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PDB: 1282 件
9C11
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Crystal structure of Staphylococcal nuclease variant Delta+PHS L36R at cryogenic temperature
分子名称: CALCIUM ION, Nuclease A, THYMIDINE-3',5'-DIPHOSPHATE
著者Zhang, Y, Schlessman, J.L, Siegler, M.A, Garcia-Moreno E, B.
登録日2024-05-28
公開日2024-06-19
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Domain-swapping promoted by the introduction of a charge in the hydrophobic interior of a protein
To Be Published
6GFM
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BU of 6gfm by Molmil
Crystal structure of the Escherichia coli nucleosidase PpnN (pppGpp-form)
分子名称: Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase, guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate)
著者Zhang, Y, Baerentsen, R.L, Gerdes, K, Brodersen, D.E.
登録日2018-05-01
公開日2019-04-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献(p)ppGpp Regulates a Bacterial Nucleosidase by an Allosteric Two-Domain Switch.
Mol.Cell, 74, 2019
6O3Y
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BU of 6o3y by Molmil
Crystal structure of yeast Nrd1 CID in complex with Sen1 NIM3
分子名称: CHLORIDE ION, Helicase SEN1, Protein NRD1
著者Zhang, Y, Tong, L.
登録日2019-02-27
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.799 Å)
主引用文献Identification of Three Sequence Motifs in the Transcription Termination Factor Sen1 that Mediate Direct Interactions with Nrd1.
Structure, 27, 2019
6O3W
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Crystal structure of yeast Nrd1 CID in complex with Sen1 NIM1
分子名称: Helicase SEN1, Protein NRD1
著者Zhang, Y, Tong, L.
登録日2019-02-27
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification of Three Sequence Motifs in the Transcription Termination Factor Sen1 that Mediate Direct Interactions with Nrd1.
Structure, 27, 2019
6GFL
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Crystal structure of the Escherichia coli nucleosidase PpnN (apo form)
分子名称: Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase
著者Zhang, Y, Baerentsen, R.L, Gerdes, K, Brodersen, D.E.
登録日2018-05-01
公開日2019-04-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献(p)ppGpp Regulates a Bacterial Nucleosidase by an Allosteric Two-Domain Switch.
Mol.Cell, 74, 2019
6B40
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BbRAGL-3'TIR synaptic complex with nicked DNA refined with C2 symmetry
分子名称: 31TIR intact strand, 31TIR pre-nicked strand of flanking DNA, 31TIR pre-nicked strand of signal DNA, ...
著者Zhang, Y, Cheng, T.C, Xiong, Y, Schatz, D.G.
登録日2017-09-25
公開日2019-03-20
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Transposon molecular domestication and the evolution of the RAG recombinase.
Nature, 569, 2019
6O3X
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BU of 6o3x by Molmil
Crystal structure of yeast Nrd1 CID in complex with Sen1 NIM2
分子名称: CHLORIDE ION, Helicase SEN1, Protein NRD1
著者Zhang, Y, Tong, L.
登録日2019-02-27
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.994 Å)
主引用文献Identification of Three Sequence Motifs in the Transcription Termination Factor Sen1 that Mediate Direct Interactions with Nrd1.
Structure, 27, 2019
7VWP
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BU of 7vwp by Molmil
Structure of the flavin-dependent monooxygenase FlsO1 from the biosynthesis of fluostatinsin
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, FlsO1, PHOSPHATE ION, ...
著者Zhang, Y, Yang, C, Zhang, L, Zhang, C.
登録日2021-11-11
公開日2022-09-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Biochemical and structural insights of multifunctional flavin-dependent monooxygenase FlsO1-catalyzed unexpected xanthone formation
Nat Commun, 13, 2022
7Q83
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Crystal structure of S. cerevisiae Sso2 in complex with the pleckstrin homology domain of Sec3
分子名称: Exocyst complex component SEC3, Protein SSO2
著者Zhang, Y, Dong, G.
登録日2021-11-09
公開日2022-08-31
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Double NPY motifs at the N-terminus of the yeast t-SNARE Sso2 synergistically bind Sec3 to promote membrane fusion.
Elife, 11, 2022
1Z36
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Crystal structure of Trichomonas vaginalis purine nucleoside phosphorylase complexed with formycin A
分子名称: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, purine nucleoside phosphorylase
著者Zhang, Y, Wang, W.H, Wu, S.W, Wang, C.C, Ealick, S.E.
登録日2005-03-10
公開日2005-03-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.
J.Biol.Chem., 280, 2005
1Z35
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Crystal structure of Trichomonas vaginalis purine nucleoside phosphorylase complexed with 2-fluoroadenosine
分子名称: 2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, purine nucleoside phosphorylase
著者Zhang, Y, Wang, W.H, Wu, S.W, Wang, C.C, Ealick, S.E.
登録日2005-03-10
公開日2005-03-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.
J.Biol.Chem., 280, 2005
5DX4
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BU of 5dx4 by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with benzo[cd]indol-2(1H)-one ligand
分子名称: 1,2-ETHANEDIOL, 5-bromo-N-(1-ethyl-2-oxo-1,2-dihydrobenzo[cd]indol-6-yl)-2-methoxybenzenesulfonamide, Bromodomain-containing protein 4, ...
著者Zhang, Y, Song, M, Liu, Z, Xue, X, Xu, Y.
