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PDB: 1650 件

5ZX2
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Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ECF sigma factor sigma H and 7nt RNA
分子名称: DNA (47-MER), DNA (48-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Li, L, Zhang, Y.
登録日2018-05-17
公開日2019-03-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for transcription initiation by bacterial ECF sigma factors.
Nat Commun, 10, 2019
7CQQ
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GmaS in complex with AMPPNP and MetSox
分子名称: (2S)-2-AMINO-4-(METHYLSULFONIMIDOYL)BUTANOIC ACID, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Li, C.Y, Zhang, Y.Z.
登録日2020-08-11
公開日2020-11-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.295 Å)
主引用文献Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine.
J.Biol.Chem., 296, 2020
3VFE
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Virtual Screening and X-Ray Crystallography for Human Kallikrein 6 Inhibitors with an Amidinothiophene P1 Group
分子名称: 4-{[(3R)-3-{[(7-methoxynaphthalen-2-yl)sulfonyl](thiophen-3-ylmethyl)amino}-2-oxopyrrolidin-1-yl]methyl}thiophene-2-carboximidamide, Kallikrein-6
著者Chen, X, Zhang, Y, Xia, T, Wang, R.
登録日2012-01-09
公開日2012-11-21
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Virtual Screening and X-ray Crystallography for Human Kallikrein 6 Inhibitors with an Amidinothiophene P1 Group.
Acs Med.Chem.Lett., 3, 2012
3EPM
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BU of 3epm by Molmil
Crystal structure of Caulobacter crescentus ThiC
分子名称: 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE, SULFATE ION, Thiamine biosynthesis protein thiC, ...
著者Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E.
登録日2008-09-29
公開日2008-10-28
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.793 Å)
主引用文献Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
Nat.Chem.Biol., 4, 2008
7CQL
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Apo GmaS without ligand
分子名称: Type III glutamate--ammonia ligase
著者Li, C.Y, Zhang, Y.Z.
登録日2020-08-11
公開日2020-11-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine.
J.Biol.Chem., 296, 2020
7CQN
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GmaS in complex with AMPPCP
分子名称: PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Type III glutamate--ammonia ligase
著者Li, C.Y, Zhang, Y.Z.
登録日2020-08-11
公開日2020-11-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.962 Å)
主引用文献Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine.
J.Biol.Chem., 296, 2020
7C8J
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Structural basis for cross-species recognition of COVID-19 virus spike receptor binding domain to bat ACE2
分子名称: Angiotensin-converting enzyme, SARS-CoV-2 Receptor binding domain, ZINC ION
著者Liu, K.F, Wang, J, Tan, S.G, Niu, S, Wu, L.L, Zhang, Y.F, Pan, X.Q, Meng, Y.M, Chen, Q, Wang, Q.H, Wang, H.W, Qi, J.X, Gao, G.F.
登録日2020-06-01
公開日2021-01-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Cross-species recognition of SARS-CoV-2 to bat ACE2.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CQU
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GmaS/ADP/MetSox-P complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, MAGNESIUM ION, ...
著者Li, C.Y, Zhang, Y.Z.
登録日2020-08-11
公開日2020-11-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine.
J.Biol.Chem., 296, 2020
8H7G
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Cryo-EM structure of the human SAGA complex
分子名称: Ataxin-7, STAGA complex 65 subunit gamma, Splicing factor 3B subunit 3, ...
著者Huang, J, Zhang, Y.
登録日2022-10-20
公開日2022-12-14
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structure of human SAGA transcriptional coactivator complex.
Cell Discov, 8, 2022
2K29
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Structure of the DBD domain of E. coli antitoxin RelB
分子名称: Antitoxin RelB
著者Li, G, Zhang, Y, Inouye, M, Ikura, M.
登録日2008-03-28
公開日2008-04-22
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structural mechanism of transcriptional autorepression of the Escherichia coli RelB/RelE antitoxin/toxin module.
J.Mol.Biol., 380, 2008
2M19
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Solution structure of the Haloferax volcanii HVO 2177 protein
分子名称: Molybdopterin converting factor subunit 1
著者Li, Y, Maciejewski, M.W, Martin, J, Jin, K, Zhang, Y, Lu, M, Maupin-Furlow, J.A, Hao, B.
登録日2012-11-21
公開日2013-08-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Crystal structure of the ubiquitin-like small archaeal modifier protein 2 from Haloferax volcanii.
Protein Sci., 22, 2013
5BTY
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Structure of the middle domain of lpg1496 from Legionella pneumophila in P21 space group
分子名称: lpg1496
著者Kozlov, G, Zhang, Y, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2015-06-03
公開日2015-08-26
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structure of the Legionella Effector, lpg1496, Suggests a Role in Nucleotide Metabolism.
J.Biol.Chem., 290, 2015
1F46
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THE BACTERIAL CELL-DIVISION PROTEIN ZIPA AND ITS INTERACTION WITH AN FTSZ FRAGMENT REVEALED BY X-RAY CRYSTALLOGRAPHY
分子名称: CELL DIVISION PROTEIN ZIPA
著者Mosyak, L, Zhang, Y, Glasfeld, E, Stahl, M, Somers, W.S.
登録日2000-06-07
公開日2001-06-13
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The bacterial cell-division protein ZipA and its interaction with an FtsZ fragment revealed by X-ray crystallography.
EMBO J., 19, 2000
