6Y59
| 5-HT3A receptor in Salipro (apo, C5 symmetric) | 分子名称: | 5-hydroxytryptamine receptor 3A | 著者 | Zhang, Y, Dijkman, P.M, Zou, R, Zandl-Lang, M, Sanchez, R.M, Eckhardt-Strelau, L, Koefeler, H, Vogel, H, Yuan, S, Kudryashev, M. | 登録日 | 2020-02-25 | 公開日 | 2020-12-23 | 最終更新日 | 2021-03-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Asymmetric opening of the homopentameric 5-HT 3A serotonin receptor in lipid bilayers. Nat Commun, 12, 2021
|
|
6L74
| Thermus thermophilus initial transcription complex comprising sigma A and 5'-triphosphate RNA of 2 nt | 分子名称: | DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-10-31 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6Y5A
| Serotonin-bound 5-HT3A receptor in Salipro | 分子名称: | 5-hydroxytryptamine receptor 3A, SEROTONIN | 著者 | Zhang, Y, Dijkman, P.M, Zou, R, Zandl-Lang, M, Sanchez, R.M, Eckhardt-Strelau, L, Koefeler, H, Vogel, H, Yuan, S, Kudryashev, M. | 登録日 | 2020-02-25 | 公開日 | 2020-12-23 | 最終更新日 | 2021-03-03 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Asymmetric opening of the homopentameric 5-HT 3A serotonin receptor in lipid bilayers. Nat Commun, 12, 2021
|
|
8E4V
| |
6KQE
| Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 4 nt | 分子名称: | DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-08-17 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6KQM
| Thermus thermophilus initial transcription complex comprising sigma A and 5'-triphosphate RNA of 5 nt | 分子名称: | DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-08-18 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.197 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6KQG
| Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 6 nt | 分子名称: | DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-08-17 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.783 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6KQL
| Thermus thermophilus initial transcription complex comprising sigma A and 5'-triphosphate RNA of 4 nt | 分子名称: | DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-08-18 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6KQH
| Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 7 nt | 分子名称: | DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-08-17 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6KQN
| Thermus thermophilus initial transcription complex comprising sigma A and 5'-triphosphate RNA of 6 nt | 分子名称: | DNA (5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-08-18 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.489 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6L2G
| Crystal structure of Aspergillus fumigatus mitochondrial acetyl-CoA acetyltransferase | 分子名称: | Acetyl-CoA-acetyltransferase, putative | 著者 | Zhang, Y, Wei, W, Raimi, O.G, Ferenbach, A.T, Fang, W. | 登録日 | 2019-10-03 | 公開日 | 2020-02-12 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target. Appl.Environ.Microbiol., 86, 2020
|
|
6L2C
| Crystal structure of Aspergillus fumigatus mitochondrial acetyl-CoA acetyltransferase in complex with CoA | 分子名称: | Acetyl-CoA-acetyltransferase, putative, COENZYME A | 著者 | Zhang, Y, Wei, W, Raimi, O.G, Ferenbach, A.T, Fang, W. | 登録日 | 2019-10-03 | 公開日 | 2020-02-12 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target. Appl.Environ.Microbiol., 86, 2020
|
|
6KQF
| Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 5 nt | 分子名称: | DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-08-17 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6UTU
| Crystal structure of minor pseudopilin ternary complex of XcpVWX from the Type 2 secretion system of Pseudomonas aeruginosa in the P3 space group | 分子名称: | CALCIUM ION, Type II secretion system protein I, Type II secretion system protein J, ... | 著者 | Zhang, Y, Wang, S, Jia, Z. | 登録日 | 2019-10-30 | 公開日 | 2020-09-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | In Situ Proteolysis Condition-Induced Crystallization of the XcpVWX Complex in Different Lattices. Int J Mol Sci, 21, 2020
