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PDB: 1273 results

5ADY
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Cryo-EM structures of the 50S ribosome subunit bound with HflX
Descriptor: 23S RRNA, 50S RIBOSOMAL PROTEIN L1, 50S RIBOSOMAL PROTEIN L10, ...
Authors:Zhang, Y, Mandava, C.S, Cao, W, Li, X, Zhang, D, Li, N, Zhang, Y, Zhang, X, Qin, Y, Mi, K, Lei, J, Sanyal, S, Gao, N.
Deposit date:2015-08-25
Release date:2015-10-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Hflx is a Ribosome Splitting Factor Rescuing Stalled Ribosomes Under Stress Conditions
Nat.Struct.Mol.Biol., 22, 2015
5WMG
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BU of 5wmg by Molmil
N-terminal bromodomain of BRD4 in complex with OTX-015
Descriptor: 1,2-ETHANEDIOL, 4-{6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1S)-1-(pyridin-2-yl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl}benzoic acid, Bromodomain-containing protein 4
Authors:Zhang, Y.
Deposit date:2017-07-28
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:BRD4 Profiling Identifies Critical Chronic Lymphocytic Leukemia Oncogenic Circuits and Reveals Sensitivity to PLX51107, a Novel Structurally Distinct BET Inhibitor.
Cancer Discov, 8, 2018
5WMD
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BU of 5wmd by Molmil
N-terminal bromodomain of BRD4 in complex with OTX-015
Descriptor: 2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]-N-(4-hydroxyphenyl)acetamide, Bromodomain-containing protein 4
Authors:Zhang, Y.
Deposit date:2017-07-28
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:BRD4 Profiling Identifies Critical Chronic Lymphocytic Leukemia Oncogenic Circuits and Reveals Sensitivity to PLX51107, a Novel Structurally Distinct BET Inhibitor.
Cancer Discov, 8, 2018
6LCY
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BU of 6lcy by Molmil
Crystal structure of Synaptotagmin-7 C2B in complex with IP6
Descriptor: INOSITOL HEXAKISPHOSPHATE, Synaptotagmin-7
Authors:Zhang, Y, Zhang, X, Rao, F, Wang, C.
Deposit date:2019-11-20
Release date:2021-03-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:5-IP 7 is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis.
Nat Metab, 3, 2021
6XNZ
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BU of 6xnz by Molmil
Structure of RAG1 (R848M/E649V)-RAG2-DNA Target Capture Complex
Descriptor: 12RSS integration strand (34-mer), 12RSS non-integration strand (34-mer), 23RSS integration strand (45-mer), ...
Authors:Zhang, Y, Corbett, E, Wu, S, Schatz, D.G.
Deposit date:2020-07-05
Release date:2020-08-26
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase.
Embo J., 39, 2020
6XNY
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BU of 6xny by Molmil
Structure of RAG1 (R848M/E649V)-RAG2-DNA Strand Transfer Complex (Paired-Form)
Descriptor: 12RSS integration strand (55-mer), 12RSS signal DNA top strand (34-mer), 23RSS integration strand (66-mer), ...
Authors:Zhang, Y, Corbett, E, Wu, S, Schatz, D.G.
Deposit date:2020-07-05
Release date:2020-08-26
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase.
Embo J., 39, 2020
4G7O
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BU of 4g7o by Molmil
Crystal structure of Thermus thermophilus transcription initiation complex containing 2 nt of RNA
Descriptor: 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', 5'-R(*GP*A)-3', ...
Authors:Zhang, Y, Ebright, R.H.
Deposit date:2012-07-20
Release date:2012-10-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.993 Å)
Cite:Structural basis of transcription initiation.
Science, 338, 2012
4G7Z
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BU of 4g7z by Molmil
Crystal structure of Thermus thermophilus transcription initiation complex containing 5-BrU at template-strand position +1
Descriptor: 5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*(BRU)P*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', DNA-directed RNA polymerase subunit alpha, ...
Authors:Zhang, Y, Ebright, R.H.
Deposit date:2012-07-20
Release date:2012-10-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.815 Å)
Cite:Structural basis of transcription initiation.
