6NIY
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![BU of 6niy by Molmil](/molmil-images/mine/6niy) | A high-resolution cryo-electron microscopy structure of a calcitonin receptor-heterotrimeric Gs protein complex | Descriptor: | Calcitonin, Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | dal Maso, E, Glukhova, A, Zhu, Y, Garcia-Nafria, J, Tate, C.G, Atanasio, S, Reynolds, C.A, Ramirez-Aportela, E, Carazo, J.-M, Hick, C.A, Furness, S.G.B, Hay, D.L, Liang, Y.-L, Miller, L.J, Christopoulos, A, Wang, M.-W, Wootten, D, Sexton, P.M. | Deposit date: | 2019-01-02 | Release date: | 2019-01-23 | Last modified: | 2020-04-08 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | The Molecular Control of Calcitonin Receptor Signaling. Acs Pharmacol Transl Sci, 2, 2019
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6NUD
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![BU of 6nud by Molmil](/molmil-images/mine/6nud) | Small conformation of ssRNA-bound CRISPR_Csm complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cms protein Csm2, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), ... | Authors: | Zhang, K, Pintilie, G, Li, S, Zhu, Y, Chiu, W, Huang, Z. | Deposit date: | 2019-01-31 | Release date: | 2019-03-13 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry. Cell Res., 29, 2019
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6NUE
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![BU of 6nue by Molmil](/molmil-images/mine/6nue) | Small conformation of apo CRISPR_Csm complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cms protein Csm2, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), ... | Authors: | Zhang, K, Pintilie, G, Li, S, Zhu, Y, Chiu, W, Huang, Z. | Deposit date: | 2019-01-31 | Release date: | 2019-03-13 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry. Cell Res., 29, 2019
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6VQV
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![BU of 6vqv by Molmil](/molmil-images/mine/6vqv) | Type I-F CRISPR-Csy complex with its inhibitor AcrF9 | Descriptor: | AcrF9, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ... | Authors: | Zhang, K, Li, S, Pintilie, G, Zhu, Y, Huang, Z, Chiu, W. | Deposit date: | 2020-02-06 | Release date: | 2020-03-11 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM. Proc.Natl.Acad.Sci.USA, 117, 2020
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6VQX
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![BU of 6vqx by Molmil](/molmil-images/mine/6vqx) | Type I-F CRISPR-Csy complex with its inhibitor AcrF6 | Descriptor: | AcrF6, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ... | Authors: | Zhang, K, Li, S, Pintilie, G, Zhu, Y, Huang, Z, Chiu, W. | Deposit date: | 2020-02-06 | Release date: | 2020-03-11 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM. Proc.Natl.Acad.Sci.USA, 117, 2020
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4QXF
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![BU of 4qxf by Molmil](/molmil-images/mine/4qxf) | crystal structure of human LGR4 and Rspo1 | Descriptor: | Leucine-rich repeat-containing G-protein coupled receptor 4, Variable lymphocyte receptor B, R-spondin-1 | Authors: | Xu, J.G, Huang, C, Zhou, Y, Zhu, Y. | Deposit date: | 2014-07-20 | Release date: | 2014-10-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | crystal structure of human LGR4 and Rspo1 TO BE PUBLISHED
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8W72
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![BU of 8w72 by Molmil](/molmil-images/mine/8w72) | |
8W6Z
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![BU of 8w6z by Molmil](/molmil-images/mine/8w6z) | Substrate-bound crystal structure of a P450 enzyme DmlH that catalyze intramolecular phenol coupling in the biosynthesis of cihanmycins | Descriptor: | (E)-3-[2-[(2R,3S)-3-[(1R)-1-aminocarbonyloxypropyl]oxiran-2-yl]phenyl]prop-2-enoic acid, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Fang, C, Zhang, L, Zhu, Y, Zhang, C. | Deposit date: | 2023-08-30 | Release date: | 2024-06-12 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Substrate-bound crystal structure of a P450 enzyme DmlH that catalyze intramolecular phenol coupling in the biosynthesis of cihanmycins To Be Published
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5COA
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![BU of 5coa by Molmil](/molmil-images/mine/5coa) | Crystal structure of iridoid synthase at 2.2-angstrom resolution | Descriptor: | HEXAETHYLENE GLYCOL, Iridoid synthase, SULFATE ION | Authors: | Qin, L, Zhu, Y, Ding, Z, Zhang, X, Ye, S, Zhang, R. | Deposit date: | 2015-07-20 | Release date: | 2016-03-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of iridoid synthase in complex with NADP(+)/8-oxogeranial reveals the structural basis of its substrate specificity. J.Struct.Biol., 194, 2016
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5COB
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![BU of 5cob by Molmil](/molmil-images/mine/5cob) | Crystal structure of iridoid synthase in complex with NADP+ and 8-oxogeranial at 2.65-angstrom resolution | Descriptor: | (2E,6E)-2,6-dimethylocta-2,6-dienedial, Iridoid synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Qin, L, Zhu, Y, Ding, Z, Zhang, X, Ye, S, Zhang, R. | Deposit date: | 2015-07-20 | Release date: | 2016-03-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structure of iridoid synthase in complex with NADP(+)/8-oxogeranial reveals the structural basis of its substrate specificity. J.Struct.Biol., 194, 2016
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8H77
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![BU of 8h77 by Molmil](/molmil-images/mine/8h77) | Hsp90-AhR-p23-XAP2 complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ... | Authors: | Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F. | Deposit date: | 2022-10-19 | Release date: | 2023-01-04 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of the cytosolic AhR complex. Structure, 31, 2023
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8K11
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![BU of 8k11 by Molmil](/molmil-images/mine/8k11) | SID1 transmembrane family member 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SID1 transmembrane family member 2 | Authors: | Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X. | Deposit date: | 2023-07-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity. Cell Res., 34, 2024
