7N1Q
 
 | | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhang, J, Cai, Y.F, Xiao, T.S, Rawson, S, Peng, H.Q, Sterling, S.M, Walsh Jr, R.M, Volloch, S.R, Chen, B. | | 登録日 | 2021-05-28 | | 公開日 | 2021-07-07 | | 最終更新日 | 2021-08-18 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants.
Science, 373, 2021
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5D7D
 | | Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a ligand | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 7-propyl-3-[2-(pyridin-3-yl)-1,3-thiazol-5-yl]-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one, CHLORIDE ION, ... | | 著者 | Zhang, J, Yang, Q, Cross, J.B, Romero, J.A.C, Ryan, M.D, Lippa, B, Dolle, R.E, Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C. | | 登録日 | 2015-08-13 | | 公開日 | 2015-11-11 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Discovery of Indazole Derivatives as a Novel Class of Bacterial Gyrase B Inhibitors.
Acs Med.Chem.Lett., 6, 2015
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5D7R
 | | Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a ligand | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-hydroxy-5-[5-(6-hydroxy-7-propyl-2H-indazol-3-yl)-1,3-thiazol-2-yl]pyridine-2-carboxylic acid, CHLORIDE ION, ... | | 著者 | Zhang, J, Yang, Q, Cross, J.B, Romero, J.A.C, Ryan, M.D, Lippa, B, Dolle, R.E, Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C. | | 登録日 | 2015-08-14 | | 公開日 | 2015-11-18 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Discovery of Indazole Derivatives as a Novel Class of Bacterial Gyrase B Inhibitors.
Acs Med.Chem.Lett., 6, 2015
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6WPI
 | | Crystal structure of Nop9 in complex with ITS1 RNA | | 分子名称: | 3,3',3''-phosphanetriyltripropanoic acid, GLYCEROL, Nucleolar protein 9, ... | | 著者 | Zhang, J, Qiu, C, Hall, T.M.T. | | 登録日 | 2020-04-27 | | 公開日 | 2020-05-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | | 主引用文献 | Nop9 recognizes structured and single-stranded RNA elements of preribosomal RNA.
Rna, 26, 2020
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7N98
 | | Cryo-EM structure of MFSD2A | | 分子名称: | Sodium-dependent lysophosphatidylcholine symporter 1 | | 著者 | Zhang, J, Feng, L. | | 登録日 | 2021-06-17 | | 公開日 | 2021-08-04 | | 最終更新日 | 2021-09-01 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure and mechanism of blood-brain-barrier lipid transporter MFSD2A.
Nature, 596, 2021
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4XNR
 | | Vibrio Vulnificus Adenine Riboswitch Aptamer Domain, Synthesized by Position-selective Labeling of RNA (PLOR), in Complex with Adenine | | 分子名称: | ADENINE, MAGNESIUM ION, Vibrio Vulnificus Adenine Riboswitch | | 著者 | Zhang, J, Liu, Y, Wang, Y.-X, Ferre-D'Amare, A.R. | | 登録日 | 2015-01-16 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Synthesis and applications of RNAs with position-selective labelling and mosaic composition.