Science, 338, 2012
1MEN
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BU of 1men by Molmil
complex structure of human GAR Tfase and substrate beta-GAR
Descriptor: GLYCINAMIDE RIBONUCLEOTIDE, Phosphoribosylglycinamide formyltransferase
Authors:Zhang, Y, Desharnais, J, Greasley, S.E, Beardsley, G.P, Boger, D.L, Wilson, I.A.
Deposit date:2002-08-08
Release date:2002-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Crystal structures of human GAR Tfase of low and high pH and with substrate beta-GAR
Biochemistry, 41, 2002
4GKU
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BU of 4gku by Molmil
Crystal structure of beta lactamase in PET-15B
Descriptor: Beta-lactamase TEM
Authors:Zhang, Y, Cao, C.
Deposit date:2012-08-13
Release date:2012-10-10
Method:X-RAY DIFFRACTION (1.915 Å)
Cite:Crystal structure of beta lactamase in PET-15B
To be published
6E86
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BU of 6e86 by Molmil
Solution structure of ZZZ3 ZZ domain in complex with histone H3K4ac peptide
Descriptor: H3K4ac, ZINC ION, ZZ-type zinc finger-containing protein 3
Authors:Zhang, Y, Kutateladze, T.G.
Deposit date:2018-07-27
Release date:2018-09-19
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation.
Nat Commun, 9, 2018
5VTM
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BU of 5vtm by Molmil
The crystal structure of minor pseudopilin ternary complex of XcpVWX from the Type 2 secretion system of Pseudomonas aeruginosa
Descriptor: CALCIUM ION, Type II secretion system protein I, Type II secretion system protein J, ...
Authors:Zhang, Y, Jia, Z.
Deposit date:2017-05-17
Release date:2018-05-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.041 Å)
Cite:Structure-guided disruption of the pseudopilus tip complex inhibits the Type II secretion in Pseudomonas aeruginosa.
PLoS Pathog., 14, 2018
3ZEE
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BU of 3zee by Molmil
Electron cyro-microscopy helical reconstruction of Par-3 N terminal domain
Descriptor: PARTITIONING DEFECTIVE 3 HOMOLOG
Authors:Zhang, Y, Wang, W, Chen, J, Zhang, K, Gao, F, Gong, W, Zhang, M, Sun, F, Feng, W.
Deposit date:2012-12-05
Release date:2013-10-16
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structural Insights Into the Intrinsic Self-Assembly of Par-3 N-Terminal Domain.
Structure, 21, 2013
2GHQ
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BU of 2ghq by Molmil
CTD-specific phosphatase Scp1 in complex with peptide C-terminal domain of RNA polymerase II
Descriptor: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, DNA-directed RNA polymerase II largest subunit, MAGNESIUM ION
Authors:Zhang, Y, Noel, J.P.
Deposit date:2006-03-27
Release date:2006-12-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1.
Mol.Cell, 24, 2006
2GHT
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BU of 2ght by Molmil
CTD-specific phosphatase Scp1 in complex with peptide from C-terminal domain of RNA polymerase II
Descriptor: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, DNA-directed RNA polymerase II largest subunit, MAGNESIUM ION
Authors:Zhang, Y, Noel, J.P.
Deposit date:2006-03-27
Release date:2006-12-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1.
Mol.Cell, 24, 2006
6M0W
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BU of 6m0w by Molmil
Crystal structure of Streptococcus thermophilus Cas9 in complex with the AGAA PAM
Descriptor: CRISPR-associated endonuclease Cas9 1, DNA (28-MER), DNA (5'-D(*AP*AP*AP*GP*AP*AP*GP*C)-3'), ...
Authors:Zhang, Y, Zhang, H, Xu, X, Wang, Y, Chen, W, Wang, Y, Wu, Z, Tang, N, Wang, Y, Zhao, S, Gan, J, Ji, Q.
Deposit date:2020-02-23
Release date:2020-09-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Catalytic-state structure and engineering of Streptococcus thermophilus Cas9
Nat Catal, 2020
3LBS
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BU of 3lbs by Molmil
Crystal structure of the cytoplasmic tail of (pro)renin receptor as a MBP fusion (Maltose-bound form)
Descriptor: Maltose-binding periplasmic protein, Renin receptor, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Zhang, Y, Garavito, R.M.
