6HY2
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5MPQ
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6FPN
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![BU of 6fpn by Molmil](/molmil-images/mine/6fpn) | Lytic transglycosylase in action | Descriptor: | Putative soluble lytic murein transglycosylase, SULFATE ION | Authors: | Williams, A.H, Hoauz, A, Boneca, I.G. | Deposit date: | 2018-02-11 | Release date: | 2018-03-14 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | A step-by-stepin crystalloguide to bond cleavage and 1,6-anhydro-sugar product synthesis by a peptidoglycan-degrading lytic transglycosylase. J. Biol. Chem., 293, 2018
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6QCM
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![BU of 6qcm by Molmil](/molmil-images/mine/6qcm) | Cryo em structure of the Listeria stressosome | Descriptor: | RsbR protein, RsbR protein,RsbR protein, RsbS protein | Authors: | Williams, A.H, Redzej, A, Waksman, G, Cossart, P. | Deposit date: | 2018-12-28 | Release date: | 2019-08-21 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.21 Å) | Cite: | The cryo-electron microscopy supramolecular structure of the bacterial stressosome unveils its mechanism of activation. Nat Commun, 10, 2019
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6H5F
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![BU of 6h5f by Molmil](/molmil-images/mine/6h5f) | LtgA disordered Helix | Descriptor: | Putative soluble lytic murein transglycosylase | Authors: | Williams, A.H. | Deposit date: | 2018-07-24 | Release date: | 2019-08-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Defective lytic transglycosylase disrupts cell morphogenesis by hindering cell wall de-O-acetylation inNeisseria meningitidis. Elife, 9, 2020
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2QIV
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2QIA
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2AQ9
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![BU of 2aq9 by Molmil](/molmil-images/mine/2aq9) | Structure of E. coli LpxA with a bound peptide that is competitive with acyl-ACP | Descriptor: | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... | Authors: | Williams, A.H, Immormino, R.M, Gewirth, D.T, Raetz, C.R. | Deposit date: | 2005-08-17 | Release date: | 2006-06-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial pentadecapeptide. Proc.Natl.Acad.Sci.Usa, 103, 2006
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5O29
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![BU of 5o29 by Molmil](/molmil-images/mine/5o29) | Lytic transglycosylase in action | Descriptor: | Transglycosylase | Authors: | Williams, A.H, Hoauz, A, Boneca, I.G. | Deposit date: | 2017-05-19 | Release date: | 2018-03-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.3785 Å) | Cite: | A step-by-stepin crystalloguide to bond cleavage and 1,6-anhydro-sugar product synthesis by a peptidoglycan-degrading lytic transglycosylase. J. Biol. Chem., 293, 2018
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5O2N
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![BU of 5o2n by Molmil](/molmil-images/mine/5o2n) | Lytic transglycosylase in action | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, CITRATE ANION, ... | Authors: | Williams, A.H, Hoauz, A, Boneca, I.G. | Deposit date: | 2017-05-22 | Release date: | 2018-03-14 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.513 Å) | Cite: | A step-by-stepin crystalloguide to bond cleavage and 1,6-anhydro-sugar product synthesis by a peptidoglycan-degrading lytic transglycosylase. J. Biol. Chem., 293, 2018
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5O24
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![BU of 5o24 by Molmil](/molmil-images/mine/5o24) | Lytic transglycosylase in action | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Transglycosylase | Authors: | Williams, A.H, Hoauz, A, Boneca, I.G. | Deposit date: | 2017-05-19 | Release date: | 2018-03-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.429 Å) | Cite: | A step-by-stepin crystalloguide to bond cleavage and 1,6-anhydro-sugar product synthesis by a peptidoglycan-degrading lytic transglycosylase. J. Biol. Chem., 293, 2018
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5O2O
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![BU of 5o2o by Molmil](/molmil-images/mine/5o2o) | Lytic transglycosylase in action | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Transglycosylase | Authors: | Williams, A.H, Hoauz, A, Boneca, I.G. | Deposit date: | 2017-05-22 | Release date: | 2018-06-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Lytic transglycosylase in action To Be Published
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5O1J
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![BU of 5o1j by Molmil](/molmil-images/mine/5o1j) | Lytic transglycosylase in action | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-1,6-anhydro-N-acetyl-beta-D-glucopyranosamine, Putative soluble lytic murein transglycosylase, ZINC ION | Authors: | Williams, A.H, Rateau, L, Hoauz, A, Boneca, I.G. | Deposit date: | 2017-05-18 | Release date: | 2018-03-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A step-by-stepin crystalloguide to bond cleavage and 1,6-anhydro-sugar product synthesis by a peptidoglycan-degrading lytic transglycosylase. J. Biol. Chem., 293, 2018
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4K40
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![BU of 4k40 by Molmil](/molmil-images/mine/4k40) | Peptidoglycan O-acetylesterase in action, 0 min | Descriptor: | GDSL-like Lipase/Acylhydrolase family protein | Authors: | Williams, A.H, Gompert Boneca, I. | Deposit date: | 2013-04-11 | Release date: | 2014-09-03 | Last modified: | 2017-06-21 | Method: | X-RAY DIFFRACTION (2.634 Å) | Cite: | Visualization of a substrate-induced productive conformation of the catalytic triad of the Neisseria meningitidis peptidoglycan O-acetylesterase reveals mechanistic conservation in SGNH esterase family members. Acta Crystallogr.,Sect.D, 70, 2014
