4NQI
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![BU of 4nqi by Molmil](/molmil-images/mine/4nqi) | Structure of the N-terminal I-BAR domain (1-259) of D.Discoideum IBARa | 分子名称: | ACETATE ION, DI(HYDROXYETHYL)ETHER, SH3 domain-containing protein | 著者 | Witte, G, Faix, J, Runge-Wollmann, P. | 登録日 | 2013-11-25 | 公開日 | 2014-02-05 | 最終更新日 | 2014-04-02 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | The inverse BAR domain protein IBARa drives membrane remodeling to control osmoregulation, phagocytosis and cytokinesis. J.Cell.Sci., 127, 2014
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3C23
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![BU of 3c23 by Molmil](/molmil-images/mine/3c23) | Structure of a bacterial DNA damage sensor protein with non-reactive Ligand | 分子名称: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, DNA integrity scanning protein disA | 著者 | Witte, G, Hartung, S, Buttner, K, Hopfner, K.P. | 登録日 | 2008-01-24 | 公開日 | 2008-05-06 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Biochemistry of a Bacterial Checkpoint Protein Reveals Diadenylate Cyclase Activity Regulated by DNA Recombination Intermediates Mol.Cell, 30, 2008
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3C1Z
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3C1Y
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![BU of 3c1y by Molmil](/molmil-images/mine/3c1y) | Structure of bacterial DNA damage sensor protein with co-purified and co-crystallized ligand | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, DNA integrity scanning protein disA | 著者 | Witte, G, Hartung, S, Buttner, K, Hopfner, K.P. | 登録日 | 2008-01-24 | 公開日 | 2008-05-06 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Biochemistry of a Bacterial Checkpoint Protein Reveals Diadenylate Cyclase Activity Regulated by DNA Recombination Intermediates Mol.Cell, 30, 2008
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3C21
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![BU of 3c21 by Molmil](/molmil-images/mine/3c21) | Structure of a bacterial DNA damage sensor protein with reaction product | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, DNA integrity scanning protein disA | 著者 | Witte, G, Hartung, S, Buttner, K, Hopfner, K.P. | 登録日 | 2008-01-24 | 公開日 | 2008-05-06 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Biochemistry of a Bacterial Checkpoint Protein Reveals Diadenylate Cyclase Activity Regulated by DNA Recombination Intermediates Mol.Cell, 30, 2008
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5O4Z
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![BU of 5o4z by Molmil](/molmil-images/mine/5o4z) | Structure of the inactive T.maritima PDE (TM1595) D80N D154N mutant with substrate 5'-pApA | 分子名称: | ADENOSINE-5'-MONOPHOSPHATE, CHLORIDE ION, DHH/DHHA1-type phosphodiesterase TM1595, ... | 著者 | Witte, G, Drexler, D, Mueller, M. | 登録日 | 2017-05-31 | 公開日 | 2017-10-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural and Biophysical Analysis of the Soluble DHH/DHHA1-Type Phosphodiesterase TM1595 from Thermotoga maritima. Structure, 25, 2017
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5O7F
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![BU of 5o7f by Molmil](/molmil-images/mine/5o7f) | Structure of the inactive T.maritima PDE (TM1595) D80N D154N mutant with GMP and Mn2+ | 分子名称: | 1,2-ETHANEDIOL, GUANOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, ... | 著者 | Witte, G, Drexler, D, Mueller, M. | 登録日 | 2017-06-08 | 公開日 | 2017-10-25 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and Biophysical Analysis of the Soluble DHH/DHHA1-Type Phosphodiesterase TM1595 from Thermotoga maritima. Structure, 25, 2017
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5O25
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![BU of 5o25 by Molmil](/molmil-images/mine/5o25) | Structure of wildtype T.maritima PDE (TM1595) in ligand-free state | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ... | 著者 | Witte, G, Drexler, D, Mueller, M. | 登録日 | 2017-05-19 | 公開日 | 2017-10-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural and Biophysical Analysis of the Soluble DHH/DHHA1-Type Phosphodiesterase TM1595 from Thermotoga maritima. Structure, 25, 2017
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5O70
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5O1U
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![BU of 5o1u by Molmil](/molmil-images/mine/5o1u) | Structure of wildtype T.maritima PDE (TM1595) with AMP and Mn2+ | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ... | 著者 | Witte, G, Drexler, D, Mueller, M. | 登録日 | 2017-05-19 | 公開日 | 2017-10-25 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and Biophysical Analysis of the Soluble DHH/DHHA1-Type Phosphodiesterase TM1595 from Thermotoga maritima. Structure, 25, 2017
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5O58
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![BU of 5o58 by Molmil](/molmil-images/mine/5o58) | Structure of the inactive T.maritima PDE (TM1595) D80N D154N mutant with substrate 5'-pApG | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, ISOPROPYL ALCOHOL, ... | 著者 | Witte, G, Drexler, D, Mueller, M. | 登録日 | 2017-06-01 | 公開日 | 2017-10-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural and Biophysical Analysis of the Soluble DHH/DHHA1-Type Phosphodiesterase TM1595 from Thermotoga maritima. Structure, 25, 2017
