6PLQ
| CryoEM structure of zebra fish alpha-1 glycine receptor YGF mutant bound with GABA in SMA, super-open state | 分子名称: | GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Yu, J, Zhu, H, Gouaux, E. | 登録日 | 2019-07-01 | 公開日 | 2021-02-10 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor. Cell, 184, 2021
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6PM3
| CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, closed state | 分子名称: | 2-AMINOETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1 | 著者 | Yu, J, Zhu, H, Gouaux, E. | 登録日 | 2019-07-01 | 公開日 | 2021-02-10 | 最終更新日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor. Cell, 184, 2021
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6PM1
| CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, desensitized state | 分子名称: | 2-AMINOETHANESULFONIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Yu, J, Zhu, H, Gouaux, E. | 登録日 | 2019-07-01 | 公開日 | 2021-02-10 | 最終更新日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor. Cell, 184, 2021
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6PM5
| CryoEM structure of zebra fish alpha-1 glycine receptor bound with Glycine in SMA, desensitized state | 分子名称: | GLYCINE, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Yu, J, Zhu, H, Gouaux, E. | 登録日 | 2019-07-01 | 公開日 | 2021-02-10 | 最終更新日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor. Cell, 184, 2021
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6PM4
| CryoEM structure of zebra fish alpha-1 glycine receptor bound with Glycine in SMA, super-open state | 分子名称: | GLYCINE, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Yu, J, Zhu, H, Gouaux, E. | 登録日 | 2019-07-01 | 公開日 | 2021-02-10 | 最終更新日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor. Cell, 184, 2021
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6PM2
| CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, open state | 分子名称: | 2-AMINOETHANESULFONIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Yu, J, Zhu, H, Gouaux, E. | 登録日 | 2019-07-01 | 公開日 | 2021-02-10 | 最終更新日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor. Cell, 184, 2021
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6PLP
| CryoEM structure of zebra fish alpha-1 glycine receptor YGF mutant bound with GABA in SMA, desensitized state | 分子名称: | GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Yu, J, Zhu, H, Gouaux, E. | 登録日 | 2019-07-01 | 公開日 | 2021-02-10 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor. Cell, 184, 2021
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6PM6
| CryoEM structure of zebra fish alpha-1 glycine receptor bound with Glycine in SMA, open state | 分子名称: | GLYCINE, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Yu, J, Zhu, H, Gouaux, E. | 登録日 | 2019-07-01 | 公開日 | 2021-02-10 | 最終更新日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor. Cell, 184, 2021
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6PLW
| CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in SMA, super-open state | 分子名称: | GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Yu, J, Zhu, H, Gouaux, E. | 登録日 | 2019-07-01 | 公開日 | 2021-02-10 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor. Cell, 184, 2021
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5FZR
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8IT1
| Cryo-EM structure of Crt-SPARTA-gRNA-tDNA tetramer (NADase active form) | 分子名称: | DNA (45-mer), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*U)-3'), ... | 著者 | Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S. | 登録日 | 2023-03-21 | 公開日 | 2023-11-08 | 最終更新日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | 主引用文献 | Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute. Nature, 625, 2024
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7KRS
| Structural impact on SARS-CoV-2 spike protein by D614G substitution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, J, Cai, Y.F, Xiao, T.S, Lu, J.M, Peng, H.Q, Sterling, S.M, Walsh Jr, R.M, Volloch, S.R, Zhu, H.S, Woosley, A.N, Yang, W, Sliz, P, Chen, B. | 登録日 | 2020-11-20 | 公開日 | 2021-03-24 | 最終更新日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural impact on SARS-CoV-2 spike protein by D614G substitution. Science, 372, 2021
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8EFK
