3WGI
 
 | | Crystal structure of RSP in complex with beta-NAD+ and operator DNA | | 分子名称: | DNA (5'-D(*TP*AP*GP*AP*TP*TP*GP*TP*TP*AP*AP*TP*CP*GP*AP*TP*TP*AP*AP*CP*AP*AP*TP*C)-3'), NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), Redox-sensing transcriptional repressor rex | | 著者 | Zheng, Y, Ko, T.-P, Guo, R.-T. | | 登録日 | 2013-08-05 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Distinct structural features of Rex-family repressors to sense redox levels in anaerobes and aerobes.
J.Struct.Biol., 188, 2014
|
|
3WG9
 | |
4YIA
 | |
7ULX
 | | Human DDAH1 soaked with its inhibitor N4-(4-chloropyridin-2-yl)-L-asparagine | | 分子名称: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, N-(pyridin-2-yl)-L-asparagine | | 著者 | Zheng, Y, Butrin, A, Tuley, A, Liu, D, Fast, W. | | 登録日 | 2022-04-05 | | 公開日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.707 Å) | | 主引用文献 | Optimization of a switchable electrophile fragment into a potent and selective covalent inhibitor of human DDAH1
To Be Published
|
|
7ULV
 | | Human DDAH1 soaked with its inactivator S-((4-chloropyridin-2-yl)methyl)-L-cysteine | | 分子名称: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, S-[(pyridin-2-yl)methyl]-L-cysteine | | 著者 | Zheng, Y, Butrin, A, Tuley, A, Liu, D, Fast, W. | | 登録日 | 2022-04-05 | | 公開日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Optimization of a switchable electrophile fragment into a potent and selective covalent inhibitor of human DDAH1
To Be Published
|
|
7BWP
 | | Crystal complex of endo-deglycosylated PcHNL5 with (R)-mandelonitrile | | 分子名称: | (2R)-hydroxy(phenyl)ethanenitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Zheng, Y.C, Li, F.L, Yu, H.L, Xu, J.H. | | 登録日 | 2020-04-15 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | | 主引用文献 | Structure-Guided Tuning of a Hydroxynitrile Lyase to Accept Rigid Pharmaco Aldehydes.
Acs Catalysis, 2020
|
|
6JBY
 | | Crystal structure of endo-deglycosylated hydroxynitrile lyase isozyme 5 of Prunus communis | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Zheng, Y.C, Li, F.L, Yu, H.L, Xu, J.H. | | 登録日 | 2019-01-27 | | 公開日 | 2020-04-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure-Guided Tuning of a Hydroxynitrile Lyase to Accept Rigid Pharmaco Aldehydes.
Acs Catalysis, 2020
|
|
6LQY
 | | Crystal complex of endo-deglycosylated hydroxynitrile lyase isozyme 5 of Prunus communis with benzaldehyde | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, PREDICTED: (R)-mandelonitrile lyase, ... | | 著者 | Zheng, Y.C, Li, F.L, Yu, H.L, Xu, J.H. | | 登録日 | 2020-01-15 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.598 Å) | | 主引用文献 | Structure-Guided Tuning of a Hydroxynitrile Lyase to Accept Rigid Pharmaco Aldehydes.
Acs Catalysis, 2020
|
|
7TWM
 | |
7TWL
 | |
7TWK
 | |
7U58
 | |
4UC1
 | | High resolution crystal structure of translocator protein 18kDa (TSPO) from Rhodobacter sphaeroides (A139T Mutant) in C2 space group | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-1-(hexadecanoyloxy)-3-hydroxypropan-2-yl (11Z)-octadec-11-enoate, METHOXY-ETHOXYL, ... | | 著者 | Li, F, Liu, J, Zheng, Y, Garavito, R.M, Ferguson-Miller, S. | | 登録日 | 2014-08-13 | | 公開日 | 2015-02-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism.
Science, 347, 2015
|
|
7OUO
 | | Crystal structure of RNA duplex [UCGUGCGA]2 in complex with Ba2+ cation | | 分子名称: | BARIUM ION, RNA (5'-R(*UP*CP*GP*UP*GP*CP*GP*A)-3') | | 著者 | Ruszkowski, M, Mao, S, Zheng, Y.Y, Ruszkowska, A, Sheng, J. | | 登録日 | 2021-06-12 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.212 Å) | | 主引用文献 | Structural Insights Into the 5'UG/3'GU Wobble Tandem in Complex With Ba 2+ Cation.
Front Mol Biosci, 8, 2021
|
|
4RWS
 | | Crystal structure of CXCR4 and viral chemokine antagonist vMIP-II complex (PSI Community Target) | | 分子名称: | C-X-C chemokine receptor type 4/Endolysin chimeric protein, Viral macrophage inflammatory protein 2 | | 著者 | Qin, L, Kufareva, I, Holden, L, Wang, C, Zheng, Y, Wu, H, Fenalti, G, Han, G.W, Cherezov, V, Abagyan, R, Stevens, R.C, Handel, T.M, GPCR Network (GPCR) | | 登録日 | 2014-12-05 | | 公開日 | 2015-02-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine.
