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PDB: 8 件

1JV2
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR SEGMENT OF INTEGRIN ALPHAVBETA3
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Xiong, J.P, Stehle, T, Diefenbach, B, Zhang, R, Dunker, R, Scott, D, Joachimiak, A, Goodman, S.L, Arnaout, M.A.
登録日2001-08-28
公開日2001-10-17
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of the extracellular segment of integrin alpha Vbeta3.
Science, 294, 2001
1U8C
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A novel adaptation of the integrin PSI domain revealed from its crystal structure
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Xiong, J.P, Stehle, T, Goodman, S.L, Arnaout, M.A.
登録日2004-08-05
公開日2004-12-28
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A novel adaptation of the integrin PSI domain revealed from its crystal structure.
J.Biol.Chem., 279, 2004
9DEQ
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Cryo-EM structures of full-length integrin alphaIIbbeta3 in native lipids complexed with modified tirofiban
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Adair, B, Xiong, J.P, Yeager, M, Arnaout, M.A.
登録日2024-08-29
公開日2024-10-16
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Platelet integrin alpha IIb beta 3 plays a key role in a venous thrombogenesis mouse model.
Nat Commun, 15, 2024
9DER
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Cryo-EM Structures of Full-Length Integrin alphaIIbbeta3 in Native Lipids Complexed with Tirofiban
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-IIb, ...
著者Adair, B, Xiong, J.P, Yeager, M, Arnaout, M.A.
登録日2024-08-29
公開日2024-10-16
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Platelet integrin alpha IIb beta 3 plays a key role in a venous thrombogenesis mouse model.
Nat Commun, 15, 2024
8T2U
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Cryo-EM Structures of Full-length Integrin alphaIIbbeta3 in Native Lipids complexed with Eptifibatide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Adair, B, Xiong, J.P, Yeager, M, Arnaout, M.A.
登録日2023-06-06
公開日2023-07-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structures of full-length integrin alpha IIb beta 3 in native lipids.
Nat Commun, 14, 2023
8T2V
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Cryo-EM Structures of Full-length Integrin alphaIIbbeta3 in Native Lipids
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Adair, B, Xiong, J.P, Yeager, M, Arnaout, M.A.
登録日2023-06-06
公開日2023-07-26
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures of full-length integrin alpha IIb beta 3 in native lipids.
Nat Commun, 14, 2023
3Q3G
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Crystal Structure of A-domain in complex with antibody
分子名称: 1,2-ETHANEDIOL, Antibody Heavy chain, Antibody Light Chain, ...
著者Mahalingam, B, Xiong, J.P, Arnaout, M.A.
登録日2010-12-21
公開日2011-11-30
最終更新日2011-12-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Stable Coordination of the Inhibitory Ca2+ Ion at the Metal Ion-Dependent Adhesion Site in Integrin CD11b/CD18 by an Antibody-Derived Ligand Aspartate: Implications for Integrin Regulation and Structure-Based Drug Design.
J.Immunol., 187, 2011
3QA3
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Crystal Structure of A-domain in complex with antibody
分子名称: 1,2-ETHANEDIOL, Antibody Heavy chain, Antibody Light chain, ...
著者Mahalingam, B, Xiong, J.P, Arnaout, M.A.
登録日2011-01-10
公開日2011-11-30
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Stable Coordination of the Inhibitory Ca2+ Ion at the Metal Ion-Dependent Adhesion Site in Integrin CD11b/CD18 by an Antibody-Derived Ligand Aspartate: Implications for Integrin Regulation and Structure-Based Drug Design.
J.Immunol., 187, 2011

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件を2024-10-30に公開中

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