7XB2
 
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7WL3
 | | CVB5 expended empty particle | | 分子名称: | Capsid protein, Genome polyprotein | | 著者 | Yang, P, Wang, K. | | 登録日 | 2022-01-12 | | 公開日 | 2022-03-30 | | 最終更新日 | 2022-10-12 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | Atomic Structures of Coxsackievirus B5 Provide Key Information on Viral Evolution and Survival.
J.Virol., 96, 2022
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5X45
 | | Crystal structure of 2A protease from Human rhinovirus C15 | | 分子名称: | ZINC ION, protease 2A | | 著者 | Ling, H, Yang, P, Shaw, N, Sun, Y, Wang, X. | | 登録日 | 2017-02-10 | | 公開日 | 2018-02-21 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | | 主引用文献 | Structural view of the 2A protease from human rhinovirus C15.
Acta Crystallogr.,Sect.F, 74, 2018
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6M5U
 | | The coordinates of the monomeric terminase complex in the presence of the ADP-BeF3 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | 著者 | Yang, Y.X, Yang, P, Wang, N, Zhu, L, Zhou, Z.H, Rao, Z.H, Wang, X.X. | | 登録日 | 2020-03-11 | | 公開日 | 2020-10-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Architecture of the herpesvirus genome-packaging complex and implications for DNA translocation.
Protein Cell, 11, 2020
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6M5S
 | | The coordinates of the apo hexameric terminase complex | | 分子名称: | Tripartite terminase subunit 1, Tripartite terminase subunit 2, Tripartite terminase subunit 3, ... | | 著者 | Yang, Y.X, Yang, P, Wang, N, Chen, Z.H, Zhou, Z.H, Rao, Z.H, Wang, X.X. | | 登録日 | 2020-03-11 | | 公開日 | 2020-10-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Architecture of the herpesvirus genome-packaging complex and implications for DNA translocation.
Protein Cell, 11, 2020
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8HLT
 | | The co-crystal structure of DYRK2 with YK-2-99B | | 分子名称: | (6-{[(4P)-4-(1,3-benzothiazol-5-yl)-5-fluoropyrimidin-2-yl]amino}pyridin-3-yl)(piperazin-1-yl)methanone, Dual specificity tyrosine-phosphorylation-regulated kinase 2 | | 著者 | Shen, H.T, Xiao, Y.B, Yuan, K, Yang, P, Li, Q.N. | | 登録日 | 2022-12-01 | | 公開日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Discovery of Potent DYRK2 Inhibitors with High Selectivity, Great Solubility, and Excellent Safety Properties for the Treatment of Prostate Cancer.
J.Med.Chem., 66, 2023
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7SN2
 | | Structure of human SARS-CoV-2 neutralizing antibody C1C-A3 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Pan, J, Abraham, J, Yang, P, Shankar, S. | | 登録日 | 2021-10-27 | | 公開日 | 2021-12-08 | | 最終更新日 | 2022-02-02 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain.
Science, 375, 2022
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7YUY
 | | Structure of a mutated membrane-bound glycosyltransferase | | 分子名称: | (11R,14S)-17-amino-14-hydroxy-8,14-dioxo-9,13,15-trioxa-14lambda~5~-phosphaheptadecan-11-yl decanoate, 1,3-beta-glucan synthase component FKS1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Hu, X.L, Yang, P, Zhang, M, Liu, X.T, Yu, H.J. | | 登録日 | 2022-08-18 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-04-19 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural and mechanistic insights into fungal beta-1,3-glucan synthase FKS1.
Nature, 616, 2023
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6M5T
 | | The coordinate of the nuclease domain of the apo terminase complex | | 分子名称: | Tripartite terminase subunit 3 | | 著者 | Yang, Y.X, Yang, P, Wang, N, Chen, Z.H, Zhou, Z.H, Rao, Z.H, Wang, X.X. | | 登録日 | 2020-03-11 | | 公開日 | 2020-10-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Architecture of the herpesvirus genome-packaging complex and implications for DNA translocation.