| Structure of Lates calcarifer DNA polymerase theta polymerase domain with hairpin DNA | 分子名称: | 2',3'-dideoxyadenosine triphosphate, DNA (5'-D(P*TP*TP*TP*TP*GP*GP*CP*TP*TP*TP*TP*GP*CP*CP*(2DA))-3'), Lates calcarifer DNA polymerase theta, ... | 著者 | Li, C, Zhu, H, Sun, J, Gao, Y. | 登録日 | 2022-09-08 | 公開日 | 2022-12-14 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis of DNA polymerase theta mediated DNA end joining. Nucleic Acids Res., 51, 2023
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8EF9
| Structure of Lates calcarifer DNA polymerase theta polymerase domain with long duplex DNA, complex Ia | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*AP*TP*CP*CP*GP*TP*AP*GP*(2DA))-3'), DNA (5'-D(*AP*GP*CP*TP*CP*TP*AP*CP*GP*GP*AP*TP*GP*C)-3'), ... | 著者 | Li, C, Zhu, H, Sun, J, Gao, Y. | 登録日 | 2022-09-08 | 公開日 | 2022-12-14 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structural basis of DNA polymerase theta mediated DNA end joining. Nucleic Acids Res., 51, 2023
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8EFC
| Structure of Lates calcarifer DNA polymerase theta polymerase domain with long duplex DNA, complex Ia | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*CP*TP*GP*TP*GP*AP*GP*GP*CP*AP*TP*CP*CP*GP*TP*AP*GP*(2DA))-3'), DNA (5'-D(*AP*GP*CP*TP*CP*TP*AP*CP*GP*GP*AP*TP*GP*CP*CP*TP*CP*AP*CP*AP*G)-3'), ... | 著者 | Li, C, Zhu, H, Sun, J, Gao, Y. | 登録日 | 2022-09-08 | 公開日 | 2022-12-14 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis of DNA polymerase theta mediated DNA end joining. Nucleic Acids Res., 51, 2023
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8K9G
| Cryo-EM structure of Crt-SPARTA-gRNA-tDNA dimer (conformation-1) | 分子名称: | DNA (45-mer), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*U)-3'), ... | 著者 | Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S. | 登録日 | 2023-08-01 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute. Nature, 625, 2024
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7KRR
| Structural impact on SARS-CoV-2 spike protein by D614G substitution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, J, Cai, Y.F, Xiao, T.S, Lu, J.M, Peng, H.Q, Sterling, S.M, Walsh Jr, R.M, Volloch, S.R, Zhu, H.S, Woosley, A.N, Yang, W, Sliz, P, Chen, B. | 登録日 | 2020-11-20 | 公開日 | 2021-03-24 | 最終更新日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural impact on SARS-CoV-2 spike protein by D614G substitution. Science, 372, 2021
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7KRQ
| Structural impact on SARS-CoV-2 spike protein by D614G substitution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, J, Cai, Y.F, Xiao, T.S, Lu, J.M, Peng, H.Q, Sterling, S.M, Walsh Jr, R.M, Volloch, S.R, Zhu, H.S, Woosley, A.N, Yang, W, Sliz, P, Chen, B. | 登録日 | 2020-11-20 | 公開日 | 2021-03-31 | 最終更新日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | 主引用文献 | Structural impact on SARS-CoV-2 spike protein by D614G substitution. Science, 372, 2021
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6QF8
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6QFP
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6QH2
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5HSI
| Crystal structure of tyrosine decarboxylase at 1.73 Angstroms resolution | 分子名称: | MAGNESIUM ION, Putative decarboxylase | 著者 | Ni, Y, Zhou, J, Zhu, H, Zhang, K. | 登録日 | 2016-01-25 | 公開日 | 2016-09-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.732 Å) | 主引用文献 | Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding Sci Rep, 6, 2016
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5FZS
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8SMC
| Cryo-EM structure of LRRK2 bound with type-I inhibitor DNL201 | 分子名称: | 2-methyl-2-(3-methyl-4-{[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1H-pyrazol-1-yl)propanenitrile, GUANOSINE-5'-DIPHOSPHATE, non-specific serine/threonine protein kinase | 著者 | Sun, J, Zhu, H. | 登録日 | 2023-04-26 | 公開日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (4.02 Å) | 主引用文献 | Rab29-dependent asymmetrical activation of leucine-rich repeat kinase 2. Science, 382, 2023
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6N5V
| Crystal Structure of Strictosidine in complex with 1H-indole-4-ethanamine | 分子名称: | 2-(1H-indol-4-yl)ethan-1-amine, Strictosidine synthase | 著者 | Cai, Y, Shao, N, Xie, H, Futamura, Y, Panjikar, S, Liu, H, Zhu, H, Osada, H, Zou, H. | 登録日 | 2018-11-22 | 公開日 | 2019-11-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.549 Å) | 主引用文献 | Crystal Structure of Strictosidine in complex with 1H-indole-4-ethanamine to be published
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