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PDB: 359 件

3TLH
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STRUCTURAL STUDIES OF HIV AND FIV PROTEASES COMPLEXED WITHAN EFFICIENT INHIBITOR OF FIV PR
分子名称: PROTEIN (PROTEASE), benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate
著者Li, M, Lee, T, Morris, G, Laco, G, Wong, C, Olson, A, Elder, J, Wlodawer, A, Gustchina, A.
登録日1998-12-03
公開日1998-12-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease
Proteins, 38, 2000
5C9B
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Crystal structure of a retropepsin-like aspartic protease from Rickettsia conorii
分子名称: ApRick protease
著者Li, M, Gustchina, A, Cruz, R, Simoes, M, Curto, P, Martinez, J, Faro, C, Simoes, I, Wlodawer, A.
登録日2015-06-26
公開日2015-10-14
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of RC1339/APRc from Rickettsia conorii, a retropepsin-like aspartic protease.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
5C9D
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Crystal structure of a retropepsin-like aspartic protease from Rickettsia conorii
分子名称: ApRick protease, SODIUM ION
著者Li, M, Gustchina, A, Cruz, R, Simoes, M, Curto, P, Martinez, J, Faro, C, Simoes, I, Wlodawer, A.
登録日2015-06-26
公開日2015-10-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structure of RC1339/APRc from Rickettsia conorii, a retropepsin-like aspartic protease
Acta Crystallogr.,Sect.D, 71, 2015
7R6A
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Crystal structure of mutant L124D/R125A/C273S of L-Asparaginase I from Yersinia pestis
分子名称: FORMIC ACID, L-asparaginase I
著者Strzelczyk, P, Wlodawer, A, Lubkowski, J.
登録日2021-06-22
公開日2022-07-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献The dimeric form of bacterial l-asparaginase YpAI is fully active.
Febs J., 290, 2023
7R69
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Crystal structure of mutant R43D/C273S of L-Asparaginase I from Yersinia pestis
分子名称: 1,2-ETHANEDIOL, L-asparaginase I
著者Strzelczyk, P, Wlodawer, A, Lubkowski, J.
登録日2021-06-22
公開日2022-07-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The dimeric form of bacterial l-asparaginase YpAI is fully active.
Febs J., 290, 2023
7R6B
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Crystal structure of mutant R43D/L124D/R125A/C273S of L-Asparaginase I from Yersinia pestis
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, L-asparaginase I
著者Strzelczyk, P, Wlodawer, A, Lubkowski, J.
登録日2021-06-22
公開日2022-07-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献The dimeric form of bacterial l-asparaginase YpAI is fully active.
Febs J., 290, 2023
5C9F
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Crystal structure of a retropepsin-like aspartic protease from Rickettsia conorii
分子名称: ApRick protease, CHLORIDE ION, SODIUM ION
著者Li, M, Gustchina, A, Cruz, R, Simoes, M, Curto, P, Martinez, J, Faro, C, Simoes, I, Wlodawer, A.
登録日2015-06-26
公開日2015-10-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of RC1339/APRc from Rickettsia conorii, a retropepsin-like aspartic protease.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
8UOR
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Structure of atypical asparaginase from Rhodospirillum rubrum (mutant K19E)
分子名称: 1,2-ETHANEDIOL, Asparaginase, CHLORIDE ION
著者Lubkowski, J, Wlodawer, A, Zhang, D.
登録日2023-10-20
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases.
Protein Sci., 33, 2024
8UP9
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Structure of atypical asparaginase from Rhodospirillum rubrum (mutant K19Q)
分子名称: 1,2-ETHANEDIOL, Asparaginase, CHLORIDE ION, ...
著者Lubkowski, J, Wlodawer, A, Zhang, D.
登録日2023-10-21
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases.
Protein Sci., 33, 2024
8UPC
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Structure of atypical asparaginase from Rhodospirillum rubrum (mutant K158M)
分子名称: Asparaginase, CHLORIDE ION, GLYCEROL
著者Lubkowski, J, Wlodawer, A, Zhang, D.
登録日2023-10-22
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases.
Protein Sci., 33, 2024
8UP6
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Structure of atypical asparaginase from Rhodospirillum rubrum (mutant K19A) in complex with L-Asp
分子名称: ASPARTIC ACID, Asparaginase, TETRAETHYLENE GLYCOL
著者Lubkowski, J, Wlodawer, A, Zhang, D.
登録日2023-10-21
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases.
Protein Sci., 33, 2024
8UOU
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Structure of atypical asparaginase from Rhodospirillum rubrum in complex with L-Asp
分子名称: ASPARTIC ACID, Asparaginase, CHLORIDE ION
著者Lubkowski, J, Wlodawer, A, Zhang, D.
登録日2023-10-20
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases.
