1S26
| Structure of Anthrax Edema Factor-Calmodulin-alpha,beta-methyleneadenosine 5'-triphosphate Complex Reveals an Alternative Mode of ATP Binding to the Catalytic Site | 分子名称: | CALCIUM ION, Calmodulin, Calmodulin-sensitive adenylate cyclase, ... | 著者 | Shen, Y, Zhukovskaya, N.L, Bohm, A, Tang, W.-J. | 登録日 | 2004-01-08 | 公開日 | 2004-04-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of anthrax edema factor-calmodulin-adenosine-5'-(alpha,beta-methylene)-triphosphate complex reveals an alternative mode of ATP binding to the catalytic site Biochem.Biophys.Res.Commun., 317, 2004
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1XFV
| Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP | 分子名称: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin 2, ... | 著者 | Shen, Q, Zhukovskaya, N.L, Guo, Q, Florian, J, Tang, W.J. | 登録日 | 2004-09-15 | 公開日 | 2005-05-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor. EMBO J., 24, 2005
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1XFW
| Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3'5' cyclic AMP (cAMP) | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CALCIUM ION, Calmodulin 2, ... | 著者 | Shen, Y, Zhukovskaya, N.L, Guo, Q, Florian, J, Tang, W.J. | 登録日 | 2004-09-15 | 公開日 | 2005-05-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor. EMBO J., 24, 2005
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4S2U
| Crystal structure of the Phosphorybosylpyrophosphate synthetase from E. Coli | 分子名称: | MAGNESIUM ION, Ribose-phosphate pyrophosphokinase | 著者 | Timofeev, V.I, Abramchik, Y.A, Muravieva, T.I, Iaroslavtceva, A.K, Stepanenko, V.N, Zhukhlistova, N.E, Esipov, R.S, Kuranova, I.P. | 登録日 | 2015-01-23 | 公開日 | 2016-01-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Crystal structure of the Phosphorybosylpyrophosphate synthetase from E. Coli To be Published
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8T7C
| Crystal structure of human phospholipase C gamma 2 | 分子名称: | 1,2-ETHANEDIOL, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2, CALCIUM ION | 著者 | Chen, Y, Choi, H, Zhuang, N, Hu, L, Qian, D, Wang, J. | 登録日 | 2023-06-20 | 公開日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | The crystal and cryo-EM structures of PLCg2 reveal dynamic inter-domain recognitions in autoinhibition To Be Published
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8UPW
| Structure of SARS-Cov2 3CLPro in complex with Compound 34 | 分子名称: | 3C-like proteinase nsp5, methyl {(2S)-1-[(1S,3aR,6aS)-1-{[(2R,3S,6S)-6-fluoro-2-hydroxy-1-(methylamino)-1-oxoheptan-3-yl]carbamoyl}hexahydrocyclopenta[c]pyrrol-2(1H)-yl]-3,3-dimethyl-1-oxobutan-2-yl}carbamate | 著者 | Krishnamurthy, H, Zhuang, N, Qiang, D, Wu, Y, Klein, D.J. | 登録日 | 2023-10-23 | 公開日 | 2024-03-06 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic. J.Med.Chem., 67, 2024
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8UTE
| Structure of SARS-Cov2 3CLPro in complex with Compound 27 | 分子名称: | 1,2-ETHANEDIOL, 3C-like proteinase nsp5, methyl {(2S)-1-[(1S,3aR,6aS)-1-{[(2R,3S)-6,6-difluoro-2-hydroxy-1-(methylamino)-1-oxoheptan-3-yl]carbamoyl}hexahydrocyclopenta[c]pyrrol-2(1H)-yl]-3,3-dimethyl-1-oxobutan-2-yl}carbamate | 著者 | Krishnamurthy, H, Zhuang, N, Qiang, D, Wu, Y, Klein, D.J. | 登録日 | 2023-10-31 | 公開日 | 2024-03-06 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic. J.Med.Chem., 67, 2024
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8UPV
| Structure of SARS-Cov2 3CLPro in complex with Compound 33 | 分子名称: | 3C-like proteinase nsp5, methyl {(2S)-1-[(1S,3aR,6aS)-1-{[(2R,3S,6R)-6-fluoro-2-hydroxy-1-(methylamino)-1-oxoheptan-3-yl]carbamoyl}hexahydrocyclopenta[c]pyrrol-2(1H)-yl]-3,3-dimethyl-1-oxobutan-2-yl}carbamate | 著者 | Krishnamurthy, H, Zhuang, N, Qiang, D, Wu, Y, Klein, D.J. | 登録日 | 2023-10-23 | 公開日 | 2024-03-06 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic. J.Med.Chem., 67, 2024
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4IRB
| Crystal Structure of Vaccinia Virus Uracil DNA Glycosylase Mutant del171-172D4 | 分子名称: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | 著者 | Schormann, N, Zhukovskaya, N, Sartmatova, D, Nuth, M, Ricciardi, R.P, Chattopadhyay, D. | 登録日 | 2013-01-14 | 公開日 | 2014-02-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Mutations at the dimer interface affect both function and structure of the Vaccinia virus uracil DNA glycosylase To be Published
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3QN0
| Structure of 6-pyruvoyltetrahydropterin synthase | 分子名称: | 6-carboxy-5,6,7,8-tetrahydropterin synthase, ZINC ION | 著者 | Seo, K.H, Zhuang, N.N, Lee, K.H. | 登録日 | 2011-02-07 | 公開日 | 2011-12-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Structural basis of a novel activity of bacterial 6-pyruvoyltetrahydropterin synthase homologues distinct from mammalian 6-pyruvoyltetrahydropterin synthase activity. Acta Crystallogr.,Sect.D, 70, 2014
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3QN9
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3QNA
| Crystal structure of a 6-pyruvoyltetrahydropterin synthase homologue from Esherichia coli complexed sepiapterin | 分子名称: | 6-carboxy-5,6,7,8-tetrahydropterin synthase, BIOPTERIN, ZINC ION | 著者 | Seo, K.H, Zhuang, N.N, Lee, K.H. | 登録日 | 2011-02-08 | 公開日 | 2011-12-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis of a novel activity of bacterial 6-pyruvoyltetrahydropterin synthase homologues distinct from mammalian 6-pyruvoyltetrahydropterin synthase activity. Acta Crystallogr.,Sect.D, 70, 2014
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3TWO
| The crystal structure of CAD from Helicobacter pylori complexed with NADP(H) | 分子名称: | Mannitol dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ZINC ION | 著者 | Seo, K.H, Zhuang, N.N, Cong, C, Lee, K.H. | 登録日 | 2011-09-22 | 公開日 | 2011-10-12 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Unusual NADPH conformation in the crystal structure of a cinnamyl alcohol dehydrogenase from Helicobacter pylori in complex with NADP(H) and substrate docking analysis Febs Lett., 586, 2012
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