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4I1S
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2IHE
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![BU of 2ihe by Molmil](/molmil-images/mine/2ihe) | Crystal structure of wild-type single-stranded DNA binding protein from Thermus aquaticus | 分子名称: | Single-stranded DNA-binding protein | 著者 | Fedorov, R, Witte, G, Urbanke, C, Manstein, D.J, Curth, U. | 登録日 | 2006-09-26 | 公開日 | 2007-01-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | 3D structure of Thermus aquaticus single-stranded DNA-binding protein gives insight into the functioning of SSB proteins. Nucleic Acids Res., 34, 2006
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7B5W
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7B5U
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![BU of 7b5u by Molmil](/molmil-images/mine/7b5u) | RCK_C domain dimer of S.agalactiae BusR in complex with c-di-AMP | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, GntR family transcriptional regulator | 著者 | Bandera, A.M, Witte, G. | 登録日 | 2020-12-07 | 公開日 | 2021-08-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | BusR senses bipartite DNA binding motifs by a unique molecular ruler architecture. Nucleic Acids Res., 49, 2021
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7B5Y
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![BU of 7b5y by Molmil](/molmil-images/mine/7b5y) | S. agalactiae BusR in complex with its busAB-promotor DNA | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, BusR binding site in the busAB promotor. strand1, BusR binding site in the busAB promotor. strand2, ... | 著者 | Bandera, A.M, Witte, G. | 登録日 | 2020-12-07 | 公開日 | 2021-08-11 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | 主引用文献 | BusR senses bipartite DNA binding motifs by a unique molecular ruler architecture. Nucleic Acids Res., 49, 2021
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7B5T
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7A08
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![BU of 7a08 by Molmil](/molmil-images/mine/7a08) | CryoEM Structure of cGAS Nucleosome complex | 分子名称: | Cyclic GMP-AMP synthase, Histone H2A type 1-C, Histone H2B type 1-C/E/F/G/I, ... | 著者 | Michalski, S, de Oliveira Mann, C.C, Witte, G, Bartho, J, Lammens, K, Hopfner, K.P. | 登録日 | 2020-08-07 | 公開日 | 2020-09-23 | 最終更新日 | 2021-02-10 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | Structural basis for sequestration and autoinhibition of cGAS by chromatin. Nature, 587, 2020
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7OZ3
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![BU of 7oz3 by Molmil](/molmil-images/mine/7oz3) | S. agalactiae BusR in complex with its busA-promotor DNA | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, GntR family transcriptional regulator, pBusA_for, ... | 著者 | Bandera, A.M, Witte, G. | 登録日 | 2021-06-25 | 公開日 | 2021-08-11 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (4.46 Å) | 主引用文献 | BusR senses bipartite DNA binding motifs by a unique molecular ruler architecture. Nucleic Acids Res., 49, 2021
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4WK1
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![BU of 4wk1 by Molmil](/molmil-images/mine/4wk1) | Crystal structure of Staphylococcus aureus PstA in complex with c-di-AMP | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, CALCIUM ION, PstA | 著者 | Mueller, M, Hopfner, K.-P, Witte, G. | 登録日 | 2014-10-01 | 公開日 | 2014-11-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | c-di-AMP recognition by Staphylococcus aureus PstA. Febs Lett., 589, 2015
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4WK3
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5EOM
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![BU of 5eom by Molmil](/molmil-images/mine/5eom) | Structure of full-length human MAB21L1 with bound CTP | 分子名称: | CITRIC ACID, CYTIDINE-5'-TRIPHOSPHATE, Protein mab-21-like 1, ... | 著者 | de Oliveira Mann, C.C, Witte, G, Hopfner, K.-P. | 登録日 | 2015-11-10 | 公開日 | 2016-06-01 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structural and biochemical characterization of the cell fate determining nucleotidyltransferase fold protein MAB21L1. Sci Rep, 6, 2016
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5EOG
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3TJ1
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![BU of 3tj1 by Molmil](/molmil-images/mine/3tj1) | Crystal Structure of RNA Polymerase I Transcription Initiation Factor Rrn3 | 分子名称: | RNA polymerase I-specific transcription initiation factor RRN3 | 著者 | Blattner, C, Jennebach, S, Herzog, F, Mayer, A, Cheung, A.C.M, Witte, G, Lorenzen, K, Hopfner, K.-P, Heck, A.J.R, Aebersold, R, Cramer, P. | 登録日 | 2011-08-23 | 公開日 | 2011-09-28 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth. Genes Dev., 25, 2011
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4ON9
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![BU of 4on9 by Molmil](/molmil-images/mine/4on9) | DECH box helicase domain | 分子名称: | CHLORIDE ION, Probable ATP-dependent RNA helicase DDX58, SULFATE ION | 著者 | Deimling, T, Witte, G, Hopfner, K.P. | 登録日 | 2014-01-28 | 公開日 | 2014-07-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Crystal and solution structure of the human RIG-I SF2 domain Acta Crystallogr.,Sect.F, 70, 2014
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