4E80
| Structural Basis for the Activity of a Cytoplasmic RNA Terminal U-transferase | Descriptor: | Poly(A) RNA polymerase protein cid1, URIDINE 5'-TRIPHOSPHATE | Authors: | Yates, L.A, Fleurdepine, S, Rissland, O.S, DeColibus, L, Harlos, K, Norbury, C.J, Gilbert, R.J.C. | Deposit date: | 2012-03-19 | Release date: | 2012-07-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.02 Å) | Cite: | Structural basis for the activity of a cytoplasmic RNA terminal uridylyl transferase. Nat.Struct.Mol.Biol., 19, 2012
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4E8F
| Structural Basis for the Activity of a Cytoplasmic RNA Terminal U-transferase | Descriptor: | ACETATE ION, GLYCEROL, Poly(A) RNA polymerase protein cid1 | Authors: | Yates, L.A, Fleurdepine, S, Rissland, O.S, DeColibus, L, Harlos, K, Norbury, C.J, Gilbert, R.J.C. | Deposit date: | 2012-03-20 | Release date: | 2012-07-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for the activity of a cytoplasmic RNA terminal uridylyl transferase. Nat.Struct.Mol.Biol., 19, 2012
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4E7X
| Structural Basis for the Activity of a Cytoplasmic RNA Terminal U-transferase | Descriptor: | ACETATE ION, Poly(A) RNA polymerase protein cid1 | Authors: | Yates, L.A, Fleurdepine, S, Rissland, O.S, DeColibus, L, Harlos, K, Norbury, C.J, Gilbert, R.J.C. | Deposit date: | 2012-03-19 | Release date: | 2012-07-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for the activity of a cytoplasmic RNA terminal uridylyl transferase. Nat.Struct.Mol.Biol., 19, 2012
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6I52
| Yeast RPA bound to ssDNA | Descriptor: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Replication factor A protein 1, Replication factor A protein 2, ... | Authors: | Yates, L.A, Aramayo, R.J, Zhang, X. | Deposit date: | 2018-11-12 | Release date: | 2018-12-19 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA. Nat Commun, 9, 2018
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8B4J
| Rfa1-N-terminal domain in complex with phosphorylated Ddc2 | Descriptor: | 1,2-ETHANEDIOL, DNA damage checkpoint protein LCD1, Replication factor A protein 1, ... | Authors: | Yates, L.A, Zhang, X. | Deposit date: | 2022-09-20 | Release date: | 2023-09-27 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | A DNA damage-induced phosphorylation circuit enhances Mec1 ATR Ddc2 ATRIP recruitment to Replication Protein A. Proc.Natl.Acad.Sci.USA, 120, 2023
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8B4K
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6S8F
| Structure of nucleotide-bound Tel1/ATM | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1 | Authors: | Yates, L.A, Williams, R.M, Ayala, R, Zhang, X. | Deposit date: | 2019-07-09 | Release date: | 2019-10-30 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM Structure of Nucleotide-Bound Tel1ATMUnravels the Molecular Basis of Inhibition and Structural Rationale for Disease-Associated Mutations. Structure, 28, 2020
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4UD4
| Structural Plasticity of Cid1 Provides a Basis for its RNA Terminal Uridylyl Transferase Activity | Descriptor: | GLYCEROL, POLY(A) RNA POLYMERASE PROTEIN CID1 | Authors: | Yates, L.A, Durrant, B.P, Fleurdepine, S, Harlos, K, Norbury, C.J, Gilbert, R.J.C. | Deposit date: | 2014-12-07 | Release date: | 2015-03-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structural plasticity of Cid1 provides a basis for its distributive RNA terminal uridylyl transferase activity. Nucleic Acids Res., 43, 2015
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4UD5
| Structural Plasticity of Cid1 Provides a Basis for its RNA Terminal Uridylyl Transferase Activity | Descriptor: | POLY(A) RNA POLYMERASE PROTEIN CID1 | Authors: | Yates, L.A, Durrant, B.P, Fleurdepine, S, Harlos, K, Norbury, C.J, Gilbert, R.J.C. | Deposit date: | 2014-12-07 | Release date: | 2015-03-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Structural Plasticity of Cid1 Provides a Basis for its Distributive RNA Terminal Uridylyl Transferase Activity. Nucleic Acids Res., 43, 2015
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4BBK
| Structural and functional characterisation of the kindlin-1 pleckstrin homology domain | Descriptor: | FERMITIN FAMILY HOMOLOG 1, GLYCEROL | Authors: | Yates, L.A, Lumb, C.N, Brahme, N.N, Zalyte, R, Bird, L.E, De Colibus, L, Owens, R.J, Calderwood, D.A, Sansom, M.S.P, Gilbert, R.J.C. | Deposit date: | 2012-09-25 | Release date: | 2012-11-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and Functional Characterisation of the Kindlin-1 Pleckstrin Homology Domain J.Biol.Chem., 287, 2012
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6Z3A
| Mec1-Ddc2 (wild-type) in complex with AMP-PNP | Descriptor: | DNA damage checkpoint protein LCD1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase MEC1, ... | Authors: | Yates, L.A, Zhang, X. | Deposit date: | 2020-05-19 | Release date: | 2020-11-11 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase. Nat.Struct.Mol.Biol., 28, 2021
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6Z2X
| Mec1-Ddc2 (F2244L mutant) in complex with Mg AMP-PNP (State II) | Descriptor: | DNA damage checkpoint protein LCD1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Yates, L.A, Zhang, X. | Deposit date: | 2020-05-18 | Release date: | 2020-11-11 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase. Nat.Struct.Mol.Biol., 28, 2021
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6Z2W
| Mec1-Ddc2 (F2244L mutant) in complex with Mg AMP-PNP | Descriptor: | DNA damage checkpoint protein LCD1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Yates, L.A, Zhang, X. | Deposit date: | 2020-05-18 | Release date: | 2020-11-11 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.82 Å) | Cite: | Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase. Nat.Struct.Mol.Biol., 28, 2021
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8R64
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