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PDB: 1659 件
2O3J
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BU of 2o3j by Molmil
Structure of Caenorhabditis Elegans UDP-Glucose Dehydrogenase
分子名称: GLYCEROL, UDP-glucose 6-dehydrogenase
著者Zhang, Y, Zhan, C, Patskovsky, Y, Ramagopal, U, Shi, W, Toro, R, Wengerter, B.C, Milst, S, Vidal, M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-12-01
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Crystal Structure of Caenorhabditis Elegans Udp-Glucose Dehydrogenase
To be Published
7W3Z
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BU of 7w3z by Molmil
Cryo-EM Structure of Human Gastrin Releasing Peptide Receptor in complex with the agonist Gastrin Releasing Peptide and Gq heterotrimers
分子名称: Gastrin Releasing Peptide PRGNHWAVGHLM(NH2), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhan, Y, Peng, S, Zhang, H.
登録日2021-11-26
公開日2023-02-22
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structures of human gastrin-releasing peptide receptors bound to antagonist and agonist for cancer and itch therapy.
Proc.Natl.Acad.Sci.USA, 120, 2023
7W40
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BU of 7w40 by Molmil
Cryo-EM Structure of Human Gastrin Releasing Peptide Receptor in complex with the agonist Bombesin (6-14) [D-Phe6, beta-Ala11, Phe13, Nle14] and Gq heterotrimers
分子名称: Bombesin, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhan, Y, Peng, S, Zhang, H.
登録日2021-11-26
公開日2023-02-22
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structures of human gastrin-releasing peptide receptors bound to antagonist and agonist for cancer and itch therapy.
Proc.Natl.Acad.Sci.USA, 120, 2023
8S54
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BU of 8s54 by Molmil
RNA polymerase II early elongation complex bound to TFIIE and TFIIF - state b (composite structure)
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ...
著者Zhan, Y, Grabber, F, Oberbeckmann, E, Dienemann, C, Cramer, P.
登録日2024-02-22
公開日2024-04-17
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Three-step mechanism of promoter escape by RNA polymerase II.
Mol.Cell, 84, 2024
8S5N
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BU of 8s5n by Molmil
RNA polymerase II core initially transcribing complex with an ordered RNA of 12 nt
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ...
著者Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P.
登録日2024-02-24
公開日2024-04-10
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Three-step mechanism of promoter escape by RNA polymerase II.
Mol.Cell, 84, 2024
8S55
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BU of 8s55 by Molmil
RNA polymerase II early elongation complex bound to TFIIE and TFIIF - state a (composite structure)
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ...
著者Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P.
登録日2024-02-22
公開日2024-04-17
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Three-step mechanism of promoter escape by RNA polymerase II.
Mol.Cell, 84, 2024
8S51
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BU of 8s51 by Molmil
RNA polymerase II core initially transcribing complex with an ordered RNA of 8 nt
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ...
著者Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P.
登録日2024-02-22
公開日2024-04-17
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Three-step mechanism of promoter escape by RNA polymerase II.
Mol.Cell, 84, 2024
8S52
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BU of 8s52 by Molmil
RNA polymerase II core initially transcribing complex with an ordered RNA of 10 nt
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ...
著者Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P.
登録日2024-02-22
公開日2024-04-17
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Three-step mechanism of promoter escape by RNA polymerase II.
Mol.Cell, 84, 2024
3ZEE
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BU of 3zee by Molmil
Electron cyro-microscopy helical reconstruction of Par-3 N terminal domain
分子名称: PARTITIONING DEFECTIVE 3 HOMOLOG
著者Zhang, Y, Wang, W, Chen, J, Zhang, K, Gao, F, Gong, W, Zhang, M, Sun, F, Feng, W.
登録日2012-12-05
公開日2013-10-16
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Structural Insights Into the Intrinsic Self-Assembly of Par-3 N-Terminal Domain.
Structure, 21, 2013
5CRZ
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BU of 5crz by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with benzo[cd]indol-2(1H)-one ligand
分子名称: 1,2-ETHANEDIOL, 2-chloro-N-(1-ethyl-2-oxo-1,2-dihydrobenzo[cd]indol-6-yl)-4-fluorobenzenesulfonamide, Bromodomain-containing protein 4, ...
著者Zhang, Y, Song, M, Liu, Z, Xue, X, Xu, Y.
登録日2015-07-23
公開日2016-01-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Discovery of Benzo[cd]indol-2(1H)-ones as Potent and Specific BET Bromodomain Inhibitors: Structure-Based Virtual Screening, Optimization, and Biological Evaluation
J.Med.Chem., 59, 2016
8YM1
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BU of 8ym1 by Molmil
Structure of SADS-CoV Virus Nucleocapsid Protein
分子名称: nucleocapsid phosphoprotein
著者Zhang, Y, Wu, F, Xu, W.
登録日2024-03-08
公開日2024-07-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Unraveling the assembly mechanism of SADS-CoV virus nucleocapsid protein: insights from RNA binding, dimerization, and epitope diversity profiling
J.Virol., 2024
6Q1F
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BU of 6q1f by Molmil
Atomic structure of the Human Herpesvirus 6B Capsid and Capsid-Associated Tegument Complexes
分子名称: Large structural phosphoprotein, Major capsid protein, Small capsomere-interacting protein, ...
著者Zhang, Y.B, Liu, W, Li, Z.H, Kumar, V, Alvarez-Cabrera, A.L, Leibovitch, E, Cui, Y.X, Mei, Y, Bi, G.Q, Jacobson, S, Zhou, Z.H.
