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PDB: 1640 件

3JSG
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Crystal structure of macrophage migration inhibitory factor (mif) with hydroxyquinoline inhibitor 707 at 1.58a resolution
分子名称: 7-(pyridin-3-ylmethyl)quinolin-8-ol, Macrophage migration inhibitory factor, SULFATE ION
著者Mclean, L, Zhang, Y.
登録日2009-09-10
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Discovery of covalent inhibitors for MIF tautomerase via cocrystal structures with phantom hits from virtual screening.
Bioorg.Med.Chem.Lett., 19, 2009
4CSU
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Cryo-EM structures of the 50S ribosome subunit bound with ObgE
分子名称: 23S RRNA, 50S RIBOSOMAL PROTEIN L1, 50S RIBOSOMAL PROTEIN L11, ...
著者Feng, B, Mandava, C.S, Guo, Q, Wang, J, Cao, W, Li, N, Zhang, Y, Zhang, Y, Wang, Z, Wu, J, Sanyal, S, Lei, J, Gao, N.
登録日2014-03-10
公開日2014-06-04
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (5.5 Å)
主引用文献Structural and Functional Insights Into the Mode of Action of a Universally Conserved Obg Gtpase.
Plos Biol., 12, 2014
1C24
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E. COLI METHIONINE AMINOPEPTIDASE: METHIONINE PHOSPHINATE COMPLEX
分子名称: (1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHINIC ACID, COBALT (II) ION, METHIONINE AMINOPEPTIDASE, ...
著者Lowther, W.T, Zhang, Y, Sampson, P.B, Honek, J.F, Matthews, B.W.
登録日1999-07-22
公開日1999-11-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues.
Biochemistry, 38, 1999
1C21
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E. COLI METHIONINE AMINOPEPTIDASE: METHIONINE COMPLEX
分子名称: COBALT (II) ION, METHIONINE, METHIONINE AMINOPEPTIDASE, ...
著者Lowther, W.T, Zhang, Y, Sampson, P.B, Honek, J.F, Matthews, B.W.
登録日1999-07-22
公開日1999-11-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues.
Biochemistry, 38, 1999
1C22
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E. COLI METHIONINE AMINOPEPTIDASE: TRIFLUOROMETHIONINE COMPLEX
分子名称: 2-AMINO-4-TRIFLUOROMETHYLSULFANYL-BUTYRIC ACID, COBALT (II) ION, METHIONINE AMINOPEPTIDASE, ...
著者Lowther, W.T, Zhang, Y, Sampson, P.B, Honek, J.F, Matthews, B.W.
登録日1999-07-22
公開日1999-11-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues.
Biochemistry, 38, 1999
1C23
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E. COLI METHIONINE AMINOPEPTIDASE: METHIONINE PHOSPHONATE COMPLEX
分子名称: (1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHONIC ACID, COBALT (II) ION, METHIONINE AMINOPEPTIDASE, ...
著者Lowther, W.T, Zhang, Y, Sampson, P.B, Honek, J.F, Matthews, B.W.
登録日1999-07-22
公開日1999-11-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues.
Biochemistry, 38, 1999
1C27
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E. COLI METHIONINE AMINOPEPTIDASE:NORLEUCINE PHOSPHONATE COMPLEX
分子名称: (1-AMINO-PENTYL)-PHOSPHONIC ACID, COBALT (II) ION, METHIONINE AMINOPEPTIDASE, ...
著者Lowther, W.T, Zhang, Y, Sampson, P.B, Honek, J.F, Matthews, B.W.
登録日1999-07-22
公開日1999-11-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues.
Biochemistry, 38, 1999
4JND
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Structure of a C.elegans sex determining protein
分子名称: Ca(2+)/calmodulin-dependent protein kinase phosphatase, MAGNESIUM ION
著者Feng, Y, Zhang, Y, Ge, J, Yang, M.
登録日2013-03-15
公開日2013-06-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.652 Å)
主引用文献Structural insight into Caenorhabditis elegans sex-determining protein FEM-2.
J.Biol.Chem., 288, 2013
4K7F
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Newly identified epitope V60 from HBV core protein complexed with HLA-A*0201
分子名称: Beta-2-microglobulin, Core protein, HLA class I histocompatibility antigen, ...
