | 1997-06-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Antagonist HIV-1 Gag peptides induce structural changes in HLA B8. J.Exp.Med., 184, 1996
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