登録日2015-09-23
公開日2016-01-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of Benzo[cd]indol-2(1H)-ones as Potent and Specific BET Bromodomain Inhibitors: Structure-Based Virtual Screening, Optimization, and Biological Evaluation
J.Med.Chem., 59, 2016
1Z34
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BU of 1z34 by Molmil
Crystal structure of Trichomonas vaginalis purine nucleoside phosphorylase complexed with 2-fluoro-2'-deoxyadenosine
分子名称: 5-(6-AMINO-2-FLUORO-PURIN-9-YL)-2-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-OL, purine nucleoside phosphorylase
著者Zhang, Y, Wang, W.H, Wu, S.W, Wang, C.C, Ealick, S.E.
登録日2005-03-10
公開日2005-03-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.
J.Biol.Chem., 280, 2005
1Z33
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Crystal structure of Trichomonas vaginalis purine nucleoside phosphorylase
分子名称: purine nucleoside phosphorylase
著者Zhang, Y, Wang, W.H, Wu, S.W, Wang, C.C, Ealick, S.E.
登録日2005-03-10
公開日2005-03-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.
J.Biol.Chem., 280, 2005
1Z39
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Crystal structure of Trichomonas vaginalis purine nucleoside phosphorylase complexed with 2'-deoxyinosine
分子名称: 2'-DEOXYINOSINE, purine nucleoside phosphorylase
著者Zhang, Y, Wang, W.H, Wu, S.W, Wang, C.C, Ealick, S.E.
登録日2005-03-10
公開日2005-03-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.
J.Biol.Chem., 280, 2005
1Z38
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Crystal structure of Trichomonas vaginalis purine nucleoside phosphorylase complexed with inosine
分子名称: INOSINE, purine nucleoside phosphorylase
著者Zhang, Y, Wang, W.H, Wu, S.W, Wang, C.C, Ealick, S.E.
登録日2005-03-10
公開日2005-03-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.
J.Biol.Chem., 280, 2005
1Z37
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Crystal structure of Trichomonas vaginalis purine nucleoside phosphorylase complexed with adenosine
分子名称: ADENOSINE, purine nucleoside phosphorylase
著者Zhang, Y, Wang, W.H, Wu, S.W, Wang, C.C, Ealick, S.E.
登録日2005-03-10
公開日2005-03-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.
J.Biol.Chem., 280, 2005
6A37
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X-ray structure of cyclohexanone monooxygenase from Acinetobacter calcoaceticus
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Putative flavin-binding monooxygenase
著者Zhang, Y, Yu, H.L, Xu, J.H.
登録日2018-06-15
公開日2019-03-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Engineering of Cyclohexanone Monooxygenase for the Enantioselective Synthesis of (S)-Omeprazole
Acs Sustain Chem Eng
6P79
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BU of 6p79 by Molmil
Engineered single chain antibody C9+C14 ScFv
分子名称: Engineered antibody heavy chain, Engineered antibody light chain
著者Zhang, Y, Li, W, Marshall, N.
登録日2019-06-05
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.583 Å)
主引用文献Computer-based Engineering of Thermostabilized Antibody Fragments.
Aiche J, 66, 2020
6C00
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BU of 6c00 by Molmil
Solution structure of translation initiation factor 1 from Clostridium difficile
分子名称: Translation initiation factor IF-1
著者Zhang, Y, Aguilar, F.
登録日2017-12-26
公開日2019-01-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献1H,13C and15N resonance assignments and structure prediction of translation initiation factor 1 from Clostridium difficile.
Biomol.Nmr Assign., 13, 2019
6JJI
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BU of 6jji by Molmil
Crystal structure of a two-quartet RNA parallel G-quadruplex complexed with the porphyrin TMPyP4 (1:1)
分子名称: (1Z,4Z,9Z,15Z)-5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,23-dihydroporphyrin, POTASSIUM ION, RNA (5'-R(*GP*GP*CP*UP*CP*GP*GP*CP*GP*GP*CP*GP*GP*A)-3')
著者Zhang, Y.S, Parkinson, G.N, Wei, D.G.
登録日2019-02-25
公開日2020-02-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths.
Nucleic Acids Res., 48, 2020
6JJH
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Crystal structure of a two-quartet RNA parallel G-quadruplex complexed with the porphyrin TMPyP4
分子名称: (1Z,4Z,9Z,15Z)-5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,23-dihydroporphyrin, POTASSIUM ION, RNA (5'-R(*GP*GP*CP*UP*CP*GP*GP*CP*GP*GP*CP*GP*GP*A)-3')
著者Zhang, Y.S, EI Omari, K, Duman, R, Wagner, A, Parkinson, G.N, Wei, D.G.
登録日2019-02-25
公開日2020-02-26
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths.
Nucleic Acids Res., 48, 2020
6JJF
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Crystal structure of a two-quartet DNA mixed-parallel/antiparallel G-quadruplex
分子名称: COBALT HEXAMMINE(III), DNA (5'-D(*GP*GP*CP*TP*CP*GP*GP*CP*GP*GP*CP*GP*GP*A)-3'), POTASSIUM ION, ...
著者Zhang, Y.S, EI Omari, K, Duman, R, Wagner, A, Parkinson, G.N, Wei, D.G.
登録日2019-02-25
公開日2020-02-26
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths.
Nucleic Acids Res., 48, 2020
8CZJ
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BU of 8czj by Molmil
A bacteria Zrt/Irt-like protein in the apo state
分子名称: Putative membrane protein, SULFATE ION, [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate
著者Zhang, Y, Hu, J.
登録日2022-05-24
公開日2023-02-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.751 Å)
主引用文献Structural insights into the elevator-type transport mechanism of a bacterial ZIP metal transporter.
Nat Commun, 14, 2023
8E4V
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Solution structure of the WH domain of MORF
分子名称: Isoform 3 of Histone acetyltransferase KAT6B
著者Zhang, Y, Kutateladze, T.G.
登録日2022-08-19
公開日2023-05-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain.
Nat Commun, 14, 2023

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