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PDB: 358 件

2HYQ
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Crystal structure of a complex of griffithsin with 6alpha-mannobiose
分子名称: Griffithsin, SULFATE ION, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose
著者Ziolkowska, N.E, Wlodawer, A.
登録日2006-08-07
公開日2007-04-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin.
Proteins, 67, 2007
6WYW
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BU of 6wyw by Molmil
Crystal structure of Pseudomonas 7A Glutaminase-Asparaginase in complex with L-Asp at pH 4.5
分子名称: ASPARTIC ACID, Glutaminase-asparaginase
著者Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J.
登録日2020-05-13
公開日2020-10-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
Sci Rep, 10, 2020
6WYX
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Crystal structure of Pseudomonas 7A Glutaminase-Asparaginase in complex with L-Asp at pH 5.0
分子名称: ASPARTIC ACID, GLYCEROL, Glutaminase-asparaginase
著者Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J.
登録日2020-05-13
公開日2020-10-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
Sci Rep, 10, 2020
2NUO
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Crystal structure of a complex of griffithsin with glucose
分子名称: 1,2-ETHANEDIOL, Griffithsin, SULFATE ION, ...
著者Ziolkowska, N.E, Wlodawer, A.
登録日2006-11-09
公開日2007-08-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystallographic studies of the complexes of antiviral protein griffithsin with glucose and N-acetylglucosamine.
Protein Sci., 16, 2007
1ODY
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BU of 1ody by Molmil
HIV-1 PROTEASE COMPLEXED WITH AN INHIBITOR LP-130
分子名称: 4-[2-(2-ACETYLAMINO-3-NAPHTALEN-1-YL-PROPIONYLAMINO)-4-METHYL-PENTANOYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL)-PROPYL]-AMIDE, HIV-1 PROTEASE
著者Kervinen, J, Lubkowski, J, Zdanov, A, Wlodawer, A, Gustchina, A.
登録日1998-07-13
公開日1999-02-16
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Toward a universal inhibitor of retroviral proteases: comparative analysis of the interactions of LP-130 complexed with proteases from HIV-1, FIV, and EIAV.
Protein Sci., 7, 1998
6WZ8
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BU of 6wz8 by Molmil
Complex of Pseudomonas 7A Glutaminase-Asparaginase with Citrate Anion at pH 5.5. Covalent Acyl-Enzyme Intermediate
分子名称: CITRIC ACID, Glutaminase-asparaginase
著者Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J.
登録日2020-05-13
公開日2020-10-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
Sci Rep, 10, 2020
6WZ4
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Complex of mutant (K173M) of Pseudomonas 7A Glutaminase-Asparaginase with L-Asp at pH 6. Covalent acyl-enzyme intermediate
分子名称: ASPARTIC ACID, Glutaminase-asparaginase
著者Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J.
登録日2020-05-13
公開日2020-10-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
Sci Rep, 10, 2020
1QDM
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CRYSTAL STRUCTURE OF PROPHYTEPSIN, A ZYMOGEN OF A BARLEY VACUOLAR ASPARTIC PROTEINASE.
分子名称: PROPHYTEPSIN
著者Kervinen, J, Tobin, G.J, Costa, J, Waugh, D.S, Wlodawer, A, Zdanov, A.
登録日1999-05-19
公開日1999-07-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of plant aspartic proteinase prophytepsin: inactivation and vacuolar targeting.
EMBO J., 18, 1999
6WYZ
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Crystal structure of Pseudomonas 7A Glutaminase-Asparaginase (mutant K173M) in complex with D-Glu at pH 5.5
分子名称: D-GLUTAMIC ACID, Glutaminase-asparaginase
著者Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J.
登録日2020-05-13
公開日2020-10-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
Sci Rep, 10, 2020
2QSK
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Atomic-resolution crystal structure of the Recombinant form of Scytovirin
分子名称: CHLORIDE ION, GLYCEROL, scytovirin
著者Moulaei, T, Botos, I, Ziolkowska, N.E, Dauter, Z, Wlodawer, A.
登録日2007-07-31
公開日2007-11-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Atomic-resolution crystal structure of the antiviral lectin scytovirin.
Protein Sci., 16, 2007
2GTY
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Crystal structure of unliganded griffithsin
分子名称: 1,2-ETHANEDIOL, Griffithsin, SULFATE ION
著者Ziolkowska, N.E, Wlodawer, A.
登録日2006-04-28
公開日2006-08-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Domain-swapped structure of the potent antiviral protein griffithsin and its mode of carbohydrate binding.
Structure, 14, 2006
3LKY
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Monomeric Griffithsin with a Single Gly-Ser Insertion
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Griffithsin, ...
著者Moulaei, T, Wlodawer, A.
登録日2010-01-28
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.11 Å)
主引用文献Monomerization of viral entry inhibitor griffithsin elucidates the relationship between multivalent binding to carbohydrates and anti-HIV activity.
Structure, 18, 2010
3LL2
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Monomeric Griffithsin in Complex with a High-Mannose Branched Carbohydrate
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Griffithsin, ...
著者Moulaei, T, Wlodawer, A.
登録日2010-01-28
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (0.97 Å)
主引用文献Monomerization of viral entry inhibitor griffithsin elucidates the relationship between multivalent binding to carbohydrates and anti-HIV activity.
Structure, 18, 2010
2GUC
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Crystal structure of a complex of griffithsin with mannose at 1.78 A resolution.
分子名称: 1,2-ETHANEDIOL, SULFATE ION, alpha-D-mannopyranose, ...
