5XZO
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![BU of 5xzo by Molmil](/molmil-images/mine/5xzo) | Crystal structure of GH10 xylanase XYL10C from Bispora. sp MEY-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-xylanase | Authors: | You, S, Chen, C, Tu, T, Guo, R.T, Luo, H, Yao, B. | Deposit date: | 2017-07-13 | Release date: | 2018-01-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of GH10 xylanase XYL10C from Bispora. sp MEY-1 To Be Published
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5XZU
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![BU of 5xzu by Molmil](/molmil-images/mine/5xzu) | Crystal structure of GH10 xylanase from Bispora. sp MEY-1 with xylobiose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-xylanase, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | Authors: | You, S, Chen, C.C, Tu, T, Guo, R.T, Luo, H.Y, Yao, B. | Deposit date: | 2017-07-14 | Release date: | 2018-05-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Insight into the functional roles of Glu175 in the hyperthermostable xylanase XYL10C-Delta N through structural analysis and site-saturation mutagenesis. Biotechnol Biofuels, 11, 2018
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5H7D
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![BU of 5h7d by Molmil](/molmil-images/mine/5h7d) | Crystal structure of the YgjG-protein A-Zpa963-calmodulin complex | Descriptor: | CALCIUM ION, Putrescine aminotransferase,Immunoglobulin G-binding protein A, Zpa963,Calmodulin | Authors: | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | Deposit date: | 2016-11-17 | Release date: | 2017-06-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method. Sci Rep, 7, 2017
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5X3F
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![BU of 5x3f by Molmil](/molmil-images/mine/5x3f) | Crystal structure of the YgjG-Protein A-Zpa963-PKA catalytic domain | Descriptor: | Putrescine aminotransferase,Immunoglobulin G-binding protein A, Zpa963,cAMP-dependent protein kinase catalytic subunit alpha | Authors: | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | Deposit date: | 2017-02-05 | Release date: | 2017-06-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.38 Å) | Cite: | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method. Sci Rep, 7, 2017
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5H7A
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![BU of 5h7a by Molmil](/molmil-images/mine/5h7a) | Crystal structure of a repeat protein with four Protein A repeat module | Descriptor: | Immunoglobulin G-binding protein A | Authors: | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | Deposit date: | 2016-11-17 | Release date: | 2017-06-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method. Sci Rep, 7, 2017
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5H75
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![BU of 5h75 by Molmil](/molmil-images/mine/5h75) | Crystal structure of the MrsD-Protein A fusion protein | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Mersacidin decarboxylase,Immunoglobulin G-binding protein A | Authors: | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | Deposit date: | 2016-11-17 | Release date: | 2017-06-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.738 Å) | Cite: | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method. Sci Rep, 7, 2017
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5H7B
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![BU of 5h7b by Molmil](/molmil-images/mine/5h7b) | Crystal structure of a repeat protein with five Protein A repeat modules | Descriptor: | Immunoglobulin G-binding protein A | Authors: | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | Deposit date: | 2016-11-17 | Release date: | 2017-06-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method. Sci Rep, 7, 2017
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5H79
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![BU of 5h79 by Molmil](/molmil-images/mine/5h79) | Crystal structure of a repeat protein with three Protein A repeat module | Descriptor: | Immunoglobulin G-binding protein A | Authors: | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | Deposit date: | 2016-11-17 | Release date: | 2017-06-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method. Sci Rep, 7, 2017
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5H78
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![BU of 5h78 by Molmil](/molmil-images/mine/5h78) | Crystal structure of the PKA-DHR14 fusion protein | Descriptor: | cAMP-dependent protein kinase type II-alpha regulatory subunit,DHR14 | Authors: | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | Deposit date: | 2016-11-17 | Release date: | 2017-06-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.002 Å) | Cite: | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method. Sci Rep, 7, 2017
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5H7C
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![BU of 5h7c by Molmil](/molmil-images/mine/5h7c) | Crystal structure of a repeat protein with two Protein A-DHR14 repeat modules | Descriptor: | Immunoglobulin G-binding protein A, DHR14 | Authors: | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | Deposit date: | 2016-11-17 | Release date: | 2017-06-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method. Sci Rep, 7, 2017
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5H76
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![BU of 5h76 by Molmil](/molmil-images/mine/5h76) | Crystal structure of the DARPin-Protein A fusion protein | Descriptor: | DARPin,Immunoglobulin G-binding protein A | Authors: | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | Deposit date: | 2016-11-17 | Release date: | 2017-06-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method. Sci Rep, 7, 2017
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5XBY
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![BU of 5xby by Molmil](/molmil-images/mine/5xby) | Crystal structure of the PKA-Protein A fusion protein (end-to-end fusion) | Descriptor: | cAMP-dependent protein kinase type II-alpha regulatory subunit,Immunoglobulin G-binding protein A | Authors: | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | Deposit date: | 2017-03-21 | Release date: | 2017-07-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method. Sci Rep, 7, 2017
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5H77