Science, 347, 2015
|
|
4UC3
 | | Translocator protein 18 kDa (TSPO) from Rhodobacter sphaeroides wild type | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, TRANSLOCATOR PROTEIN TSPO | | 著者 | Li, F, Liu, J, Zheng, Y, Garavito, R.M, Ferguson-Miller, S. | | 登録日 | 2014-08-13 | | 公開日 | 2015-02-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism.
Science, 347, 2015
|
|
4UC2
 | | Crystal structure of translocator protein 18kDa (TSPO) from rhodobacter sphaeroides (A139T mutant) in P212121 space group | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, TETRAETHYLENE GLYCOL, TRANSLOCATOR PROTEIN TSPO | | 著者 | Li, F, Liu, J, Zheng, Y, Garavito, R.M, Ferguson-Miller, S. | | 登録日 | 2014-08-13 | | 公開日 | 2015-02-04 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism.
Science, 347, 2015
|
|
1F7C
 | | CRYSTAL STRUCTURE OF THE BH DOMAIN FROM GRAF, THE GTPASE REGULATOR ASSOCIATED WITH FOCAL ADHESION KINASE | | 分子名称: | RHOGAP PROTEIN | | 著者 | Longenecker, K.L, Derewenda, U, Sheffield, P.J, Zheng, Y, Derewenda, Z.S. | | 登録日 | 2000-06-26 | | 公開日 | 2000-12-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of the BH domain from graf and its implications for Rho GTPase recognition.
J.Biol.Chem., 275, 2000
|
|
5MKV
 | | Crystal Structure of Human Dihydropyrimidinease-like 2 (DPYSL2A)/Collapsin Response Mediator Protein (CRMP2) residues 13-516 | | 分子名称: | 1,2-ETHANEDIOL, Dihydropyrimidinase-related protein 2 | | 著者 | Sethi, R, Zheng, Y, Krojer, T, Velupillai, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Ahmed, A.A, von Delft, F. | | 登録日 | 2016-12-05 | | 公開日 | 2017-02-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.
Nat Commun, 9, 2018
|
|
3AXE
 | | The truncated Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase V18Y/W203Y in complex with cellotetraose (cellobiose density was observed) | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucanase, CALCIUM ION, ... | | 著者 | Huang, J.W, Cheng, Y.S, Ko, T.P, Lin, C.Y, Lai, H.L, Chen, C.C, Ma, Y, Huang, C.H, Zheng, Y, Liu, J.R, Guo, R.T. | | 登録日 | 2011-04-04 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Rational design to improve thermostability and specific activity of the truncated Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase
Appl.Microbiol.Biotechnol., 94, 2012
|
|
3AXD
 | | The truncated Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase V18Y/W203Y in apo-form | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucanase, CALCIUM ION | | 著者 | Huang, J.W, Cheng, Y.S, Ko, T.P, Lin, C.Y, Lai, H.L, Chen, C.C, Ma, Y, Huang, C.H, Zheng, Y, Liu, J.R, Guo, R.T. | | 登録日 | 2011-04-03 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Rational design to improve thermostability and specific activity of the truncated Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase
Appl.Microbiol.Biotechnol., 94, 2012
|
|
4XLY
 | | The complex structure of KS-D75C with substrate CPP | | 分子名称: | (2E)-3-methyl-5-[(1R,4aR,8aR)-5,5,8a-trimethyl-2-methylidenedecahydronaphthalen-1-yl]pent-2-en-1-yl trihydrogen diphosphate, Uncharacterized protein blr2150 | | 著者 | Hu, Y, Zheng, Y, Ko, T.P, Liu, W, Guo, R.T. | | 登録日 | 2015-01-14 | | 公開日 | 2015-02-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum.
Sci Rep, 4, 2014
|
|
5MLE
 | | Crystal Structure of Human Dihydropyrimidinease-like 2 (DPYSL2A)/Collapsin Response Mediator Protein (CRMP2 13-516) Mutant Y479E/Y499E | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Dihydropyrimidinase-related protein 2, ... | | 著者 | Sethi, R, Zheng, Y, Talon, R, Velupillai, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Ahmed, A.A, von Delft, F. | | 登録日 | 2016-12-06 | | 公開日 | 2017-02-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.
Nat Commun, 9, 2018
|
|
4W4R
 | | Crystal structure of ent-kaurene synthase BJKS from bradyrhizobium japonicum | | 分子名称: | Uncharacterized protein blr2150 | | 著者 | Liu, W, Zheng, Y, Huang, C.H, Ko, T.P, Guo, R.T. | | 登録日 | 2014-08-15 | | 公開日 | 2015-01-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum.
Sci Rep, 4, 2014
|
|
4W4S
 | | Crystal structure of ent-kaurene synthase BJKS from bradyrhizobium japonicum in complex with BPH-629 | | 分子名称: | Uncharacterized protein blr2150, [2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID | | 著者 | Liu, W, Zheng, Y, Huang, C.H, Guo, R.T. | | 登録日 | 2014-08-15 | | 公開日 | 2015-01-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum.
Sci Rep, 4, 2014
|
|
