5W6M
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4ROU
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4NSD
| Crystal Structure of CBARA1 in the Ca2+ Binding Form | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Wang, L, Yang, X, Li, S, Shen, Y. | 登録日 | 2013-11-28 | 公開日 | 2014-02-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake. Embo J., 33, 2014
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7E5Y
| Molecular basis for neutralizing antibody 2B11 targeting SARS-CoV-2 RBD | 分子名称: | 2B11 Fab Heavy chain, 2B11 Fab Light chain, Spike protein S1 | 著者 | Wu, H, Yu, F, Wang, Q.S, Zhou, H, Wang, W.W, Zhao, T, Pan, Y.B, Yang, X.M. | 登録日 | 2021-02-21 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.59 Å) | 主引用文献 | Screening of potent neutralizing antibodies against SARS-CoV-2 using convalescent patients-derived phage-display libraries. Cell Discov, 7, 2021
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8HNV
| CryoEM structure of HpaCas9-sgRNA-dsDNA in the presence of AcrIIC4 | 分子名称: | CRISPR-associated endonuclease Cas9, anti-CRISPR protein AcrIIC4, non-target strand, ... | 著者 | Sun, W, Cheng, Z, Wang, J, Yang, X, Wang, Y. | 登録日 | 2022-12-08 | 公開日 | 2023-07-19 | 最終更新日 | 2023-08-02 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation. Proc.Natl.Acad.Sci.USA, 120, 2023
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3Q54
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4O9B
| The Structure of CC1-IH in human STIM1. | 分子名称: | CADMIUM ION, Stromal interaction molecule 1 | 著者 | Cui, B, Yang, X, Li, S, Shen, Y. | 登録日 | 2014-01-02 | 公開日 | 2014-01-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.604 Å) | 主引用文献 | The inhibitory helix controls the intramolecular conformational switching of the C-terminus of STIM1. Plos One, 8, 2013
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2A4G
| Hepatitis C Protease NS3-4A serine protease with Ketoamide Inhibitor SCH225724 Bound | 分子名称: | ({1-[1-CARBAMOYL-PHENYL-METHYL)-CARBAMOYL]-METHYL}-AMINOOXALYL)-BUTYLCARBAMOYL)-3-METHYL-BUTYLCARBAMOYL)-CYCLOHEXYL-METHYL)-CARBAMIC ACID ISOBUTYL ESTER, NS3 protease/helicase, NS4a peptide, ... | 著者 | Arasappan, A, Njoroge, F.G, Chan, T.Y, Bennett, F, Bogen, S.L, Chen, K, Gu, H, Hong, L, Jao, E, Liu, Y.T, Lovey, R.G, Parekh, T, Pike, R.E, Pinto, P, Santhanam, B, Venkatraman, S, Vaccaro, H, Wang, H, Yang, X, Zhu, Z, Mckittrick, B, Saksena, A.K, Girijavallabhan, V, Pichardo, J, Butkiewicz, N, Ingram, R, Malcolm, B, Prongay, A.J, Yao, N, Marten, B, Madison, V, Kemp, S, Levy, O, Lim-Wilby, M, Tamura, S, Ganguly, A.K. | 登録日 | 2005-06-28 | 公開日 | 2006-07-04 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Hepatitis C virus NS3-4a serine protease inhibitors. SAR of P2' moiety with improved potency. Bioorg.Med.Chem.Lett., 15, 2005
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2B05
| Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide | 分子名称: | 14-3-3 protein gamma, peptide | 著者 | Papagrigoriou, E, Elkins, J, Arrowsmith, C, Zhao, Y, Debreczeni, E.J, Edwards, A, Weigelt, J, Doyle, D, von Delft, F, Turnbull, A, Yang, X. | 登録日 | 2005-09-13 | 公開日 | 2005-10-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide TO BE PUBLISHED
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6O76
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4NSC
| Crystal Structure of CBARA1 in the Apo-form | 分子名称: | Calcium uptake protein 1, mitochondrial | 著者 | Wang, L, Yang, X, Li, S, Shen, Y. | 登録日 | 2013-11-28 | 公開日 | 2014-02-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake. Embo J., 33, 2014
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6LPI
| Crystal Structure of AHAS holo-enzyme | 分子名称: | Acetolactate synthase isozyme 1 large subunit, Acetolactate synthase isozyme 1 small subunit, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Zhang, Y, Yang, X, Xi, Z, Shen, Y. | 登録日 | 2020-01-10 | 公開日 | 2020-11-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.849 Å) | 主引用文献 | Molecular architecture of the acetohydroxyacid synthase holoenzyme. Biochem.J., 477, 2020
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4R3Q
| Crystal structure of SYCE3 | 分子名称: | Synaptonemal complex central element protein 3 | 著者 | Lu, J, Feng, J, Zhou, W, Yang, X, Shen, Y. | 登録日 | 2014-08-17 | 公開日 | 2014-11-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | Structural insight into the central element assembly of the synaptonemal complex Sci Rep, 4, 2014
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7F3B
