3C21

Structure of a bacterial DNA damage sensor protein with reaction product

Summary for 3C21

• Entry DOI: 10.2210/pdb3c21/pdb
• Related: 3C1Y 3C1Z 3C23
• Descriptor: DNA integrity scanning protein disA, (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide (3 entities in total)
• Functional Keywords: dna damage, dna repair, dna-binding, dna binding protein
• Biological source: Thermotoga maritima
• Total number of polymer chains: 2
• Total formula weight: 86186.38

Authors

Witte, G.,Hartung, S.,Buttner, K.,Hopfner, K.P. (deposition date: 2008-01-24, release date: 2008-05-06, Last modification date: 2023-11-01)

• Primary citation: Witte, G.,Hartung, S.,Buttner, K.,Hopfner, K.P.; Structural Biochemistry of a Bacterial Checkpoint Protein Reveals Diadenylate Cyclase Activity Regulated by DNA Recombination Intermediates; Mol.Cell, 30:167-178, 2008; PubMed: 18439896; DOI: 10.1016/j.molcel.2008.02.020

Experimental method

X-RAY DIFFRACTION (2.7 Å)