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PDB: 12 件
4EHM
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BU of 4ehm by Molmil
RabGGTase in complex with covalently bound Psoromic acid
分子名称: 4-formyl-3-hydroxy-8-methoxy-1,9-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-6-carboxylic acid, CALCIUM ION, Geranylgeranyl transferase type-2 subunit alpha, ...
著者Guo, Z, Deraeve, C, Bon, R.S, Alexandrov, K, Waldmann, H, Wu, Y.W, Goody, R.S, Blankenfeldt, W.
登録日2012-04-02
公開日2012-05-30
最終更新日2017-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Psoromic Acid is a Selective and Covalent Rab-Prenylation Inhibitor Targeting Autoinhibited RabGGTase
J.Am.Chem.Soc., 134, 2012
6Y09
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BU of 6y09 by Molmil
Crystal structure of Atg16L in complex with GTP-bound Rab33B (Q92L)
分子名称: 1,2-ETHANEDIOL, Autophagy-related protein 16-1, DI(HYDROXYETHYL)ETHER, ...
著者Pantoom, S, Wu, Y.W.
登録日2020-02-07
公開日2020-09-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献RAB33B recruits the ATG16L1 complex to the phagophore via a noncanonical RAB binding protein.
Autophagy, 17, 2021
6ZAY
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BU of 6zay by Molmil
Crystal structure of Atg16L in complex with GDP-bound Rab33B
分子名称: 1,2-ETHANEDIOL, Autophagy-related protein 16-1, DI(HYDROXYETHYL)ETHER, ...
著者Pantoom, S, Wu, Y.W.
登録日2020-06-06
公開日2020-09-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献RAB33B recruits the ATG16L1 complex to the phagophore via a noncanonical RAB binding protein.
Autophagy, 17, 2021
5MS5
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BU of 5ms5 by Molmil
Low-salt structure of RavZ LIR2-fused human LC3B
分子名称: GLYCEROL, RavZ,Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION
著者Pantoom, S, Vetter, I.R, Wu, Y.W.
登録日2016-12-31
公開日2017-04-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Elucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins.
Elife, 6, 2017
5MS8
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BU of 5ms8 by Molmil
Crystal structure of the legionella pneumophila effector protein RavZ_1-487
分子名称: BARIUM ION, DI(HYDROXYETHYL)ETHER, Legionella pneumophila effector protein RavZ
著者Pantoom, S, Vetter, I.R, Wu, Y.W.
登録日2016-12-31
公開日2017-04-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Elucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins.
Elife, 6, 2017
5MS6
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BU of 5ms6 by Molmil
High-salt structure of RavZ LIR2-fused human LC3B
分子名称: Microtubule-associated proteins 1A/1B light chain 3B
著者Pantoom, S, Vetter, I.R, Wu, Y.W.
登録日2016-12-31
公開日2017-04-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Elucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins.
Elife, 6, 2017
5MS7
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BU of 5ms7 by Molmil
Crystal structure of the legionella pneumophila effector protein RavZ_20-502
分子名称: BARIUM ION, GLYCEROL, Legionella pneumophila effector protein RavZ
著者Pantoom, S, Vetter, I.R, Wu, Y.W.
登録日2016-12-31
公開日2017-04-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Elucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins.
Elife, 6, 2017
5MS2
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BU of 5ms2 by Molmil
Crystal structure of the Legionella pneumophila effector protein RavZ in complex with human LC3B
分子名称: Legionella pneumophila effector protein RavZ, Microtubule-associated proteins 1A/1B light chain 3B
著者Pantoom, S, Vetter, I.R, Wu, Y.W.
登録日2016-12-30
公開日2017-04-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Elucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins.
Elife, 6, 2017
3C72
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BU of 3c72 by Molmil
Engineered RabGGTase in complex with a peptidomimetic inhibitor
分子名称: CALCIUM ION, Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, ...
著者Guo, Z, Wu, Y.W, Tan, K.T, Bon, R.S, Guiu-Rozas, E, Delon, C, Nguyen, U.T, Wetzel, S, Arndt, S, Goody, R.S, Blankenfeldt, W, Alexandrov, K, Waldmann, H.
登録日2008-02-06
公開日2008-07-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Development of selective RabGGTase inhibitors and crystal structure of a RabGGTase-inhibitor complex.
Angew.Chem.Int.Ed.Engl., 47, 2008
8HIO
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BU of 8hio by Molmil
Cryo-EM structure of the Cas12m2-crRNA binary complex
分子名称: Cas12m2, MAGNESIUM ION, RNA (56-MER), ...
著者Omura, N.S, Nakagawa, R, Wu, Y.W, Sudfeld, C, Warren, V.R, Hirano, H, Kusakizako, T, Kise, Y, Lebbink, H.G.J, Itoh, Y, Oost, V.D.J, Nureki, O.
登録日2022-11-21
公開日2023-04-12
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme.
Nat.Struct.Mol.Biol., 30, 2023
8HHM
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BU of 8hhm by Molmil
Cryo-EM structure of the Cas12m2-crRNA-target DNA ternary complex intermediate state
分子名称: Cas12m2, DNA (36-MER), MAGNESIUM ION, ...
著者Omura, N.S, Nakagawa, R, Wu, Y.W, Sudfeld, C, Warren, V.R, Hirano, H, Kusakizako, T, Kise, Y, Lebbink, H.G.J, Itoh, Y, Oost, V.D.J, Nureki, O.
登録日2022-11-16
公開日2023-04-12
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme.
Nat.Struct.Mol.Biol., 30, 2023
8HHL
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BU of 8hhl by Molmil
Cryo-EM structure of the Cas12m2-crRNA-target DNA full R-loop complex
分子名称: Cas12m2, MAGNESIUM ION, NTS (36-MER), ...
著者Omura, N.S, Nakagawa, R, Wu, Y.W, Sudfeld, C, Warren, V.R, Hirano, H, Kusakizako, T, Kise, Y, Lebbink, H.G.J, Itoh, Y, Oost, V.D.J, Nureki, O.
登録日2022-11-16
公開日2023-04-12
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (2.87 Å)
主引用文献Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme.
Nat.Struct.Mol.Biol., 30, 2023

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件を2024-07-31に公開中

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