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PDB: 27 results

8P0F
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BU of 8p0f by Molmil
Crystal structure of the VCB complex with compound 1.
Descriptor: (3~{R},5~{R})-~{N}-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-5-oxidanyl-2-oxidanylidene-1-pyridin-2-yl-piperidine-3-carboxamide, CHLORIDE ION, Elongin-B, ...
Authors:Bader, G, Boettcher, J, Wolkerstorfer, B.
Deposit date:2023-05-10
Release date:2023-05-31
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Drugit: Crowd-sourcing molecular design of non-peptidic VHL binders
Chemrxiv, 2023
5E1S
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BU of 5e1s by Molmil
The Crystal structure of INSR Tyrosine Kinase in complex with the Inhibitor BI 885578
Descriptor: (5R)-N-(1-{2-[4-(2-methoxyethyl)piperazin-1-yl]ethyl}-1H-pyrazol-3-yl)-5,8-dimethyl-9-phenyl-6,8-dihydro-5H-pyrazolo[3,4-h]quinazolin-2-amine, Insulin receptor
Authors:Kessler, D, Zahn, S, Sanderson, M, Wolkerstorfer, B.
Deposit date:2015-09-30
Release date:2015-10-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.264 Å)
Cite:BI 885578, a Novel IGF1R/INSR Tyrosine Kinase Inhibitor with Pharmacokinetic Properties That Dissociate Antitumor Efficacy and Perturbation of Glucose Homeostasis.
Mol.Cancer Ther., 14, 2015
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数据于2024-06-12公开中

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