|
|
6J1L
| Crystal Structure Analysis of the ROR gamma(C455E) | 分子名称: | 2-[4-(ethylsulfonyl)phenyl]-N-[2'-fluoro-4'-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)[1,1'-biphenyl]-4-yl]acetamide, Nuclear receptor ROR-gamma | 著者 | zhang, Y, Li, C.C, wu, X.S. | 登録日 | 2018-12-28 | 公開日 | 2019-05-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable ROR gamma Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer. J.Med.Chem., 62, 2019
|
|
6LO8
| Cryo-EM structure of the TIM22 complex from yeast | 分子名称: | Mitochondrial import inner membrane translocase subunit TIM10, Mitochondrial import inner membrane translocase subunit TIM12, Mitochondrial import inner membrane translocase subunit TIM18, ... | 著者 | Zhang, Y, Zhou, X, Wu, X, Li, L. | 登録日 | 2020-01-04 | 公開日 | 2020-09-30 | 最終更新日 | 2021-03-17 | 実験手法 | ELECTRON MICROSCOPY (3.83 Å) | 主引用文献 | Structure of the mitochondrial TIM22 complex from yeast. Cell Res., 31, 2021
|
|
5VTM
| |
8JR0
| Cryo-EM structure of Mycobacterium tuberculosis ATP synthase in complex with TBAJ-587 | 分子名称: | (1~{S},2~{S})-1-(6-bromanyl-2-methoxy-quinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2-fluoranyl-3-methoxy-phenyl)butan-2-ol, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Zhang, Y, Lai, Y, Liu, F, Rao, Z, Gong, H. | 登録日 | 2023-06-15 | 公開日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structure of Mycobacterium tuberculosis ATP synthase To Be Published
|
|
8J0T
| Cryo-EM structure of Mycobacterium tuberculosis ATP synthase in the apo-form | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | 著者 | Zhang, Y, Lai, Y, Liu, F, Rao, Z, Gong, H. | 登録日 | 2023-04-11 | 公開日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structure of Mycobacterium tuberculosis ATP synthase To Be Published
|
|
8J0S
| Cryo-EM structure of Mycobacterium tuberculosis ATP synthase in complex with bedaquiline(BDQ) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | 著者 | Zhang, Y, Lai, Y, Liu, F, Rao, Z, Gong, H. | 登録日 | 2023-04-11 | 公開日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | 主引用文献 | Structure of Mycobacterium tuberculosis ATP synthase To Be Published
|
|
8JY0
| Crystal structure of RhoBAST complexed with TMR-DN | 分子名称: | 2,4-dinitroaniline, 5-aminocarbonyl-2-[3-(dimethylamino)-6-dimethylazaniumylidene-xanthen-9-yl]benzoate, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Zhang, Y, Xiao, Y, Xu, Z, Fang, X. | 登録日 | 2023-07-02 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural mechanisms for binding and activation of a contact-quenched fluorophore by RhoBAST. Nat Commun, 15, 2024
|
|
8J58
| Cryo-EM structure of Mycobacterium tuberculosis ATP synthase Fo in the apo-form | 分子名称: | ATP synthase subunit a, ATP synthase subunit c | 著者 | Zhang, Y, Lai, Y, Liu, F, Rao, Z, Gong, H. | 登録日 | 2023-04-21 | 公開日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Structure of Mycobacterium tuberculosis ATP synthase To Be Published
|
|
8JR1
| Cryo-EM structure of Mycobacterium tuberculosis ATP synthase Fo in complex with TBAJ-587 | 分子名称: | (1~{S},2~{S})-1-(6-bromanyl-2-methoxy-quinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2-fluoranyl-3-methoxy-phenyl)butan-2-ol, ATP synthase subunit a, ATP synthase subunit c | 著者 | Zhang, Y, Lai, Y, Liu, F, Rao, Z, Gong, H. | 登録日 | 2023-06-15 | 公開日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | 主引用文献 | Structure of Mycobacterium tuberculosis ATP synthase To Be Published
|
|
8J57
| Cryo-EM structure of Mycobacterium tuberculosis ATP synthase Fo in complex with bedaquiline(BDQ) | 分子名称: | ATP synthase subunit a, ATP synthase subunit c, Bedaquiline | 著者 | Zhang, Y, Lai, Y, Liu, F, Rao, Z, Gong, H. | 登録日 | 2023-04-21 | 公開日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Structure of Mycobacterium tuberculosis ATP synthase To Be Published
|
|
5TIG
| |