8DCK
 
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6IK4
 | | A Novel M23 Metalloprotease Pseudoalterin from Deep-sea | | 分子名称: | Elastinolytic metalloprotease, GLYCEROL, ZINC ION | | 著者 | Zhao, H.L, Tang, B.L, Yang, J, Chen, X.L, Zhang, Y.Z. | | 登録日 | 2018-10-14 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A predator-prey interaction between a marine Pseudoalteromonas sp. and Gram-positive bacteria.
Nat Commun, 11, 2020
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6VWS
 | | Hexamer of Helical HIV capsid by RASTR method | | 分子名称: | HIV capsid protein | | 著者 | Zhao, H, Iqbal, N, Asturias, F, Kvaratskhelia, M, Vanblerkom, P. | | 登録日 | 2020-02-20 | | 公開日 | 2020-10-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (6.08 Å) | | 主引用文献 | Structural and mechanistic bases for a potent HIV-1 capsid inhibitor.
Science, 370, 2020
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8SNL
 | | Structure of human ADAM17/iRhom2 sheddase complex | | 分子名称: | CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 17, Inactive rhomboid protein 2, ... | | 著者 | Zhao, H, Dai, Y, Wang, Y, Lee, C.H. | | 登録日 | 2023-04-27 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | | 主引用文献 | Structure of human ADAM17/iRhom2 sheddase complex
To Be Published
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8SNN
 | | Structure of mature human ADAM17/iRhom2 sheddase complex, conformation 1 | | 分子名称: | CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 17, Inactive rhomboid protein 2 | | 著者 | Zhao, H, Dai, Y, Wang, Y, Lee, C.H. | | 登録日 | 2023-04-27 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.32 Å) | | 主引用文献 | Structure of mature human ADAM17/iRhom2 sheddase complex, conformation 1
To Be Published
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8SNO
 | | Structure of mature human ADAM17/iRhom2 sheddase complex, conformation 2 | | 分子名称: | CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 17, Inactive rhomboid protein 2 | | 著者 | Zhao, H, Dai, Y, Wang, Y, Lee, C.H. | | 登録日 | 2023-04-27 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | | 主引用文献 | Structure of mature human ADAM17/iRhom2 sheddase complex, conformation 2
To Be Published
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8SNM
 | | Structure of mature human ADAM17/iRhom2 sheddase complex in complex with ADAM17 prodomain | | 分子名称: | CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 17, Disintegrin and metalloproteinase domain-containing protein 17 propeptide, ... | | 著者 | Zhao, H, Dai, Y, Wang, Y, Lee, C.H. | | 登録日 | 2023-04-27 | | 公開日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.84 Å) | | 主引用文献 | Structure of mature human ADAM17/iRhom2 sheddase complex in complex with ADAM17 prodomain
To Be Published
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5L35
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8T1I
 | | Atomic model of the mammalian Mediator complex with MED26 subunit | | 分子名称: | Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... | | 著者 | Zhao, H, Asturias, F. | | 登録日 | 2023-06-02 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (4.68 Å) | | 主引用文献 | An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II.
Mol.Cell, 84, 2024
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8T1L
 | | Atomic model of the mammalian mouse Mediator complex with CKM module | | 分子名称: | Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... | | 著者 | Zhao, H, Asturias, F. | | 登録日 | 2023-06-02 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (4.83 Å) | | 主引用文献 | A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers.
To Be Published
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4DZP
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5C15
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5C12
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5C2F
 | | K428A mutant nuclease domain of the large terminase subunit gp2 of bacterial virus Sf6 with Manganese and beta-thujaplicinol | | 分子名称: | 2,7-dihydroxy-4-(propan-2-yl)cyclohepta-2,4,6-trien-1-one, Gene 2 protein, MANGANESE (II) ION | | 著者 | Zhao, H, Tang, L. | | 登録日 | 2015-06-15 | | 公開日 | 2015-10-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism.
Nucleic Acids Res., 43, 2015
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5C10
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5C2D
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1BK9
 | | PHOSPHOLIPASE A2 MODIFIED BY PBPB | | 分子名称: | 1,4-BUTANEDIOL, CALCIUM ION, PHOSPHOLIPASE A2, ... | | 著者 | Zhao, H, Tang, L, Wang, X, Lin, Z, Zhou, Y. | | 登録日 | 1998-07-16 | | 公開日 | 1999-03-02 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of a snake venom phospholipase A2 modified by p-bromo-phenacyl-bromide.
Toxicon, 36, 1998
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3NB3
 | | The host outer membrane proteins OmpA and OmpC are packed at specific sites in the Shigella phage Sf6 virion as structural components | | 分子名称: | Outer membrane protein A, Outer membrane protein C | | 著者 | Zhao, H, Sequeira, R.D, Galeva, N.A, Tang, L. | | 登録日 | 2010-06-02 | | 公開日 | 2011-02-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (19 Å) | | 主引用文献 | The host outer membrane proteins OmpA and OmpC are associated with the Shigella phage Sf6 virion.
Virology, 409, 2011
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1XBO
 | | PTP1B complexed with Isoxazole Carboxylic Acid | | 分子名称: | 5-(3-{3-[3-HYDROXY-2-(METHOXYCARBONYL)PHENOXY]PROPENYL}PHENYL)-4-(HYDROXYMETHYL)ISOXAZOLE-3-CARBOXYLIC ACID, Protein-tyrosine phosphatase, non-receptor type 1 | | 著者 | Zhao, H, Liu, G, Xin, Z, Serby, M, Pei, Z, Szczepankiewicz, B.G, Hajduk, P.J, Abad-Zapatero, C, Hutchins, C.W, Lubben, T.H, Ballaron, S.J, Hassach, D.L, Kaszubska, W, Rondinone, C.M, Trevillyan, J.M, Jirousek, M.R. | | 登録日 | 2004-08-31 | | 公開日 | 2004-10-19 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors.
Bioorg.Med.Chem.Lett., 14, 2004
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8XK8
 | | N1D10 Fab bound to SFTSV glycoprotein-Gn | | 分子名称: | Envelopment polyprotein, mAb N1D10 Fab heavy chain, mAb N1D10 Fab light chain | | 著者 | Zhao, H, Deng, Z. | | 登録日 | 2023-12-22 | | 公開日 | 2024-07-10 | | 最終更新日 | 2024-09-11 | | 実験手法 | X-RAY DIFFRACTION (3.53 Å) | | 主引用文献 | A broadly protective antibody targeting glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection.
Nat Commun, 15, 2024
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8HDL
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5GQ9
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4IDH
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4IEI
 | | Crystal Structure of the large terminase subunit gp2 of bacterial virus Sf6 complexed with ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Gene 2 protein | | 著者 | Zhao, H, Christensen, T, Kamau, Y, Tang, L. | | 登録日 | 2012-12-13 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structures of the phage Sf6 large terminase provide new insights into DNA translocation and cleavage.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4IEE
 | | Crystal Structure of the large terminase subunit gp2 of bacterial virus Sf6 complexed with ATP-r-S | | 分子名称: | Gene 2 protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | 著者 | Zhao, H, Christensen, T, Kamau, Y, Tang, L. | | 登録日 | 2012-12-13 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Structures of the phage Sf6 large terminase provide new insights into DNA translocation and cleavage.
Proc.Natl.Acad.Sci.USA, 110, 2013
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