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PDB: 80 件

5H84
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Human Gcn5 bound to propionyl-CoA
分子名称: 1,2-ETHANEDIOL, Histone acetyltransferase KAT2A, ISOPROPYL ALCOHOL, ...
著者Wolberger, C, Ringel, A.E.
登録日2015-12-23
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for acyl-group discrimination by human Gcn5L2.
Acta Crystallogr D Struct Biol, 72, 2016
5H86
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BU of 5h86 by Molmil
Human Gcn5 bound to butyryl-CoA
分子名称: 1,2-ETHANEDIOL, Butyryl Coenzyme A, Histone acetyltransferase KAT2A
著者Wolberger, C, Ringel, A.E.
登録日2015-12-23
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structural basis for acyl-group discrimination by human Gcn5L2.
Acta Crystallogr D Struct Biol, 72, 2016
4WA6
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BU of 4wa6 by Molmil
Structure of yeast SAGA DUBm with Sgf73 N59D mutant at 2.36 angstroms resolution
分子名称: SAGA-associated factor 11, SAGA-associated factor 73, Transcription and mRNA export factor SUS1, ...
著者Wolberger, C, Yan, M.
登録日2014-08-28
公開日2015-03-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structure of yeast SAGA DUBm with Sgf73 N59D mutant at 2.36 angstroms resolution
To Be Published
1APL
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BU of 1apl by Molmil
CRYSTAL STRUCTURE OF A MAT-ALPHA2 HOMEODOMAIN-OPERATOR COMPLEX SUGGESTS A GENERAL MODEL FOR HOMEODOMAIN-DNA INTERACTIONS
分子名称: DNA (5'-D(*AP*CP*AP*TP*GP*TP*AP*AP*TP*TP*CP*AP*TP*TP*TP*AP*C P*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*GP*TP*AP*AP*AP*TP*GP*AP*AP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MAT-ALPHA2 HOMEODOMAIN)
著者Wolberger, C, Vershon, A.K, Liu, B, Johnson, A.D, Pabo, C.O.
登録日1993-10-04
公開日1993-10-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of a MAT alpha 2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions.
Cell(Cambridge,Mass.), 67, 1991
4W4U
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BU of 4w4u by Molmil
Structure of yeast SAGA DUBm with Sgf73 Y57A mutant at 2.8 angstroms resolution
分子名称: SAGA-associated factor 11, SAGA-associated factor 73, Transcription and mRNA export factor SUS1, ...
著者Wolberger, C, Yan, M.
登録日2014-08-15
公開日2015-07-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Uncovering the role of Sgf73 in maintaining SAGA deubiquitinating module structure and activity.
J.Mol.Biol., 427, 2015
3PDH
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BU of 3pdh by Molmil
Structure of Sir2Tm bound to a propionylated peptide
分子名称: Cellular tumor antigen p53 18-residue peptide, NAD-dependent deacetylase, ZINC ION
著者Wolberger, C, Bheda, P.
登録日2010-10-22
公開日2011-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of Sir2Tm bound to a propionylated peptide.
Protein Sci., 20, 2011
2GMI
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BU of 2gmi by Molmil
Mms2/Ubc13~Ubiquitin
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 13, Ubiquitin-conjugating enzyme variant MMS2
著者Wolberger, C, Eddins, M.J, Carlile, C.M, Gomez, K.G, Pickart, C.M.
登録日2006-04-06
公開日2006-09-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation.
Nat.Struct.Mol.Biol., 13, 2006
3D4B
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BU of 3d4b by Molmil
Crystal structure of Sir2Tm in complex with Acetyl p53 peptide and DADMe-NAD+
分子名称: 5'-O-[(R)-{[(R)-{[(3R,4R)-1-(3-carbamoylbenzyl)-4-hydroxypyrrolidin-3-yl]methoxy}(hydroxy)phosphoryl]methyl}(hydroxy)phosphoryl]adenosine, Acetyl P53 peptide, NAD-dependent deacetylase, ...
著者Hawse, W.F, Hoff, K.G, Fatkins, D, Daines, A, Zubkova, O.V, Schramm, V.L, Zheng, W, Wolberger, C.
登録日2008-05-14
公開日2008-09-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into intermediate steps in the Sir2 deacetylation reaction.
