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PDB: 173 件

3LC6
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The alternative conformation structure of isocitrate dehydrogenase kinase/phosphatase from E. Coli
分子名称: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Isocitrate dehydrogenase kinase/phosphatase, ...
著者Zheng, J, Jia, Z.
登録日2010-01-09
公開日2010-04-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of the bifunctional isocitrate dehydrogenase kinase/phosphatase.
Nature, 465, 2010
3MJV
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Structure of A-type Ketoreductases from Modular Polyketide Synthase
分子名称: AmphB, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T.
登録日2010-04-13
公開日2010-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
3MJE
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Structure of A-type Ketoreductases from Modular Polyketide Synthase
分子名称: AmphB, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T.
登録日2010-04-12
公開日2010-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
3MJT
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Structure of A-type Ketoreductases from Modular Polyketide Synthase
分子名称: AmphB, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T.
登録日2010-04-13
公開日2010-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
3MJC
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Structure of A-type Ketoreductases from Modular Polyketide Synthase
分子名称: AmphB, GLYCEROL
著者Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T.
登録日2010-04-12
公開日2010-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
3FRQ
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Structure of the macrolide biosensor protein, MphR(A), with erythromcyin
分子名称: CHLORIDE ION, ERYTHROMYCIN A, GLYCEROL, ...
著者Zheng, J, Sagar, V, Smolinsky, A, Bourke, C, LaRonde-LeBlanc, N, Cropp, T.A.
登録日2009-01-08
公開日2009-03-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structure and function of the macrolide biosensor protein, MphR(A), with and without erythromycin
J.Mol.Biol., 387, 2009
3G56
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Structure of the macrolide biosensor protein, MphR(A)
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Regulator of macrolide 2'-phosphotransferase I
著者Zheng, J, Sagar, V, Smolinsky, A, Bourke, C, LaRonde-LeBlanc, N, Cropp, T.A.
登録日2009-02-04
公開日2009-03-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and function of the macrolide biosensor protein, MphR(A), with and without erythromycin
J.Mol.Biol., 387, 2009
3EPS
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The crystal structure of isocitrate dehydrogenase kinase/phosphatase from E. coli
分子名称: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Isocitrate dehydrogenase kinase/phosphatase, ...
著者Zheng, J, Jia, Z, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2008-09-29
公開日2010-04-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the bifunctional isocitrate dehydrogenase kinase/phosphatase.
Nature, 465, 2010
8XAR
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Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with SAM and Compound 54
分子名称: 1,2-ETHANEDIOL, 7-chloranyl-2-ethyl-5-pyridin-3-yl-pyrazolo[3,4-c]quinolin-4-one, CHLORIDE ION, ...
著者Zheng, J.Y, Zhang, G.P, Li, J.J, Tong, S.L.
登録日2023-12-05
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with High Selectivity, Brain Penetration, and In Vivo Efficacy.
J.Med.Chem., 67, 2024
3QP9
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The Structure of a C2-type Ketoreductase from a Modular Polyketide Synthase
分子名称: Type I polyketide synthase PikAII
著者Zheng, J, Keatinge-Clay, A.T.
登録日2011-02-11
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structural and functional analysis of c2-type ketoreductases from modular polyketide synthases.
J.Mol.Biol., 410, 2011
4IMP
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The missing linker: a dimerization motif located within polyketide synthase modules
分子名称: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Polyketide synthase extender modules 3-4
著者Zheng, J, Keatinge-Clay, A.T.
登録日2013-01-03
公開日2013-03-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献The missing linker: a dimerization motif located within polyketide synthase modules.
Acs Chem.Biol., 8, 2013
4J1S
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Crystal structure of a ketoreductase domain from the bacillaene assembly line
分子名称: Polyketide synthase PksJ
著者Zheng, J, Keatinge-Clay, A.T.
登録日2013-02-01
公開日2014-03-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structural and functional studies of a trans-acyltransferase polyketide assembly line enzyme that catalyzes stereoselective alpha- and beta-ketoreduction.
Proteins, 82, 2014
4J1Q
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Crystal structure of a ketoreductase domain from the bacillaene assembly line
分子名称: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Polyketide synthase PksJ
著者Zheng, J, Keatinge-Clay, A.T.
登録日2013-02-01
