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PDB: 514 件

7KQN
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BU of 7kqn by Molmil
Ternary complex of TERT (telomerase reverse transcriptase) with RNA template, DNA primer, an incoming dGTP and a downstream hybrid duplex
分子名称: 1,2-ETHANEDIOL, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
著者Choi, W.S, Weng, P.J, Yang, W.
登録日2020-11-17
公開日2022-03-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Flexibility of telomerase in binding the RNA template and DNA telomeric repeat.
Proc.Natl.Acad.Sci.USA, 119, 2022
7KQM
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BU of 7kqm by Molmil
Binary complex of TERT (telomerase reverse transcriptase) with RNA/telomeric DNA hybrid
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*TP*TP*CP*TP*TP*TP*GP*TP*GP*CP*AP*CP*CP*TP*G)-3'), ...
著者Choi, W.S, Weng, P.J, Yang, W.
登録日2020-11-17
公開日2022-03-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Flexibility of telomerase in binding the RNA template and DNA telomeric repeat.
Proc.Natl.Acad.Sci.USA, 119, 2022
4WWX
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BU of 4wwx by Molmil
Crystal structure of the core RAG1/2 recombinase
分子名称: V(D)J recombination-activating protein 1, V(D)J recombination-activating protein 2, ZINC ION
著者Kim, M.S, Lapkouski, M, Yang, W, Gellert, M.
登録日2014-11-12
公開日2015-02-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.2001 Å)
主引用文献Crystal structure of the V(D)J recombinase RAG1-RAG2.
Nature, 518, 2015
4XVM
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BU of 4xvm by Molmil
Binary complex of human polymerase nu and DNA with the finger domain closed and thumb domain rotated out
分子名称: DNA (5'-D(*CP*TP*AP*GP*CP*GP*TP*CP*A)-3'), DNA (5'-D(*GP*AP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*G)-3'), DNA polymerase nu
著者Lee, Y.-S, Yang, W.
登録日2015-01-27
公開日2015-03-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis.
Nat.Struct.Mol.Biol., 22, 2015
4XVI
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BU of 4xvi by Molmil
Binary complex of human polymerase nu and DNA with the finger domain ajar
分子名称: DNA (5'-D(*AP*CP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*AP*GP*CP*GP*TP*CP*AP*G)-3'), DNA polymerase nu
著者Lee, Y.-S, Yang, W.
登録日2015-01-27
公開日2015-03-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis.
Nat.Struct.Mol.Biol., 22, 2015
4XVK
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BU of 4xvk by Molmil
Binary complex of human polymerase nu and DNA with the finger domain closed
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*GP*AP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*CP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*GP*TP*AP*GP*CP*GP*TP*CP*A)-3'), ...
著者Lee, Y.-S, Yang, W.
登録日2015-01-27
公開日2015-03-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis.
Nat.Struct.Mol.Biol., 22, 2015
4XVL
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BU of 4xvl by Molmil
Binary complex of human polymerase nu and DNA with the finger domain open
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*GP*AP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*TP*AP*GP*CP*GP*TP*CP*A)-3'), ...
著者Lee, Y.-S, Yang, W.
登録日2015-01-27
公開日2015-03-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.301 Å)
主引用文献How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis.
Nat.Struct.Mol.Biol., 22, 2015
6N7T
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BU of 6n7t by Molmil
Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form III)
分子名称: DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ...
著者Gao, Y, Cui, Y, Zhou, Z, Yang, W.
登録日2018-11-28
公開日2019-03-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structures and operating principles of the replisome.
Science, 363, 2019
6N7V
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BU of 6n7v by Molmil
Structure of bacteriophage T7 gp4 (helicase-primase, E343Q mutant) in complex with ssDNA, dTTP, AC dinucleotide, and CTP (from multiple lead complexes)
分子名称: DNA (93-MER), DNA primase/helicase, MAGNESIUM ION, ...
著者Gao, Y, Fox, T, Val, N, Yang, W.
登録日2018-11-28
公開日2019-03-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structures and operating principles of the replisome.
Science, 363, 2019
6N7N
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BU of 6n7n by Molmil
Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form I)
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA primase/helicase, MAGNESIUM ION, ...
著者Gao, Y, Cui, Y, Zhou, Z, Yang, W.
登録日2018-11-27
公開日2019-03-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structures and operating principles of the replisome.
Science, 363, 2019
6N9W
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BU of 6n9w by Molmil
Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS2)
分子名称: DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ...
著者Gao, Y, Cui, Y, Zhou, Z, Yang, W.
登録日2018-12-04
公開日2019-03-06
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structures and operating principles of the replisome.
Science, 363, 2019
6OEQ
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BU of 6oeq by Molmil
Cryo-EM structure of mouse RAG1/2 12RSS-PRC/23RSS-NFC complex (DNA1)
分子名称: CALCIUM ION, DNA (46-MER), DNA (57-MER), ...
著者Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M.
登録日2019-03-27
公開日2020-01-29
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Cutting antiparallel DNA strands in a single active site.
Nat.Struct.Mol.Biol., 27, 2020
6OES
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BU of 6oes by Molmil
Cryo-EM structure of mouse RAG1/2 STC complex (without NBD domain)
