4V6C
 
 | | Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Zhang, W, Dunkle, J.A, Cate, J.H.D. | | 登録日 | 2009-06-27 | | 公開日 | 2014-07-09 | | 最終更新日 | 2014-12-10 | | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | | 主引用文献 | Structures of the ribosome in intermediate States of ratcheting.
Science, 325, 2009
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4M3Q
 | | Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC1917 | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Tyrosine-protein kinase Mer, ... | | 著者 | Zhang, W, Zhang, D, Stashko, M.A, DeRyckere, D, Hunter, D, Kireev, D.B, Miley, M, Cummings, C, Lee, M, Norris-Drouin, J, Stewart, W.M, Sather, S, Zhou, Y, Kirkpatrick, G, Machius, M, Janzen, W.P, Earp, H.S, Graham, D.K, Frye, S, Wang, X. | | 登録日 | 2013-08-06 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.718 Å) | | 主引用文献 | Pseudo-Cyclization through Intramolecular Hydrogen Bond Enables Discovery of Pyridine Substituted Pyrimidines as New Mer Kinase Inhibitors.
J.Med.Chem., 56, 2013
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4MH7
 | | Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC1896 | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, N-butyl-2-(butylamino)-4-[(trans-4-hydroxycyclohexyl)amino]-N-methylpyrimidine-5-carboxamide, ... | | 著者 | Zhang, W, McIver, A, Stashko, M.A, Deryckere, D, Branchford, B.R, Hunter, D, Kireev, D.B, Miley, M.J, Norris-Drouin, J, Stewart, W.M, Lee, M, Sather, S, Zhou, Y, DiPaola, J.A, Machius, M, Janzen, W.P, Earp, H.S, Graham, D.K, Frye, S, Wang, X. | | 登録日 | 2013-08-29 | | 公開日 | 2014-05-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Discovery of Mer specific tyrosine kinase inhibitors for the treatment and prevention of thrombosis.
J.Med.Chem., 56, 2013
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4V6E
 | | Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Zhang, W, Dunkle, J.A, Cate, J.H.D. | | 登録日 | 2009-06-28 | | 公開日 | 2014-07-09 | | 最終更新日 | 2014-12-10 | | 実験手法 | X-RAY DIFFRACTION (3.712 Å) | | 主引用文献 | Structures of the ribosome in intermediate States of ratcheting.
Science, 325, 2009
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4WWA
 | | Crystal structure of binary complex Bud32-Cgi121 | | 分子名称: | EKC/KEOPS complex subunit BUD32, EKC/KEOPS complex subunit CGI121, SULFATE ION | | 著者 | Zhang, W, van Tilbeurgh, H. | | 登録日 | 2014-11-10 | | 公開日 | 2015-03-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.953 Å) | | 主引用文献 | Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex.
Nucleic Acids Res., 43, 2015
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4WQ4
 | | E. coli YgjD(E12A)-YeaZ heterodimer in complex with ATP | | 分子名称: | ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Zhang, W, Collinet, B. | | 登録日 | 2014-10-21 | | 公開日 | 2015-01-28 | | 最終更新日 | 2015-02-25 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | The ATP-mediated formation of the YgjD-YeaZ-YjeE complex is required for the biosynthesis of tRNA t6A in Escherichia coli.
Nucleic Acids Res., 43, 2015
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4WW7
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4WX8
 | | Crystal structure of binary complex Gon7-Pcc1 | | 分子名称: | ACETATE ION, EKC/KEOPS complex subunit GON7, EKC/KEOPS complex subunit PCC1 | | 著者 | Zhang, W, Van Tilbeurgh, H. | | 登録日 | 2014-11-13 | | 公開日 | 2015-03-18 | | 最終更新日 | 2015-04-15 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex.
Nucleic Acids Res., 43, 2015
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4WXA
 | | Crystal structure of binary complex Gon7-Pcc1 | | 分子名称: | ACETATE ION, EKC/KEOPS complex subunit GON7, EKC/KEOPS complex subunit PCC1, ... | | 著者 | Zhang, W, van Tilbeurgh, H. | | 登録日 | 2014-11-13 | | 公開日 | 2015-03-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex.
Nucleic Acids Res., 43, 2015
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6U6J
 | | RNA-monomer complex containing pyrophosphate linkage | | 分子名称: | 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(hydroxy)phosphoryl]guanosine, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G*(DPG))-3') | | 著者 | Zhang, W, Szostak, J.W, Giurgiu, C, Wright, T. | | 登録日 | 2019-08-29 | | 公開日 | 2019-11-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Prebiotically Plausible "Patching" of RNA Backbone Cleavage through a 3'-5' Pyrophosphate Linkage.
J.Am.Chem.Soc., 141, 2019
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6UR2
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4DJG
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6KZI
 | | Crystal structure of Ser/Thr kinase Pim1 in complex with thioridazine derivatives | | 分子名称: | 4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine, Serine/threonine-protein kinase pim-1 | | 著者 | Zhang, W, Wan, X, Li, W, Xie, Y, Huang, N. | | 登録日 | 2019-09-24 | | 公開日 | 2020-03-04 | | 最終更新日 | 2021-03-17 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors.