著者Meng, S.D, Zhang, Y, Wu, Y, Qi, J.X.
登録日2013-04-17
公開日2013-06-05
最終更新日2022-08-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The L60V variation in hepatitis B virus core protein elicits new epitope-specific cytotoxic T lymphocytes and enhances viral replication.
J.Virol., 87, 2013
3L5S
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BU of 3l5s by Molmil
Crystal structure of macrophage migration inhibitory factor (MIF) with imidazopyrimidinylphenyl inhibitor at 1.86A resolution
分子名称: 5-ethyl-2-(phenylcarbonyl)imidazo[1,2-a]pyrimidin-7(1H)-one, Macrophage migration inhibitory factor, SULFATE ION
著者McLean, L, Zhang, Y.
登録日2009-12-22
公開日2010-03-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Fragment screening of inhibitors for MIF tautomerase reveals a cryptic surface binding site.
Bioorg.Med.Chem.Lett., 20, 2010
1NW3
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Structure of the Catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase
分子名称: ACETATE ION, S-ADENOSYLMETHIONINE, SULFATE ION, ...
著者Min, J.R, Feng, Q, Li, Z.H, Zhang, Y, Xu, R.M.
登録日2003-02-05
公開日2003-03-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the Catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase
Cell(Cambridge,Mass.), 112, 2003
1K4V
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1.53 A Crystal Structure of the Beta-Galactoside-alpha-1,3-galactosyltransferase in Complex with UDP
分子名称: GLYCEROL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ...
著者Boix, E, Swaminathan, G.J, Zhang, Y, Natesh, R, Brew, K, Acharya, K.R.
登録日2001-10-09
公開日2002-04-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Structure of UDP complex of UDP-galactose:beta-galactoside-alpha -1,3-galactosyltransferase at 1.53-A resolution reveals a conformational change in the catalytically important C terminus.
J.Biol.Chem., 276, 2001
1NOB
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BU of 1nob by Molmil
KNOB DOMAIN FROM ADENOVIRUS SEROTYPE 12
分子名称: PROTEIN (FIBER KNOB PROTEIN)
著者Bewley, M.C, Springer, K, Zhang, Y.B, Freimuth, P, Flanagan, J.M.
登録日1999-05-05
公開日1999-11-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural analysis of the mechanism of adenovirus binding to its human cellular receptor, CAR.
Science, 286, 1999
1SQ5
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BU of 1sq5 by Molmil
Crystal Structure of E. coli Pantothenate kinase
分子名称: ADENOSINE-5'-DIPHOSPHATE, PANTOTHENOIC ACID, Pantothenate kinase
著者Ivey, R.A, Zhang, Y.-M, Virga, K.G, Hevener, K, Lee, R.E, Rock, C.O, Jackowski, S, Park, H.-W.
登録日2004-03-17
公開日2004-09-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of the pantothenate kinase.ADP.pantothenate ternary complex reveals the relationship between the binding sites for substrate, allosteric regulator, and antimetabolites.
J.Biol.Chem., 279, 2004
3EPN
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BU of 3epn by Molmil
Crystal structure of Caulobacter crescentus ThiC complexed with imidazole ribonucleotide
分子名称: 1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole, Thiamine biosynthesis protein thiC
著者Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E.
登録日2008-09-29
公開日2008-10-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
Nat.Chem.Biol., 4, 2008
3EPM
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Crystal structure of Caulobacter crescentus ThiC
分子名称: 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE, SULFATE ION, Thiamine biosynthesis protein thiC, ...
著者Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E.
登録日2008-09-29
公開日2008-10-28
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.793 Å)
主引用文献Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
Nat.Chem.Biol., 4, 2008
1PFB
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BU of 1pfb by Molmil
Structural Basis for specific binding of polycomb chromodomain to histone H3 methylated at K27
分子名称: ACETIC ACID, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
著者Min, J.R, Zhang, Y, Xu, R.-M.
登録日2003-05-24
公開日2003-10-07
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27.