Structure, 16, 2008
4FK5
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BU of 4fk5 by Molmil
Structure of the SAGA Ubp8(S144N)/Sgf11/Sus1/Sgf73 DUB module
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Protein SUS1, ...
著者Samara, N.L, Ringel, A.E, Wolberger, C.
登録日2012-06-12
公開日2012-07-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.032 Å)
主引用文献A Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and Activity.
Structure, 20, 2012
4FJC
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BU of 4fjc by Molmil
Structure of the SAGA Ubp8/Sgf11(1-72, Delta-ZnF)/Sus1/Sgf73 DUB module
分子名称: GLYCEROL, Protein SUS1, SAGA-associated factor 11, ...
著者Samara, N.L, Ringel, A.E, Wolberger, C.
登録日2012-06-11
公開日2012-07-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.826 Å)
主引用文献A Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and Activity.
Structure, 20, 2012
7UD5
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BU of 7ud5 by Molmil
Complex between MLL1-WRAD and an H2B-ubiquitinated nucleosome
分子名称: 601 DNA (146-MER), Histone H2A, Histone H2B 1.1, ...
著者Niklas, H.A, Rahman, S, Worden, E.J, Wolberger, C.
登録日2022-03-18
公開日2022-09-21
最終更新日2022-10-05
実験手法ELECTRON MICROSCOPY (4.25 Å)
主引用文献Multistate structures of the MLL1-WRAD complex bound to H2B-ubiquitinated nucleosome.
Proc.Natl.Acad.Sci.USA, 119, 2022
8G6H
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BU of 8g6h by Molmil
H2BK120ub+H3K79me2-modified nucleosome ubiquitin position 6
分子名称: 601 DNA (185-MER), Histone H2A, Histone H2B 1.1, ...
著者Hicks, C.W, Wolberger, C.
登録日2023-02-15
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Ubiquitinated H2B as gatekeeper of the nucleosome acidic patch
To Be Published
4TWI
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BU of 4twi by Molmil
The structure of Sir2Af1 bound to a succinylated histone peptide
分子名称: GLYCEROL, NAD-dependent protein deacylase 1, Succinylated H4 Peptide (aa8-20), ...
著者Ringel, A.E, Roman, C, Wolberger, C.
登録日2014-06-30
公開日2014-12-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Alternate deacylating specificities of the archaeal sirtuins Sir2Af1 and Sir2Af2.
Protein Sci., 23, 2014
4TWJ
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BU of 4twj by Molmil
The structure of Sir2Af2 bound to a myristoylated histone peptide
分子名称: ACETATE ION, GLYCEROL, Histone H4 peptide, ...
著者Ringel, A.E, Roman, C, Wolberger, C.
登録日2014-06-30
公開日2014-12-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Alternate deacylating specificities of the archaeal sirtuins Sir2Af1 and Sir2Af2.
Protein Sci., 23, 2014
8DU4
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BU of 8du4 by Molmil
Complex between RbBP5-WDR5 and an H2B-ubiquitinated nucleosome
分子名称: 601 DNA (146-MER), Histone H2A, Histone H2B 1.1, ...
著者Niklas, H.A, Rahman, S, Worden, E.J, Wolberger, C.
登録日2022-07-26
公開日2022-09-21
最終更新日2022-10-05
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Multistate structures of the MLL1-WRAD complex bound to H2B-ubiquitinated nucleosome.
Proc.Natl.Acad.Sci.USA, 119, 2022
1AKH
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BU of 1akh by Molmil
MAT A1/ALPHA2/DNA TERNARY COMPLEX
分子名称: DNA (5'-D(*TP*AP*CP*AP*TP*GP*TP*AP*AP*AP*AP*AP*TP*TP*TP*AP*C P*AP*TP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*GP*AP*TP*GP*TP*AP*AP*AP*TP*TP*TP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MATING-TYPE PROTEIN A-1), ...
著者Li, T, Jin, Y, Vershon, A.K, Wolberger, C.
登録日1997-05-19
公開日1998-05-20
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the MATa1/MATalpha2 homeodomain heterodimer in complex with DNA containing an A-tract.
Nucleic Acids Res., 26, 1998
6VEN
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BU of 6ven by Molmil
Yeast COMPASS in complex with a ubiquitinated nucleosome
分子名称: 601 DNA (146-MER), COMPASS component BRE2, COMPASS component SDC1, ...