分子名称: CALCIUM ION, DNA (34-MER), DNA (35-MER), ...
著者Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M.
登録日2019-03-27
公開日2020-01-22
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献How mouse RAG recombinase avoids DNA transposition.
Nat.Struct.Mol.Biol., 27, 2020
6OEP
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BU of 6oep by Molmil
Cryo-EM structure of mouse RAG1/2 12RSS-NFC/23RSS-PRC complex (DNA1)
分子名称: CALCIUM ION, DNA (46-MER), DNA (57-MER), ...
著者Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M.
登録日2019-03-27
公開日2020-01-29
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cutting antiparallel DNA strands in a single active site.
Nat.Struct.Mol.Biol., 27, 2020
6OEN
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BU of 6oen by Molmil
Cryo-EM structure of mouse RAG1/2 PRC complex (DNA1)
分子名称: CALCIUM ION, DNA (46-MER), DNA (57-MER), ...
著者Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M.
登録日2019-03-27
公開日2020-01-29
最終更新日2020-02-26
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Cutting antiparallel DNA strands in a single active site.
Nat.Struct.Mol.Biol., 27, 2020
6OET
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BU of 6oet by Molmil
Cryo-EM structure of mouse RAG1/2 STC complex
分子名称: CALCIUM ION, DNA (30-MER), DNA (39-MER), ...
著者Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M.
登録日2019-03-27
公開日2020-01-22
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献How mouse RAG recombinase avoids DNA transposition.
Nat.Struct.Mol.Biol., 27, 2020
6OEM
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BU of 6oem by Molmil
Cryo-EM structure of mouse RAG1/2 PRC complex (DNA0)
分子名称: DNA (46-MER), DNA (57-MER), High mobility group protein B1, ...
著者Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M.
登録日2019-03-27
公開日2020-01-29
最終更新日2020-02-26
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cutting antiparallel DNA strands in a single active site.
Nat.Struct.Mol.Biol., 27, 2020
6OER
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BU of 6oer by Molmil
Cryo-EM structure of mouse RAG1/2 NFC complex (DNA2)
分子名称: CALCIUM ION, DNA (46-MER), DNA (57-MER), ...
著者Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M.
登録日2019-03-27
公開日2020-01-29
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Cutting antiparallel DNA strands in a single active site.
Nat.Struct.Mol.Biol., 27, 2020
6N7S
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BU of 6n7s by Molmil
Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form II)
分子名称: DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ...
著者Gao, Y, Cui, Y, Zhou, Z, Yang, W.
登録日2018-11-28
公開日2019-03-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structures and operating principles of the replisome.
Science, 363, 2019
6OZH
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BU of 6ozh by Molmil
Crystal structure of Ciona intestinalis (Ci) Endonuclease V in complex with a 24mer DNA containing an inosine followed by a ribo-adenosine
分子名称: CALCIUM ION, DNA/RNA (5'-D(P*CP*GP*GP*TP*AP*AP*CP*CP*GP*I)-R(P*A)-D(P*TP*AP*TP*GP*CP*AP*GP*CP*AP*TP*TP*TP*C)-3'), endonuclease V isoform X2
著者Samara, N.L, Yang, W.
登録日2019-05-15
公開日2019-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.026 Å)
主引用文献Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell, 76, 2019
6OZJ
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BU of 6ozj by Molmil
Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine in the absence of divalent cation
分子名称: 1,2-ETHANEDIOL, DNA/RNA (5'-R(P*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3'), Endonuclease V, ...
著者Samara, N.L, Yang, W.
登録日2019-05-15
公開日2019-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.247 Å)
主引用文献Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell, 76, 2019
6OZQ
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BU of 6ozq by Molmil
Crystal structure of Mus musculus (Mm) Endonuclease V (K155M) in complex with a 23mer RNA oligo containing an inosine after a 100 min soak in 10 mM Mn2+ and K+
分子名称: 1,2-ETHANEDIOL, DNA/RNA (5'-R(P*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3'), Endonuclease V, ...
著者Samara, N.L, Yang, W.
登録日2019-05-15
公開日2019-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.153 Å)
主引用文献Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell, 76, 2019
6OEO
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BU of 6oeo by Molmil
Cryo-EM structure of mouse RAG1/2 NFC complex (DNA1)
分子名称: CALCIUM ION, DNA (46-MER), DNA (57-MER), ...
著者Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M.
登録日2019-03-27
公開日2020-01-29
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献Cutting antiparallel DNA strands in a single active site.
Nat.Struct.Mol.Biol., 27, 2020
6OZP
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BU of 6ozp by Molmil
Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine after a 180 min soak in 10 mM Mn2+
分子名称: 1,2-ETHANEDIOL, DNA/RNA (5'-R(*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*A)-3'), Endonuclease V, ...
著者Samara, N.L, Yang, W.
登録日2019-05-15
公開日2019-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell, 76, 2019
6OZE
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BU of 6oze by Molmil
Crystal structure of the catalytic domain of human Endonuclease V (C140S/C225S/C226A/C228S)
分子名称: ACETATE ION, Endonuclease V, GLYCEROL, ...
著者Samara, N.L, Yang, W.
登録日2019-05-15
公開日2019-09-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
Mol.Cell, 76, 2019

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件を2024-07-24に公開中

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