Genes Dev., 17, 2003
5Z1S
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Crystal Structure Analysis of the BRD4(1)
分子名称: 1,2-ETHANEDIOL, 5-bromo-2-methoxy-N-(6-methoxy-2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)benzene-1-sulfonamide, Bromodomain-containing protein 4, ...
著者Xu, Y, Zhang, Y, Xiang, Q, Song, M, Wang, C.
登録日2017-12-28
公開日2019-01-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Y08060: A Selective BET Inhibitor for Treatment of Prostate Cancer.
Acs Med.Chem.Lett., 9, 2018
5Z1R
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Crystal Structure Analysis of the BRD4
分子名称: 1,2-ETHANEDIOL, 5-bromo-N-(2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)-2-methoxybenzene-1-sulfonamide, Bromodomain-containing protein 4, ...
著者Xu, Y, Zhang, Y, Xiang, Q, Song, M, Wang, C.
登録日2017-12-28
公開日2019-01-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Y08060: A Selective BET Inhibitor for Treatment of Prostate Cancer.
Acs Med.Chem.Lett., 9, 2018
4N6E
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Crystal structure of Amycolatopsis orientalis BexX/CysO complex
分子名称: Putative thiosugar synthase, SULFATE ION, ThiS/MoaD family protein
著者Zhang, X, Zhang, Y, Kinsland, C, Sasaki, E, Sun, H.G, Lu, M.J, Liu, T, Ou, A, Li, J, Chen, Y, Liu, H, Ealick, S.E.
登録日2013-10-11
公開日2014-05-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis.
Nature, 509, 2014
3JA8
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Cryo-EM structure of the MCM2-7 double hexamer
分子名称: ADENOSINE-5'-DIPHOSPHATE, Minichromosome Maintenance 2, Minichromosome Maintenance 3, ...
著者Li, N, Zhai, Y, Zhang, Y, Li, W, Yang, M, Lei, J, Tye, B.K, Gao, N.
登録日2015-05-09
公開日2015-08-05
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of the eukaryotic MCM complex at 3.8 angstrom
Nature, 524, 2015
4Z4J
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Crystal Structure of cellobiose 2-epimerase from Caldicellulosiruptor saccharolyticus DSM 8903
分子名称: 1,2-ETHANEDIOL, Cellobiose 2-epimerase, ISOPROPYL ALCOHOL
著者Shen, Q.Y, Zhang, Y.Z.
登録日2015-04-02
公開日2016-04-13
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.542 Å)
主引用文献Crystal Structure of cellobiose 2-epimerase from Caldicellulosiruptor saccharolyticus DSM 8903
to be published
4Z4L
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Crystal Structure of cellobiose 2-epimerase from Caldicellulosiruptor saccharolyticus DSM 8903
分子名称: 1,2-ETHANEDIOL, Cellobiose 2-epimerase
著者Shen, Q.Y, Zhang, Y.Z.
登録日2015-04-02
公開日2016-04-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.671 Å)
主引用文献Crystal Structure of cellobiose 2-epimerase from Caldicellulosiruptor saccharolyticus DSM 8903
to be published
2O0O
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Crystal structure of TL1A
分子名称: MAGNESIUM ION, TNF superfamily ligand TL1A
著者Jin, T.C, Kim, S, Guo, F, Howard, A.J, Zhang, Y.Z.
登録日2006-11-27
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray crystal structure of TNF ligand family member TL1A at 2.1A.
Biochem.Biophys.Res.Commun., 364, 2007
4FBP
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CONFORMATIONAL TRANSITION OF FRUCTOSE-1,6-BISPHOSPHATASE: STRUCTURE COMPARISON BETWEEN THE AMP COMPLEX (T FORM) AND THE FRUCTOSE 6-PHOSPHATE COMPLEX (R FORM)
分子名称: ADENOSINE MONOPHOSPHATE, FRUCTOSE 1,6-BISPHOSPHATASE
著者Ke, H, Zhang, Y, Liang, J.-Y, Lipscomb, W.N.
登録日1991-02-11
公開日1992-07-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Conformational transition of fructose-1,6-bisphosphatase: structure comparison between the AMP complex (T form) and the fructose 6-phosphate complex (R form).
Biochemistry, 30, 1991

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