Protein Cell, 11, 2020
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6M5V
 | | The coordinate of the hexameric terminase complex in the presence of the ADP-BeF3 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | 著者 | Yang, Y.X, Yang, P, Wang, N, Chen, Z.H, Zhou, Z.H, Rao, Z.H, Wang, X.X. | | 登録日 | 2020-03-11 | | 公開日 | 2020-10-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Architecture of the herpesvirus genome-packaging complex and implications for DNA translocation.
Protein Cell, 11, 2020
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6M5R
 | | The coordinates of the apo monomeric terminase complex | | 分子名称: | Tripartite terminase subunit 1, Tripartite terminase subunit 2, Tripartite terminase subunit 3, ... | | 著者 | Yang, Y.X, Yang, P, Wang, N, Chen, Z.H, Zhou, Z.H, Rao, Z.H, Wang, X.X. | | 登録日 | 2020-03-11 | | 公開日 | 2020-10-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Architecture of the herpesvirus genome-packaging complex and implications for DNA translocation.
Protein Cell, 11, 2020
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7T4E
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7T4D
 | | Pore structure of pore-forming toxin Epx4 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Epx4 | | 著者 | Xiong, X.Z, Dong, M, Yang, P, Abraham, J. | | 登録日 | 2021-12-09 | | 公開日 | 2022-03-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Emerging enterococcus pore-forming toxins with MHC/HLA-I as receptors.
Cell, 185, 2022
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4Z9P
 | | Crystal structure of Ebola virus nucleoprotein core domain at 1.8A resolution | | 分子名称: | Nucleoprotein | | 著者 | Guo, Y, Dong, S.S, Yang, P, Li, G.B, Liu, B.C, Yang, C, Rao, Z.H. | | 登録日 | 2015-04-11 | | 公開日 | 2015-05-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.792 Å) | | 主引用文献 | Insight into the Ebola virus nucleocapsid assembly mechanism: crystal structure of Ebola virus nucleoprotein core domain at 1.8 A resolution.
Protein Cell, 6, 2015
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5C8C
 | | Crystal structure of recombinant coxsackievirus A16 capsid | | 分子名称: | CHLORIDE ION, POTASSIUM ION, STEARIC ACID, ... | | 著者 | Ren, J, Wang, X, Zhu, L, Hu, Z, Gao, Q, Yang, P, Li, X, Wang, J, Shen, X, Fry, E.E, Rao, Z, Stuart, D.I. | | 登録日 | 2015-06-25 | | 公開日 | 2015-09-30 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity.
J.Virol., 89, 2015
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5C4W
 | | Crystal structure of coxsackievirus A16 | | 分子名称: | CHLORIDE ION, POTASSIUM ION, SODIUM ION, ... | | 著者 | Ren, J, Wang, X, Zhu, L, Hu, Z, Gao, Q, Yang, P, Li, X, Wang, J, Shen, X, Fry, E.E, Rao, Z, Stuart, D.I. | | 登録日 | 2015-06-18 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity.
J.Virol., 89, 2015
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5C9A
 | | Crystal structure of empty coxsackievirus A16 particle | | 分子名称: | CHLORIDE ION, POTASSIUM ION, SPHINGOSINE, ... | | 著者 | Ren, J, Wang, X, Zhu, L, Hu, Z, Gao, Q, Yang, P, Li, X, Wang, J, Shen, X, Fry, E.E, Rao, Z, Stuart, D.I. | | 登録日 | 2015-06-26 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity.
J.Virol., 89, 2015
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6JHR
 | | The cryo-EM structure of HAV bound to a neutralizing antibody-F6 | | 分子名称: | FAB Heavy Chain, FAB Light Chain, VP1, ... | | 著者 | Cao, L, Liu, P, Yang, P, Gao, Q, Li, H, Sun, Y, Zhu, L, Lin, J, Su, D, Rao, Z, Wang, X. | | 登録日 | 2019-02-18 | | 公開日 | 2020-03-18 | | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | | 主引用文献 | Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors.
