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PDB: 26 results

4NH8
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Correlation between chemotype-dependent binding conformations of HSP90 alpha/beta and isoform selectivity
Descriptor: 2-fluoro-6-[(3S)-tetrahydrofuran-3-ylamino]-4-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)benzamide, Heat shock protein HSP 90-alpha
Authors:Ernst, J.T, Zuccola, H.J.
Deposit date:2013-11-04
Release date:2014-01-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Correlation between chemotype-dependent binding conformations of HSP90 alpha / beta and isoform selectivity-Implications for the structure-based design of HSP90 alpha / beta selective inhibitors for treating neurodegenerative diseases.
Bioorg.Med.Chem.Lett., 24, 2014
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