Protein Sci., 33, 2024
8UOO
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Structure of atypical asparaginase from Rhodospirillum rubrum
分子名称: Asparaginase, CHLORIDE ION, GLYCEROL
著者Lubkowski, J, Wlodawer, A, Zhang, D.
登録日2023-10-20
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases.
Protein Sci., 33, 2024
8UP7
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BU of 8up7 by Molmil
Structure of atypical asparaginase from Rhodospirillum rubrum (mutant K19A)
分子名称: Asparaginase, CHLORIDE ION
著者Lubkowski, J, Wlodawer, A, Zhang, D.
登録日2023-10-21
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases.
Protein Sci., 33, 2024
8UP8
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Structure of atypical asparaginase from Rhodospirillum rubrum (mutant Y21F, complex with L-Asp)
分子名称: ASPARTIC ACID, Asparaginase, CHLORIDE ION, ...
著者Lubkowski, J, Wlodawer, A, Zhang, D.
登録日2023-10-21
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases.
Protein Sci., 33, 2024
8UOW
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Structure of atypical asparaginase from Rhodospirillum rubrum (mutant Y21A)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Asparaginase
著者Lubkowski, J, Wlodawer, A, Zhang, D.
登録日2023-10-20
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases.
Protein Sci., 33, 2024
8UP3
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Structure of atypical asparaginase from Rhodospirillum rubrum (mutant Y21F)
分子名称: 1,2-ETHANEDIOL, ASPARTIC ACID, Asparaginase, ...
著者Lubkowski, J, Wlodawer, A, Zhang, D.
登録日2023-10-20
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases.
Protein Sci., 33, 2024
4O1S
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Crystal structure of TvoVMA intein
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION, ...
著者Aranko, A.S, Oeemig, J.S, Zhou, D, Kajander, T, Wlodawer, A, Iwai, H.
登録日2013-12-16
公開日2014-03-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7008 Å)
主引用文献Structure-based engineering and comparison of novel split inteins for protein ligation.
Mol Biosyst, 10, 2014
4O1R
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Crystal structure of NpuDnaB intein
分子名称: CHLORIDE ION, GLYCEROL, Replicative DNA helicase, ...
著者Aranko, A.S, Oeemig, J.S, Zhou, D, Kajander, T, Wlodawer, A, Iwai, H.
登録日2013-12-16
公開日2014-03-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure-based engineering and comparison of novel split inteins for protein ligation.
Mol Biosyst, 10, 2014
1AGX
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REFINED CRYSTAL STRUCTURE OF ACINETOBACTER GLUTAMINASIFICANS GLUTAMINASE-ASPARAGINASE
分子名称: GLUTAMINASE-ASPARAGINASE
著者Lubkowski, J, Wlodawer, A, Housset, D, Weber, I.T, Ammon, H.L, Murphy, K.C, Swain, A.L.
登録日1994-07-13
公開日1994-12-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Refined crystal structure of Acinetobacter glutaminasificans glutaminase-asparaginase.
Acta Crystallogr.,Sect.D, 50, 1994
6WZ8
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Complex of Pseudomonas 7A Glutaminase-Asparaginase with Citrate Anion at pH 5.5. Covalent Acyl-Enzyme Intermediate
分子名称: CITRIC ACID, Glutaminase-asparaginase
著者Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J.
登録日2020-05-13
公開日2020-10-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
Sci Rep, 10, 2020
6WYY
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Crystal structure of Pseudomonas 7A Glutaminase-Asparaginase in complex with L-Glu at pH 6.5
分子名称: 1,2-ETHANEDIOL, GLUTAMIC ACID, GLYCEROL, ...
著者Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J.
登録日2020-05-13
公開日2020-10-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
Sci Rep, 10, 2020
6X5M
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Crystal structure of a stabilized PAN ENE bimolecular triplex with a GC-clamped polyA tail, in complex with Fab-BL-3,6.
分子名称: Heavy chain Fab Bl-3 6, Light chain Fab BL-3 6, SULFATE ION, ...
著者Swain, M, Li, M, Wlodawer, A, Le Grice, S.F.J.
登録日2020-05-26
公開日2020-06-24
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Dynamic bulge nucleotides in the KSHV PAN ENE triple helix provide a unique binding platform for small molecule ligands.
Nucleic Acids Res., 49, 2021
6WYZ
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Crystal structure of Pseudomonas 7A Glutaminase-Asparaginase (mutant K173M) in complex with D-Glu at pH 5.5
分子名称: D-GLUTAMIC ACID, Glutaminase-asparaginase
著者Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J.
登録日2020-05-13
公開日2020-10-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
Sci Rep, 10, 2020
6WZ4
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Complex of mutant (K173M) of Pseudomonas 7A Glutaminase-Asparaginase with L-Asp at pH 6. Covalent acyl-enzyme intermediate
分子名称: ASPARTIC ACID, Glutaminase-asparaginase
著者Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J.
登録日2020-05-13
公開日2020-10-14
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
Sci Rep, 10, 2020

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