5YWP

JEV-2H4 Fab complex

Summary for 5YWP

Entry DOI	10.2210/pdb5ywp/pdb
EMDB information	6855
Descriptor	JEV E protein, JEV M protein, 2H4 light chain, ... (4 entities in total)
Functional Keywords	flaviviruses, viral encephalitis, neutralizing monoclonal antibodies, structural analysis, viral entry, immune system
Biological source	Japanese encephalitis virus More
Total number of polymer chains	10
Total formula weight	279632.73
Authors	Qiu, X.D.,Lei, Y.F.,Yang, P.,Gao, Q.,WANG, N.,Cao, L.,Yuan, S.,Wang, X.X.,Xu, Z.K.,Rao, Z.H. (deposition date: 2017-11-29, release date: 2018-05-02)
Primary citation	Qiu, X.,Lei, Y.,Yang, P.,Gao, Q.,Wang, N.,Cao, L.,Yuan, S.,Huang, X.,Deng, Y.,Ma, W.,Ding, T.,Zhang, F.,Wu, X.,Hu, J.,Liu, S.L.,Qin, C.,Wang, X.,Xu, Z.,Rao, Z. Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies Nat Microbiol, 3:287-294, 2018 Cited by PubMed: 29379207 DOI: 10.1038/s41564-017-0099-x PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.6 Å)

Structure validation