登録日2019-08-03
公開日2019-12-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Atomic structure of the human herpesvirus 6B capsid and capsid-associated tegument complexes.
Nat Commun, 10, 2019
8JI9
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BU of 8ji9 by Molmil
Crystal Structure of cas7 and AcrIE10 complex
分子名称: Uncharacterized protein, type I-E Cascade subunit cas7
著者Zhang, Y, Yu, C.Z, Sun, S.Y.
登録日2023-05-26
公開日2024-07-24
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献A new anti-CRISPR gene promotes the spread of drug-resistance plasmids in Klebsiella pneumoniae.
Nucleic Acids Res., 2024
7BZ2
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BU of 7bz2 by Molmil
Cryo-EM structure of the formoterol-bound beta2 adrenergic receptor-Gs protein complex.
分子名称: Beta2 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhang, Y.N, Yang, F, Ling, S.L, Lv, P, Zhou, Y.X, Fang, W, Sun, W, Shi, P, Tian, C.L.
登録日2020-04-26
公開日2020-08-05
実験手法ELECTRON MICROSCOPY (3.82 Å)
主引用文献Single-particle cryo-EM structural studies of the beta2AR-Gs complex bound with a full agonist formoterol.
Cell Discov, 6, 2020
1TG8
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BU of 1tg8 by Molmil
The structure of Dengue virus E glycoprotein
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, envelope glycoprotein
著者Zhang, Y, Zhang, W, Ogata, S, Clements, D, Strauss, J.H, Baker, T.S, Rossmann, M.G.
登録日2004-05-28
公開日2004-09-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Conformational changes of the flavivirus e glycoprotein
Structure, 12, 2004
1THD
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BU of 1thd by Molmil
COMPLEX ORGANIZATION OF DENGUE VIRUS E PROTEIN AS REVEALED BY 9.5 ANGSTROM CRYO-EM RECONSTRUCTION
分子名称: Major envelope protein E
著者Zhang, Y, Zhang, W, Ogata, S, Clements, D, Strauss, J.H, Baker, T.S, Kuhn, R.J, Rossmann, M.G.
登録日2004-06-01
公開日2004-09-28
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (9.5 Å)
主引用文献Conformational changes of the flavivirus e glycoprotein
Structure, 12, 2004
1TGE
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BU of 1tge by Molmil
The structure of immature Dengue virus at 12.5 angstrom
分子名称: envelope glycoprotein
著者Zhang, Y, Zhang, W, Ogata, S, Clements, D, Strauss, J.H, Baker, T.S, Kuhn, R.J, Rossmann, M.G.
登録日2004-05-28
公開日2004-09-28
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (12.5 Å)
主引用文献Conformational changes of the flavivirus e glycoprotein.
Structure, 12, 2004
4R7I
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BU of 4r7i by Molmil
Crystal structure of FMS kinase domain with a small molecular inhibitor, GLEEVEC
分子名称: 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Macrophage colony-stimulating factor 1 receptor
著者Zhang, Y, Zhang, C.
登録日2014-08-27
公開日2015-08-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor.
N Engl J Med, 373, 2015
5VAI
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BU of 5vai by Molmil
Cryo-EM structure of the activated Glucagon-like peptide-1 receptor in complex with G protein
分子名称: Glucagon-like peptide 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhang, Y, Sun, B, Feng, D, Hu, H, Chu, M, Qu, Q, Tarrasch, J.T, Li, S, Kobilka, T.S, Kobilka, B.K, Skiniotis, G.
登録日2017-03-27
公開日2017-05-24
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein.
Nature, 546, 2017
5V22
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BU of 5v22 by Molmil
Crystal structure of human SETD2 SET-domain in complex with H3K36M peptide and SAH
分子名称: Histone H3K36M peptide, Histone-lysine N-methyltransferase SETD2, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Zhang, Y, Tong, L.
登録日2017-03-02
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis for the role of oncogenic histone mutations in modulating H3K36 methylation.
Sci Rep, 7, 2017
8INK
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BU of 8ink by Molmil
human nuclear pre-60S ribosomal particle - State D
分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Zhang, Y, Gao, N.
登録日2023-03-10
公開日2023-08-09
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
Cell Res., 33, 2023
8IPX
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BU of 8ipx by Molmil
human nuclear pre-60S ribosomal particle - State C'
分子名称: 28S rRNA, 5.8S rRNA, 5S RNA, ...
著者Zhang, Y, Gao, N.
登録日2023-03-15
公開日2023-08-09
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
Cell Res., 33, 2023
8IE3
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BU of 8ie3 by Molmil
human nuclear pre-60S ribosomal particle - State E
分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Zhang, Y, Gao, N.
登録日2023-02-15
公開日2023-08-09
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
Cell Res., 33, 2023
8IR3
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BU of 8ir3 by Molmil
human nuclear pre-60S ribosomal particle - State B'
分子名称: 28S rRNA, 5.8S rRNA, 5S RNA, ...
著者Zhang, Y, Gao, N.
登録日2023-03-17
公開日2023-08-09
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
Cell Res., 33, 2023
8INE
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BU of 8ine by Molmil
human nuclear pre-60S ribosomal particle - State G'
分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Zhang, Y, Gao, N.
登録日2023-03-09
公開日2023-08-09
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
Cell Res., 33, 2023

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