Deposit date:2010-01-08
Release date:2011-02-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural analysis of the intracellular domain of (pro)renin receptor fused to maltose-binding protein.
Biochem.Biophys.Res.Commun., 407, 2011
5HYN
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BU of 5hyn by Molmil
Structure of Human Polycomb Repressive Complex 2 (PRC2) with oncogenic histone H3K27M peptide
Descriptor: H3K27M, Histone-lysine N-methyltransferase EZH2, JARID2 K116me3, ...
Authors:Zhang, Y, Justin, N, Wilson, J.R, Gamblin, S.J.
Deposit date:2016-02-01
Release date:2016-05-11
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2.
Nat Commun, 7, 2016
1N6G
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BU of 1n6g by Molmil
The structure of immature Dengue-2 prM particles
Descriptor: major envelope protein E
Authors:Zhang, Y, Corver, J, Chipman, P.R, Zhang, W, Pletnev, S.V, Sedlak, D, Baker, T.S, Strauss, J.H, Kuhn, R.J, Rossmann, M.G.
Deposit date:2002-11-10
Release date:2003-06-03
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (16 Å)
Cite:Structures of Immature flavivirus particles
EMBO J., 22, 2003
1NA4
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BU of 1na4 by Molmil
The structure of immature Yellow Fever virus particle
Descriptor: major envelope protein E
Authors:Zhang, Y, Corver, J, Chipman, P.R, Lenches, E, Zhang, W, Pletnev, S.V, Sedlak, D, Baker, T.S, Strauss, J.H, Kuhn, R.J, Rossmann, M.G.
Deposit date:2002-11-26
Release date:2003-12-09
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY
Cite:Structures of immature flavivirus particles
EMBO J., 22, 2003
6XRQ
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BU of 6xrq by Molmil
Structural descriptions of ligand interactions to DNA and RNA quadruplexes folded from the non-coding region of Pseudorabies virus
Descriptor: 2,7-bis[3-(morpholin-4-yl)propyl]-4,9-bis{[3-(morpholin-4-yl)propyl]amino}benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, POTASSIUM ION, RNA (5' GP*GP*CP*UP*CP*GP*GP*CP*GP*GP*CP*GP*GP*A-3')
Authors:Zhang, Y.S, Parkinson, G.N, Wei, D.G.
Deposit date:2020-07-13
Release date:2021-07-28
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Structural descriptions of ligand interactions to RNA quadruplexes folded from the non-coding region of Pseudorabies virus.
Biochimie, 2024
2R86
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BU of 2r86 by Molmil
Crystal structure of PurP from Pyrococcus furiosus complexed with ATP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION, ...
Authors:Zhang, Y, White, R.H, Ealick, S.E.
Deposit date:2007-09-10
Release date:2007-12-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii.
Biochemistry, 47, 2008
2R7K
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BU of 2r7k by Molmil
Crystal structure of FAICAR synthetase (PurP) from M. jannaschii complexed with AMPPCP and AICAR
Descriptor: 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, CHLORIDE ION, ...
Authors:Zhang, Y, White, R.H, Ealick, S.E.
Deposit date:2007-09-09
Release date:2007-12-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii.
Biochemistry, 47, 2008
2R7M
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BU of 2r7m by Molmil
Crystal structure of FAICAR synthetase (PurP) from M. jannaschii complexed with AMP
Descriptor: 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ...
Authors:Zhang, Y, White, R.H, Ealick, S.E.
Deposit date:2007-09-09
Release date:2007-12-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii.
Biochemistry, 47, 2008
2R84
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BU of 2r84 by Molmil
Crystal structure of PurP from Pyrococcus furiosus complexed with AMP and AICAR
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE MONOPHOSPHATE, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, ...
Authors:Zhang, Y, White, R.H, Ealick, S.E.
Deposit date:2007-09-10
Release date:2007-12-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii.
Biochemistry, 47, 2008

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数据于2024-07-17公开中

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