Nature, 522, 2015
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5JR9
 | | Crystal structure of apo-NeC3PO | | 分子名称: | NEQ131 | | 著者 | Zhang, J, Gan, J. | | 登録日 | 2016-05-06 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for single-stranded RNA recognition and cleavage by C3PO
Nucleic Acids Res., 44, 2016
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8FHN
 | | Cryo-EM structure of human NCC (class 2) | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Polythiazide, Solute carrier family 12 member 2,Solute carrier family 12 member 3 chimera | | 著者 | Zhang, J, Fan, M, Feng, L. | | 登録日 | 2022-12-14 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
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8FHO
 | | Cryo-EM structure of human NCC (class 1) | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Polythiazide, SODIUM ION, ... | | 著者 | Zhang, J, Fan, M, Feng, L. | | 登録日 | 2022-12-14 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
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8FHR
 | | Cryo-EM structure of human NCC (class 3-3) | | 分子名称: | Polythiazide, SODIUM ION, Solute carrier family 12 member 2,Solute carrier family 12 member 3 chimera | | 著者 | Zhang, J, Fan, M, Feng, L. | | 登録日 | 2022-12-14 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
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8FHP
 | | Cryo-EM structure of human NCC (class 3-1) | | 分子名称: | Polythiazide, SODIUM ION, Solute carrier family 12 member 2,Solute carrier family 12 member 3 chimera | | 著者 | Zhang, J, Fan, M, Feng, L. | | 登録日 | 2022-12-14 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
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8FHT
 | | Cryo-EM structure of human NCC | | 分子名称: | CHLORIDE ION, SODIUM ION, Solute carrier family 12 member 3 | | 著者 | Zhang, J, Fan, M, Feng, L. | | 登録日 | 2022-12-15 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
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8FHQ
 | | Cryo-EM structure of human NCC (class 3-2) | | 分子名称: | Polythiazide, SODIUM ION, Solute carrier family 12 member 2,Solute carrier family 12 member 3 chimera | | 著者 | Zhang, J, Fan, M, Feng, L. | | 登録日 | 2022-12-14 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | | 主引用文献 | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
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5JRC
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3J03
 | | Lidless Mm-cpn in the closed state with ATP/AlFx | | 分子名称: | Lidless Mm-cpn | | 著者 | Zhang, J, Ma, B, DiMaio, F, Douglas, N.R, Joachimiak, L, Baker, D, Frydman, J, Levitt, M, Chiu, W. | | 登録日 | 2011-02-10 | | 公開日 | 2011-05-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Cryo-EM structure of a group II chaperonin in the prehydrolysis ATP-bound state leading to lid closure.
Structure, 19, 2011
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5DLK
 | | The crystal structure of CT mutant | | 分子名称: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, TqaA | | 著者 | Zhang, J.R, Tang, Y, Zhou, J.H. | | 登録日 | 2015-09-06 | | 公開日 | 2016-09-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis of nonribosomal peptide macrocyclization in fungi
Nat.Chem.Biol., 12, 2016
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7M5D
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7YFF
 | | Structure of GluN1a-GluN2D NMDA receptor in complex with agonist glycine and competitive antagonist CPP. | | 分子名称: | (2R)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhang, J.L, Zhu, S.J, Zhang, M. | | 登録日 | 2022-07-08 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-08-02 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023
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7YFL
 | | Structure of GluN1a-GluN2D NMDA receptor in complex with agonists glycine and glutamate. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | | 著者 | Zhang, J.L, Zhu, S.J, Zhang, M. | | 登録日 | 2022-07-08 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-08-02 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023
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7YFR
 | | Structure of GluN1a E698C-GluN2D NMDA receptor in cystines non-crosslinked state. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | | 著者 | Zhang, J.L, Zhu, S.J, Zhang, M. | | 登録日 | 2022-07-09 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-08-02 | | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | | 主引用文献 | Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023
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5Y2F
 | | Human SIRT6 in complex with allosteric activator MDL-801 | | 分子名称: | 5-[[3,5-bis(chloranyl)phenyl]sulfonylamino]-2-[(5-bromanyl-4-fluoranyl-2-methyl-phenyl)sulfamoyl]benzoic acid, 9-mer peptide QTARKSTGG, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Zhang, J, Huang, Z, Song, K. | | 登録日 | 2017-07-25 | | 公開日 | 2018-11-07 | | 最終更新日 | 2018-11-28 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Identification of a cellularly active SIRT6 allosteric activator.
Nat. Chem. Biol., 14, 2018
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5EJD
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7TO4
 | | Structural and functional impact by SARS-CoV-2 Omicron spike mutations | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhang, J, Xiao, T.S, Cai, Y.F, Peng, H.Q, Volloch, S.R, Chen, B. | | 登録日 | 2022-01-22 | | 公開日 | 2022-02-16 | | 最終更新日 | 2022-05-11 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural and functional impact by SARS-CoV-2 Omicron spike mutations.
Cell Rep, 39, 2022
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7TNW
 | | Structural and functional impact by SARS-CoV-2 Omicron spike mutations | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhang, J, Xiao, T.S, Cai, Y.F, Peng, H.Q, Volloch, S.R, Chen, B. | | 登録日 | 2022-01-21 | | 公開日 | 2022-02-16 | | 最終更新日 | 2022-05-11 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural and functional impact by SARS-CoV-2 Omicron spike mutations.
Cell Rep, 39, 2022
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5DIJ
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