Plos Biol., 17, 2019
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6JHT
 | | The cryo-EM structure of HAV bound to a neutralizing antibody-F9 | | 分子名称: | FAB Heavy Chain, FAB Light Chain, VP1, ... | | 著者 | Cao, L, Liu, P, Yang, P, Gao, Q, Li, H, Sun, Y, Zhu, L, Lin, J, Su, D, Rao, Z, Wang, X. | | 登録日 | 2019-02-19 | | 公開日 | 2020-03-18 | | 実験手法 | ELECTRON MICROSCOPY (3.79 Å) | | 主引用文献 | Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors.
Plos Biol., 17, 2019
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6JHQ
 | | The cryo-EM structure of HAV bound to a neutralizing antibody-F4 | | 分子名称: | FAB Heavy Chain, FAB Light Chain, VP1, ... | | 著者 | Cao, L, Liu, P, Yang, P, Gao, Q, Li, H, Sun, Y, Zhu, L, Lin, J, Su, D, Rao, Z, Wang, X. | | 登録日 | 2019-02-18 | | 公開日 | 2020-03-18 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors.
Plos Biol., 17, 2019
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6JHS
 | | The cryo-EM structure of HAV bound to a neutralizing antibody-F7 | | 分子名称: | FAB Heavy Chain, FAB Light Chain, VP1, ... | | 著者 | Cao, L, Liu, P, Yang, P, Gao, Q, Li, H, Sun, Y, Zhu, L, Lin, J, Su, D, Rao, Z, Wang, X. | | 登録日 | 2019-02-19 | | 公開日 | 2020-03-18 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors.
Plos Biol., 17, 2019
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5XBM
 | | Structure of SCARB2-JL2 complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysosome membrane protein 2, ... | | 著者 | Zhang, X, Yang, P, Wang, N, Zhang, J, Li, J, Guo, H, Yin, X, Rao, Z, Wang, X, Zhang, L. | | 登録日 | 2017-03-20 | | 公開日 | 2018-06-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.501 Å) | | 主引用文献 | The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection.
Protein Cell, 8, 2017
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5YWO
 | | Structure of JEV-2F2 Fab complex | | 分子名称: | 2F2 heavy chain, 2F2 light chain, JEV E protein, ... | | 著者 | Qiu, X, Lei, Y.F, Yang, P, Gao, Q, Wang, N, Cao, L, Yuan, S, Wang, X, Xu, Z.K, Rao, Z. | | 登録日 | 2017-11-29 | | 公開日 | 2018-03-21 | | 最終更新日 | 2018-09-12 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies
Nat Microbiol, 3, 2018
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5YWP
 | | JEV-2H4 Fab complex | | 分子名称: | 2H4 heavy chain, 2H4 light chain, JEV E protein, ... | | 著者 | Qiu, X.D, Lei, Y.F, Yang, P, Gao, Q, WANG, N, Cao, L, Yuan, S, Wang, X.X, Xu, Z.K, Rao, Z.H. | | 登録日 | 2017-11-29 | | 公開日 | 2018-05-02 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies
Nat Microbiol, 3, 2018
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5YWF
 | | Crystal structure of 2H4 Fab | | 分子名称: | 2H4 heavy chain, 2H4 light chain | | 著者 | Qiu, X, Lei, Y, Yang, P, Gao, Q, Wang, N, Cao, L, Wang, X, Xu, Z.K, Rao, Z. | | 登録日 | 2017-11-29 | | 公開日 | 2018-03-21 | | 実験手法 | X-RAY DIFFRACTION (2.206 Å) | | 主引用文献 | Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies
Nat Microbiol, 3, 2018
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