著者Ziolkowska, N.E, Wlodawer, A.
登録日2006-04-29
公開日2006-08-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Domain-swapped structure of the potent antiviral protein griffithsin and its mode of carbohydrate binding.
Structure, 14, 2006
3LL0
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Monomeric Griffithsin with two Gly-Ser Insertions
分子名称: GLYCEROL, Griffithsin, SULFATE ION
著者Moulaei, T, Wlodawer, A.
登録日2010-01-28
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Monomerization of viral entry inhibitor griffithsin elucidates the relationship between multivalent binding to carbohydrates and anti-HIV activity.
Structure, 18, 2010
3QVI
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BU of 3qvi by Molmil
Crystal structure of KNI-10395 bound histo-aspartic protease (HAP) from Plasmodium falciparum
分子名称: (4R)-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-3-[(2S,3S)-2-hydroxy-3-{[S-methyl-N-(phenylacetyl)-L-cysteinyl]amino}-4-phenylbutanoyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide, 1,2-ETHANEDIOL, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, ...
著者Bhaumik, P, Gustchina, A, Wlodawer, A.
登録日2011-02-25
公開日2011-10-12
最終更新日2013-09-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into the activation and inhibition of histo-aspartic protease from Plasmodium falciparum.
Biochemistry, 50, 2011
1O7J
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BU of 1o7j by Molmil
Atomic resolution structure of Erwinia chrysanthemi L-asparaginase
分子名称: 1,2-ETHANEDIOL, GLYCEROL, L-ASPARAGINASE, ...
著者Lubkowski, J, Dauter, M, Aghaiypour, K, Wlodawer, A, Dauter, Z.
登録日2002-11-07
公開日2002-12-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Atomic Resolution Structure of Erwinia Chrysanthemi L-Asparaginase
Acta Crystallogr.,Sect.D, 59, 2003
3SM1
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The crystal structure of XMRV protease complexed with pepstatin A
分子名称: FORMIC ACID, Pepstatin A, gag-pro-pol polyprotein
著者Li, M, Gustchina, A, Wlodawer, A.
登録日2011-06-27
公開日2011-10-12
最終更新日2014-11-12
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and biochemical characterization of the inhibitor complexes of xenotropic murine leukemia virus-related virus protease.
Febs J., 278, 2011
2NU5
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Crystal structure of a complex of griffithsin cocrystallized with N-acetylglucosamine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, griffithsin
著者Ziolkowska, N.E, Wlodawer, A.
登録日2006-11-08
公開日2007-08-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.564 Å)
主引用文献Crystallographic studies of the complexes of antiviral protein griffithsin with glucose and N-acetylglucosamine
Protein Sci., 16, 2007
1L6Y
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BU of 1l6y by Molmil
Crystal Structure of Porphobilinogen Synthase Complexed with the Inhibitor 4-Oxosebacic Acid
分子名称: 4-OXODECANEDIOIC ACID, GLYCEROL, MAGNESIUM ION, ...
著者Jaffe, E.K, Kervinen, J, Martins, J, Stauffer, F, Neier, R, Wlodawer, A, Zdanov, A.
登録日2002-03-14
公開日2002-04-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Species-Specific Inhibition of Porphobilinogen Synthase by 4-Oxosebacic Acid
J.Biol.Chem., 277, 2002
2GUD
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Crystal structure of a complex of griffithsin with mannose at 0.94 A resolution
分子名称: 1,2-ETHANEDIOL, SULFATE ION, alpha-D-mannopyranose, ...
著者Ziolkowska, N.E, Wlodawer, A.
登録日2006-04-29
公開日2006-08-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (0.94 Å)
主引用文献Domain-swapped structure of the potent antiviral protein griffithsin and its mode of carbohydrate binding.
Structure, 14, 2006
2GUE
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Crystal structure of a complex of griffithsin with N-acetylglucosamine
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ...
著者Ziolkowska, N.E, Wlodawer, A.
登録日2006-04-29
公開日2006-08-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Domain-swapped structure of the potent antiviral protein griffithsin and its mode of carbohydrate binding.
Structure, 14, 2006
1QZM
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alpha-domain of ATPase
分子名称: ATP-dependent protease La
著者Botos, I, Melnikov, E.E, Cherry, S, Khalatova, A.G, Rasulova, F.S, Tropea, J.E, Maurizi, M.R, Rotanova, T.V, Gustchina, A, Wlodawer, A.
登録日2003-09-17
公開日2004-05-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the AAA+ alpha domain of E. coli Lon protease at 1.9A resolution.
J.Struct.Biol., 146
2NSZ
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1.15 Angstrom Crystal Structure of the MA3 domain of Pdcd4
分子名称: GLYCEROL, Programmed cell death protein 4, SULFATE ION
著者LaRonde-LeBlanc, N, Wlodawer, A.
登録日2006-11-06
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structural basis for inhibition of translation by the tumor suppressor Pdcd4.
Mol.Cell.Biol., 27, 2007
1QMH
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Crystal structure of RNA 3'-terminal phosphate cyclase, an ubiquitous enzyme with unusual topology
分子名称: 1-HYDROXYSULFANYL-4-MERCAPTO-BUTANE-2,3-DIOL, CITRIC ACID, RNA 3'-TERMINAL PHOSPHATE CYCLASE
著者Palm, G.J, Billy, E, Filipowicz, W, Wlodawer, A.
登録日1999-09-28
公開日2000-01-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of RNA 3'-Terminal Phosphate Cyclase, a Ubiquitous Enzyme with Unusual Topology
Structure, 8, 2000

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