著者Worden, E.J, Wolberger, C.
登録日2020-01-02
公開日2020-01-15
最終更新日2020-01-22
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Structural basis for COMPASS recognition of an H2B-ubiquitinated nucleosome.
Elife, 9, 2020
1MH3
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BU of 1mh3 by Molmil
maltose binding-a1 homeodomain protein chimera, crystal form I
分子名称: maltose binding-a1 homeodomain protein chimera
著者Ke, A, Wolberger, C.
登録日2002-08-19
公開日2002-09-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Insights into binding cooperativity of MATa1/MATalpha2 from the crystal structure of a MATa1 homeodomain-maltose binding protein chimera
Protein Sci., 12, 2003
1MH4
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BU of 1mh4 by Molmil
maltose binding-a1 homeodomain protein chimera, crystal form II
分子名称: maltose binding-a1 homeodomain protein chimera
著者Ke, A, Wolberger, C.
登録日2002-08-19
公開日2002-09-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Insights into binding cooperativity of MATa1/MATalpha2 from the crystal structure of a MATa1 homeodomain-maltose binding protein chimera
Protein Sci., 12, 2003
1MDM
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BU of 1mdm by Molmil
INHIBITED FRAGMENT OF ETS-1 AND PAIRED DOMAIN OF PAX5 BOUND TO DNA
分子名称: C-ETS-1 PROTEIN, PAIRED BOX PROTEIN PAX-5, PAX5/ETS BINDING SITE ON THE MB-1 PROMOTER
著者Garvie, C.W, Pufall, M.A, Graves, B.J, Wolberger, C.
登録日2002-08-07
公開日2002-12-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献STRUCTURAL ANALYSIS OF THE AUTOINHIBITION OF ETS-1 AND ITS ROLE IN PROTEIN PARTNERSHIPS
J.Biol.Chem., 277, 2002
1MD0
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BU of 1md0 by Molmil
CRYSTAL STRUCTURE OF AN INHIBITED FRAGMENT OF Ets-1
分子名称: C-ets-1 protein
著者Garvie, C.W, Pufall, M.A, Graves, B.J, Wolberger, C.
登録日2002-08-06
公開日2002-12-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Analysis of the Autoinhibition of Ets-1 and Its Role in Protein Partnerships
J.Biol.Chem., 277, 2002
6AQR
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BU of 6aqr by Molmil
SAGA DUB module Ubp8(C146A)/Sgf11/Sus1/Sgf73 bound to monoubiquitin
分子名称: Polyubiquitin-C, SAGA-associated factor 11, SAGA-associated factor 73, ...
著者Morrow, M.E, Morgan, M.T, Wolberger, C.
登録日2017-08-21
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Active site alanine mutations convert deubiquitinases into high-affinity ubiquitin-binding proteins.
EMBO Rep., 19, 2018
4LDT
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BU of 4ldt by Molmil
The structure of h/ceOTUB1-ubiquitin aldehyde-UBCH5B~Ub
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, Ubiquitin, ...
著者Wiener, R, DiBello, A.T, Lombardi, P.M, Guzzo, C.M, Zhang, X, Matunis, M.J, Wolberger, C.
登録日2013-06-25
公開日2013-08-14
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1.
Nat.Struct.Mol.Biol., 20, 2013
4ZUX
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BU of 4zux by Molmil
SAGA DUB module Ubp8/Sgf11/Sus1/Sgf73 bound to ubiqitinated nucleosome
分子名称: DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Morgan, M, Wolberger, C.
登録日2015-05-17
公開日2016-02-24
最終更新日2016-03-09
実験手法X-RAY DIFFRACTION (3.82 Å)
主引用文献Structural basis for histone H2B deubiquitination by the SAGA DUB module.
Science, 351, 2016
1ERJ
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BU of 1erj by Molmil
CRYSTAL STRUCTURE OF THE C-TERMINAL WD40 DOMAIN OF TUP1
分子名称: TRANSCRIPTIONAL REPRESSOR TUP1
著者Sprague, E.R, Redd, M.J, Johnson, A.D, Wolberger, C.
登録日2000-04-06
公開日2000-07-26
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the C-terminal domain of Tup1, a corepressor of transcription in yeast.
EMBO J., 19, 2000

 

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