J.Chem.Inf.Model., 60, 2020
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4V6D
 | | Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Zhang, W, Dunkle, J.A, Cate, J.H.D. | | 登録日 | 2009-06-27 | | 公開日 | 2014-07-09 | | 最終更新日 | 2014-12-10 | | 実験手法 | X-RAY DIFFRACTION (3.814 Å) | | 主引用文献 | Structures of the ribosome in intermediate States of ratcheting.
Science, 325, 2009
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4WQ5
 | | YgjD(V85E)-YeaZ heterodimer in complex with ATP | | 分子名称: | ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, FE (III) ION, ... | | 著者 | Zhang, W. | | 登録日 | 2014-10-21 | | 公開日 | 2015-01-28 | | 最終更新日 | 2015-02-25 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | The ATP-mediated formation of the YgjD-YeaZ-YjeE complex is required for the biosynthesis of tRNA t6A in Escherichia coli.
Nucleic Acids Res., 43, 2015
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1P58
 | | Complex Organization of Dengue Virus Membrane Proteins as Revealed by 9.5 Angstrom Cryo-EM reconstruction | | 分子名称: | Envelope protein M, Major envelope protein E | | 著者 | Zhang, W, Chipman, P.R, Corver, J, Johnson, P.R, Zhang, Y, Mukhopadhyay, S, Baker, T.S, Strauss, J.H, Rossmann, M.G, Kuhn, R.J. | | 登録日 | 2003-04-25 | | 公開日 | 2003-11-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (9.5 Å) | | 主引用文献 | Visualization of membrane protein domains by cryo-electron microscopy of dengue virus
Nat.Struct.Biol., 10, 2003
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4WW5
 | | Crystal structure of binary complex Bud32-Cgi121 in complex with AMPP | | 分子名称: | ACETATE ION, EKC/KEOPS complex subunit BUD32, EKC/KEOPS complex subunit CGI121, ... | | 著者 | Zhang, W. | | 登録日 | 2014-11-10 | | 公開日 | 2015-03-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | | 主引用文献 | Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex.
Nucleic Acids Res., 43, 2015
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4WW9
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4X3X
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6FE8
 | | Cryo-EM structure of the core Centromere Binding Factor 3 complex | | 分子名称: | Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, Suppressor of kinetochore protein 1 | | 著者 | Zhang, W.J, Lukoynova, N, Miah, S, Vaughan, C.K. | | 登録日 | 2017-12-30 | | 公開日 | 2018-08-01 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Insights into Centromere DNA Bending Revealed by the Cryo-EM Structure of the Core Centromere Binding Factor 3 with Ndc10.
Cell Rep, 24, 2018
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6GSA
 | | Core Centromere Binding Factor 3 (CBF3) with monomeric Ndc10 | | 分子名称: | Centromere DNA-binding protein complex CBF3 subunit A, Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, ... | | 著者 | Zhang, W.J, Lukoynova, N, Vaughan, C.K. | | 登録日 | 2018-06-13 | | 公開日 | 2018-08-01 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Insights into Centromere DNA Bending Revealed by the Cryo-EM Structure of the Core Centromere Binding Factor 3 with Ndc10.
Cell Rep, 24, 2018
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4RHD
 | | DNA Duplex with Novel ZP Base Pair | | 分子名称: | DNA 9mer novel P nucleobase, DNA 9mer novel Z nucleobase, MAGNESIUM ION | | 著者 | Zhang, W, Zhang, L, Benner, S, Huang, Z. | | 登録日 | 2014-10-01 | | 公開日 | 2015-07-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Evolution of functional six-nucleotide DNA.
J.Am.Chem.Soc., 137, 2015
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5CB5
 | | Structural Insights into the Mechanism of Escherichia coli Ymdb | | 分子名称: | ACETATE ION, ADENOSINE-5-DIPHOSPHORIBOSE, O-acetyl-ADP-ribose deacetylase, ... | | 著者 | Zhang, W, Wang, C, Song, Y, Shao, C, Zhang, X, Zang, J. | | 登録日 | 2015-06-30 | | 公開日 | 2015-11-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural insights into the mechanism of Escherichia coli YmdB: A 2'-O-acetyl-ADP-ribose deacetylase
J.Struct.Biol., 192, 2015
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5CMS
 | | Structural Insights into the Mechanism of Escherichia coli Ymdb | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, O-acetyl-ADP-ribose deacetylase, SULFATE ION | | 著者 | Zhang, W, Wang, C, Song, Y, Shao, C, Zhang, X, Zang, J. | | 登録日 | 2015-07-17 | | 公開日 | 2015-11-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | | 主引用文献 | Structural insights into the mechanism of Escherichia coli YmdB: A 2'-O-acetyl-ADP-ribose deacetylase
J.Struct.Biol., 192, 2015
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6L15
 | | Crystal structure of Ser/Thr kinase Pim1 in complex with 10-DEBC derivatives | | 分子名称: | 7-chloranyl-5-[3-[(3~{S})-piperidin-3-yl]propyl]pyrido[3,4-b][1,4]benzoxazine, Serine/threonine-protein kinase pim-1 | | 著者 | Zhang, W, Xie, Y, Cao, R, Huang, N, Zhou, Y. | | 登録日 | 2019-09-27 | | 公開日 | 2020-05-27 | | 最終更新日 | 2020-07-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors.
J.Chem.Inf.Model., 60, 2020
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