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4K9S
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![BU of 4k9s by Molmil](/molmil-images/mine/4k9s) | Peptidoglycan O-acetylesterase in action, setmet | Descriptor: | GDSL-like Lipase/Acylhydrolase family protein | Authors: | Williams, A.H, Gompert Boneca, I. | Deposit date: | 2013-04-21 | Release date: | 2014-09-03 | Last modified: | 2014-10-22 | Method: | X-RAY DIFFRACTION (2.334 Å) | Cite: | Visualization of a substrate-induced productive conformation of the catalytic triad of the Neisseria meningitidis peptidoglycan O-acetylesterase reveals mechanistic conservation in SGNH esterase family members. Acta Crystallogr.,Sect.D, 70, 2014
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3I3A
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![BU of 3i3a by Molmil](/molmil-images/mine/3i3a) | Structural Basis for the Sugar Nucleotide and Acyl Chain Selectivity of Leptospira interrogans LpxA | Descriptor: | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, S-[2-({N-[(2R)-2-hydroxy-4-{[(S)-hydroxy(methoxy)phosphoryl]oxy}-3,3-dimethylbutanoyl]-beta-alanyl}amino)ethyl] (3R)-3-hydroxydodecanethioate | Authors: | Williams, A.H. | Deposit date: | 2009-06-30 | Release date: | 2009-09-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Structural basis for the sugar nucleotide and acyl-chain selectivity of Leptospira interrogans LpxA. Biochemistry, 48, 2009
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3I3X
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4K7J
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![BU of 4k7j by Molmil](/molmil-images/mine/4k7j) | Peptidoglycan O-acetylesterase in action, 5 min | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, GDSL-like Lipase/Acylhydrolase family protein | Authors: | Williams, A.H, Gomperts Boneca, I. | Deposit date: | 2013-04-17 | Release date: | 2014-09-03 | Last modified: | 2014-10-22 | Method: | X-RAY DIFFRACTION (1.968 Å) | Cite: | Visualization of a substrate-induced productive conformation of the catalytic triad of the Neisseria meningitidis peptidoglycan O-acetylesterase reveals mechanistic conservation in SGNH esterase family members. Acta Crystallogr.,Sect.D, 70, 2014
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4K3U
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![BU of 4k3u by Molmil](/molmil-images/mine/4k3u) | Peptidoglycan O-acetylesterase in action, 30 min | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GDSL-like Lipase/Acylhydrolase family protein | Authors: | Williams, A.H, Gomperts Boneca, I. | Deposit date: | 2013-04-11 | Release date: | 2014-09-03 | Last modified: | 2014-10-22 | Method: | X-RAY DIFFRACTION (2.158 Å) | Cite: | Visualization of a substrate-induced productive conformation of the catalytic triad of the Neisseria meningitidis peptidoglycan O-acetylesterase reveals mechanistic conservation in SGNH esterase family members. Acta Crystallogr.,Sect.D, 70, 2014
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3HSQ
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3T7H
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![BU of 3t7h by Molmil](/molmil-images/mine/3t7h) | Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway | Descriptor: | Ubiquitin-like modifier-activating enzyme ATG7 | Authors: | Taherbhoy, A.M, Tait, S.W, Kaiser, S.E, Williams, A.H, Deng, A, Nourse, A, Hammel, M, Kurinov, I, Rock, C.O, Green, D.R, Schulman, B.A. | Deposit date: | 2011-07-30 | Release date: | 2011-11-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Atg8 transfer from atg7 to atg3: a distinctive e1-e2 architecture and mechanism in the autophagy pathway. Mol.Cell, 44, 2011
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3T7G
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![BU of 3t7g by Molmil](/molmil-images/mine/3t7g) | Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway | Descriptor: | Autophagy-related protein 3, Ubiquitin-like modifier-activating enzyme ATG7 | Authors: | Taherbhoy, A.M, Tait, S.W, Kaiser, S.E, Williams, A.H, Deng, A, Nourse, A, Hammel, M, Kurinov, I, Rock, C.O, Green, D.R, Schulman, B.A. | Deposit date: | 2011-07-30 | Release date: | 2011-11-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Atg8 transfer from atg7 to atg3: a distinctive e1-e2 architecture and mechanism in the autophagy pathway. Mol.Cell, 44, 2011
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3T7E
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![BU of 3t7e by Molmil](/molmil-images/mine/3t7e) | Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway | Descriptor: | Ubiquitin-like modifier-activating enzyme ATG7, ZINC ION | Authors: | Taherbhoy, A.M, Tait, S.W, Kaiser, S.E, Williams, A.H, Deng, A, Nourse, A, Hammel, M, Kurinov, I, Rock, C.O, Green, D.R, Schulman, B.A. | Deposit date: | 2011-07-30 | Release date: | 2011-11-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Atg8 transfer from atg7 to atg3: a distinctive e1-e2 architecture and mechanism in the autophagy pathway. Mol.Cell, 44, 2011
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3T7F
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![BU of 3t7f by Molmil](/molmil-images/mine/3t7f) | Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway | Descriptor: | Ubiquitin-like modifier-activating enzyme ATG7 | Authors: | Taherbhoy, A.M, Tait, S.W, Kaiser, S.E, Williams, A.H, Deng, A, Nourse, A, Hammel, M, Kurinov, I, Rock, C.O, Green, D.R, Schulman, B.A. | Deposit date: | 2011-07-30 | Release date: | 2011-11-23 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Atg8 transfer from atg7 to atg3: a distinctive e1-e2 architecture and mechanism in the autophagy pathway. Mol.Cell, 44, 2011
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