公開日2014-03-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural and functional studies of a trans-acyltransferase polyketide assembly line enzyme that catalyzes stereoselective alpha- and beta-ketoreduction.
Proteins, 82, 2014
6NKO
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Crystal structure of ForH
分子名称: ForH
著者Zheng, J, Irani, S, Zhang, Y.
登録日2019-01-07
公開日2019-04-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.403 Å)
主引用文献Identification of the Formycin A Biosynthetic Gene Cluster from Streptomyces kaniharaensis Illustrates the Interplay between Biological Pyrazolopyrimidine Formation and de Novo Purine Biosynthesis.
J. Am. Chem. Soc., 141, 2019
4L4X
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An A2-type ketoreductase from a modular polyketide synthase
分子名称: AmphI, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zheng, J, Keatinge-Clay, A.T.
登録日2013-06-10
公開日2013-06-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural Studies of an A2-Type Modular Polyketide Synthase Ketoreductase Reveal Features Controlling alpha-Substituent Stereochemistry.
Acs Chem.Biol., 8, 2013
7VWA
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BU of 7vwa by Molmil
Helicoverpa armigera pheromone-binding protein PBP1 with Z-9-hexadecenal
分子名称: (Z)-hexadec-9-enal, PBP1
著者Zheng, J, Chen, Z.
登録日2021-11-10
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Insights into the Ligand-Binding and -Releasing Mechanism of Helicoverpa armigera Pheromone-Binding Protein PBP1.
Int J Mol Sci, 23, 2022
7VW8
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Helicoverpa armigera pheromone-binding protein PBP1 at pH 7.5
分子名称: PBP1
著者Zheng, J, Chen, Z.
登録日2021-11-09
公開日2022-02-02
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural Insights into the Ligand-Binding and -Releasing Mechanism of Helicoverpa armigera Pheromone-Binding Protein PBP1.
Int J Mol Sci, 23, 2022
7VW9
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Helicoverpa armigera pheromone-binding protein PBP1 at pH 5.5
分子名称: PBP1
著者Zheng, J, Chen, Z.
登録日2021-11-10
公開日2022-02-02
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural Insights into the Ligand-Binding and -Releasing Mechanism of Helicoverpa armigera Pheromone-Binding Protein PBP1.
Int J Mol Sci, 23, 2022
7W7P
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BU of 7w7p by Molmil
Cryo-EM structure of gMCM8/9 helicase
分子名称: DNA helicase MCM8, DNA helicase MCM9
著者Zheng, J.F, Weng, Z.F, Liu, Y.F.
登録日2021-12-06
公開日2023-05-24
最終更新日2023-12-06
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Structural and mechanistic insights into the MCM8/9 helicase complex.
Elife, 12, 2023
7X2R
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Crystal structure of the E. coli transcription termination factor Rho
分子名称: Transcription termination factor Rho
著者Zheng, J, Wang, B.
登録日2022-02-26
公開日2022-04-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (4.4 Å)
主引用文献E. coli transcription termination factor Rho
To Be Published
7XFF
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BU of 7xff by Molmil
Polysaccharide export protein Wza
分子名称: Polysaccharide export protein
著者Zheng, J, Wang, B.
登録日2022-04-01
公開日2022-05-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Polysaccharide export protein Wza
To Be Published
7XFD
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Polysaccharide export protein Wza
分子名称: Polysaccharide export protein
著者Zheng, J, Wang, B.
登録日2022-04-01
公開日2022-05-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献polysaccharide export protein Wza
To Be Published
4V0R
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DENGUE VIRUS FULL LENGTH NS5 COMPLEXED WITH GTP AND SAH
分子名称: FORMIC ACID, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Zhao, Y, Soh, S, Zheng, J, Phoo, W.W, Swaminathan, K, Cornvik, T.C, Lim, S.P, Shi, P.-Y, Lescar, J, Vasudevan, S.G, Luo, D.
登録日2014-09-18
公開日2015-01-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Crystal Structure of the Dengue Virus Ns5 Protein Reveals a Novel Inter-Domain Interface Essential for Protein Flexibility and Virus Replication.
Plos Pathog., 11, 2015
1CTP
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STRUCTURE OF THE MAMMALIAN CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE AND AN INHIBITOR PEPTIDE DISPLAYS AN OPEN CONFORMATION
分子名称: MYRISTIC ACID, cAMP-DEPENDENT PROTEIN KINASE, cAMP-dependent protein kinase inhibitor, ...
著者Karlsson, R, Zheng, J, Xuong, N.H, Taylor, S.S, Sowadski, J.M.
登録日1993-04-08
公開日1994-01-31
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of the mammalian catalytic subunit of cAMP-dependent protein kinase and an inhibitor peptide displays an open conformation.
Acta Crystallogr.,Sect.D, 49, 1993
6CKV
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Solution NMR structure of human BOK
分子名称: Bcl-2-related ovarian killer protein
著者Grace, C.R, Zheng, J, Moldoveanu, T.
登録日2018-03-01
公開日2018-05-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Intrinsic Instability of BOK Enables Membrane Permeabilization in Apoptosis.
Cell Rep, 23, 2018

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件を2024-10-30に公開中

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