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PDB: 2 results

7UM3
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BU of 7um3 by Molmil
Crystal structure of a Fab in complex with a peptide derived from the LAG-3 D1 domain loop insertion
Descriptor: D1 domain loop peptide from Lymphocyte activation gene 3 protein, Fab heavy chain, Fab light chain
Authors:Zorn, J.A, Lee, P.S, Rajpal, A, Strop, P.
Deposit date:2022-04-06
Release date:2022-09-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3983 Å)
Cite:Preclinical Characterization of Relatlimab, a Human LAG-3-Blocking Antibody, Alone or in Combination with Nivolumab.
Cancer Immunol Res, 10, 2022
4XUF
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BU of 4xuf by Molmil
Crystal structure of the FLT3 kinase domain bound to the inhibitor quizartinib (AC220)
Descriptor: 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-{7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl}phenyl)urea, Receptor-type tyrosine-protein kinase FLT3
Authors:Zorn, J.A, Wang, Q, Fujimura, E, Barros, T, Kuriyan, J.
Deposit date:2015-01-25
Release date:2015-04-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal Structure of the FLT3 Kinase Domain Bound to the Inhibitor Quizartinib (AC220).
Plos One, 10, 2015

226707

数据于2024-10-30公开中

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