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![BU of 5h77 by Molmil](/molmil-images/mine/5h77) | Crystal structure of the PKA-protein A fusion protein | Descriptor: | cAMP-dependent protein kinase type II-alpha regulatory subunit,Immunoglobulin G-binding protein A | Authors: | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | Deposit date: | 2016-11-17 | Release date: | 2017-06-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.197 Å) | Cite: | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method. Sci Rep, 7, 2017
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8Y83
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![BU of 8y83 by Molmil](/molmil-images/mine/8y83) | |
8Y7R
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![BU of 8y7r by Molmil](/molmil-images/mine/8y7r) | |
7A9E
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![BU of 7a9e by Molmil](/molmil-images/mine/7a9e) | tRNA-guanine transglycosylase C158S/C281S/Y330C/H333A mutant in complex with ethyl methyl sulfone | Descriptor: | 1,2-ETHANEDIOL, 1-methylsulfonylethane, GLYCEROL, ... | Authors: | Nguyen, D, You, S, Heine, A, Klebe, G. | Deposit date: | 2020-09-01 | Release date: | 2021-06-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Targeting a Cryptic Pocket in a Protein-Protein Contact by Disulfide-Induced Rupture of a Homodimeric Interface. Acs Chem.Biol., 16, 2021
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7ADN
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![BU of 7adn by Molmil](/molmil-images/mine/7adn) | apo tRNA-guanine transglycosylase C158S/C281S/Y330C/H333A mutant | Descriptor: | FORMIC ACID, GLYCEROL, Queuine tRNA-ribosyltransferase, ... | Authors: | Nguyen, D, You, S, Heine, A, Klebe, G. | Deposit date: | 2020-09-15 | Release date: | 2021-06-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Targeting a Cryptic Pocket in a Protein-Protein Contact by Disulfide-Induced Rupture of a Homodimeric Interface. Acs Chem.Biol., 16, 2021
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5B6K
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![BU of 5b6k by Molmil](/molmil-images/mine/5b6k) | |
1EB2
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![BU of 1eb2 by Molmil](/molmil-images/mine/1eb2) | Trypsin inhibitor complex (BPO) | Descriptor: | 3-[(Z)-AMINO(IMINO)METHYL]-N-[2-(4-BENZOYL-1-PIPERIDINYL)-2-OXO-1-PHENYLETHYL]BENZAMIDE, CALCIUM ION, SULFATE ION, ... | Authors: | Wilkinson, K.W, Young, S.C, Liebeschuetz, J.W, Brady, R.L. | Deposit date: | 2001-07-18 | Release date: | 2002-02-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Pro_Select: Combining Structure-Based Drug Design and Array-Based Chemistry for Rapid Lead Discovery. 2. The Development of a Series of Highly Potent and Selective Factor Xa Inhibitors J.Med.Chem., 45, 2002
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4B6L
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![BU of 4b6l by Molmil](/molmil-images/mine/4b6l) | Discovery of Oral Polo-Like Kinase (PLK) Inhibitors with Enhanced Selectivity Profile using Residue Targeted Drug Design | Descriptor: | 4-[[(4R)-5-cyclopentyl-4-ethyl-3a,4-dihydro-3H-[1,2,4]triazolo[4,3-f]pteridin-7-yl]amino]-N-cyclopropyl-3-methoxy-benzamide, SERINE/THREONINE-PROTEIN KINASE PLK3, SULFATE ION | Authors: | Brown, K, Charrier, J.D, Durrant, S, Griffiths, M, Hudson, C, Kay, D, Knegtel, R, ODonnell, M, Pierard, F, Twin, H, Weber, P, Young, S. | Deposit date: | 2012-08-14 | Release date: | 2013-08-21 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery of Oral Polo-Like Kinase (Plk) Inhibitors with Enhanced Selectivity Profile Using Residue Targeted Drug Design To be Published
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5GS1
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![BU of 5gs1 by Molmil](/molmil-images/mine/5gs1) | Crystal structure of homo-specific diabody | Descriptor: | diabody, heavy chain, light chain | Authors: | Kim, J.H, Song, D.H, Youn, S.J, Kim, J.W, Cho, G, Lee, H, Lee, J.O. | Deposit date: | 2016-08-13 | Release date: | 2016-10-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface. Sci Rep, 6, 2016
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5GS0
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![BU of 5gs0 by Molmil](/molmil-images/mine/5gs0) | Crystal structure of the complex of TLR3 and bi-specific diabody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 3, alpha-D-mannopyranose, ... | Authors: | Kim, J.H, Song, D.H, Youn, S.J, Kim, J.W, Cho, G, Lee, H, Lee, J.O. | Deposit date: | 2016-08-13 | Release date: | 2016-10-12 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.275 Å) | Cite: | Crystal structure of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface. Sci Rep, 6, 2016
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5GS2
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![BU of 5gs2 by Molmil](/molmil-images/mine/5gs2) | Crystal structure of diabody complex with repebody and MBP | Descriptor: | Maltose-binding periplasmic protein, anti-MBP, anti-repebody, ... | Authors: | Kim, J.H, Song, D.H, Youn, S.J, Kim, J.W, Cho, G, Lee, H, Lee, J.O. | Deposit date: | 2016-08-13 | Release date: | 2016-10-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.592 Å) | Cite: | Crystal structure of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface. Sci Rep, 6, 2016
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6WN4
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![BU of 6wn4 by Molmil](/molmil-images/mine/6wn4) | Structural basis for the binding of monoclonal antibody 5D2 to the tryptophan-rich lipid-binding loop in lipoprotein lipase | Descriptor: | 5D2 FAB HEAVY CHAIN, 5D2 FAB LIGHT CHAIN, Lipoprotein lipase peptide | Authors: | Luz, J.G, Birrane, G, Young, S.G, Meiyappan, M, Ploug, M. | Deposit date: | 2020-04-22 | Release date: | 2020-07-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase. J.Lipid Res., 61, 2020
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5GRY
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![BU of 5gry by Molmil](/molmil-images/mine/5gry) | Crystal structure of disulfide-bonded diabody | Descriptor: | diabody | Authors: | Kim, J.H, Song, D.H, Youn, S.J, Kim, J.W, Cho, G, Lee, H, Lee, J.O. | Deposit date: | 2016-08-12 | Release date: | 2016-10-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.639 Å) | Cite: | Crystal structure of mono- and bi-specific diabodies and reduction of their structural flexibility by introduction of disulfide bridges at the Fv interface. Sci Rep, 6, 2016
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