8XKN
| Cryo-EM structure of tail tube protein | Descriptor: | a protein | Authors: | Zhang, H, Li, Z, Li, X.Z. | Deposit date: | 2023-12-23 | Release date: | 2024-05-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Insights into the modulation of bacterial NADase activity by phage proteins. Nat Commun, 15, 2024
|
|
7YRI
| |
7YRJ
| |
8I88
| Cryo-EM structure of TIR-APAZ/Ago-gRNA complex | Descriptor: | Piwi domain-containing protein, RNA (5'-R(P*GP*A)-3'), TIR domain-containing protein | Authors: | Zhang, H, Li, Z, Yu, G.M, Li, X.Z, Wang, X.S. | Deposit date: | 2023-02-03 | Release date: | 2023-07-05 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural insights into mechanisms of Argonaute protein-associated NADase activation in bacterial immunity. Cell Res., 33, 2023
|
|
8IN8
| Cryo-EM structure of the target ssDNA-bound SIR2-APAZ/Ago-gRNA quaternary complex | Descriptor: | DNA (5'-D(P*AP*AP*CP*GP*AP*CP*GP*TP*CP*TP*AP*AP*GP*AP*AP*AP*CP*CP*AP*TP*TP*AP*A)-3'), MAGNESIUM ION, Piwi domain protein, ... | Authors: | Zhang, H, Li, Z, Yu, G.M, Li, X.Z, Wang, X.S. | Deposit date: | 2023-03-08 | Release date: | 2023-07-05 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into mechanisms of Argonaute protein-associated NADase activation in bacterial immunity. Cell Res., 33, 2023
|
|
5XOO
| The structure of hydra Fam20 with sugar | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE, Glycosaminoglycan xylosylkinase, ... | Authors: | Zhang, H, Xiao, J. | Deposit date: | 2017-05-29 | Release date: | 2018-04-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structure and evolution of the Fam20 kinases Nat Commun, 9, 2018
|
|
8HYJ
| |
8WKN
| Cryo-EM structure of DSR2-DSAD1 | Descriptor: | SIR2-like domain-containing protein, SPbeta prophage-derived uncharacterized protein YotI | Authors: | Zhang, H, Li, Z, Li, X.Z. | Deposit date: | 2023-09-28 | Release date: | 2024-05-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Insights into the modulation of bacterial NADase activity by phage proteins. Nat Commun, 15, 2024
|
|
8W56
| Cryo-EM structure of DSR2-DSAD1 state 1 | Descriptor: | SIR2-like domain-containing protein, SPbeta prophage-derived uncharacterized protein YotI | Authors: | Zhang, H, Li, Z, Li, X.Z. | Deposit date: | 2023-08-25 | Release date: | 2024-05-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.59 Å) | Cite: | Insights into the modulation of bacterial NADase activity by phage proteins. Nat Commun, 15, 2024
|
|
4X2A
| Crystal structure of mouse glyoxalase I complexed with baicalein | Descriptor: | 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one, Lactoylglutathione lyase, ZINC ION | Authors: | Zhang, H, Zhai, J, Zhang, L, Li, C, Zhao, Y, Hu, X. | Deposit date: | 2014-11-26 | Release date: | 2015-09-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | In Vitro Inhibition of Glyoxalase І by Flavonoids: New Insights from Crystallographic Analysis. Curr Top Med Chem, 16, 2016
|
|
5XB0
| |
6XP5
| Head-Middle module of Mediator | Descriptor: | HEAT, Med22, Mediator of RNA polymerase II transcription subunit 1, ... | Authors: | Zhang, H.Q, Chen, D.C, Kornberg, R.D. | Deposit date: | 2020-07-08 | Release date: | 2021-03-03 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Mediator structure and conformation change. Mol.Cell, 81, 2021
|
|
8WFN
| Cryo-EM structure of DSR2-TTP | Descriptor: | SIR2-like domain-containing protein, tail tube protein(TTP) | Authors: | Zhang, H, Li, Z, Li, X.Z. | Deposit date: | 2023-09-19 | Release date: | 2024-05-01 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (4.48 Å) | Cite: | Cryo-EM structure of DSR2-TTP To Be Published
|
|
4RTA
| |
6LJ8
| Crystal structure of NDM-1 in complex with D-captopril derivative wss04134 | Descriptor: | 1,2-ETHANEDIOL, 2-[1-[(2S)-2-methyl-3-sulfanyl-propanoyl]piperidin-4-yl]ethanoic acid, Metallo-beta-lactamase type 2, ... | Authors: | Zhang, H, Ma, G. | Deposit date: | 2019-12-13 | Release date: | 2020-12-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure-guided optimization of D-captopril for discovery of potent NDM-1 inhibitors. Bioorg.Med.Chem., 29, 2020
|
|
1GP7
| |
6LJ2
| Crystal structure of NDM-1 in complex with heterodimer of D-captopril derivative wss02127 stereoisomer | Descriptor: | (1R)-2-[(2S)-2-methyl-3-sulfanyl-propanoyl]-3,4-dihydro-1H-isoquinoline-1-carboxylic acid, (1S)-2-[(2S)-2-methyl-3-sulfanyl-propanoyl]-3,4-dihydro-1H-isoquinoline-1-carboxylic acid, HYDROXIDE ION, ... | Authors: | Zhang, H, Ma, G. | Deposit date: | 2019-12-13 | Release date: | 2020-12-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structure-guided optimization of D-captopril for discovery of potent NDM-1 inhibitors. Bioorg.Med.Chem., 29, 2020
|
|
8HS8
| |
1HS1
| |
1HS3
| |
1HS4
| |
6LJ1
| |
6LJ0
| Crystal structure of NDM-1 in complex with D-captopril derivative wss02122 | Descriptor: | (2R)-1-[(2S)-2-methyl-3-sulfanyl-propanoyl]piperidine-2-carboxylic acid, Metallo-beta-lactamase type 2, ZINC ION | Authors: | Zhang, H, Ma, G. | Deposit date: | 2019-12-13 | Release date: | 2020-12-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structure-guided optimization of D-captopril for discovery of potent NDM-1 inhibitors. Bioorg.Med.Chem., 29, 2020
|
|
6LJ5
| Crystal structure of NDM-1 in complex with D-captopril derivative wss04145 | Descriptor: | 1,2-ETHANEDIOL, 1-[(2S)-2-methyl-3-sulfanyl-propanoyl]piperidine-4-carboxylic acid, Metallo-beta-lactamase type 2, ... | Authors: | Zhang, H, Ma, G. | Deposit date: | 2019-12-13 | Release date: | 2020-12-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.26 Å) | Cite: | Structure-guided optimization of D-captopril for discovery of potent NDM-1 inhibitors. Bioorg.Med.Chem., 29, 2020
|
|
6LJ6
| |