| cocrystallization of Escherichia coli dihydrofolate reductase (DHFR) and its pyrrolo[3,2-f]quinazoline inhibitor. | 分子名称: | 7-[(2-fluorophenyl)methyl]pyrrolo[3,2-f]quinazoline-1,3-diamine, Dihydrofolate reductase, GLYCEROL | 著者 | Wang, H, You, X.F, Yang, X.Y, Li, Y, Hong, W. | 登録日 | 2021-06-16 | 公開日 | 2022-04-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | The discovery of 1, 3-diamino-7H-pyrrol[3, 2-f]quinazoline compounds as potent antimicrobial antifolates. Eur.J.Med.Chem., 228, 2022
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1Y2I
| Crystal Structure of MCSG Target APC27401 from Shigella flexneri | 分子名称: | Hypothetical Protein S0862 | 著者 | Brunzelle, J.S, Minasov, G, Yang, X, Shuvalova, L, Collart, F.R, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2004-11-22 | 公開日 | 2005-01-04 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of MCSG Target APC27401 from Shigella flexneri To be Published
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2ARH
| Crystal Structure of a Protein of Unknown Function AQ1966 from Aquifex aeolicus VF5 | 分子名称: | CALCIUM ION, SELENIUM ATOM, SULFATE ION, ... | 著者 | Qiu, Y, Kim, Y, Yang, X, Collart, F, Joachimiak, A, Kossiakoff, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2005-08-19 | 公開日 | 2005-10-04 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Crystal Structure of a Hypothetical Protein Aq_1966 from Aquifex aeolicus VF5 To be Published
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6LYG
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8IP5
| Cryo-EM structure of hMRS2-lowEDTA | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Magnesium transporter MRS2 homolog, ... | 著者 | Li, M, Li, Y, Yang, X, Shen, Y.Q. | 登録日 | 2023-03-14 | 公開日 | 2023-06-14 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Molecular basis of Mg 2+ permeation through the human mitochondrial Mrs2 channel. Nat Commun, 14, 2023
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8IP3
| Cryo-EM structure of hMRS2-Mg | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Magnesium transporter MRS2 homolog, ... | 著者 | Li, M, Li, Y, Yang, X, Shen, Y.Q. | 登録日 | 2023-03-14 | 公開日 | 2023-06-14 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Molecular basis of Mg 2+ permeation through the human mitochondrial Mrs2 channel. Nat Commun, 14, 2023
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8IP6
| Cryo-EM structure of hMRS2-rest | 分子名称: | CHLORIDE ION, Magnesium transporter MRS2 homolog, mitochondrial | 著者 | Li, M, Li, Y, Yang, X, Shen, Y.Q. | 登録日 | 2023-03-14 | 公開日 | 2023-06-14 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Molecular basis of Mg 2+ permeation through the human mitochondrial Mrs2 channel. Nat Commun, 14, 2023
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8IP4
| Cryo-EM structure of hMRS-highEDTA | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Magnesium transporter MRS2 homolog, ... | 著者 | Li, M, Li, Y, Yang, X, Shen, Y.Q. | 登録日 | 2023-03-14 | 公開日 | 2023-06-14 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Molecular basis of Mg 2+ permeation through the human mitochondrial Mrs2 channel. Nat Commun, 14, 2023
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7F6V
| Cryo-EM structure of the human TACAN channel in a closed state | 分子名称: | CHOLESTEROL, Ion channel TACAN | 著者 | Chen, X.Z, Wang, Y.J, Li, Y, Yang, X, Shen, Y.Q. | 登録日 | 2021-06-25 | 公開日 | 2022-02-16 | 最終更新日 | 2022-03-23 | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | 主引用文献 | Cryo-EM structure of the human TACAN in a closed state. Cell Rep, 38, 2022
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2NY7
| HIV-1 gp120 Envelope Glycoprotein Complexed with the Broadly Neutralizing CD4-Binding-Site Antibody b12 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY b12, HEAVY CHAIN, ... | 著者 | Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D. | 登録日 | 2006-11-20 | 公開日 | 2007-02-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature, 445, 2007
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4HVC
| Crystal structure of human prolyl-tRNA synthetase in complex with halofuginone and ATP analogue | 分子名称: | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, Bifunctional glutamate/proline--tRNA ligase, MAGNESIUM ION, ... | 著者 | Zhou, H, Sun, L, Yang, X.L, Schimmel, P. | 登録日 | 2012-11-06 | 公開日 | 2013-01-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | ATP-directed capture of bioactive herbal-based medicine on human tRNA synthetase. Nature, 494, 2012
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4I16
| Crystal structure of CARMA1 CARD | 分子名称: | Caspase recruitment domain-containing protein 11, SULFATE ION | 著者 | Li, S, Yang, X, Shen, Y. | 登録日 | 2012-11-20 | 公開日 | 2012-12-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.751 Å) | 主引用文献 | Structural insights into the assembly of CARMA1 and BCL10 Plos One, 7, 2012
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