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8K12
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![BU of 8k12 by Molmil](/molmil-images/mine/8k12) | SID1 transmembrane family member 2 | Descriptor: | SID1 transmembrane family member 2 | Authors: | Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X. | Deposit date: | 2023-07-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity. Cell Res., 34, 2024
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8K1B
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![BU of 8k1b by Molmil](/molmil-images/mine/8k1b) | SID1 transmembrane family member 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SID1 transmembrane family member 1 | Authors: | Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X. | Deposit date: | 2023-07-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity. Cell Res., 34, 2024
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8K10
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![BU of 8k10 by Molmil](/molmil-images/mine/8k10) | SID1 transmembrane family member 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SID1 transmembrane family member 2 | Authors: | Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X. | Deposit date: | 2023-07-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity. Cell Res., 34, 2024
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8K13
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![BU of 8k13 by Molmil](/molmil-images/mine/8k13) | SID1 transmembrane family member 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SID1 transmembrane family member 1 | Authors: | Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X. | Deposit date: | 2023-07-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity. Cell Res., 34, 2024
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8K1D
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![BU of 8k1d by Molmil](/molmil-images/mine/8k1d) | SID1 transmembrane family member 1 | Descriptor: | SID1 transmembrane family member 1 | Authors: | Guo, H, Qi, C, Lu, Y, Yang, H, Zhu, Y, Sun, F, Ji, X. | Deposit date: | 2023-07-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.53 Å) | Cite: | Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity. Cell Res., 34, 2024
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4F7H
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![BU of 4f7h by Molmil](/molmil-images/mine/4f7h) | The crystal structure of kindlin-2 pleckstrin homology domain in free form | Descriptor: | Fermitin family homolog 2, S,R MESO-TARTARIC ACID | Authors: | Liu, Y, Zhu, Y, Qin, J, Ye, S, Zhang, R. | Deposit date: | 2012-05-16 | Release date: | 2012-06-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of kindlin-2 PH domain reveals a conformational transition for its membrane anchoring and regulation of integrin activation. Protein Cell, 3, 2012
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5GRR
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![BU of 5grr by Molmil](/molmil-images/mine/5grr) | Crystal structure of MCR-1 | Descriptor: | GLYCEROL, Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION | Authors: | Ma, G, Zhu, Y, Yu, Z, Zhang, H. | Deposit date: | 2016-08-12 | Release date: | 2017-01-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | High resolution crystal structure of the catalytic domain of MCR-1 Sci Rep, 6, 2016
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4FMD
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![BU of 4fmd by Molmil](/molmil-images/mine/4fmd) | EspG-Rab1 complex structure at 3.05 A | Descriptor: | ALUMINUM FLUORIDE, DI(HYDROXYETHYL)ETHER, EspG protein, ... | Authors: | Shao, F, Zhu, Y. | Deposit date: | 2012-06-16 | Release date: | 2012-09-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses. Cell(Cambridge,Mass.), 150, 2012
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4FMA
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![BU of 4fma by Molmil](/molmil-images/mine/4fma) | EspG structure | Descriptor: | ACETIC ACID, EspG protein, FORMIC ACID, ... | Authors: | Shao, F, Zhu, Y, Hu, L. | Deposit date: | 2012-06-16 | Release date: | 2012-09-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses. Cell(Cambridge,Mass.), 150, 2012
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4FMC
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![BU of 4fmc by Molmil](/molmil-images/mine/4fmc) | EspG-Rab1 complex | Descriptor: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Shao, F, Zhu, Y. | Deposit date: | 2012-06-16 | Release date: | 2012-09-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses. Cell(Cambridge,Mass.), 150, 2012
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4FME
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![BU of 4fme by Molmil](/molmil-images/mine/4fme) | EspG-Rab1-Arf6 complex | Descriptor: | ADP-ribosylation factor 6, ALUMINUM FLUORIDE, EspG protein, ... | Authors: | Shao, F, Zhu, Y. | Deposit date: | 2012-06-16 | Release date: | 2012-09-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses. Cell(Cambridge,Mass.), 150, 2012
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4FMB
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![BU of 4fmb by Molmil](/molmil-images/mine/4fmb) | VirA-Rab1 complex structure | Descriptor: | ALUMINUM FLUORIDE, Cysteine protease-like virA, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Shao, F, Zhu, Y. | Deposit date: | 2012-06-16 | Release date: | 2012-09-05 | Last modified: | 2012-10-03 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses. Cell(Cambridge,Mass.), 150, 2012
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4KK1
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![BU of 4kk1 by Molmil](/molmil-images/mine/4kk1) | Crystal Structure of TSC1 core domain from S. pombe | Descriptor: | Tuberous sclerosis 1 protein homolog | Authors: | Sun, W, Zhu, Y, Wang, Z.Z, Zhong, Q, Gao, F, Lou, J.Z, Gong, W.M, Xu, W.Q. | Deposit date: | 2013-05-05 | Release date: | 2013-07-17 | Last modified: | 2013-07-31 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Crystal structure of the yeast TSC1 core domain and implications for tuberous sclerosis pathological mutations. Nat Commun, 4, 2013
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