6LK6
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BU of 6lk6 by Molmil
MLKL mutant - T357AS358A
分子名称: Mixed lineage kinase domain-like protein
著者Wang, H, Li, S, Zhang, Y.
登録日2019-12-18
公開日2020-12-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献The MLKL kinase-like domain dimerization is an indispensable step of mammalian MLKL activation in necroptosis signaling.
Cell Death Dis, 12, 2021
8H7Q
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Cryo-EM structure of Synechocystis sp. PCC6714 Cascade at 3.8 angstrom resolution
分子名称: CRISPR RNA, CRISPR associated protein Cas11b, CRISPR associated protein Cas5, ...
著者Xiao, Y, Lu, M, Yu, C, Zhang, Y.
登録日2022-10-20
公開日2023-10-25
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structure of Synechocystis sp. PCC6714 Cascade at 3.8 angstrom resolution
To Be Published
7E6R
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Crystal structure of HCoV-NL63 3C-like protease,pH5.6
分子名称: 3C-like proteinase
著者Gao, H.X, Zhang, Y.T, Zhong, F.L, Zhou, X.L, Li, J, Zhang, J.
登録日2021-02-23
公開日2021-10-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of human coronavirus NL63 main protease at different pH values
Acta Crystallogr.,Sect.F, 77, 2021
7E6L
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Crystal structure of HCoV-NL63 3C-like protease,pH5.0
分子名称: 3C-like proteinase
著者Gao, H.X, Zhang, Y.T, Zhou, X.L, Zhong, F.L, Li, J, Zhang, J.
登録日2021-02-22
公開日2021-10-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.78037143 Å)
主引用文献Crystal structures of human coronavirus NL63 main protease at different pH values
Acta Crystallogr.,Sect.F, 77, 2021
7E6M
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Crystal structure of Human coronavirus NL63 3C-like protease
分子名称: 3C-like proteinase
著者Gao, H.X, Zhang, Y.T, Zhong, F.L, Zhou, X.L, Li, J, Zhang, J.
登録日2021-02-22
公開日2021-10-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.83445024 Å)
主引用文献Crystal structures of human coronavirus NL63 main protease at different pH values
Acta Crystallogr.,Sect.F, 77, 2021
7E6N
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BU of 7e6n by Molmil
Crystal structure of HCoV-NL63 3C-like protease,pH5.2
分子名称: 3C-like proteinase
著者Gao, H.X, Zhang, Y.T, Zhou, X.L, Zhong, F.L, Li, J, Zhang, J.
登録日2021-02-22
公開日2021-10-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8413 Å)
主引用文献Crystal structures of human coronavirus NL63 main protease at different pH values
Acta Crystallogr.,Sect.F, 77, 2021
3NR9
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BU of 3nr9 by Molmil
Structure of human CDC2-like kinase 2 (CLK2)
分子名称: (5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-one, Dual specificity protein kinase CLK2
著者Chaikuad, A, Savitsky, P, Krojer, T, Muniz, J.R.C, Filippakopoulos, P, Rellos, P, Keates, T, Fedorov, O, Pike, A.C.W, Eswaran, J, Berridge, G, Phillips, C, Zhang, Y, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
登録日2010-06-30
公開日2010-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Structure of human CDC2-like kinase 2 (CLK2)
To be Published
8H67
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type I-B Cascade bound to a PAM-containing dsDNA target at 3.8 angstrom resolution.
分子名称: CRISPR RNA, CRISPR associated protein Cas11b, CRISPR associated protein Cas5, ...
著者Xiao, Y, Lu, M, Yu, C, Zhang, Y.
登録日2022-10-15
公開日2024-05-01
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure and genome editing of type I-B CRISPR-Cas.
Nat Commun, 15, 2024
7DHI
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Cryo-EM structure of the partial agonist salbutamol-bound beta2 adrenergic receptor-Gs protein complex.
分子名称: Beta-2 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Yang, F, Ling, S.L, Zhou, Y.X, Zhang, Y.N, Lv, P, Liu, S.L, Fang, W, Sun, W.J, Hu, L.Y.A.
登録日2020-11-15
公開日2020-12-16
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Different Conformational Responses of the beta2-Adrenergic Receptor-Gs Complex upon Binding of the Partial Agonist Salbutamol or the Full Agonist Isoprenaline
Natl Sci Rev, 2020
3SOB
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BU of 3sob by Molmil
The structure of the first YWTD beta propeller domain of LRP6 in complex with a FAB
分子名称: CALCIUM ION, Low-density lipoprotein receptor-related protein 6, antibody heavy chain, ...
著者Wang, W, Bourhis, E, Tam, C, Zhang, Y, Rouge, L, Wu, Y, Franke, Y, Cochran, A.G.
登録日2011-06-30
公開日2011-09-21
最終更新日2014-05-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Wnt antagonists bind through a short peptide to the first beta-propeller domain of LRP5/6.
Structure, 19, 2011
6JBQ
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CryoEM structure of Escherichia coli sigmaE transcription initiation complex containing 5nt of RNA
分子名称: DNA (48-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Fang, C.L, Zhang, Y.
登録日2019-01-26
公開日2019-05-29
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Structures and mechanism of transcription initiation by bacterial ECF factors.
Nucleic Acids Res., 47, 2019
7EJB
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Crystal structure of juvenile hormone acid methyltransferase JHAMT mutant Q15E
分子名称: Juvenile hormone acid methyltransferase
著者Guo, P.C, Zhang, Y.S, Zhang, l, Xu, H.Y, Xia, Q.Y.
登録日2021-04-01
公開日2022-04-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural insights into catalytic mechanism of juvenile hormone acid methyltransferase JHAMT
To Be Published

222415

件を2024-07-10に公開中

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